Genetic alterations associated with progression from pancreatic intraepithelial neoplasia to invasive pancreatic tumor

Gastroenterology

Volumn 145, Issue 5, 2013, Pages

  Murphy, Stephen J ^a   Hart, Steven N ^a   Lima, Joema Felipe ^a   Kipp, Benjamin R ^a   Klebig, Mitchell ^a   Winters, Jennifer L ^a   Szabo, Csilla ^b   Zhang, Lizhi ^a   Eckloff, Bruce W ^a   Petersen, Gloria M ^a   Scherer, Steven E ^c   Gibbs, Richard A ^c   McWilliams, Robert R ^a   Vasmatzis, George ^a   Couch, Fergus J ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF DELAWARE   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

LCM; Pancreas; Tumorigenesis; Whole Genome Amplification

Indexed keywords

GAP JUNCTION PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE;

ACTIN FILAMENT; ARTICLE; CANCER PATIENT; CARCINOGENESIS; CELL CYCLE REGULATION; CONTROLLED STUDY; DNA DAMAGE; DNA SEQUENCE; EXOME; HUMAN; HUMAN TISSUE; LASER CAPTURE MICRODISSECTION; MUTAGENESIS; NERVE FIBER; ONCOGENE; ONCOGENE K RAS; PANCREAS ADENOCARCINOMA; PANCREAS ADENOMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOMATIC MUTATION; TP53 GENE; TUMOR GROWTH; TUMOR INVASION;

EID: 84886789716     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2013.07.049     Document Type: Article

References (37)

1. T.L. Fitzgerald, Z.J. Hickner, and M. Schmitz Changing incidence of pancreatic neoplasms: a 16-year review of statewide tumor registry Pancreas 37 2008 134 138
2. A.L. Cubilla, and P.J. Fitzgerald Pancreas cancer (non-endocrine) Clin Bull 8 2008 91 99
3. A. Jemal, R. Siegel, and E. Ward Cancer statistics, 2009 CA Cancer J Clin 59 2009 225 249
4. H.G. Smeenk, T.C. Tran, and J. Erdmann Survival after surgical management of pancreatic adenocarcinoma: does curative and radical surgery truly exist? Langenbecks Arch Surg 390 2005 94 103
5. T.A. Sohn, C.J. Yeo, and J.L. Cameron Resected adenocarcinoma of the pancreas-616 patients: results, outcomes, and prognostic indicators J Gastrointest Surg 4 2000 567 579
6. G. Kloppel, R.H. Hruban, and D.S. Longnecker Ductal adenocarcinoma of the pancreas, WHO classification of tumors: pathology and genetics of the digestive system 2000 IARC Press Lyon
7. R.H. Hruban, K. Takaori, and D.S. Klimstra An illustrated consensus on the classification of PanIN and intraductal papillary mucinous neoplasms Am J Surg Pathol 28 2004 977 987
8. S.R. Hingorani, E.F. Petricoin, and A. Maitra Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse Cancer Cell 4 2003 437 450
9. J. Kim, H.A. Reber, and S.M. Dry Unfavourable prognosis associated with K-ras gene mutation in pancreatic cancer surgical margins Gut 55 2006 1598 1605
10. S.J. Murphy, J.C. Cheville, and S. Zarei Mate-pair sequencing of WGA DNA following LCM of prostate cancer DNA Res 19 2012 395 406
11. A. McKenna, M. Hanna, and E. Banks The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data Genome Res 20 2010 1297 1303
12. Y.W. Asmann, S. Middha, and A. Hossain TREAT: a bioinformatics tool for variant annotations and visualizations in targeted and exome sequencing data Bioinformatics 28 2012 277 278
13. A. McKenna, M. Hanna, and E. Banks The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data Genome Res 20 2010 1297 1303
14. D.E. Larson, C.C. Harris, and K. Chen SomaticSniper: identification of somatic point mutations in whole genome sequencing data Bioinformatics 28 2012 311 317
15. P.C. Ng, and S. Henikoff Predicting the effects of amino-acid substitutions on protein function Annu Rev Genomics Hum Genet 7 2006 61 80
16. S. Bauer, and G.J. Going Bayesian: model-based gene set analysis of genome-scale data Nucleic Acids Res 38 2010 3523 3535
17. S. Jones, X. Zhang, and D.W. Parsons Core signaling pathways in human pancreatic cancers revealed by global genomic analyses Science 321 2008 1801 1806
18. M. Janakiraman, E. Vakiani, and Z. Zeng Genomic and biological characterization of exon 4 KRAS mutations in human cancer Cancer Res 70 2010 5901 5911
19. S. Mukherjee, R. Poddar, and I. Deb Dephosphorylation of specific sites in the kinase-specificity sequence domain leads to ubiquitin-mediated degradation of the tyrosine phosphatase STEP Biochem J 440 2011 115 125
20. N.J. Roberts, Y. Jiao, and J. Yu ATM mutations in patients with hereditary pancreatic cancer cancer Discovery 2 2012 41 46
21. T. Sugiura, A. Yamaguchi, and K. Miyamoto A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95 Exp Cell Res 314 2008 1519 1528
22. N.A. Perry, M. Shriver, and M.G. Mameza Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance FASEB J 26 2012 2764 2775
23. S. Waalkes, F. Atschekzei, and M.W. Kramer Fibronectin 1 mRNA expression correlates with advanced disease in renal cancer BMC Cancer 10 2010 503 508
24. C.C. Morton, M.C. Nussenzweig, and R. Sousa Mapping and characterization of an X-linked processed gene related to MYCL1 Genomics 4 1989 367 375
25. Y.E. Nikiforov, and M.N. Nikiforova Molecular genetics and diagnosis of thyroid cancer Nat Rev Endocrinol 7 2011 569 580
26. K.H. Chang, Y. Chen, and T.T. Chen A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein Proc Natl Acad Sci U S A 94 1997 9040 9045
27. K.I. Ansari, and S.S. Mandal Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing FEBS J 277 2010 1790 1804
28. S. Frietz, R. Wang, and L. Yao Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3 Genome Biol 13 2012 R52
29. J. Wu, H. Matthaei, and A. Maitra Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development Sci Transl Med 3 2011 92ra66
30. L. Antoni, N. Sodha, and I. Collins CHK2 kinase: cancer susceptibility and cancer therapy- two sides of the same coin? Nat Rev Cancer 7 2007 925 936
31. A.V. Biankin, N. Waddell, and K.S. Kassahn Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes Nature 491 2012 399 405
32. M. Kamal, A.M. Shaaban, and L. Zhang Loss of CSMD1 expression is associated with high tumour grade and poor survival in invasive ductal breast carcinoma Breast Cancer Res Treat 121 2010 555 563
33. B.L. Adamsen, K.L. Kravik, and O.P. Clausen Apoptosis, cell cycle progression and gene expression in TP53-depleted HCT116 colon cancer cells in response to short-term 5-fluorouracil treatment Int J Oncol 31 2007 1491 1500
34. F.E. Bleeker, S. Lamba, and M. Rodolfo Mutational profiling of cancer candidate genes in glioblastoma, melanoma and pancreatic carcinoma reveals a snapshot of their genomic landscapes Hum Mutat 30 2009 E451 E459
35. P. Wei, H. Tang, and D. Li Insights into pancreatic cancer etiology from pathway analysis of genome-wide association study data PLoS One 7 2012 e46887
36. D.M. Simeone, T. Pham, and C.D. Logsdon Disruption of TGFbeta signaling pathways in human pancreatic cancer cells Ann Surg 232 2000 73 80
37. J. Kim, H.A. Reber, and S.M. Dry Unfavourable prognosis associated with K-ras gene mutation in pancreatic cancer surgical margins Gut 55 2006 1598 1605