Mutation of the conserved calcium-binding motif in Neisseria gonorrhoeae PilC1 impacts adhesion but not piliation

Infection and Immunity

Volumn 81, Issue 11, 2013, Pages 4279-4289

  Cheng, Yuan ^a,c   Johnson, Michael D L ^a,d   Burillo Kirch, Christine ^a   Mocny, Jeffrey C ^a   Anderson, James E ^a   Garrett, Christopher K ^a   Redinbo, Matthew R ^a,b   Thomas, Christopher E ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b The University of North Carolina at Chapel Hill   (United States)

^c UNIVERSITY OF KANSAS   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; CALCIUM BINDING PROTEIN; MONOCLONAL ANTIBODY; PILC1 PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; CALCIUM; FIMBRIA PROTEIN; MUTANT PROTEIN; PILC PROTEIN, NEISSERIA GONORRHOEAE;

ARTICLE; BACTERIAL STRAIN; BACTERIUM ADHERENCE; BACTERIUM PILUS; CALCIUM BINDING; CELL CULTURE; COLONY FORMING UNIT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GONORRHEA; HUMAN; HUMAN CELL; NEISSERIA GONORRHOEAE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; PSEUDOMONAS AERUGINOSA; SCANNING ELECTRON MICROSCOPY; SEXUALLY TRANSMITTED DISEASE; UTERINE CERVIX EPITHELIUM; BINDING SITE; CELL LINE; EPITHELIUM CELL; FIMBRIA; GENETICS; METABOLISM; MICROBIOLOGY; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

ADHESINS, BACTERIAL; BACTERIAL ADHESION; BINDING SITES; CALCIUM; CELL LINE; DNA MUTATIONAL ANALYSIS; EPITHELIAL CELLS; FIMBRIAE PROTEINS; FIMBRIAE, BACTERIAL; HUMANS; MUTANT PROTEINS; NEISSERIA GONORRHOEAE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY;

EID: 84886776754     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00493-13     Document Type: Article

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