Intracellular trafficking and cellular uptake mechanism of mPEG-PLGA-PLL and mPEG-PLGA-PLL-Gal nanoparticles for targeted delivery to hepatomas

Biomaterials

Volumn 35, Issue 2, 2014, Pages 760-770

  Liu, Peifeng ^a   Sun, Yanming ^a   Wang, Qi ^a   Sun, Ying ^a   Li, He ^a   Duan, Yourong ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cell uptake; Hepatoma; Intracellular trafficking; Nanoparticles; Organelle morphology

Indexed keywords

CELL UPTAKE; HEPATOMA; INTRACELLULAR DELIVERY; INTRACELLULAR DISTRIBUTION; INTRACELLULAR TRAFFICKING; RECEPTOR-MEDIATED ENDOCYTOSIS; TARGETED DELIVERY; THERAPEUTIC EFFICIENCY;

AMINO ACIDS; CARBOXYLIC ACIDS; COPOLYMERS; CYTOLOGY; EFFICIENCY; MOLECULAR BIOLOGY; MORPHOLOGY; MOTION PICTURE EXPERTS GROUP STANDARDS; NANOPARTICLES; TUMORS;

CELLS;

AMILORIDE; CHLORPROMAZINE; CLATHRIN; GENISTEIN; MONOMETHOXY (POLYETHYLENE GLYCOL) 4 O BETA D GALACTOPYRANOSYL D GLUCONIC ACID; MONOMETHOXY (POLYETHYLENE GLYCOL) POLY (D L LACTIDE CO GLYCOLIDE) POLY (L LSINE); NANOPARTICLE; NYSTATIN; POLYMER; SIALIC ACID; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIGEN ANTIBODY REACTION; ARTICLE; CANCER THERAPY; CELL MIGRATION; CELL ORGANELLE; CELL PROLIFERATION; CELL VIABILITY; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; DISPERSION; DRUG DELIVERY SYSTEM; ENCAPSULATION; ENDOCYTOSIS; ENDOSOME; ENERGY CONSUMPTION; ENERGY YIELD; ENZYME ACTIVITY; FEMALE; GLYCOLYSIS; GOLGI COMPLEX; HEPATOMA CELL; INTERNALIZATION; INTRACELLULAR TRANSPORT; LIVER CELL CARCINOMA; LYSOSOME; MOUSE; NONHUMAN; OXIDATION; PHYSICAL CHEMISTRY; PINOCYTOSIS; PRIORITY JOURNAL; ZETA POTENTIAL;

MUS;

CELL UPTAKE; HEPATOMA; INTRACELLULAR TRAFFICKING; NANOPARTICLES; ORGANELLE MORPHOLOGY;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; CLATHRIN; DRUG CARRIERS; ENDOCYTOSIS; FEMALE; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MICE; MICE, INBRED BALB C; N-ACETYLNEURAMINIC ACID; NANOPARTICLES; POLYESTERS; POLYETHYLENE GLYCOLS; POLYLYSINE; RHODAMINES;

EID: 84886746611     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.10.020     Document Type: Article

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