-
1
-
-
5644267858
-
Randomized comparison of dexamethasone combined with melphalan versus melphalan with prednisone in the treatment of elderly patients with multiple myeloma
-
DOI 10.1111/j.1365-2141.2004.05186.x
-
Hernandez JM, Garcia-Sanz R, Golvano E, et al. Randomized comparison of dexamethasone combined with melphalan versus melphalan with prednisone in the treatment of elderly patients with multiple myeloma. Br J Haematol. 2004;127(2):159-164. (Pubitemid 39371808)
-
(2004)
British Journal of Haematology
, vol.127
, Issue.2
, pp. 159-164
-
-
Hernandez, J.M.1
Garcia-Sanz, R.2
Golvano, E.3
Blade, J.4
Fernandez-Calvo, J.5
Trujillo, J.6
Soler, J.A.7
Gardella, S.8
Carbonell, F.9
Mateo, G.10
San, M.J.F.11
-
2
-
-
32644438680
-
Dexamethasone-based regimens versus melphalan-prednisone for elderly multiple myeloma patients ineligible for high-dose therapy
-
DOI 10.1182/blood-2005-04-1588
-
Facon T, Mary JY, Pegourie B, et al. Dexamethasone-based regimens versus melphalan-prednisone for elderly multiple myeloma patients ineligible for high-dose therapy. Blood. 2006;107(4):1292-1298. (Pubitemid 43242361)
-
(2006)
Blood
, vol.107
, Issue.4
, pp. 1292-1298
-
-
Facon, T.1
Mary, J.-Y.2
Pegourie, B.3
Attal, M.4
Renaud, M.5
Sadoun, A.6
Voillat, L.7
Dorvaux, V.8
Hulin, C.9
Lepeu, G.10
Harousseau, J.-L.11
Eschard, J.-P.12
Ferrant, A.13
Blanc, M.14
Maloisel, F.15
Orfeuvre, H.16
Rossi, J.-F.17
Azais, I.18
Monconduit, M.19
Collet, P.20
Anglaret, B.21
Yakoub-Agha, I.22
Wetterwald, M.23
Eghbali, H.24
Vekemans, M.-C.25
Maisonneuve, H.26
Troncy, J.27
Grosbois, B.28
Doyen, C.29
Thyss, A.30
Jaubert, J.31
Casassus, P.32
Thielemans, B.33
Bataille, R.34
more..
-
3
-
-
0344076348
-
Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: An overview of 6,633 patients from 27 randomized trials
-
Myeloma Trialists' Collaborative Group
-
Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: an overview of 6,633 patients from 27 randomized trials. Myeloma Trialists' Collaborative Group. J Clin Oncol. 1998;16(12):3832-3842.
-
(1998)
J Clin Oncol
, vol.16
, Issue.12
, pp. 3832-3842
-
-
-
4
-
-
84859196307
-
IMWG consensus on maintenance therapy in multiple myeloma
-
Ludwig H, Durie BG, McCarthy P, et al. IMWG consensus on maintenance therapy in multiple myeloma. Blood. 2012;119(13):3003-3015.
-
(2012)
Blood
, vol.119
, Issue.13
, pp. 3003-3015
-
-
Ludwig, H.1
Durie, B.G.2
McCarthy, P.3
-
5
-
-
33644843725
-
Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: Randomised controlled trial
-
DOI 10.1016/S0140-6736(06)68338-4, PII S0140673606683384
-
Palumbo A, Bringhen S, Caravita T, et al. Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial. Lancet. 2006;367(9513):825-831. (Pubitemid 43363369)
-
(2006)
Lancet
, vol.367
, Issue.9513
, pp. 825-831
-
-
Palumbo, A.1
Bringhen, S.2
Caravita, T.3
Merla, E.4
Capparella, V.5
Callea, V.6
Cangialosi, C.7
Grasso, M.8
Rossini, F.9
Galli, M.10
Catalano, L.11
Zamagni, E.12
Petrucci, M.T.13
De Stefano, V.14
Ceccarelli, M.15
Ambrosini, M.T.16
Avonto, I.17
Falco, P.18
Ciccone, G.19
Liberati, A.M.20
Musto, P.21
Boccadoro, M.22
more..
-
6
-
-
34848833957
-
Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): A randomised trial
-
DOI 10.1016/S0140-6736(07)61537-2, PII S0140673607615372
-
Facon T, Mary JY, Hulin C, et al. Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial. Lancet. 2007;370(9594):1209-1218. (Pubitemid 47516593)
-
(2007)
Lancet
, vol.370
, Issue.9594
, pp. 1209-1218
-
-
Facon, T.1
Mary, J.Y.2
Hulin, C.3
Benboubker, L.4
Attal, M.5
Pegourie, B.6
Renaud, M.7
Harousseau, J.L.8
Guillerm, G.9
Chaleteix, C.10
Dib, M.11
Voillat, L.12
Maisonneuve, H.13
Troncy, J.14
Dorvaux, V.15
Monconduit, M.16
Martin, C.17
Casassus, P.18
Jaubert, J.19
Jardel, H.20
Doyen, C.21
Kolb, B.22
Anglaret, B.23
Grosbois, B.24
Yakoub-Agha, I.25
Mathiot, C.26
Avet-Loiseau, H.27
more..
-
7
-
-
68949137225
-
Efficacy of melphalan and prednisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma: IFM 01/01 trial
-
Hulin C, Facon T, Rodon P, et al. Efficacy of melphalan and prednisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma: IFM 01/01 trial. J Clin Oncol. 2009;27(22):3664-3670.
-
(2009)
J Clin Oncol
, vol.27
, Issue.22
, pp. 3664-3670
-
-
Hulin, C.1
Facon, T.2
Rodon, P.3
-
8
-
-
77955495783
-
Phase III study of the value of thalidomide added to melphalan plus prednisone in elderly patients with newly diagnosed multiple myeloma: The HOVON 49 Study
-
Wijermans P, Schaafsma M, Termorshuizen F, et al. Phase III study of the value of thalidomide added to melphalan plus prednisone in elderly patients with newly diagnosed multiple myeloma: the HOVON 49 Study. J Clin Oncol. 2010;28(19):3160-3166.
-
(2010)
J Clin Oncol
, vol.28
, Issue.19
, pp. 3160-3166
-
-
Wijermans, P.1
Schaafsma, M.2
Termorshuizen, F.3
-
9
-
-
77956599686
-
Melphalan and prednisone plus thalidomide or placebo in elderly patients with multiple myeloma
-
Waage A, Gimsing P, Fayers P, et al. Melphalan and prednisone plus thalidomide or placebo in elderly patients with multiple myeloma. Blood. 2010;116(9):1405-1412.
-
(2010)
Blood
, vol.116
, Issue.9
, pp. 1405-1412
-
-
Waage, A.1
Gimsing, P.2
Fayers, P.3
-
10
-
-
78650159700
-
Addition of thalidomide to oral melphalan/prednisone in patients with multiple myeloma not eligible for transplantation: Results of a randomized trial from the Turkish Myeloma Study Group
-
Beksac M, Haznedar R, Firatli-Tuglular T, et al. Addition of thalidomide to oral melphalan/prednisone in patients with multiple myeloma not eligible for transplantation: results of a randomized trial from the Turkish Myeloma Study Group. Eur J Haematol. 2011;86(1):16-22.
-
(2011)
Eur J Haematol
, vol.86
, Issue.1
, pp. 16-22
-
-
Beksac, M.1
Haznedar, R.2
Firatli-Tuglular, T.3
-
11
-
-
65349142006
-
Thalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma
-
Ludwig H, Hajek R, Tothova E, et al. Thalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma. Blood. 2009;113(15):3435-3442.
-
(2009)
Blood
, vol.113
, Issue.15
, pp. 3435-3442
-
-
Ludwig, H.1
Hajek, R.2
Tothova, E.3
-
12
-
-
84862937267
-
The role of maintenance thalidomide therapy in multiple myeloma: MRC Myeloma IX results and meta-analysis
-
Morgan GJ, Gregory WM, Davies FE, et al. The role of maintenance thalidomide therapy in multiple myeloma: MRC Myeloma IX results and meta-analysis. Blood. 2012;119(1):7-15.
-
(2012)
Blood
, vol.119
, Issue.1
, pp. 7-15
-
-
Morgan, G.J.1
Gregory, W.M.2
Davies, F.E.3
-
13
-
-
79957447588
-
A phase 3 study evaluating the efficacy and safety of lenalidomide combined with melphalan and prednisone in patients > = 65 years with newly diagnosed multiple myeloma (NDMM): Continuous use of lenalidomide vs fixed-duration regimens
-
abstract Abstract 622
-
Palumbo A, Delforge M, Catalano J, et al. A phase 3 study evaluating the efficacy and safety of lenalidomide combined with melphalan and prednisone in patients > = 65 years with newly diagnosed multiple myeloma (NDMM): continuous use of lenalidomide vs fixed-duration regimens [abstract]. Blood (ASH Annual Meeting Abstracts). 2010;116(21):Abstract 622.
-
(2010)
Blood (ASH Annual Meeting Abstracts)
, vol.116
, Issue.21
-
-
Palumbo, A.1
Delforge, M.2
Catalano, J.3
-
14
-
-
78650993336
-
Bortezomib-melphalan-prednisone-thalidomide followed by maintenance with bortezomib-thalidomide compared with bortezomib-melphalan-prednisone for initial treatment of multiple myeloma: A randomized controlled trial
-
Palumbo A, Bringhen S, Rossi D, et al. Bortezomib-melphalan-prednisone- thalidomide followed by maintenance with bortezomib-thalidomide compared with bortezomib-melphalan-prednisone for initial treatment of multiple myeloma: a randomized controlled trial. J Clin Oncol. 2010;28(34):5101-5109.
-
(2010)
J Clin Oncol
, vol.28
, Issue.34
, pp. 5101-5109
-
-
Palumbo, A.1
Bringhen, S.2
Rossi, D.3
-
15
-
-
84862696861
-
Efficacy and safety of three bortezomib-based combinations in elderly, newly diagnosed multiple myeloma patients: Results from all randomized patients in the community-based, phase 3b UPFRONT study
-
abstract Abstract 478
-
Niesvizky R, Flinn IW, Rifkin R, et al. Efficacy and safety of three bortezomib-based combinations in elderly, newly diagnosed multiple myeloma patients: results from all randomized patients in the community-based, phase 3b UPFRONT study [abstract]. Blood (ASH Annual Meeting Abstracts). 2011;118(21):Abstract 478.
-
(2011)
Blood (ASH Annual Meeting Abstracts)
, vol.118
, Issue.21
-
-
Niesvizky, R.1
Flinn, I.W.2
Rifkin, R.3
-
16
-
-
77957344540
-
Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma: A randomised trial
-
Mateos MV, Oriol A, Martinez-Lopez J, et al. Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma: a randomised trial. Lancet Oncol. 2010;11(10):934-941.
-
(2010)
Lancet Oncol
, vol.11
, Issue.10
, pp. 934-941
-
-
Mateos, M.V.1
Oriol, A.2
Martinez-Lopez, J.3
-
17
-
-
33845546906
-
Prognostic and biological implications of genetic abnormalities in multiple myeloma undergoing autologous stem cell transplantation: t(4;14) is the most relevant adverse prognostic factor, whereas RB deletion as a unique abnormality is not associated with adverse prognosis
-
DOI 10.1038/sj.leu.2404413, PII 2404413
-
Gutierrez NC, Castellanos MV, Martin ML, et al. Prognostic and biological implications of genetic abnormalities in multiple myeloma undergoing autologous stem cell transplantation: t(4;14) is the most relevant adverse prognostic factor, whereas RB deletion as a unique abnormality is not associated with adverse prognosis. Leukemia. 2007;21(1):143-150. (Pubitemid 44921845)
-
(2007)
Leukemia
, vol.21
, Issue.1
, pp. 143-150
-
-
Gutierrez, N.C.1
Castellanos, M.V.2
Martin, M.L.3
Mateos, M.V.4
Hernandez, J.M.5
Fernandez, M.6
Carrera, D.7
Rosinol, L.8
Ribera, J.M.9
Ojanguren, J.M.10
Palomera, L.11
Gardella, S.12
Escoda, L.13
Hernandez-Boluda, J.C.14
Bello, J.L.15
De La, R.J.16
Lahuerta, J.J.17
San, M.J.F.18
-
18
-
-
79953322412
-
The progression from MGUS to smoldering myeloma and eventually to multiple myeloma involves a clonal expansion of genetically abnormal plasma cells
-
Lopez-Corral L, Gutierrez NC, Vidriales MB, et al. The progression from MGUS to smoldering myeloma and eventually to multiple myeloma involves a clonal expansion of genetically abnormal plasma cells. Clin Cancer Res. 2011;17(7):1692-1700.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.7
, pp. 1692-1700
-
-
Lopez-Corral, L.1
Gutierrez, N.C.2
Vidriales, M.B.3
-
19
-
-
18244428600
-
Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation
-
DOI 10.1046/j.1365-2141.1998.00930.x
-
Blade J, Samson D, Reece D, et al. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant. Br J Haematol. 1998;102(5):1115-1123. (Pubitemid 28435189)
-
(1998)
British Journal of Haematology
, vol.102
, Issue.5
, pp. 1115-1123
-
-
Blade, J.1
Samson, D.2
Reece, D.3
Apperley, J.4
Bjorkstrand, B.5
Gahrton, G.6
Gertz, M.7
Giralt, S.8
Jagannath, S.9
Vesole, D.10
-
20
-
-
79952790841
-
HOVON-65/GMMG-HD4 randomized phase III trial comparing bortezomib, doxorubicin, dexamethasone (PAD) vs VAD followed by high-dose melphalan (HDM) and maintenance with bortezomib or thalidomide in patients with newly diagnosed multiple myeloma (MM)
-
abstract Abstract 40
-
Sonneveld P, Schmidt-Wolf I, van der Holt B, et al. HOVON-65/GMMG-HD4 randomized phase III trial comparing bortezomib, doxorubicin, dexamethasone (PAD) vs VAD followed by high-dose melphalan (HDM) and maintenance with bortezomib or thalidomide in patients with newly diagnosed multiple myeloma (MM) [abstract]. Blood (ASH Annual Meeting Abstracts). 2010;116(21):Abstract 40.
-
(2010)
Blood (ASH Annual Meeting Abstracts)
, vol.116
, Issue.21
-
-
Sonneveld, P.1
Schmidt-Wolf, I.2
Van Der Holt, B.3
-
21
-
-
64649083365
-
Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedure
-
Spencer A, Prince HM, Roberts AW, et al. Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedure. J Clin Oncol. 2009;27(11):1788-1793.
-
(2009)
J Clin Oncol
, vol.27
, Issue.11
, pp. 1788-1793
-
-
Spencer, A.1
Prince, H.M.2
Roberts, A.W.3
-
22
-
-
77956829463
-
Thalidomide maintenance treatment increases progression-free but not overall survival in elderly patients with myeloma
-
Ludwig H, Adam Z, Tothova E, et al. Thalidomide maintenance treatment increases progression-free but not overall survival in elderly patients with myeloma. Haematologica. 2010;95(9):1548-1554.
-
(2010)
Haematologica
, vol.95
, Issue.9
, pp. 1548-1554
-
-
Ludwig, H.1
Adam, Z.2
Tothova, E.3
-
23
-
-
79953078844
-
Complete response correlates with long-term progression-free and overall survival in elderly myeloma treated with novel agents: Analysis of 1175 patients
-
Gay F, Larocca A, Wijermans P, et al. Complete response correlates with long-term progression-free and overall survival in elderly myeloma treated with novel agents: analysis of 1175 patients. Blood. 2011;117(11):3025-3130.
-
(2011)
Blood
, vol.117
, Issue.11
, pp. 3025-3130
-
-
Gay, F.1
Larocca, A.2
Wijermans, P.3
-
24
-
-
80051570906
-
Thalidomide for previously untreated elderly patients with multiple myeloma: Meta-analysis of 1685 individual patient data from 6 randomized clinical trials
-
Fayers PM, Palumbo A, Hulin C, et al. Thalidomide for previously untreated elderly patients with multiple myeloma: meta-analysis of 1685 individual patient data from 6 randomized clinical trials. Blood. 2011;118(5):1239-1247.
-
(2011)
Blood
, vol.118
, Issue.5
, pp. 1239-1247
-
-
Fayers, P.M.1
Palumbo, A.2
Hulin, C.3
-
25
-
-
84858791957
-
Continued overall survival benefit after 5 years' follow-up with bortezomib-melphalan-prednisone (VMP) versus melphalan-prednisone (MP) in patients with previously untreated multiple myeloma, and no increased risk of second primary malignancies: Final results of the phase 3 VISTA trial
-
abstract Abstract 476
-
Miguel JFS, Schlag R, Khuageva NK, et al. Continued overall survival benefit after 5 years' follow-up with bortezomib-melphalan-prednisone (VMP) versus melphalan-prednisone (MP) in patients with previously untreated multiple myeloma, and no increased risk of second primary malignancies: final results of the phase 3 VISTA trial [abstract]. Blood (ASH Annual Meeting Abstracts). 2011;118(21):Abstract 476.
-
(2011)
Blood (ASH Annual Meeting Abstracts)
, vol.118
, Issue.21
-
-
Miguel, J.F.S.1
Schlag, R.2
Khuageva, N.K.3
|