Osteoblastic cell secretome: A novel role for progranulin during risedronate treatment

Bone

Volumn 58, Issue , 2014, Pages 81-91

  Romanello, Milena ^a   Piatkowska, Elzbieta ^b   Antoniali, Giulia ^c   Cesaratto, Laura ^c   Vascotto, Carlo ^c   Iozzo, Renato V ^d   Delneri, Daniela ^b   Brancia, Francesco L ^e  

^a UNIVERSITY HOSPITAL OF UDINE   (Italy)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF UDINE   (Italy)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

^e AARHUS UNIVERSITY   (Denmark)

Author keywords

Bisphosphonates; Differential proteomics; Osteoblasts; Osteocytes; Progranulin; Risedronate

Indexed keywords

ADENOSYLHOMOCYSTEINASE; ATTRACTIN; CALPHOBINDIN II; CATHEPSIN B; CATHEPSIN L; CATHEPSIN X; CHAPERONIN 60; COMPLEMENT FACTOR H; ELONGATION FACTOR 2; FIBULIN 5; FILAMIN A; FOLLISTATIN RELATED PROTEIN; GALECTIN 3; GAMMA GLUTAMYL HYDROLASE; GELSOLIN; GLYCOGEN PHOSPHORYLASE; HEAT SHOCK COGNATE PROTEIN 70; HEAT SHOCK PROTEIN 90; HERMES ANTIGEN; LACTOFERRIN; LUMICAN; MICROSOMAL AMINOPEPTIDASE; MITOGEN ACTIVATED PROTEIN KINASE; POLYADENYLIC ACID BINDING PROTEIN; PROGRANULIN; RADIXIN; RISEDRONIC ACID; SCLEROPROTEIN; THROMBOSPONDIN 1;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; BIOLOGICAL ACTIVITY; CELL FUNCTION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME RELEASE; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; OSTEOBLAST; OSTEOCYTE; OSTEOLYSIS; OSTEOPOROSIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEOMICS; TANDEM MASS SPECTROMETRY;

2-DE; 3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE; BISPHOSPHONATES; DIFFERENTIAL PROTEOMICS; ECL; ENHANCED CHEMILUMINESCENCE; FARNESYL PYROPHOSPHATE SYNTHASE; FBS; FETAL BOVINE SERUM; FPPS; IPP; ISOPENTYL DIPHOSPHATE; LC; LIQUID CHROMATOGRAPHY; MALDI-TOF; MATRIX-ASSISTED LASER DESORPTION/IONIZATION-TIME OF FLIGHT; MLO-Y4; MS/MS; MTT; MURINE LONG BONE OSTEOCYTE-Y4; OSTEOBLASTS; OSTEOCYTES; PAGE; PHENYLMETHYLSULFONYL FLUORIDE; PMSF; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYVINYLIDENE FLUORIDE; PROGRANULIN; PVDF; RISEDRONATE; SDS; SODIUM DODECYL SULFATE; TANDEM MASS SPECTROMETRY; TFA; TRIFLUOROACETIC ACID; TWO-DIMENSIONAL GEL ELECTROPHORESIS;

ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ETIDRONIC ACID; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MASS SPECTROMETRY; MICE; OSTEOBLASTS; PROTEOME; REPRODUCIBILITY OF RESULTS; TIME FACTORS;

EID: 84886799525     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2013.10.003     Document Type: Article

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