Structure and inducing tumor cell apoptosis activity of polysaccharides isolated from Lentinus edodes

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 41, 2013, Pages 9849-9858

  Wang, Kai Ping ^a   Zhang, Qi Lin ^a   Liu, Ying ^a   Wang, Jun ^a   Cheng, Yao ^a   Zhang, Yu ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

antitumor activity; apoptosis; cytokine; Lentinus edodes; polysaccharides; structure

Indexed keywords

ANIMAL STUDIES; ANTI-TUMOR ACTIVITIES; ANTITUMOR EFFECT; ANTITUMOR MECHANISMS; CHEMICAL AND PHYSICAL ANALYSIS; CYTOKINES; LENTINUS EDODES; SIDE-CHAINS;

CELL DEATH; CHAINS; CHEMICAL ANALYSIS; MAMMALS; MOLECULAR WEIGHT DISTRIBUTION; STRUCTURE (COMPOSITION);

POLYSACCHARIDES;

POLYSACCHARIDE;

ANIMAL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; HUMAN; ISOLATION AND PURIFICATION; LENTINULA EDODES; MOLECULAR WEIGHT; MOUSE; NEOPLASM; PATHOPHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; NEOPLASMS; POLYSACCHARIDES; SHIITAKE MUSHROOMS;

EID: 84886909861     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf403291w     Document Type: Article

References (52)

1. Xie, J.; Liu, X.; Shen, M.; Nie, S.; Zhang, H.; Li, C.; Gong, D.; Xie, M. Purification, physicochemical characterisation and anticancer activity of a polysaccharide from Cyclocarya paliurus leaves Food Chem. 2013, 136, 1453-1460
2. Sarkar, F. H.; Li, Y. Using chemopreventive agents to enhance the efficacy of cancer therapy Cancer Res. 2006, 66, 3347-3350
3. Zhao, L.; Xiao, Y.; Xiao, N. Effect of lentinan combined with docetaxel and cisplatin on the proliferation and apoptosis of BGC823 cells Tumor Biol. 2013, 34, 1531-1536
4. Zhang, Y.; Li, S.; Wang, X.; Zhang, L.; Cheung, P. C. K. Advances in lentinan: isolation, structure, chain conformation and bioactivities Food Hydrocolloids 2011, 25, 196-206
5. Schepetkin, I. A.; Quinn, M. T. Botanical polysaccharides; macrophage immunomodulation and therapeutic potential Int. Immunopharmacol. 2006, 6, 317-333
6. Wasser, S. P. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides Appl. Microbiol. Biotechnol. 2002, 60, 258-274
7. Ikekawa, T.; Uehara, N.; Maeda, Y.; Nakanishi, M.; Fukuoka, F. Antitumor activity of aqueous extracts of edible mushrooms Cancer Res. 1969, 29, 734-735
8. Ferreira, I. C.; Vaz, J. A.; Vasconcelos, M. H.; Martins, A. Compounds from wild mushrooms with antitumor potential Anti-Cancer Agents Med. Chem. 2010, 10, 424-436
9. Jeff, I. B.; Zhou, Y.; Tai, G.; Li, S.; Peng, X.; Li, Z.; Kassim, R. M.; Liu, B. Purification, structural elucidation and antitumor activity of a novel mannogalactoglucan from the fruiting bodies of Lentinus edodes Fitoterapia 2012, 84, 338-346
10. Jagadish, L. K.; Shenbhagaraman, R.; Venkatakrishnan, V.; Kaviyarasan, V. Studies on the phytochemical, antioxidant and antimicrobial properties of three indigenous Pleurotus species J. Mol. Biol. Biotechnol. 2008, 1, 20-29
11. Makropoulou, M.; Aligiannis, N.; Gonou-Zagou, Z.; Pratsinis, H.; Skaltsounis, A. L.; Fokialakis, N. Antioxidant and cytotoxic activity of the wild edible mushroom Gomphus clavatus J. Med. Food 2012, 15, 216-221
12. You, R.; Wang, K.; Liu, J.; Liu, M.; Luo, L.; Zhang, Y. A comparison study between different molecular weight polysaccharides derived from Lentinus edodes and their antioxidant activities in vivo Pharm. Biol. 2011, 49, 1298-1305
13. Jeff, I. B.; Yuan, X.; Sun, L.; Kassim, R. M.; Foday, A. D.; Zhou, Y. Purification and in vitro anti-proliferative effect of novel neutral polysaccharides from Lentinus edodes Int. J. Biol. Macromol. 2013, 52, 99-106
14. Bhunia, S. K.; Dey, B.; Maity, K. K.; Patra, S.; Mandal, S.; Maiti, S.; Maiti, T. K.; Sikdar, S. R.; Islam, S. S. Isolation and characterization of an immunoenhancing glucan from alkaline extract of an edible mushroom, Lentinus squarrosulus (Mont.) Singer Carbohydr. Res. 2011, 346, 2039-2044
15. Ma, Z.; Wang, J.; Zhang, L.; Zhang, Y.; Ding, K. Evaluation of water soluble β-d-glucan from Auricularia auricular-judae as potential anti-tumor agent Carbohyd. Polym. 2010, 80, 977-983
16. Tian, Q. E.; Li, H. D.; Yan, M.; Cai, H. L.; Tan, Q. Y.; Zhang, W. Y. Astragalus polysaccharides can regulate cytokine and P-glycoprotein expression in H22 tumor-bearing mice World J. Gastroenterol. 2012, 18, 7079-7086
17. Falch, B. H.; Espevik, T.; Ryan, L.; Stokke, B. T. The cytokine stimulating activity of (1→3)-beta- d -glucans is dependent on the triple helix conformation Carbohydr. Res. 2000, 329, 587-596
18. Fang, N.; Li, Q.; Yu, S.; Zhang, J.; He, L.; Ronis, M. J.; Badger, T. M. Inhibition of growth and induction of apoptosis in human cancer cell lines by an ethyl acetate fraction from shiitake mushrooms J. Altern. Complement Med. 2006, 12, 125-132
19. Ding, X.; Zhu, F.; Gao, S. Purification, antitumour and immunomodulatory activity of water-extractable and alkali-extractable polysaccharides from Solanum nigrum L Food Chem. 2012, 131, 677-684
20. Zhang, L.; Li, X.; Xu, X.; Zeng, F. Correlation between antitumor activity, molecular weight, and conformation of lentinan Carbohydr. Res. 2005, 340, 1515-1521
21. Zhang, Y.; Ming, G.; Kaiping, W.; Zhixiang, C.; Liquan, D.; Jingyu, L.; Fang, Z. Structure, chain conformation and antitumor activity of a novel polysaccharide from Lentinus edodes Fitoterapia 2010, 81, 1163-1170
22. Dubois, M.; Gilles, K. A.; Hamilton, J. K.; Rebers, P. T.; Smith, F. Colorimetric method for determination of sugars and related substances Anal. Chem. 1956, 28, 350-356
23. Needs, P. W.; Selvendran, R. R. Avoiding oxidative degradation during sodium hydroxide/methyl iodide-mediated carbohydrate methylation in dimethyl sulfoxide Carbohydr. Res. 1993, 245, 1-10
24. Kassim, M.; Achoui, M.; Mustafa, M. R.; Mohd, M. A.; Yusoff, K. M. Ellagic acid, phenolic acids, and flavonoids in Malaysian honey extracts demonstrate in vitro anti-inflammatory activity Nutr. Res. (N. Y., NY, U. S.) 2010, 30, 650-659
25. Unursaikhan, S.; Xu, X.; Zeng, F.; Zhang, L. Antitumor activities of O-sulfonated derivatives of (1→3)-alpha- d -glucan from different Lentinus edodes Biosci., Biotechnol., Biochem. 2006, 70, 38-46
26. Maeda, Y. Y.; Watanabe, S. T.; Chihara, C.; Rokutanda, M. Denaturation and renaturation of a beta-1,6;1,3-glucan, lentinan, associated with expression of T-cell-mediated responses Cancer Res. 1988, 48, 671-675
27. Yanaki, T.; Ito, W.; Tabata, K.; Kojima, T.; Norisuye, T.; Takano, N.; Fujita, H. Correlation between the antitumor activity of a polysaccharide schizophyllan and its triple-helical conformation in dilute aqueous solution Biophys. Chem. 1983, 17, 337-342
28. Kalinowska-Lis, U.; Szmigiero, L.; Studzian, K.; Ochocki, J. Cytotoxic activity and chemical reactivity of cis-platinum(II) and trans-palladium(II) complexes with diethyl (pyridinylmethyl)phosphates Eur. J. Med. Chem. 2009, 44, 660-664
29. Marzano, C.; Sbovata, S. M.; Gandin, V.; Michelin, R. A.; Venzo, A.; Bertani, R.; Seraglia, R. Cytotoxicity of cis-platinum(II) cycloaliphatic amidine complexes: ring size and solvent effects on the biological activity J. Inorg. Biochem. 2009, 103, 1113-1119
30. Kim, H. Y.; Kim, J. H.; Yang, S. B.; Hong, S. G.; Lee, S. A.; Hwang, S. J.; Shin, K. S.; Suh, H. J.; Park, M. H. A polysaccharide extracted from rice bran fermented with Lentinus edodes enhances natural killer cell activity and exhibits anticancer effects J. Med. Food 2007, 10, 25-31
31. Wang, Y. Y.; Khoo, K. H.; Chen, S. T.; Lin, C. C.; Wong, C. H.; Lin, C. H. Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities Bioorg. Med. Chem. 2002, 10, 1057-1062
32. Ren, L.; Perera, C.; Hemar, Y. Antitumor activity of mushroom polysaccharides: a review Food Funct. 2012, 3, 1118-1130
33. Yang, L.; Zhang, L. Chemical structural and chain conformational characterization of some bioactive polysaccharides isolated from natural sources Carbohydr. Polym. 2009, 76, 349-361
34. Mizuno, T.; Yeohlui, P.; Kinoshita, T.; Zhuang, C.; Ito, H.; Mayuzumi, Y. Antitumor activity and chemical modification of polysaccharides from niohshimeji mushroom, Tricholma giganteum Biosci., Biotechnol., Biochem. 1996, 60, 30-33
35. Zhang, M.; Cui, S. W.; Cheung, P. C. K.; Wang, Q. Antitumor polysaccharides from mushrooms: a review on their isolation process, structural characteristics and antitumor activity Trends Food Sci. Technol. 2007, 18, 4-19
36. Rathee, S.; Rathee, D.; Rathee, D.; Kumar, V.; Rathee, P. Mushrooms as therapeutic agents Braz. J. Pharmacogn. 2012, 22, 459-474
37. Yang, X.; Zhao, Y.; Yang, Y.; Ruan, Y. Isolation and characterization of immunostimulatory polysaccharide from an herb tea, Gynostemma pentaphyllum Makino J. Agric. Food Chem. 2008, 56, 6905-6909
38. Fan, L.; Ding, S.; Ai, L.; Deng, K. Antitumor and immunomodulatory activity of water-soluble polysaccharide from Inonotus obliquus Carbohydr. Polym. 2012, 90, 870-874
39. Dhanji, S.; Teh, H. S. IL-2-activated CD8+CD44high cells express both adaptive and innate immune system receptors and demonstrate specificity for syngeneic tumor cells J. Immunol. 2003, 171, 3442-3450
40. Falch, B. H.; Espevik, T.; Ryan, L.; Stokke, B. T. The cytokine stimulating activity of (1→3)-beta- d -glucans is dependent on the triple helix conformation Carbohydr. Res. 2000, 329, 587-596
41. Li, W.; Nie, S.; Chen, Y.; Wang, Y.; Li, C.; Xie, M. Enhancement of cyclophosphamide-induced antitumor effect by a novel polysaccharide from Ganoderma atrum in sarcoma 180-bearing mice J. Agric. Food Chem. 2011, 59, 3707-3716
42. Zaidman, B. Z.; Yassin, M.; Mahajna, J.; Wasser, S. P. Medicinal mushroom modulators of molecular targets as cancer therapeutics Appl. Microbiol. Biotechnol. 2005, 67, 453-468
43. Li, W. J.; Chen, Y.; Nie, S. P.; Xie, M. Y.; He, M.; Zhang, S. S.; Zhu, K. X. Ganoderma atrum polysaccharide induces anti-tumor activity via the mitochondrial apoptotic pathway related to activation of host immune response J. Cell. Biochem. 2011, 112, 860-871
44. Wu, J.; Zhou, J.; Lang, Y.; Yao, L.; Xu, H.; Shi, H.; Xu, S. A polysaccharide from Armillaria mellea exhibits strong in vitro anticancer activity via apoptosis-involved mechanisms Int. J. Biol. Macromol. 2012, 51, 663-667
45. Park, D. K.; Park, H. J. Anti-proliferative properties of ethyl acetate extract of Phellinus linteus grown on ginseng (Panax ginseng) on HT-29 human colon carcinoma cells through inducing apoptosis Food Sci. Biotechnol. 2012, 21, 683-690
46. Huang, T.; Lin, J.; Cao, J.; Zhang, P.; Bai, Y.; Chen, G.; Chen, K. An exopolysaccharide from Trichoderma pseudokoningii and its apoptotic activity on human leukemia K562 cells Carbohydr. Polym. 2012, 89, 701-708
47. Finimundy, T. C.; Gambato, G.; Fontana, R.; Camassola, M.; Salvador, M.; Moura, S.; Hess, J.; Henriques, J. A.; Dillon, A. J.; Roesch-Ely, M. Aqueous extracts of Lentinula edodes and Pleurotus sajor-caju exhibit high antioxidant capability and promising in vitro antitumor activity Nutr. Res. (N. Y., NY, U. S.) 2013, 33, 76-84
48. Huang, Z.; Zhang, L.; Duan, X.; Liao, Z.; Ding, H.; Cheung, P. C. K. Novel highly branched water-soluble heteropolysaccharides as immunopotentiators to inhibit S-180 tumor cell growth in BALB/c mice Carbohydr. Polym. 2012, 87, 427-434
49. Lin, Z. B.; Zhang, H. N. Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms Acta Pharmacol. Sin. 2004, 25, 1387-1395
50. Li, W. J.; Chen, Y.; Nie, S. P.; Xie, M. Y.; He, M.; Zhang, S. S.; Zhu, K. X. Ganoderma atrum polysaccharide induces anti-tumor activity via the mitochondrial apoptotic pathway related to activation of host immune response J. Cell. Biochem. 2011, 112, 860-871
51. Liu, H.; Xiao, Y.; Xiong, C.; Wei, A.; Ruan, J. Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation Eur. J. Pharmacol. 2011, 654, 209-216
52. Jiang, J.; Slivova, V.; Harvey, K.; Valachovicova, T.; Sliva, D. Ganoderma lucidum suppresses growth of breast cancer cells through the inhibition of Akt/NF-κB signaling Nutr. Cancer 2004, 49, 209-216