-
1
-
-
0037374498
-
The price of innovation: New estimates of drug development costs
-
DOI 10.1016/S0167-6296(02)00126-1
-
J.A. DiMasi, R.W. Hansen, and H.G. Grabowski The price of innovation: new estimates of drug development costs J Health Econ 22 2003 151 185 (Pubitemid 36279392)
-
(2003)
Journal of Health Economics
, vol.22
, Issue.2
, pp. 151-185
-
-
DiMasi, J.A.1
Hansen, R.W.2
Grabowski, H.G.3
-
2
-
-
79952132207
-
Development of ST-246(R) for treatment of poxvirus infections
-
R. Jordan, J.M. Leeds, S. Tyavanagimatt, and D.E. Hruby Development of ST-246(R) for treatment of poxvirus infections Viruses 2 2010 2409 2435
-
(2010)
Viruses
, vol.2
, pp. 2409-2435
-
-
Jordan, R.1
Leeds, J.M.2
Tyavanagimatt, S.3
Hruby, D.E.4
-
3
-
-
79957582537
-
Development of the small-molecule antiviral ST-246 as a smallpox therapeutic
-
D.W. Grosenbach, R. Jordan, and D.E. Hruby Development of the small-molecule antiviral ST-246 as a smallpox therapeutic Future Virol 6 2011 653 671
-
(2011)
Future Virol
, vol.6
, pp. 653-671
-
-
Grosenbach, D.W.1
Jordan, R.2
Hruby, D.E.3
-
4
-
-
26444587116
-
An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus challenge
-
DOI 10.1128/JVI.79.20.13139-13149.2005
-
G. Yang, D.C. Pevear, M.H. Davies, M.S. Collett, T. Bailey, S. Rippen, L. Barone, C. Burns, G. Rhodes, and S. Tohan An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus challenge J Virol 79 2005 13139 13149 (Pubitemid 41433232)
-
(2005)
Journal of Virology
, vol.79
, Issue.20
, pp. 13139-13149
-
-
Yang, G.1
Pevear, D.C.2
Davies, M.H.3
Collett, M.S.4
Bailey, T.5
Rippen, S.6
Barone, L.7
Burns, C.8
Rhodes, G.9
Tohan, S.10
Huggins, J.W.11
Baker, R.O.12
Buller, R.L.M.13
Touchette, E.14
Waller, K.15
Schriewer, J.16
Neyts, J.17
DeClercq, E.18
Jones, K.19
Hruby, D.20
Jordan, R.21
more..
-
5
-
-
71249115159
-
ST-246 inhibits in vivo poxvirus dissemination, virus shedding, and systemic disease manifestation
-
A. Berhanu, D.S. King, S. Mosier, R. Jordan, K.F. Jones, D.E. Hruby, and D.W. Grosenbach ST-246 inhibits in vivo poxvirus dissemination, virus shedding, and systemic disease manifestation Antimicrob Agents Chemother 53 2009 4999 5009
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 4999-5009
-
-
Berhanu, A.1
King, D.S.2
Mosier, S.3
Jordan, R.4
Jones, K.F.5
Hruby, D.E.6
Grosenbach, D.W.7
-
6
-
-
34249742507
-
Efficacy of the antipoxvirus compound ST-246 for treatment of severe orthopoxvirus infection
-
E. Sbrana, R. Jordan, D.E. Hruby, R.I. Mateo, S.Y. Xiao, M. Siirin, P.C. Newman, A.P. DAR, and R.B. Tesh Efficacy of the antipoxvirus compound ST-246 for treatment of severe orthopoxvirus infection Am J Trop Med Hyg 76 2007 768 773 (Pubitemid 351627722)
-
(2007)
American Journal of Tropical Medicine and Hygiene
, vol.76
, Issue.4
, pp. 768-773
-
-
Sbrana, E.1
Jordan, R.2
Hruby, D.E.3
Mateo, R.I.4
Xiao, S.-Y.5
Siirin, M.6
Newman, P.C.7
Travassos Da Rosa, A.P.A.8
Tesh, R.B.9
-
7
-
-
56249107823
-
Successful treatment in the monkeypox and variola primate models of smallpox by the oral drug ST-246
-
J. Huggins, A. Goff, M. Eric, N. Twenhafel, J. Chapman, M. Tate, R. Jordan, T. Bolken, and D. Hruby Successful treatment in the monkeypox and variola primate models of smallpox by the oral drug ST-246 Antiviral Res 74 2007 A35
-
(2007)
Antiviral Res
, vol.74
, pp. 35
-
-
Huggins, J.1
Goff, A.2
Eric, M.3
Twenhafel, N.4
Chapman, J.5
Tate, M.6
Jordan, R.7
Bolken, T.8
Hruby, D.9
-
8
-
-
80052279730
-
Effective antiviral treatment of systemic orthopoxvirus disease: ST-246 treatment of prairie dogs infected with monkeypox virus
-
S.K. Smith, J. Self, S. Weiss, D. Carroll, Z. Braden, R.L. Regnery, W. Davidson, R. Jordan, D.E. Hruby, and I.K. Damon Effective antiviral treatment of systemic orthopoxvirus disease: ST-246 treatment of prairie dogs infected with monkeypox virus J Virol 85 2011 9176 9187
-
(2011)
J Virol
, vol.85
, pp. 9176-9187
-
-
Smith, S.K.1
Self, J.2
Weiss, S.3
Carroll, D.4
Braden, Z.5
Regnery, R.L.6
Davidson, W.7
Jordan, R.8
Hruby, D.E.9
Damon, I.K.10
-
9
-
-
76249114760
-
Efficacy of ST-246 versus lethal poxvirus challenge in immunodeficient mice
-
D.W. Grosenbach, A. Berhanu, D.S. King, S. Mosier, K.F. Jones, R.A. Jordan, T.C. Bolken, and D.E. Hruby Efficacy of ST-246 versus lethal poxvirus challenge in immunodeficient mice Proc Natl Acad Sci U S A 107 2010 838 843
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 838-843
-
-
Grosenbach, D.W.1
Berhanu, A.2
King, D.S.3
Mosier, S.4
Jones, K.F.5
Jordan, R.A.6
Bolken, T.C.7
Hruby, D.E.8
-
10
-
-
67049136160
-
Nonhuman primates are protected from smallpox virus or monkeypox virus challenges by the antiviral drug ST-246
-
J. Huggins, A. Goff, L. Hensley, E. Mucker, J. Shamblin, C. Wlazlowski, W. Johnson, J. Chapman, T. Larsen, and N. Twenhafel Nonhuman primates are protected from smallpox virus or monkeypox virus challenges by the antiviral drug ST-246 Antimicrob Agents Chemother 53 2009 2620 2625
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 2620-2625
-
-
Huggins, J.1
Goff, A.2
Hensley, L.3
Mucker, E.4
Shamblin, J.5
Wlazlowski, C.6
Johnson, W.7
Chapman, J.8
Larsen, T.9
Twenhafel, N.10
-
11
-
-
42949107447
-
Single-dose safety and pharmacokinetics of ST-246, a novel orthopoxvirus egress inhibitor
-
DOI 10.1128/AAC.01303-07
-
R. Jordan, D. Tien, T.C. Bolken, K.F. Jones, S.R. Tyavanagimatt, J. Strasser, A. Frimm, M.L. Corrado, P.G. Strome, and D.E. Hruby Single-dose safety and pharmacokinetics of ST-246, a novel orthopoxvirus egress inhibitor Antimicrob Agents Chemother 52 2008 1721 1727 (Pubitemid 351614665)
-
(2008)
Antimicrobial Agents and Chemotherapy
, vol.52
, Issue.5
, pp. 1721-1727
-
-
Jordan, R.1
Tien, D.2
Bolken, T.C.3
Jones, K.F.4
Tyavanagimatt, S.R.5
Strasser, J.6
Frimm, A.7
Corrado, M.L.8
Strome, P.G.9
Hruby, D.E.10
-
12
-
-
84865404323
-
Safety and pharmacokinetics of the anti-orthopoxvirus compound ST-246 following a single daily oral dose for 14 days in human volunteers
-
J. Chinsangaram, K.M. Honeychurch, S.R. Tyavanagimatt, J.M. Leeds, T.C. Bolken, K.F. Jones, R. Jordan, T. Marbury, J. Ruckle, and D. Mee-Lee Safety and pharmacokinetics of the anti-orthopoxvirus compound ST-246 following a single daily oral dose for 14 days in human volunteers Antimicrob Agents Chemother 56 2012 4900 4905
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 4900-4905
-
-
Chinsangaram, J.1
Honeychurch, K.M.2
Tyavanagimatt, S.R.3
Leeds, J.M.4
Bolken, T.C.5
Jones, K.F.6
Jordan, R.7
Marbury, T.8
Ruckle, J.9
Mee-Lee, D.10
-
13
-
-
84862548012
-
Pharmacokinetic comparison of a single oral dose of polymorph form i versus form v capsules of the antiorthopoxvirus compound ST-246 in human volunteers
-
J. Chinsangaram, K.M. Honeychurch, S.R. Tyavanagimatt, T.C. Bolken, R. Jordan, K.F. Jones, T. Marbury, I. Lichtenstein, M. Pickens, and M. Corrado Pharmacokinetic comparison of a single oral dose of polymorph form I versus form V capsules of the antiorthopoxvirus compound ST-246 in human volunteers Antimicrob Agents Chemother 56 2012 3582 3586
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 3582-3586
-
-
Chinsangaram, J.1
Honeychurch, K.M.2
Tyavanagimatt, S.R.3
Bolken, T.C.4
Jordan, R.5
Jones, K.F.6
Marbury, T.7
Lichtenstein, I.8
Pickens, M.9
Corrado, M.10
-
14
-
-
77952642017
-
Safety and pharmacokinetics of the antiorthopoxvirus compound ST-246 following repeat oral dosing in healthy adult subjects
-
R. Jordan, J. Chinsangaram, T.C. Bolken, S.R. Tyavanagimatt, D. Tien, K.F. Jones, A. Frimm, M.L. Corrado, M. Pickens, and P. Landis Safety and pharmacokinetics of the antiorthopoxvirus compound ST-246 following repeat oral dosing in healthy adult subjects Antimicrob Agents Chemother 54 2010 2560 2566
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2560-2566
-
-
Jordan, R.1
Chinsangaram, J.2
Bolken, T.C.3
Tyavanagimatt, S.R.4
Tien, D.5
Jones, K.F.6
Frimm, A.7
Corrado, M.L.8
Pickens, M.9
Landis, P.10
-
15
-
-
35848968505
-
Synergistic efficacy of the combination of ST-246 with CMX001 against orthopoxviruses
-
DOI 10.1128/AAC.00762-07
-
D.C. Quenelle, M.N. Prichard, K.A. Keith, D.E. Hruby, R. Jordan, G.R. Painter, A. Robertson, and E.R. Kern Synergistic efficacy of the combination of ST-246 with CMX001 against orthopoxviruses Antimicrob Agents Chemother 51 2007 4118 4124 (Pubitemid 350057813)
-
(2007)
Antimicrobial Agents and Chemotherapy
, vol.51
, Issue.11
, pp. 4118-4124
-
-
Quenelle, D.C.1
Prichard, M.N.2
Keith, K.A.3
Hruby, D.E.4
Jordan, R.5
Painter, G.R.6
Robertson, A.7
Kern, E.R.8
-
16
-
-
43249105781
-
Severe eczema vaccinatum in a household contact of a smallpox vaccinee
-
DOI 10.1086/587668
-
S. Vora, I. Damon, V. Fulginiti, S.G. Weber, M. Kahana, S.L. Stein, S.I. Gerber, S. Garcia-Houchins, E. Lederman, and D. Hruby Severe eczema vaccinatum in a household contact of a smallpox vaccinee Clin Infect Dis 46 2008 1555 1561 (Pubitemid 351706737)
-
(2008)
Clinical Infectious Diseases
, vol.46
, Issue.10
, pp. 1555-1561
-
-
Vora, S.1
Damon, I.2
Fulginiti, V.3
Weber, S.G.4
Kahana, M.5
Stein, S.L.6
Gerber, S.I.7
Garcia-Houchins, S.8
Lederman, E.9
Hruby, D.10
Collins, L.11
Scott, D.12
Thompson, K.13
Barson, J.V.14
Regnery, R.15
Hughes, C.16
Daum, R.S.17
Li, Y.18
Zhao, H.19
Smith, S.20
Braden, Z.21
Karem, K.22
Olson, V.23
Davidson, W.24
Trindade, G.25
Bolken, T.26
Jordan, R.27
Tien, D.28
Marcinak, J.29
more..
-
17
-
-
84867543892
-
Progressive vaccinia: Case description and laboratory-guided therapy with vaccinia immune globulin, ST-246, and CMX001
-
E.R. Lederman, W. Davidson, H.L. Groff, S.K. Smith, T. Warkentien, Y. Li, K.A. Wilkins, K.L. Karem, R.S. Akondy, and R. Ahmed Progressive vaccinia: case description and laboratory-guided therapy with vaccinia immune globulin, ST-246, and CMX001 J Infect Dis 206 2012 1372 1385
-
(2012)
J Infect Dis
, vol.206
, pp. 1372-1385
-
-
Lederman, E.R.1
Davidson, W.2
Groff, H.L.3
Smith, S.K.4
Warkentien, T.5
Li, Y.6
Wilkins, K.A.7
Karem, K.L.8
Akondy, R.S.9
Ahmed, R.10
-
18
-
-
34249711851
-
Dramatic rescue relieves rare case of smallpox infection
-
DOI 10.1038/nm0507-517, PII NM0507517
-
E. Marris Dramatic rescue relieves rare case of smallpox infection Nat Med 13 2007 517 (Pubitemid 46828462)
-
(2007)
Nature Medicine
, vol.13
, Issue.5
, pp. 517
-
-
Marris, E.1
-
19
-
-
57649167118
-
Eczema vaccinatum resulting from the transmission of vaccinia virus from a smallpox vaccinee: An investigation of potential fomites in the home environment
-
E. Lederman, R. Miramontes, J. Openshaw, V.A. Olson, K.L. Karem, J. Marcinak, R. Panares, W. Staggs, D. Allen, and S.G. Weber Eczema vaccinatum resulting from the transmission of vaccinia virus from a smallpox vaccinee: an investigation of potential fomites in the home environment Vaccine 27 2009 375 377
-
(2009)
Vaccine
, vol.27
, pp. 375-377
-
-
Lederman, E.1
Miramontes, R.2
Openshaw, J.3
Olson, V.A.4
Karem, K.L.5
Marcinak, J.6
Panares, R.7
Staggs, W.8
Allen, D.9
Weber, S.G.10
-
20
-
-
0022630892
-
Lassa fever: Effective therapy with ribavirin
-
J.B. McCormick, I.J. King, P.A. Webb, C.L. Scribner, R.B. Craven, K.M. Johnson, L.H. Elliott, and R. Belmont-Williams Lassa fever. Effective therapy with ribavirin N Engl J Med 314 1986 20 26 (Pubitemid 16183064)
-
(1986)
New England Journal of Medicine
, vol.314
, Issue.1
, pp. 20-26
-
-
McCormick, J.B.1
King, I.J.2
Webb, P.A.3
-
21
-
-
84872354376
-
Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole and related heterocycles
-
J.R. Burgeson, A.L. Moore, D.N. Gharaibeh, R.A. Larson, N.R. Cerruti, S.M. Amberg, D.E. Hruby, and D. Dai Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole and related heterocycles Bioorg Med Chem Lett 23 2013 750 756
-
(2013)
Bioorg Med Chem Lett
, vol.23
, pp. 750-756
-
-
Burgeson, J.R.1
Moore, A.L.2
Gharaibeh, D.N.3
Larson, R.A.4
Cerruti, N.R.5
Amberg, S.M.6
Hruby, D.E.7
Dai, D.8
-
22
-
-
84872279263
-
Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole
-
D. Dai, J.R. Burgeson, D.N. Gharaibeh, A.L. Moore, R.A. Larson, N.R. Cerruti, S.M. Amberg, T.C. Bolken, and D.E. Hruby Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole Bioorg Med Chem Lett 23 2013 744 749
-
(2013)
Bioorg Med Chem Lett
, vol.23
, pp. 744-749
-
-
Dai, D.1
Burgeson, J.R.2
Gharaibeh, D.N.3
Moore, A.L.4
Larson, R.A.5
Cerruti, N.R.6
Amberg, S.M.7
Bolken, T.C.8
Hruby, D.E.9
-
23
-
-
79953678352
-
Evaluation of Lassa antiviral compound ST-193 in a guinea pig model
-
K.A. Cashman, M.A. Smith, N.A. Twenhafel, R.A. Larson, K.F. Jones, R.D. Allen 3rd, D. Dai, J. Chinsangaram, T.C. Bolken, and D.E. Hruby Evaluation of Lassa antiviral compound ST-193 in a guinea pig model Antiviral Res 90 2011 70 79
-
(2011)
Antiviral Res
, vol.90
, pp. 70-79
-
-
Cashman, K.A.1
Smith, M.A.2
Twenhafel, N.A.3
Larson, R.A.4
Jones, K.F.5
Allen III, R.D.6
Dai, D.7
Chinsangaram, J.8
Bolken, T.C.9
Hruby, D.E.10
-
24
-
-
80052855889
-
Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors
-
B.W. Neuman, L.H. Bederka, D.A. Stein, J.P. Ting, H.M. Moulton, and M.J. Buchmeier Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors Antimicrob Agents Chemother 55 2011 4631 4638
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 4631-4638
-
-
Neuman, B.W.1
Bederka, L.H.2
Stein, D.A.3
Ting, J.P.4
Moulton, H.M.5
Buchmeier, M.J.6
-
25
-
-
35948957769
-
In vitro and in vivo activities of T-705 against arenavirus and bunyavirus infections
-
DOI 10.1128/AAC.00356-07
-
B.B. Gowen, M.H. Wong, K.H. Jung, A.B. Sanders, M. Mendenhall, K.W. Bailey, Y. Furuta, and R.W. Sidwell In vitro and in vivo activities of T-705 against arenavirus and bunyavirus infections Antimicrob Agents Chemother 51 2007 3168 3176 (Pubitemid 350067524)
-
(2007)
Antimicrobial Agents and Chemotherapy
, vol.51
, Issue.9
, pp. 3168-3176
-
-
Gowen, B.B.1
Wong, M.-H.2
Jung, K.-H.3
Sanders, A.B.4
Mendenhall, M.5
Bailey, K.W.6
Furuta, Y.7
Sidwell, R.W.8
-
26
-
-
57149094212
-
Experience with intravenous ribavirin in the treatment of hemorrhagic fever with renal syndrome in Korea
-
J.M. Rusnak, W.R. Byrne, K.N. Chung, P.H. Gibbs, T.T. Kim, E.F. Boudreau, T. Cosgriff, P. Pittman, K.Y. Kim, and M.S. Erlichman Experience with intravenous ribavirin in the treatment of hemorrhagic fever with renal syndrome in Korea Antiviral Res 81 2009 68 76
-
(2009)
Antiviral Res
, vol.81
, pp. 68-76
-
-
Rusnak, J.M.1
Byrne, W.R.2
Chung, K.N.3
Gibbs, P.H.4
Kim, T.T.5
Boudreau, E.F.6
Cosgriff, T.7
Pittman, P.8
Kim, K.Y.9
Erlichman, M.S.10
-
27
-
-
7644244053
-
Placebo-controlled, double-blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America
-
DOI 10.1086/425007
-
G.J. Mertz, L. Miedzinski, D. Goade, A.T. Pavia, B. Hjelle, C.O. Hansbarger, H. Levy, F.T. Koster, K. Baum, and A. Lindemulder Placebo-controlled, double-blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America Clin Infect Dis 39 2004 1307 1313 (Pubitemid 39458516)
-
(2004)
Clinical Infectious Diseases
, vol.39
, Issue.9
, pp. 1307-1313
-
-
Mertz, G.J.1
Miedzinski, L.2
Goade, D.3
Pavia, A.T.4
Hjelle, B.5
Hansbarger, C.O.6
Levy, H.7
Koster, F.T.8
Baum, K.9
Lindemulder, A.10
Wang, W.11
Riser, L.12
Fernandez, H.13
Whitley, R.J.14
-
28
-
-
43149119012
-
Synthesis of 1-beta-d-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus
-
D.H. Chung, S.C. Kumarapperuma, Y. Sun, Q. Li, Y.K. Chu, J.B. Arterburn, W.B. Parker, J. Smith, K. Spik, and H.N. Ramanathan Synthesis of 1-beta-d-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus Antiviral Res 79 2008 19 27
-
(2008)
Antiviral Res
, vol.79
, pp. 19-27
-
-
Chung, D.H.1
Kumarapperuma, S.C.2
Sun, Y.3
Li, Q.4
Chu, Y.K.5
Arterburn, J.B.6
Parker, W.B.7
Smith, J.8
Spik, K.9
Ramanathan, H.N.10
-
29
-
-
77649246144
-
A broad-spectrum antiviral targeting entry of enveloped viruses
-
M.C. Wolf, A.N. Freiberg, T. Zhang, Z. Akyol-Ataman, A. Grock, P.W. Hong, J. Li, N.F. Watson, A.Q. Fang, and H.C. Aguilar A broad-spectrum antiviral targeting entry of enveloped viruses Proc Natl Acad Sci U S A 107 2010 3157 3162
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 3157-3162
-
-
Wolf, M.C.1
Freiberg, A.N.2
Zhang, T.3
Akyol-Ataman, Z.4
Grock, A.5
Hong, P.W.6
Li, J.7
Watson, N.F.8
Fang, A.Q.9
Aguilar, H.C.10
-
30
-
-
84876804736
-
The global distribution and burden of dengue
-
S. Bhatt, P.W. Gething, O.J. Brady, J.P. Messina, A.W. Farlow, C.L. Moyes, J.M. Drake, J.S. Brownstein, A.G. Hoen, and O. Sankoh The global distribution and burden of dengue Nature 2013
-
(2013)
Nature
-
-
Bhatt, S.1
Gething, P.W.2
Brady, O.J.3
Messina, J.P.4
Farlow, A.W.5
Moyes, C.L.6
Drake, J.M.7
Brownstein, J.S.8
Hoen, A.G.9
Sankoh, O.10
-
31
-
-
84886937404
-
A novel inhibitor of dengue virus replication that targets the capsid protein
-
C.M. Byrd, D. Dai, D.W. Grosenbach, A. Berhanu, K.F. Jones, K.B. Cardwell, C. Schneider, K.A. Wineinger, J.M. Page, and C. Harver A novel inhibitor of dengue virus replication that targets the capsid protein Antimicrob Agents Chemother 2012
-
(2012)
Antimicrob Agents Chemother
-
-
Byrd, C.M.1
Dai, D.2
Grosenbach, D.W.3
Berhanu, A.4
Jones, K.F.5
Cardwell, K.B.6
Schneider, C.7
Wineinger, K.A.8
Page, J.M.9
Harver, C.10
-
32
-
-
84874639752
-
An iminosugar with potent inhibition of dengue virus infection in vivo
-
S.T. Perry, M.D. Buck, E.M. Plummer, R.A. Penmasta, H. Batra, E.J. Stavale, K.L. Warfield, R.A. Dwek, T.D. Butters, and D.S. Alonzi An iminosugar with potent inhibition of dengue virus infection in vivo Antiviral Res 98 2013 35 43
-
(2013)
Antiviral Res
, vol.98
, pp. 35-43
-
-
Perry, S.T.1
Buck, M.D.2
Plummer, E.M.3
Penmasta, R.A.4
Batra, H.5
Stavale, E.J.6
Warfield, K.L.7
Dwek, R.A.8
Butters, T.D.9
Alonzi, D.S.10
-
33
-
-
84869231440
-
Liposome-mediated delivery of iminosugars enhances efficacy against dengue virus in vivo
-
J.L. Miller, R. Lachica, A.C. Sayce, J.P. Williams, M. Bapat, R. Dwek, P.R. Beatty, E. Harris, and N. Zitzmann Liposome-mediated delivery of iminosugars enhances efficacy against dengue virus in vivo Antimicrob Agents Chemother 56 2012 6379 6386
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 6379-6386
-
-
Miller, J.L.1
Lachica, R.2
Sayce, A.C.3
Williams, J.P.4
Bapat, M.5
Dwek, R.6
Beatty, P.R.7
Harris, E.8
Zitzmann, N.9
-
34
-
-
84864925701
-
Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial
-
S. Watanabe, A.P. Rathore, C. Sung, F. Lu, Y.M. Khoo, J. Connolly, J. Low, E.E. Ooi, H.S. Lee, and S.G. Vasudevan Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial Antiviral Res 96 2012 32 35
-
(2012)
Antiviral Res
, vol.96
, pp. 32-35
-
-
Watanabe, S.1
Rathore, A.P.2
Sung, C.3
Lu, F.4
Khoo, Y.M.5
Connolly, J.6
Low, J.7
Ooi, E.E.8
Lee, H.S.9
Vasudevan, S.G.10
-
35
-
-
84355166551
-
Identification of an antioxidant small-molecule with broad-spectrum antiviral activity
-
R.G. Panchal, S.P. Reid, J.P. Tran, A.A. Bergeron, J. Wells, K.P. Kota, J. Aman, and S. Bavari Identification of an antioxidant small-molecule with broad-spectrum antiviral activity Antiviral Res 93 2012 23 29
-
(2012)
Antiviral Res
, vol.93
, pp. 23-29
-
-
Panchal, R.G.1
Reid, S.P.2
Tran, J.P.3
Bergeron, A.A.4
Wells, J.5
Kota, K.P.6
Aman, J.7
Bavari, S.8
-
36
-
-
77951240331
-
Antiviral activity of a small-molecule inhibitor of filovirus infection
-
T.K. Warren, K.L. Warfield, J. Wells, S. Enterlein, M. Smith, G. Ruthel, A.S. Yunus, M.S. Kinch, M. Goldblatt, and M.J. Aman Antiviral activity of a small-molecule inhibitor of filovirus infection Antimicrob Agents Chemother 54 2010 2152 2159
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2152-2159
-
-
Warren, T.K.1
Warfield, K.L.2
Wells, J.3
Enterlein, S.4
Smith, M.5
Ruthel, G.6
Yunus, A.S.7
Kinch, M.S.8
Goldblatt, M.9
Aman, M.J.10
-
37
-
-
77956436149
-
Advanced antisense therapies for postexposure protection against lethal filovirus infections
-
T.K. Warren, K.L. Warfield, J. Wells, D.L. Swenson, K.S. Donner, S.A. Van Tongeren, N.L. Garza, L. Dong, D.V. Mourich, and S. Crumley Advanced antisense therapies for postexposure protection against lethal filovirus infections Nat Med 16 2010 991 994
-
(2010)
Nat Med
, vol.16
, pp. 991-994
-
-
Warren, T.K.1
Warfield, K.L.2
Wells, J.3
Swenson, D.L.4
Donner, K.S.5
Van Tongeren, S.A.6
Garza, N.L.7
Dong, L.8
Mourich, D.V.9
Crumley, S.10
|