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Volumn 40, Issue 5, 2013, Pages 554-566

Myeloma: Classification and risk assessment

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

EID: 84886891720     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2013.07.002     Document Type: Article
Times cited : (19)

References (113)
  • 1
    • 25844477041 scopus 로고    scopus 로고
    • Multiple myeloma: Diagnosis and treatment
    • S.V. Rajkumar, and R.A. Kyle Multiple myeloma: diagnosis and treatment Mayo Clin Proc 80 2005 1371 1382
    • (2005) Mayo Clin Proc , vol.80 , pp. 1371-1382
    • Rajkumar, S.V.1    Kyle, R.A.2
  • 2
    • 34447514656 scopus 로고    scopus 로고
    • Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma
    • S.V. Rajkumar, M.Q. Lacy, and R.A. Kyle Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma Blood Rev 21 2007 255 265
    • (2007) Blood Rev , vol.21 , pp. 255-265
    • Rajkumar, S.V.1    Lacy, M.Q.2    Kyle, R.A.3
  • 3
    • 67049162188 scopus 로고    scopus 로고
    • Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: A prospective study
    • O. Landgren, R.A. Kyle, and R.M. Pfeiffer Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study Blood 113 2009 5412 5417
    • (2009) Blood , vol.113 , pp. 5412-5417
    • Landgren, O.1    Kyle, R.A.2    Pfeiffer, R.M.3
  • 4
    • 67049114114 scopus 로고    scopus 로고
    • A monoclonal gammopathy precedes multiple myeloma in most patients
    • B.M. Weiss, J. Abadie, P. Verma, R.S. Howard, and W.M. Kuehl A monoclonal gammopathy precedes multiple myeloma in most patients Blood 113 2009 5418 5422
    • (2009) Blood , vol.113 , pp. 5418-5422
    • Weiss, B.M.1    Abadie, J.2    Verma, P.3    Howard, R.S.4    Kuehl, W.M.5
  • 5
    • 22044440425 scopus 로고    scopus 로고
    • Cyclin D dysregulation: An early and unifying pathogenic event in multiple myeloma
    • P.L. Bergsagel, W.M. Kuehl, F. Zhan, J. Sawyer, B. Barlogie, and J. Shaughnessy Jr Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma Blood 106 2005 296 303
    • (2005) Blood , vol.106 , pp. 296-303
    • Bergsagel, P.L.1    Kuehl, W.M.2    Zhan, F.3    Sawyer, J.4    Barlogie, B.5    Shaughnessy, Jr.J.6
  • 6
    • 20244363331 scopus 로고    scopus 로고
    • Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma
    • C. Debes-Marun, G. Dewald, and S. Bryant Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma Leukemia 17 2003 427 436
    • (2003) Leukemia , vol.17 , pp. 427-436
    • Debes-Marun, C.1    Dewald, G.2    Bryant, S.3
  • 7
    • 0141993685 scopus 로고    scopus 로고
    • Further cytogenetic characterization of multiple myeloma confirms that 14q32 translocations are a very rare event in hyperdiploid cases
    • N.V. Smadja, D. Leroux, and J. Soulier Further cytogenetic characterization of multiple myeloma confirms that 14q32 translocations are a very rare event in hyperdiploid cases Genes Chromosomes Cancer 38 2003 234 239
    • (2003) Genes Chromosomes Cancer , vol.38 , pp. 234-239
    • Smadja, N.V.1    Leroux, D.2    Soulier, J.3
  • 8
    • 0141481984 scopus 로고    scopus 로고
    • The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma
    • R. Fonseca, C.S. Debes-Marun, and E.B. Picken The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma Blood 102 2003 2562 2567
    • (2003) Blood , vol.102 , pp. 2562-2567
    • Fonseca, R.1    Debes-Marun, C.S.2    Picken, E.B.3
  • 9
    • 84876124577 scopus 로고    scopus 로고
    • Downregulation of specific miRNAs in hyperdiploid multiple myeloma mimics the oncogenic effect of IgH translocations occurring in the non-hyperdiploid subtype
    • A. Rio-Machin, B.I. Ferreira, and T. Henry Downregulation of specific miRNAs in hyperdiploid multiple myeloma mimics the oncogenic effect of IgH translocations occurring in the non-hyperdiploid subtype Leukemia 27 2013 925 931
    • (2013) Leukemia , vol.27 , pp. 925-931
    • Rio-Machin, A.1    Ferreira, B.I.2    Henry, T.3
  • 10
    • 34248201056 scopus 로고    scopus 로고
    • Molecular dissection of hyperdiploid multiple myeloma by gene expression profiling
    • W.J. Chng, S. Kumar, and S. Vanwier Molecular dissection of hyperdiploid multiple myeloma by gene expression profiling Cancer Res 67 2007 2982 2989
    • (2007) Cancer Res , vol.67 , pp. 2982-2989
    • Chng, W.J.1    Kumar, S.2    Vanwier, S.3
  • 11
    • 3042775298 scopus 로고    scopus 로고
    • Long-term follow-up of 241 patients with monoclonal gammopathy of undetermined significance: The original Mayo Clinic series 25 years later
    • R.A. Kyle, T.M. Therneau, S.V. Rajkumar, D.R. Larson, M.F. Plevak, and L.J. Melton 3rd Long-term follow-up of 241 patients with monoclonal gammopathy of undetermined significance: the original Mayo Clinic series 25 years later Mayo Clin Proc 79 2004 859 866
    • (2004) Mayo Clin Proc , vol.79 , pp. 859-866
    • Kyle, R.A.1    Therneau, T.M.2    Rajkumar, S.V.3    Larson, D.R.4    Plevak, M.F.5    Melton III, L.J.6
  • 12
    • 0032428365 scopus 로고    scopus 로고
    • Absence of p53 deletions in bone marrow plasma cells of patients with monoclonal gammopathy of undedetermined significance
    • J. Ackermann, P. Meidlinger, and N. Zojer Absence of p53 deletions in bone marrow plasma cells of patients with monoclonal gammopathy of undedetermined significance Br J Haematol 103 1998 1161 1163
    • (1998) Br J Haematol , vol.103 , pp. 1161-1163
    • Ackermann, J.1    Meidlinger, P.2    Zojer, N.3
  • 13
    • 8844266049 scopus 로고    scopus 로고
    • Both IGH translocations and chromosome 13q deletions are early events in monoclonal gammopathy of undetermined significance and do not evolve during transition to multiple myeloma
    • H. Kaufmann, J. Ackermann, and C. Baldia Both IGH translocations and chromosome 13q deletions are early events in monoclonal gammopathy of undetermined significance and do not evolve during transition to multiple myeloma Leukemia 18 2004 1879 1882
    • (2004) Leukemia , vol.18 , pp. 1879-1882
    • Kaufmann, H.1    Ackermann, J.2    Baldia, C.3
  • 14
    • 0033763998 scopus 로고    scopus 로고
    • Deletions of chromosome 13q in monoclonal gammopathy of undetermined significance
    • R. Konigsberg, J. Ackermann, and H. Kaufmann Deletions of chromosome 13q in monoclonal gammopathy of undetermined significance Leukemia 14 2000 1975 1979
    • (2000) Leukemia , vol.14 , pp. 1975-1979
    • Konigsberg, R.1    Ackermann, J.2    Kaufmann, H.3
  • 15
    • 24744434736 scopus 로고    scopus 로고
    • A validated FISH trisomy index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS
    • W.J. Chng, S.A. Van Wier, and G.J. Ahmann A validated FISH trisomy index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS Blood 106 2005 2156 2161
    • (2005) Blood , vol.106 , pp. 2156-2161
    • Chng, W.J.1    Van Wier, S.A.2    Ahmann, G.J.3
  • 16
    • 0037103287 scopus 로고    scopus 로고
    • Genomic abnormalities in monoclonal gammopathy of undetermined significance
    • R. Fonseca, R.J. Bailey, and G.J. Ahmann Genomic abnormalities in monoclonal gammopathy of undetermined significance Blood 100 2002 1417 1424
    • (2002) Blood , vol.100 , pp. 1417-1424
    • Fonseca, R.1    Bailey, R.J.2    Ahmann, G.J.3
  • 17
    • 34250694807 scopus 로고    scopus 로고
    • Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma
    • R.A. Kyle, E.D. Remstein, and T.M. Therneau Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma N Engl J Med 356 2007 2582 2590
    • (2007) N Engl J Med , vol.356 , pp. 2582-2590
    • Kyle, R.A.1    Remstein, E.D.2    Therneau, T.M.3
  • 18
    • 53449089919 scopus 로고    scopus 로고
    • Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma
    • K.M. Dhodapkar, S. Barbuto, and P. Matthews Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma Blood 112 2008 2878 2885
    • (2008) Blood , vol.112 , pp. 2878-2885
    • Dhodapkar, K.M.1    Barbuto, S.2    Matthews, P.3
  • 19
    • 67649729605 scopus 로고    scopus 로고
    • Myeloid neighborhood in myeloma: Cancer's underbelly?
    • M.V. Dhodapkar Myeloid neighborhood in myeloma: cancer's underbelly? Am J Hematol 84 2009 395 396
    • (2009) Am J Hematol , vol.84 , pp. 395-396
    • Dhodapkar, M.V.1
  • 20
    • 11144235574 scopus 로고    scopus 로고
    • Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition some plasma cell tumors
    • T. Rasmussen, M. Kuehl, M. Lodahl, H.E. Johnsen, and I.M. Dahl Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition some plasma cell tumors Blood 105 2005 317 323
    • (2005) Blood , vol.105 , pp. 317-323
    • Rasmussen, T.1    Kuehl, M.2    Lodahl, M.3    Johnsen, H.E.4    Dahl, I.M.5
  • 21
    • 57849129292 scopus 로고    scopus 로고
    • Clinical and biological significance of RAS mutations in multiple myeloma
    • W.J. Chng, N. Gonzalez-Paz, and T. Price-Troska Clinical and biological significance of RAS mutations in multiple myeloma Leukemia 22 2008 2280 2284
    • (2008) Leukemia , vol.22 , pp. 2280-2284
    • Chng, W.J.1    Gonzalez-Paz, N.2    Price-Troska, T.3
  • 22
    • 0029124138 scopus 로고
    • Introduction of an activated N-ras oncogene alters the growth characteristics of the interleukin 6-dependent myeloma cell line ANBL6
    • D. Billadeau, D.F. Jelinek, N. Shah, T.W. LeBien, and B. Van Ness Introduction of an activated N-ras oncogene alters the growth characteristics of the interleukin 6-dependent myeloma cell line ANBL6 Cancer Res 55 1995 3640 3646
    • (1995) Cancer Res , vol.55 , pp. 3640-3646
    • Billadeau, D.1    Jelinek, D.F.2    Shah, N.3    Lebien, T.W.4    Van Ness, B.5
  • 23
    • 31544457055 scopus 로고    scopus 로고
    • Risk of monoclonal gammopathy of undetermined significance (MGUS) and subsequent multiple myeloma among African American and white veterans in the United States
    • O. Landgren, G. Gridley, and I. Turesson Risk of monoclonal gammopathy of undetermined significance (MGUS) and subsequent multiple myeloma among African American and white veterans in the United States Blood 107 2006 904 906
    • (2006) Blood , vol.107 , pp. 904-906
    • Landgren, O.1    Gridley, G.2    Turesson, I.3
  • 24
    • 36148975380 scopus 로고    scopus 로고
    • Prevalence of monoclonal gammopathy of undetermined significance among men in Ghana
    • O. Landgren, J.A. Katzmann, and A.W. Hsing Prevalence of monoclonal gammopathy of undetermined significance among men in Ghana Mayo Clin Proc 82 2007 1468 1473
    • (2007) Mayo Clin Proc , vol.82 , pp. 1468-1473
    • Landgren, O.1    Katzmann, J.A.2    Hsing, A.W.3
  • 25
    • 70350097665 scopus 로고    scopus 로고
    • Patterns of monoclonal gammopathy of undetermined significance and multiple myeloma in various ethnic/racial groups: Support for genetic factors in pathogenesis
    • O. Landgren, and B.M. Weiss Patterns of monoclonal gammopathy of undetermined significance and multiple myeloma in various ethnic/racial groups: support for genetic factors in pathogenesis Leukemia 23 2009 1691 1697
    • (2009) Leukemia , vol.23 , pp. 1691-1697
    • Landgren, O.1    Weiss, B.M.2
  • 26
    • 84879144365 scopus 로고    scopus 로고
    • Uncovering the biology of multiple myeloma among African Americans: A comprehensive genomics approach
    • A. Baker, E. Braggio, and S. Jacobus Uncovering the biology of multiple myeloma among African Americans: a comprehensive genomics approach Blood 121 2013 3147 3152
    • (2013) Blood , vol.121 , pp. 3147-3152
    • Baker, A.1    Braggio, E.2    Jacobus, S.3
  • 27
    • 84859633476 scopus 로고    scopus 로고
    • Disparities in the prevalence, pathogenesis and progression of monoclonal gammopathy of undetermined significance and multiple myeloma between blacks and whites
    • A.J. Greenberg, C.M. Vachon, and S.V. Rajkumar Disparities in the prevalence, pathogenesis and progression of monoclonal gammopathy of undetermined significance and multiple myeloma between blacks and whites Leukemia 26 2012 609 614
    • (2012) Leukemia , vol.26 , pp. 609-614
    • Greenberg, A.J.1    Vachon, C.M.2    Rajkumar, S.V.3
  • 28
    • 79956088639 scopus 로고    scopus 로고
    • Patterns of monoclonal immunoglobulins and serum free light chains are significantly different in black compared to white monoclonal gammopathy of undetermined significance (MGUS) patients
    • B.M. Weiss, A. Minter, and J. Abadie Patterns of monoclonal immunoglobulins and serum free light chains are significantly different in black compared to white monoclonal gammopathy of undetermined significance (MGUS) patients Am J Hematol 86 2011 475 478
    • (2011) Am J Hematol , vol.86 , pp. 475-478
    • Weiss, B.M.1    Minter, A.2    Abadie, J.3
  • 29
    • 35948992626 scopus 로고    scopus 로고
    • Hyperdiploidy is a common finding in monoclonal gammopathy of undetermined significance and monosomy 13 is restricted to these hyperdiploid patients
    • M. Brousseau, X. Leleu, and J. Gerard Hyperdiploidy is a common finding in monoclonal gammopathy of undetermined significance and monosomy 13 is restricted to these hyperdiploid patients Clin Cancer Res 13 2007 6026 6031
    • (2007) Clin Cancer Res , vol.13 , pp. 6026-6031
    • Brousseau, M.1    Leleu, X.2    Gerard, J.3
  • 30
    • 33846417607 scopus 로고    scopus 로고
    • Upregulation of translational machinery and distinct genetic subgroups characterise hyperdiploidy in multiple myeloma
    • L. Agnelli, S. Fabris, and S. Bicciato Upregulation of translational machinery and distinct genetic subgroups characterise hyperdiploidy in multiple myeloma Br J Haematol 136 2007 565 573
    • (2007) Br J Haematol , vol.136 , pp. 565-573
    • Agnelli, L.1    Fabris, S.2    Bicciato, S.3
  • 31
    • 84886876697 scopus 로고    scopus 로고
    • Prognostic significance of the S-phase fraction of light chain restricted cytoplasmic immunoglobulin (cIg) positive plasma cells in patients with newly diagnosed multiple myeloma (meeting abstract)
    • M.C. Trendle, P.R. Greipp, and T. Leong Prognostic significance of the S-phase fraction of light chain restricted cytoplasmic immunoglobulin (cIg) positive plasma cells in patients with newly diagnosed multiple myeloma (meeting abstract) Proc Annu Meet Am Soc Clin Oncol 1996 15
    • (1996) Proc Annu Meet Am Soc Clin Oncol , pp. 15
    • Trendle, M.C.1    Greipp, P.R.2    Leong, T.3
  • 32
    • 0021792205 scopus 로고
    • The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia, or amyloidosis
    • G.W. Dewald, R.A. Kyle, G.A. Hicks, and P.R. Greipp The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia, or amyloidosis Blood 66 1985 380 390
    • (1985) Blood , vol.66 , pp. 380-390
    • Dewald, G.W.1    Kyle, R.A.2    Hicks, G.A.3    Greipp, P.R.4
  • 33
    • 0038142356 scopus 로고    scopus 로고
    • Clinical and biologic implications of recurrent genomic aberrations in myeloma
    • R. Fonseca, E. Blood, and M. Rue Clinical and biologic implications of recurrent genomic aberrations in myeloma Blood 101 2003 4569 4575
    • (2003) Blood , vol.101 , pp. 4569-4575
    • Fonseca, R.1    Blood, E.2    Rue, M.3
  • 34
    • 0037441747 scopus 로고    scopus 로고
    • In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression
    • J.J. Keats, T. Reiman, and C.A. Maxwell In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression Blood 101 2003 1520 1529
    • (2003) Blood , vol.101 , pp. 1520-1529
    • Keats, J.J.1    Reiman, T.2    Maxwell, C.A.3
  • 35
    • 0037085787 scopus 로고    scopus 로고
    • Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation
    • H. Avet-Loiseau, T. Facon, and B. Grosbois Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation Blood 99 2002 2185 2191
    • (2002) Blood , vol.99 , pp. 2185-2191
    • Avet-Loiseau, H.1    Facon, T.2    Grosbois, B.3
  • 36
    • 33847378314 scopus 로고    scopus 로고
    • Genetic abnormalities and survival in multiple myeloma: The experience of the Intergroupe Francophone du Myelome
    • H. Avet-Loiseau, M. Attal, and P. Moreau Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myelome Blood 109 2007 3489 3495
    • (2007) Blood , vol.109 , pp. 3489-3495
    • Avet-Loiseau, H.1    Attal, M.2    Moreau, P.3
  • 37
    • 1842557964 scopus 로고    scopus 로고
    • The t(4;14) is associated with poor prognosis in myeloma patients undergoing autologous stem cell transplant
    • H. Chang, S. Sloan, and D. Li The t(4;14) is associated with poor prognosis in myeloma patients undergoing autologous stem cell transplant Br J Haematol 125 2004 64 68
    • (2004) Br J Haematol , vol.125 , pp. 64-68
    • Chang, H.1    Sloan, S.2    Li, D.3
  • 38
    • 47549115250 scopus 로고    scopus 로고
    • VTD combination therapy with bortezomib-thalidomide-dexamethasone is highly effective in advanced and refractory multiple myeloma
    • M. Pineda-Roman, M. Zangari, and F. van Rhee VTD combination therapy with bortezomib-thalidomide-dexamethasone is highly effective in advanced and refractory multiple myeloma Leukemia 22 2008 1419 1427
    • (2008) Leukemia , vol.22 , pp. 1419-1427
    • Pineda-Roman, M.1    Zangari, M.2    Van Rhee, F.3
  • 39
    • 33947217497 scopus 로고    scopus 로고
    • A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
    • J.D. Shaughnessy Jr., F. Zhan, and B.E. Burington A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1 Blood 109 2007 2276 2284
    • (2007) Blood , vol.109 , pp. 2276-2284
    • Shaughnessy, Jr.J.D.1    Zhan, F.2    Burington, B.E.3
  • 40
    • 84875209671 scopus 로고    scopus 로고
    • Combining fluorescent in situ hybridization data with ISS staging improves risk assessment in myeloma: An International Myeloma Working Group collaborative project
    • H. Avet-Loiseau, B.G. Durie, and M. Cavo Combining fluorescent in situ hybridization data with ISS staging improves risk assessment in myeloma: an International Myeloma Working Group collaborative project Leukemia 27 2013 711 717
    • (2013) Leukemia , vol.27 , pp. 711-717
    • Avet-Loiseau, H.1    Durie, B.G.2    Cavo, M.3
  • 41
    • 0001070363 scopus 로고    scopus 로고
    • Prognostic significance of 13q- deletions and the t(11;14)(q13;q32) in myeloma (MM); An interphase FISH Study of 351 patients entered into the Eastern Cooperative Oncology Group E9487 clinical trial
    • R. Fonseca, D. Harrington, and M.M. Oken Prognostic significance of 13q- deletions and the t(11;14)(q13;q32) in myeloma (MM); an interphase FISH Study of 351 patients entered into the Eastern Cooperative Oncology Group E9487 clinical trial Blood 96 2000 547a
    • (2000) Blood , vol.96
    • Fonseca, R.1    Harrington, D.2    Oken, M.M.3
  • 42
    • 0024501542 scopus 로고
    • Nonrandom rearrangement of chromosome 14 at band q32.33 in human lymphoid malignancies with mature B-cell phenotype
    • K. Nishida, M. Taniwaki, S. Misawa, and T. Abe Nonrandom rearrangement of chromosome 14 at band q32.33 in human lymphoid malignancies with mature B-cell phenotype Cancer Res 49 1989 1275 1281
    • (1989) Cancer Res , vol.49 , pp. 1275-1281
    • Nishida, K.1    Taniwaki, M.2    Misawa, S.3    Abe, T.4
  • 43
    • 0029978550 scopus 로고    scopus 로고
    • Dysregulation of cyclin D1 by translocation into an IgH gamma switch region in two multiple myeloma cell lines
    • M. Chesi, P.L. Bergsagel, L.A. Brents, C.M. Smith, D.S. Gerhard, and W.M. Kuehl Dysregulation of cyclin D1 by translocation into an IgH gamma switch region in two multiple myeloma cell lines Blood 88 1996 674 681
    • (1996) Blood , vol.88 , pp. 674-681
    • Chesi, M.1    Bergsagel, P.L.2    Brents, L.A.3    Smith, C.M.4    Gerhard, D.S.5    Kuehl, W.M.6
  • 44
    • 0033568514 scopus 로고    scopus 로고
    • 14q32 translocations and monosomy 13 observed in monoclonal gammopathy of undetermined significance delineate a multistep process for the oncogenesis of multiple myeloma
    • H. Avet-Loiseau, T. Facon, and A. Daviet 14q32 translocations and monosomy 13 observed in monoclonal gammopathy of undetermined significance delineate a multistep process for the oncogenesis of multiple myeloma Intergroupe Francophone du Myelome. Cancer Res 59 1999 4546 4550
    • (1999) Intergroupe Francophone du Myelome. Cancer Res , vol.59 , pp. 4546-4550
    • Avet-Loiseau, H.1    Facon, T.2    Daviet, A.3
  • 45
    • 33745779502 scopus 로고    scopus 로고
    • The molecular classification of multiple myeloma
    • F. Zhan, Y. Huang, and S. Colla The molecular classification of multiple myeloma Blood 108 2006 2020 2028
    • (2006) Blood , vol.108 , pp. 2020-2028
    • Zhan, F.1    Huang, Y.2    Colla, S.3
  • 46
    • 43749090639 scopus 로고    scopus 로고
    • Genetic aberrations and survival in plasma cell leukemia
    • R.E. Tiedemann, N. Gonzalez-Paz, and R.A. Kyle Genetic aberrations and survival in plasma cell leukemia Leukemia 22 2008 1044 1052
    • (2008) Leukemia , vol.22 , pp. 1044-1052
    • Tiedemann, R.E.1    Gonzalez-Paz, N.2    Kyle, R.A.3
  • 47
    • 0035496937 scopus 로고    scopus 로고
    • Translocations involving heavy-chain locus are possible early genetic events in patients with primary systemic amyloidosis
    • S.R. Hayman, R.J. Bailey, and S.M. Jalal Translocations involving heavy-chain locus are possible early genetic events in patients with primary systemic amyloidosis Blood 98 2001 2266 2268
    • (2001) Blood , vol.98 , pp. 2266-2268
    • Hayman, S.R.1    Bailey, R.J.2    Jalal, S.M.3
  • 49
    • 0030922231 scopus 로고    scopus 로고
    • Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3
    • M. Chesi, E. Nardini, and L.A. Brents Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3 Nature Genet 16 1997 260 264
    • (1997) Nature Genet , vol.16 , pp. 260-264
    • Chesi, M.1    Nardini, E.2    Brents, L.A.3
  • 50
    • 0031839633 scopus 로고    scopus 로고
    • Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma
    • M. Chesi, P.L. Bergsagel, and O.O. Shonukan Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma Blood 91 1998 4457 4463
    • (1998) Blood , vol.91 , pp. 4457-4463
    • Chesi, M.1    Bergsagel, P.L.2    Shonukan, O.O.3
  • 51
    • 78049501226 scopus 로고    scopus 로고
    • Bortezomib plus dexamethasone induction improves outcome of patients with t(4;14) myeloma but not outcome of patients with del(17p)
    • H. Avet-Loiseau, X. Leleu, and M. Roussel Bortezomib plus dexamethasone induction improves outcome of patients with t(4;14) myeloma but not outcome of patients with del(17p) J Clin Oncol 28 2010 4630 4634
    • (2010) J Clin Oncol , vol.28 , pp. 4630-4634
    • Avet-Loiseau, H.1    Leleu, X.2    Roussel, M.3
  • 52
    • 79951504474 scopus 로고    scopus 로고
    • Translocation t(14;16) and multiple myeloma: Is it really an independent prognostic factor?
    • H. Avet-Loiseau, F. Malard, and L. Campion Translocation t(14;16) and multiple myeloma: is it really an independent prognostic factor? Blood 117 2011 2009 2011
    • (2011) Blood , vol.117 , pp. 2009-2011
    • Avet-Loiseau, H.1    Malard, F.2    Campion, L.3
  • 53
    • 74049162897 scopus 로고    scopus 로고
    • International Myeloma Working Group molecular classification of multiple myeloma: Spotlight review
    • R. Fonseca, P.L. Bergsagel, and J. Drach International Myeloma Working Group molecular classification of multiple myeloma: spotlight review Leukemia 23 2009 2210 2221
    • (2009) Leukemia , vol.23 , pp. 2210-2221
    • Fonseca, R.1    Bergsagel, P.L.2    Drach, J.3
  • 54
    • 58149165366 scopus 로고    scopus 로고
    • An analysis of the clinical and biologic significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma
    • W. Xiong, X. Wu, and S. Starnes An analysis of the clinical and biologic significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma Blood 112 2008 4235 4246
    • (2008) Blood , vol.112 , pp. 4235-4246
    • Xiong, W.1    Wu, X.2    Starnes, S.3
  • 55
    • 0032147210 scopus 로고    scopus 로고
    • Presence of a p53 gene deletion in patients with multiple myeloma predicts for short survival after conventional-dose chemotherapy
    • J. Drach, J. Ackermann, and E. Fritz Presence of a p53 gene deletion in patients with multiple myeloma predicts for short survival after conventional-dose chemotherapy Blood 92 1998 802 809
    • (1998) Blood , vol.92 , pp. 802-809
    • Drach, J.1    Ackermann, J.2    Fritz, E.3
  • 56
    • 34547660308 scopus 로고    scopus 로고
    • Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma
    • J.J. Keats, R. Fonseca, and M. Chesi Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma Cancer Cell 12 2007 131 144
    • (2007) Cancer Cell , vol.12 , pp. 131-144
    • Keats, J.J.1    Fonseca, R.2    Chesi, M.3
  • 57
    • 33645769276 scopus 로고    scopus 로고
    • High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients
    • D.R. Carrasco, G. Tonon, and Y. Huang High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients Cancer Cell 9 2006 313 325
    • (2006) Cancer Cell , vol.9 , pp. 313-325
    • Carrasco, D.R.1    Tonon, G.2    Huang, Y.3
  • 58
    • 33847224187 scopus 로고    scopus 로고
    • Clinical significance of TP53 mutation in myeloma
    • W.J. Chng, T. Price-Troska, and N. Gonzalez-Paz Clinical significance of TP53 mutation in myeloma Leukemia 21 2007 582 584
    • (2007) Leukemia , vol.21 , pp. 582-584
    • Chng, W.J.1    Price-Troska, T.2    Gonzalez-Paz, N.3
  • 59
    • 11144219996 scopus 로고    scopus 로고
    • P53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation
    • H. Chang, C. Qi, Q.L. Yi, D. Reece, and A.K. Stewart p53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation Blood 105 2005 358 360
    • (2005) Blood , vol.105 , pp. 358-360
    • Chang, H.1    Qi, C.2    Yi, Q.L.3    Reece, D.4    Stewart, A.K.5
  • 60
    • 33748196399 scopus 로고    scopus 로고
    • Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: Incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation
    • I. Hanamura, J.P. Stewart, and Y. Huang Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation Blood 108 2006 1724 1732
    • (2006) Blood , vol.108 , pp. 1724-1732
    • Hanamura, I.1    Stewart, J.P.2    Huang, Y.3
  • 61
    • 33750327901 scopus 로고    scopus 로고
    • Prognostic value of chromosome 1q21 gain by fluorescent in situ hybridization and increase CKS1B expression in myeloma
    • R. Fonseca, S.A. Van Wier, and W.J. Chng Prognostic value of chromosome 1q21 gain by fluorescent in situ hybridization and increase CKS1B expression in myeloma Leukemia 20 2006 2034 2040
    • (2006) Leukemia , vol.20 , pp. 2034-2040
    • Fonseca, R.1    Van Wier, S.A.2    Chng, W.J.3
  • 62
    • 79951494668 scopus 로고    scopus 로고
    • Initial genome sequencing and analysis of multiple myeloma
    • M.A. Chapman, M.S. Lawrence, and J.J. Keats Initial genome sequencing and analysis of multiple myeloma Nature 471 2011 467 472
    • (2011) Nature , vol.471 , pp. 467-472
    • Chapman, M.A.1    Lawrence, M.S.2    Keats, J.J.3
  • 63
    • 79958095463 scopus 로고    scopus 로고
    • Clinical and biological implications of MYC activation: A common difference between MGUS and newly diagnosed multiple myeloma
    • W.J. Chng, G.F. Huang, and T.H. Chung Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma Leukemia 25 2011 1026 1035
    • (2011) Leukemia , vol.25 , pp. 1026-1035
    • Chng, W.J.1    Huang, G.F.2    Chung, T.H.3
  • 64
    • 44349090331 scopus 로고    scopus 로고
    • Secondary genomic rearrangements involving immunoglobulin or MYC loci show similar prevalences in hyperdiploid and nonhyperdiploid myeloma tumors
    • A. Gabrea, M.L. Martelli, and Y. Qi Secondary genomic rearrangements involving immunoglobulin or MYC loci show similar prevalences in hyperdiploid and nonhyperdiploid myeloma tumors Genes Chromosomes Cancer 47 2008 573 590
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 573-590
    • Gabrea, A.1    Martelli, M.L.2    Qi, Y.3
  • 65
    • 0035892119 scopus 로고    scopus 로고
    • Rearrangements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors
    • H. Avet-Loiseau, F. Gerson, F. Magrangeas, S. Minvielle, J.L. Harousseau, and R. Bataille Rearrangements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors Blood 98 2001 3082 3086
    • (2001) Blood , vol.98 , pp. 3082-3086
    • Avet-Loiseau, H.1    Gerson, F.2    Magrangeas, F.3    Minvielle, S.4    Harousseau, J.L.5    Bataille, R.6
  • 66
    • 0035496928 scopus 로고    scopus 로고
    • Hypodiploidy is a major prognostic factor in multiple myeloma
    • N.V. Smadja, C. Bastard, C. Brigaudeau, D. Leroux, and C. Fruchart Hypodiploidy is a major prognostic factor in multiple myeloma Blood 98 2001 2229 2238
    • (2001) Blood , vol.98 , pp. 2229-2238
    • Smadja, N.V.1    Bastard, C.2    Brigaudeau, C.3    Leroux, D.4    Fruchart, C.5
  • 67
    • 0021879375 scopus 로고
    • Prognostic implications of tumor cell DNA and RNA content in multiple myeloma
    • B. Barlogie, R. Alexanian, D. Dixon, L. Smith, L. Smallwood, and K. Delasalle Prognostic implications of tumor cell DNA and RNA content in multiple myeloma Blood 66 1985 338 341
    • (1985) Blood , vol.66 , pp. 338-341
    • Barlogie, B.1    Alexanian, R.2    Dixon, D.3    Smith, L.4    Smallwood, L.5    Delasalle, K.6
  • 68
    • 0030825598 scopus 로고    scopus 로고
    • Hypodiploidy and 22q11 rearrangements at diagnosis are associated with poor prognosis in patients with multiple myeloma
    • M.J. Calasanz, J.C. Cigudosa, and M.D. Odero Hypodiploidy and 22q11 rearrangements at diagnosis are associated with poor prognosis in patients with multiple myeloma Br J Haematol 98 1997 418 425
    • (1997) Br J Haematol , vol.98 , pp. 418-425
    • Calasanz, M.J.1    Cigudosa, J.C.2    Odero, M.D.3
  • 69
    • 18544363372 scopus 로고    scopus 로고
    • Both hypodiploidy and deletion of chromosome 13 independently confer poor prognosis in multiple myeloma
    • A.B. Fassas, T. Spencer, and J. Sawyer Both hypodiploidy and deletion of chromosome 13 independently confer poor prognosis in multiple myeloma Br J Haematol 118 2002 1041 1047
    • (2002) Br J Haematol , vol.118 , pp. 1041-1047
    • Fassas, A.B.1    Spencer, T.2    Sawyer, J.3
  • 70
    • 0024551187 scopus 로고
    • Detection of hypodiploidy using multi-parameter flow cytometric analysis: A prognostic indicator in multiple myeloma
    • R.J. Morgan Jr., N.J. Gonchoroff, J.A. Katzmann, T.E. Witzig, R.A. Kyle, and P.R. Greipp Detection of hypodiploidy using multi-parameter flow cytometric analysis: a prognostic indicator in multiple myeloma Am J Hematol 30 1989 195 200
    • (1989) Am J Hematol , vol.30 , pp. 195-200
    • Morgan, Jr.R.J.1    Gonchoroff, N.J.2    Katzmann, J.A.3    Witzig, T.E.4    Kyle, R.A.5    Greipp, P.R.6
  • 71
    • 84884953416 scopus 로고    scopus 로고
    • Hypodiploid multiple myeloma is characterized by more aggressive molecular markers than non-hyperdiploid multiple myeloma
    • Epub ahead of print
    • S. Van Wier, E. Braggio, and A. Baker Hypodiploid multiple myeloma is characterized by more aggressive molecular markers than non-hyperdiploid multiple myeloma Haematologica 2013 Epub ahead of print
    • (2013) Haematologica
    • Van Wier, S.1    Braggio, E.2    Baker, A.3
  • 72
    • 38949203768 scopus 로고    scopus 로고
    • The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that might benefit from aurora kinase inhibition
    • W.J. Chng, E. Braggio, and G. Mulligan The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that might benefit from aurora kinase inhibition Blood 111 2008 1603 1609
    • (2008) Blood , vol.111 , pp. 1603-1609
    • Chng, W.J.1    Braggio, E.2    Mulligan, G.3
  • 73
    • 54249092519 scopus 로고    scopus 로고
    • Prediction of survival in multiple myeloma based on gene expression profiles reveals cell cycle and chromosomal instability signatures in high-risk patients and hyperdiploid signatures in low-risk patients: A study of the Intergroupe Francophone du Myelome
    • O. Decaux, L. Lode, and F. Magrangeas Prediction of survival in multiple myeloma based on gene expression profiles reveals cell cycle and chromosomal instability signatures in high-risk patients and hyperdiploid signatures in low-risk patients: a study of the Intergroupe Francophone du Myelome J Clin Oncol 26 2008 4798 4805
    • (2008) J Clin Oncol , vol.26 , pp. 4798-4805
    • Decaux, O.1    Lode, L.2    Magrangeas, F.3
  • 74
    • 70249110853 scopus 로고    scopus 로고
    • Gene expression profiles of tumor biology provide a novel approach to prognosis and may guide the selection of therapeutic targets in multiple myeloma
    • A. Anguiano, S.A. Tuchman, and C. Acharya Gene expression profiles of tumor biology provide a novel approach to prognosis and may guide the selection of therapeutic targets in multiple myeloma J Clin Oncol 27 2009 4197 4203
    • (2009) J Clin Oncol , vol.27 , pp. 4197-4203
    • Anguiano, A.1    Tuchman, S.A.2    Acharya, C.3
  • 75
    • 77957733923 scopus 로고    scopus 로고
    • Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients
    • A. Broyl, D. Hose, and H. Lokhorst Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients Blood 116 2010 2543 2553
    • (2010) Blood , vol.116 , pp. 2543-2553
    • Broyl, A.1    Hose, D.2    Lokhorst, H.3
  • 76
    • 34147129816 scopus 로고    scopus 로고
    • Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib
    • G. Mulligan, C. Mitsiades, and B. Bryant Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib Blood 109 2007 3177 3188
    • (2007) Blood , vol.109 , pp. 3177-3188
    • Mulligan, G.1    Mitsiades, C.2    Bryant, B.3
  • 77
    • 77953632707 scopus 로고    scopus 로고
    • Superior results of Total Therapy 3 (2003-33) in gene expression profiling-defined low-risk multiple myeloma confirmed in subsequent trial. 2006-66 with VRD maintenance
    • B. Nair, F. van Rhee, and J.D. Shaughnessy Jr. Superior results of Total Therapy 3 (2003-33) in gene expression profiling-defined low-risk multiple myeloma confirmed in subsequent trial. 2006-66 with VRD maintenance Blood 115 2010 4168 4173
    • (2010) Blood , vol.115 , pp. 4168-4173
    • Nair, B.1    Van Rhee, F.2    Shaughnessy, Jr.J.D.3
  • 78
    • 38949113714 scopus 로고    scopus 로고
    • Bortezomib down-regulates the cell-surface expression of HLA class i and enhances natural killer cell-mediated lysis of myeloma
    • J. Shi, G.J. Tricot, and T.K. Garg Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma Blood 111 2008 1309 1317
    • (2008) Blood , vol.111 , pp. 1309-1317
    • Shi, J.1    Tricot, G.J.2    Garg, T.K.3
  • 79
    • 84869085660 scopus 로고    scopus 로고
    • A gene expression signature for high-risk multiple myeloma
    • R. Kuiper, A. Broyl, and Y. de Knegt A gene expression signature for high-risk multiple myeloma Leukemia 26 2012 2406 2413
    • (2012) Leukemia , vol.26 , pp. 2406-2413
    • Kuiper, R.1    Broyl, A.2    De Knegt, Y.3
  • 80
    • 74549190701 scopus 로고    scopus 로고
    • Prognostic significance of copy-number alterations in multiple myeloma
    • H. Avet-Loiseau, C. Li, and F. Magrangeas Prognostic significance of copy-number alterations in multiple myeloma J Clin Oncol 27 2009 4585 4590
    • (2009) J Clin Oncol , vol.27 , pp. 4585-4590
    • Avet-Loiseau, H.1    Li, C.2    Magrangeas, F.3
  • 81
    • 84869822590 scopus 로고    scopus 로고
    • Resequencing analysis of the candidate tyrosine kinase and RAS pathway gene families in multiple myeloma
    • V. Hucthagowder, R. Meyer, and C. Mullins Resequencing analysis of the candidate tyrosine kinase and RAS pathway gene families in multiple myeloma Cancer Genet 205 2012 474 478
    • (2012) Cancer Genet , vol.205 , pp. 474-478
    • Hucthagowder, V.1    Meyer, R.2    Mullins, C.3
  • 82
    • 84861532638 scopus 로고    scopus 로고
    • Clonal competition with alternating dominance in multiple myeloma
    • J.J. Keats, M. Chesi, and J.B. Egan Clonal competition with alternating dominance in multiple myeloma Blood 120 2012 1067 1076
    • (2012) Blood , vol.120 , pp. 1067-1076
    • Keats, J.J.1    Chesi, M.2    Egan, J.B.3
  • 83
    • 84864544413 scopus 로고    scopus 로고
    • Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma
    • B.A. Walker, C.P. Wardell, and L. Melchor Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma Blood 120 2012 1077 1086
    • (2012) Blood , vol.120 , pp. 1077-1086
    • Walker, B.A.1    Wardell, C.P.2    Melchor, L.3
  • 84
    • 84860219443 scopus 로고    scopus 로고
    • The genetic architecture of multiple myeloma
    • G.J. Morgan, B.A. Walker, and F.E. Davies The genetic architecture of multiple myeloma Nat Rev Cancer 12 2012 335 348
    • (2012) Nat Rev Cancer , vol.12 , pp. 335-348
    • Morgan, G.J.1    Walker, B.A.2    Davies, F.E.3
  • 85
    • 84879266916 scopus 로고    scopus 로고
    • A novel measure of chromosome instability can account for prognostic difference in multiple myeloma
    • T.-H. Chung, G. Mulligan, R. Fonseca, and W.-J. Chng A novel measure of chromosome instability can account for prognostic difference in multiple myeloma PLoS One 8 2013 e66361
    • (2013) PLoS One , vol.8 , pp. 66361
    • Chung, T.-H.1    Mulligan, G.2    Fonseca, R.3    Chng, W.-J.4
  • 86
    • 84873048466 scopus 로고    scopus 로고
    • High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance
    • A. Broyl, R. Kuiper, and M. van Duin High cereblon expression is associated with better survival in patients with newly diagnosed multiple myeloma treated with thalidomide maintenance Blood 121 2013 624 627
    • (2013) Blood , vol.121 , pp. 624-627
    • Broyl, A.1    Kuiper, R.2    Van Duin, M.3
  • 87
    • 84877796962 scopus 로고    scopus 로고
    • Extramedullary myeloma whole genome sequencing reveals novel mutations in Cereblon, proteasome subunit G2 and the glucocorticoid receptor in multi drug resistant disease
    • J.B. Egan, K.M. Kortuem, and A. Kurdoglu Extramedullary myeloma whole genome sequencing reveals novel mutations in Cereblon, proteasome subunit G2 and the glucocorticoid receptor in multi drug resistant disease Br J Haematol 161 2013 748 751
    • (2013) Br J Haematol , vol.161 , pp. 748-751
    • Egan, J.B.1    Kortuem, K.M.2    Kurdoglu, A.3
  • 88
    • 84865171981 scopus 로고    scopus 로고
    • Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: Results of the randomized phase III HOVON-65/ GMMG-HD4 trial
    • P. Sonneveld, I.G. Schmidt-Wolf, and B. van der Holt Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial J Clin Oncol 30 2012 2946 2955
    • (2012) J Clin Oncol , vol.30 , pp. 2946-2955
    • Sonneveld, P.1    Schmidt-Wolf, I.G.2    Van Der Holt, B.3
  • 89
    • 84856278440 scopus 로고    scopus 로고
    • Administration of bortezomib before and after autologous stem cell transplantation improves outcome in multiple myeloma patients with deletion 17p
    • K. Neben, H.M. Lokhorst, and A. Jauch Administration of bortezomib before and after autologous stem cell transplantation improves outcome in multiple myeloma patients with deletion 17p Blood 119 2012 940 948
    • (2012) Blood , vol.119 , pp. 940-948
    • Neben, K.1    Lokhorst, H.M.2    Jauch, A.3
  • 90
    • 84863576232 scopus 로고    scopus 로고
    • Bortezomib-thalidomide-dexamethasone is superior to thalidomide- dexamethasone as consolidation therapy after autologous hematopoietic stem cell transplantation in patients with newly diagnosed multiple myeloma
    • M. Cavo, L. Pantani, and M.T. Petrucci Bortezomib-thalidomide- dexamethasone is superior to thalidomide-dexamethasone as consolidation therapy after autologous hematopoietic stem cell transplantation in patients with newly diagnosed multiple myeloma Blood 120 2012 9 19
    • (2012) Blood , vol.120 , pp. 9-19
    • Cavo, M.1    Pantani, L.2    Petrucci, M.T.3
  • 91
    • 50449086728 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
    • J.F. San Miguel, R. Schlag, and N.K. Khuageva Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma N Engl J Med 359 2008 906 917
    • (2008) N Engl J Med , vol.359 , pp. 906-917
    • San Miguel, J.F.1    Schlag, R.2    Khuageva, N.K.3
  • 92
    • 84866851061 scopus 로고    scopus 로고
    • Maintenance therapy with bortezomib plus thalidomide or bortezomib plus prednisone in elderly multiple myeloma patients included in the GEM2005MAS65 trial
    • M.V. Mateos, A. Oriol, and J. Martinez-Lopez Maintenance therapy with bortezomib plus thalidomide or bortezomib plus prednisone in elderly multiple myeloma patients included in the GEM2005MAS65 trial Blood 120 2012 2581 2588
    • (2012) Blood , vol.120 , pp. 2581-2588
    • Mateos, M.V.1    Oriol, A.2    Martinez-Lopez, J.3
  • 93
    • 84865444078 scopus 로고    scopus 로고
    • Superiority of bortezomib, thalidomide, and dexamethasone (VTD) as induction pretransplantation therapy in multiple myeloma: A randomized phase 3 PETHEMA/GEM study
    • L. Rosinol, A. Oriol, and A.I. Teruel Superiority of bortezomib, thalidomide, and dexamethasone (VTD) as induction pretransplantation therapy in multiple myeloma: a randomized phase 3 PETHEMA/GEM study Blood 120 2012 1589 1596
    • (2012) Blood , vol.120 , pp. 1589-1596
    • Rosinol, L.1    Oriol, A.2    Teruel, A.I.3
  • 94
    • 33847197966 scopus 로고    scopus 로고
    • A practical guide to defining high-risk myeloma for clinical trials, patient counseling and choice of therapy
    • A.K. Stewart, P.L. Bergsagel, and P.R. Greipp A practical guide to defining high-risk myeloma for clinical trials, patient counseling and choice of therapy Leukemia 21 2007 529 534
    • (2007) Leukemia , vol.21 , pp. 529-534
    • Stewart, A.K.1    Bergsagel, P.L.2    Greipp, P.R.3
  • 95
    • 37249040444 scopus 로고    scopus 로고
    • Benefit of complete response in multiple myeloma limited to high-risk subgroup identified by gene expression profiling
    • J. Haessler, J.D. Shaughnessy Jr., and F. Zhan Benefit of complete response in multiple myeloma limited to high-risk subgroup identified by gene expression profiling Clin Cancer Res 13 2007 7073 7079
    • (2007) Clin Cancer Res , vol.13 , pp. 7073-7079
    • Haessler, J.1    Shaughnessy, Jr.J.D.2    Zhan, F.3
  • 96
    • 27144441760 scopus 로고    scopus 로고
    • Clinical implications of t(11;14)(q13;q32), t(4;14)(p16.3;q32), and -17p13 in myeloma patients treated with high-dose therapy
    • M.A. Gertz, M.Q. Lacy, and A. Dispenzieri Clinical implications of t(11;14)(q13;q32), t(4;14)(p16.3;q32), and -17p13 in myeloma patients treated with high-dose therapy Blood 106 2005 2837 2840
    • (2005) Blood , vol.106 , pp. 2837-2840
    • Gertz, M.A.1    Lacy, M.Q.2    Dispenzieri, A.3
  • 97
    • 84865333050 scopus 로고    scopus 로고
    • A phase 1/2 study of carfilzomib in combination with lenalidomide and low-dose dexamethasone as a frontline treatment for multiple myeloma
    • A.J. Jakubowiak, D. Dytfeld, and K.A. Griffith A phase 1/2 study of carfilzomib in combination with lenalidomide and low-dose dexamethasone as a frontline treatment for multiple myeloma Blood 120 2012 1801 1809
    • (2012) Blood , vol.120 , pp. 1801-1809
    • Jakubowiak, A.J.1    Dytfeld, D.2    Griffith, K.A.3
  • 98
    • 67650882695 scopus 로고    scopus 로고
    • Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: High response rates in a phase II clinical trial
    • C.B. Reeder, D.E. Reece, and V. Kukreti Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial Leukemia 23 2009 1337 1341
    • (2009) Leukemia , vol.23 , pp. 1337-1341
    • Reeder, C.B.1    Reece, D.E.2    Kukreti, V.3
  • 99
    • 77954618168 scopus 로고    scopus 로고
    • Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
    • P.G. Richardson, E. Weller, and S. Lonial Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma Blood 116 2010 679 686
    • (2010) Blood , vol.116 , pp. 679-686
    • Richardson, P.G.1    Weller, E.2    Lonial, S.3
  • 100
    • 84860709392 scopus 로고    scopus 로고
    • Lenalidomide maintenance after stem-cell transplantation for multiple myeloma
    • M. Attal, V. Lauwers-Cances, and G. Marit Lenalidomide maintenance after stem-cell transplantation for multiple myeloma N Engl J Med 366 2012 1782 1791
    • (2012) N Engl J Med , vol.366 , pp. 1782-1791
    • Attal, M.1    Lauwers-Cances, V.2    Marit, G.3
  • 101
    • 84860741191 scopus 로고    scopus 로고
    • Lenalidomide after stem-cell transplantation for multiple myeloma
    • P.L. McCarthy, K. Owzar, and C.C. Hofmeister Lenalidomide after stem-cell transplantation for multiple myeloma N Engl J Med 366 2012 1770 1781
    • (2012) N Engl J Med , vol.366 , pp. 1770-1781
    • McCarthy, P.L.1    Owzar, K.2    Hofmeister, C.C.3
  • 102
    • 70350094381 scopus 로고    scopus 로고
    • International Myeloma Working Group guidelines for the management of multiple myeloma patients ineligible for standard high-dose chemotherapy with autologous stem cell transplantation
    • A. Palumbo, O. Sezer, and R. Kyle International Myeloma Working Group guidelines for the management of multiple myeloma patients ineligible for standard high-dose chemotherapy with autologous stem cell transplantation Leukemia 23 2009 1716 1730
    • (2009) Leukemia , vol.23 , pp. 1716-1730
    • Palumbo, A.1    Sezer, O.2    Kyle, R.3
  • 103
    • 84877072648 scopus 로고    scopus 로고
    • Lenalidomide, melphalan, and prednisone, followed by lenalidomide maintenance, improves health-related quality of life in newly diagnosed multiple myeloma patients aged 65 years or older: Results of a randomized phase III trial
    • M.A. Dimopoulos, M. Delforge, and R. Hajek Lenalidomide, melphalan, and prednisone, followed by lenalidomide maintenance, improves health-related quality of life in newly diagnosed multiple myeloma patients aged 65 years or older: results of a randomized phase III trial Haematologica 98 2013 784 788
    • (2013) Haematologica , vol.98 , pp. 784-788
    • Dimopoulos, M.A.1    Delforge, M.2    Hajek, R.3
  • 104
    • 84875218691 scopus 로고    scopus 로고
    • Lenalidomide-prednisone induction followed by lenalidomide-melphalan- prednisone consolidation and lenalidomide-prednisone maintenance in newly diagnosed elderly unfit myeloma patients
    • P. Falco, F. Cavallo, and A. Larocca Lenalidomide-prednisone induction followed by lenalidomide-melphalan-prednisone consolidation and lenalidomide-prednisone maintenance in newly diagnosed elderly unfit myeloma patients Leukemia 27 2013 695 701
    • (2013) Leukemia , vol.27 , pp. 695-701
    • Falco, P.1    Cavallo, F.2    Larocca, A.3
  • 105
    • 84862937267 scopus 로고    scopus 로고
    • The role of maintenance thalidomide therapy in multiple myeloma: MRC Myeloma IX results and meta-analysis
    • G.J. Morgan, W.M. Gregory, and F.E. Davies The role of maintenance thalidomide therapy in multiple myeloma: MRC Myeloma IX results and meta-analysis Blood 119 2012 7 15
    • (2012) Blood , vol.119 , pp. 7-15
    • Morgan, G.J.1    Gregory, W.M.2    Davies, F.E.3
  • 106
    • 59449099316 scopus 로고    scopus 로고
    • Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation
    • B. Paiva, M.B. Vidriales, and J. Cervero Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation Blood 112 2008 4017 4023
    • (2008) Blood , vol.112 , pp. 4017-4023
    • Paiva, B.1    Vidriales, M.B.2    Cervero, J.3
  • 107
    • 70449396836 scopus 로고    scopus 로고
    • Multiparameter flow cytometry quantification of bone marrow plasma cells at diagnosis provides more prognostic information than morphological assessment in myeloma patients
    • B. Paiva, M.B. Vidriales, and J.J. Perez Multiparameter flow cytometry quantification of bone marrow plasma cells at diagnosis provides more prognostic information than morphological assessment in myeloma patients Haematologica 94 2009 1599 1602
    • (2009) Haematologica , vol.94 , pp. 1599-1602
    • Paiva, B.1    Vidriales, M.B.2    Perez, J.J.3
  • 108
    • 73349127140 scopus 로고    scopus 로고
    • The persistence of immunophenotypically normal residual bone marrow plasma cells at diagnosis identifies a good prognostic subgroup of symptomatic multiple myeloma patients
    • B. Paiva, M.B. Vidriales, and G. Mateo The persistence of immunophenotypically normal residual bone marrow plasma cells at diagnosis identifies a good prognostic subgroup of symptomatic multiple myeloma patients Blood 114 2009 4369 4372
    • (2009) Blood , vol.114 , pp. 4369-4372
    • Paiva, B.1    Vidriales, M.B.2    Mateo, G.3
  • 109
    • 84856086596 scopus 로고    scopus 로고
    • High-risk cytogenetics and persistent minimal residual disease by multiparameter flow cytometry predict unsustained complete response after autologous stem cell transplantation in multiple myeloma
    • B. Paiva, N.C. Gutierrez, and L. Rosinol High-risk cytogenetics and persistent minimal residual disease by multiparameter flow cytometry predict unsustained complete response after autologous stem cell transplantation in multiple myeloma Blood 119 2012 687 691
    • (2012) Blood , vol.119 , pp. 687-691
    • Paiva, B.1    Gutierrez, N.C.2    Rosinol, L.3
  • 110
    • 84885663321 scopus 로고    scopus 로고
    • A multiparameter flow cytometry immunophenotypic algorithm for the identification of newly-diagnosed symptomatic myeloma with an MGUS-like signature and long-term disease control
    • [Epub ahead of print]
    • B. Paiva, M.B. Vidriales, and L. Rosinol A multiparameter flow cytometry immunophenotypic algorithm for the identification of newly-diagnosed symptomatic myeloma with an MGUS-like signature and long-term disease control Leukemia 2013 [Epub ahead of print]
    • (2013) Leukemia
    • Paiva, B.1    Vidriales, M.B.2    Rosinol, L.3
  • 111
    • 77951489934 scopus 로고    scopus 로고
    • Correlation between clinical outcome and disease kinetics by quantitative PCR in myeloma patients following post-transplant consolidation with bortezomib, thalidomide and dexamethasone
    • M. Ladetto, G. Pagliano, and S. Ferrero Correlation between clinical outcome and disease kinetics by quantitative PCR in myeloma patients following post-transplant consolidation with bortezomib, thalidomide and dexamethasone Blood (ASH Annual Meeting Abstracts) 114 2009 960
    • (2009) Blood (ASH Annual Meeting Abstracts) , vol.114 , pp. 960
    • Ladetto, M.1    Pagliano, G.2    Ferrero, S.3
  • 112
    • 77951625298 scopus 로고    scopus 로고
    • Major tumor shrinking and persistent molecular remissions after consolidation with bortezomib, thalidomide, and dexamethasone in patients with autografted myeloma
    • M. Ladetto, G. Pagliano, and S. Ferrero Major tumor shrinking and persistent molecular remissions after consolidation with bortezomib, thalidomide, and dexamethasone in patients with autografted myeloma J Clin Oncol 28 2010 2077 2084
    • (2010) J Clin Oncol , vol.28 , pp. 2077-2084
    • Ladetto, M.1    Pagliano, G.2    Ferrero, S.3
  • 113
    • 78650303860 scopus 로고    scopus 로고
    • Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: A randomised phase 3 study
    • M. Cavo, P. Tacchetti, and F. Patriarca Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study Lancet 376 2010 2075 2085
    • (2010) Lancet , vol.376 , pp. 2075-2085
    • Cavo, M.1    Tacchetti, P.2    Patriarca, F.3


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