Antitumor and immunomodulatory activity of water-soluble polysaccharide from Inonotus obliquus

Carbohydrate Polymers

Volumn 90, Issue 2, 2012, Pages 870-874

  Fan, Liuping ^a,b   Ding, Shaodong ^b   Ai, Lianzhong ^a   Deng, Kequan ^b  

^a Technology Center of Bright Dairy and Food Co Ltd   (China)

^b JIANGNAN UNIVERSITY   (China)

Author keywords

Antitumor; Immunomodulatory; Inonotus obliquus; Polysaccharides; Purification

Indexed keywords

ANTI-TUMOR ACTIVITIES; ANTI-TUMOR AGENTS; ANTI-TUMORS; CARDIO-VASCULAR DISEASE; IMMUNE RESPONSE; IMMUNOMODULATORY; IN-VIVO; INONOTUS OBLIQUUS; LYMPHOCYTE PROLIFERATION; MEDICINAL MUSHROOM; POTENTIAL APPLICATIONS; WATER-SOLUBLE POLYSACCHARIDES;

CELL PROLIFERATION; DISEASES; POLYSACCHARIDES; PURIFICATION;

DRUG PRODUCTS;

ANTINEOPLASTIC AGENT; FUNGAL POLYSACCHARIDE; IMMUNOLOGIC FACTOR; WATER;

AGARICALES; ANIMAL; ARTICLE; CARCINOMA; CELL CULTURE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECT; DRUG SCREENING; EVALUATION; FEMALE; HUMAN; ISOLATION AND PURIFICATION; MACROPHAGE ACTIVATION; MALE; MOLECULAR WEIGHT; MOUSE; NUDE MOUSE; PATHOLOGY; SOLUBILITY; STOMACH TUMOR; TUMOR CELL LINE;

AGARICALES; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; FEMALE; FUNGAL POLYSACCHARIDES; HUMANS; IMMUNOLOGIC FACTORS; MACROPHAGE ACTIVATION; MALE; MICE; MICE, NUDE; MOLECULAR WEIGHT; SOLUBILITY; STOMACH NEOPLASMS; WATER; XENOGRAFT MODEL ANTITUMOR ASSAYS;

BASIDIOMYCOTA; INONOTUS OBLIQUUS; MUS;

EID: 84864473606     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2012.06.013     Document Type: Article

References (26)

1. S. Ananthi, H.R.B. Raghavendran, A.G. Sunil, V. Gayathri, G. Ramakrishnan, and H.R. Vasanthi In vitro antioxidant and in vivo anti-inflammatory potential of crude polysaccharide from Turbinaria arnata (Marine Brown Alga) Food and Chemistry Toxicology 48 2010 187 192
2. A.T. Borchers, J.S. Stern, R.M. Hackman, C.L. Keen, and M.E. Gershwin Mushrooms, tumors, and immunity Experimental Biology and Medicine 221 1999 281 293 (Pubitemid 29386016)
3. R.Z. Chen, F. Meng, Z. Liu, R. Chen, and M. Zhang Antitumor activities of different fractions of polysaccharide purified from Ornithogalum caudatum Ait Carbohydrate Polymers 80 2010 845 851
4. Y. Chen, S. Huang, X. Gu, J. Tang, and J. Li Optimization of ultrasonic/microwave assisted extraction (UMAE) of polysaccharides from Inonotus obliquus and their antitumor activities International Journal of Biological Macromolecules 46 2010 429 435
5. X.Q. Cheng, H. Li, X.L. Yue, J.Y. Xie, Y.Y. Zhang, H.Y. Di, and D.F. Chen Macrophage immunomodulatory activity of the polysaccharides from the roots of Bupleurum smithii var. parvifolium Journal of Ethnopharmacology 130 2010 363 368
6. W.C.S. Cho, and K.N. Leung In vitro and in vivo antitumor effects of Astragalus membranaceus Cancer Letter 252 2007 43 54 (Pubitemid 46734552)
7. Y. Cui, D.S. Kim, and K.C. Park Antioxidant effect of Inonotus obliquus Journal of Ethnopharmacology 96 2005 79 85 (Pubitemid 39575034)
8. C.G. Katsiari, S.C. Liossis, and P.P. Sfikakis The pathophysiologic role of monocytes and macrophages in systemic lupus erythematosus: A reappraisal Seminars in Arthritis and Rheumatism 39 2010 491 503
9. Y.O. Kim, H.W. Park, J.H. Kim, J.Y. Lee, S.H. Moon, and C.S. Shin Anti-cancer effect and structural characterization of endo-polysaccharide from cultivated mycelia of Inonotus obliquus Life Sciences 79 2006 72 80 (Pubitemid 44255533)
10. J.W. Li, L.P. Fan, and S.D. Ding Isolation, purification and structure of a new water-soluble polysaccharide from Zizyphus jujuba cv. Jinsixiaozao[J] Carbohydrate Polymers 83 2011 477 482
11. J.W. Li, L. Shan, Y.F. Liu, L.P. Fan, and L.Z. Ai Screening of a functional polysaccharide from Zizyphus Jujuba cv. Jinsixiaozao and its property International Journal of Biological Macromolecules 49 2011 255 259
12. T. Mosmann Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays Journal of Immunology Methods 65 1983 55 63 (Pubitemid 14203433)
13. Y.F. Peng, L.N. Zhang, F. Zeng, and Y. Xu Structure and antitumor activity of extracellular polysaccharides from mycelium Carbohydrate Polymers 54 2003 297 303
14. D.L. Ren, J.Z. Wang, H. Noda, H. Amano, and S. Ogawa The effects of an algal polysaccharide from Gloiopeltis tenax on transplantable tumors and immune activities in mice Planta Medica 61 1995 120 125
15. M. Saar Fungi in Khanty fork medicine Journal of Ethnopharmacology 31 1991 175 179
16. I.A. Schepetkin, and M.T. Quinn Botanical polysaccharides: Macrophage immunomodulation and therapeutic potential International Immunopharmacology 6 2006 317 333 (Pubitemid 43120446)
17. J.C. Sheng, F. Yu, Z. Xin, L. Zhao, X. Zhu, and Q. Hu Preparation, identification and their antitumor activities in vitro of polysaccharides from Chlorella pyrenoidosa Food Chemistry 105 2007 533 539 (Pubitemid 47048544)
18. P.W. Solomon, and L.W. Alexander Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: A modern perspective Immunology 19 1999 65 96
19. J.E. Sun, Z.H. Ao, and Z.M. Lu Antihyperglycemicn and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice Journal of Ethnopharmacology 118 2008 7 13
20. Y. Sun, S. Wang, T. Li, X. Li, L. Jiao, and L. Zhang Purification, structure and immunobiological activity of a new water-soluble polysaccharide from the mycelium of Polyporus albicans (Imaz.) Teng Bioresource Technology 99 2008 900 904 (Pubitemid 350088459)
21. R. Tanaka, M. Toyoshima, and T. Yamada New lanostane-type triterpenoids, inonotsutriols D, and E, from Inonotus obliquus Phytochemistry Letters 4 2011 328 332
22. S.Y. Wang, M.L. Hsu, H.C. Hsu, C.H. Tzeng, S.S. Lee, and M.S. Shiao The antitumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes International Journal of Cancer 70 1997 699 705
23. S. Wasser Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides Applied Microbiology and Biotechnology 60 2003 258 274 (Pubitemid 35352092)
24. X.B. Yang, Y. Zhao, and Y. Lv In vivo macrophage activation and physicochemical property of the different polysaccharide fractions purified from Angelica sinensis Carbohydrate Polymers 71 2008 372 379 (Pubitemid 350181051)
25. C. Zhang, and K. Huang Characteristic immunostimulation by MAP, a polysaccharide isolated from the mucus of the loach, Misgurnus anguillicaudatus Carbohydrate Polymers 59 2005 75 82
26. G.F. Zhou, Y.P. Sun, H. Xin, Y. Zhang, Z. Li, and Z.H. Xu In vivo antitumor and immunomodulation activities of different molecular weight lambda-carrageenans from Chondrus ocellatus Pharmacological Research 50 2004 47 53 (Pubitemid 38479667)