BDgene: A genetic database for bipolar disorder and its overlap with schizophrenia and major depressive disorder

Biological Psychiatry

Volumn 74, Issue 10, 2013, Pages 727-733

  Chang, Su Hua ^a   Gao, Lei ^a,b   Li, Zhao ^a,b   Zhang, Wei Na ^a,b   Du, Yang ^a,b   Wang, Jing ^a  

^a INSTITUTE OF PSYCHOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

BDgene; bipolar disorder; data analysis; genetic database; genetic overlap; major depressive disorder; schizophrenia

Indexed keywords

ANK3 GENE; ARTICLE; BDNF GENE; BIPOLAR DISORDER; CACNA1C GENE; COMT GENE; COPY NUMBER VARIATION; DAOA GENE; DISC1 GENE; DRD2 GENE; GENE; GENE INTERACTION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC VARIABILITY; HAPLOTYPE; HEREDITY; HUMAN; MAJOR DEPRESSION; MTHFR GENE; NRG1 GENE; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; SLC6A4 GENE;

BDGENE; BIPOLAR DISORDER; DATA ANALYSIS; GENETIC DATABASE; GENETIC OVERLAP; MAJOR DEPRESSIVE DISORDER; SCHIZOPHRENIA;

BIPOLAR DISORDER; DATABASES, GENETIC; DEPRESSIVE DISORDER, MAJOR; HUMANS; SCHIZOPHRENIA;

EID: 84886716545     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.04.016     Document Type: Article

References (64)

1. F.K. Goodwin, K.R. Jamison, and S.N. Ghaemi Manic-Depressive Illness: Bipolar Disorders and Recurrent Depression 2nd ed 2007 Oxford University Press New York and Oxford
2. K.R. Merikangas, H.S. Akiskal, J. Angst, P.E. Greenberg, R.M. Hirschfeld, and M. Petukhova Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication Arch Gen Psychiatry 64 2007 543 552
3. R.C. Kessler, K.A. McGonagle, S. Zhao, C.B. Nelson, M. Hughes, and S. Eshleman Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey Arch Gen Psychiatry 51 1994 8 19
4. D.M. Novick, H.A. Swartz, and E. Frank Suicide attempts in bipolar I and bipolar II disorder: A review and meta-analysis of the evidence Bipolar Disord 12 2010 1 9
5. R.M. Hirschfeld, and L.A. Vornik Bipolar disorder - costs and comorbidity Am J Manag Care 11 2005 S85 S90
6. J.H. Barnett, and J.W. Smoller The genetics of bipolar disorder Neuroscience 164 2009 331 343
7. J. Huang, R.H. Perlis, P.H. Lee, A.J. Rush, M. Fava, and G.S. Sachs Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression Am J Psychiatry 167 2010 1254 1263
8. M.A. Taylor, S.A. Berenbaum, V.C. Jampala, and C.R. Cloninger Are schizophrenia and affective disorder related? Preliminary data from a family study Am J Psychiatry 150 1993 278 285
9. V. Valles, J. Van Os, R. Guillamat, B. Gutierrez, M. Campillo, and P. Gento Increased morbid risk for schizophrenia in families of in-patients with bipolar illness Schizophr Res 42 2000 83 90
10. J.W. Smoller, and C.T. Finn Family, twin, and adoption studies of bipolar disorder Am J Med Genet C Semin Med Genet 123C 2003 48 58
11. A. Serretti, and L. Mandelli The genetics of bipolar disorder: Genome "hot regions," genes, new potential candidates and future directions Mol Psychiatry 13 2008 742 771
12. J. Offord Genetic approaches to a better understanding of bipolar disorder Pharmacol Ther 133 2012 133 141
13. Q. Cordeiro, M.E. Talkowski, K.V. Chowdari, J. Wood, V. Nimgaonkar, and H. Vallada Association and linkage analysis of RGS4 polymorphisms with schizophrenia and bipolar disorder in Brazil Genes Brain Behav 4 2005 45 50
14. K.V. Chowdari, K. Mirnics, P. Semwal, J. Wood, E. Lawrence, and T. Bhatia Association and linkage analyses of RGS4 polymorphisms in schizophrenia Hum Mol Genet 11 2002 1373 1380
15. Y. Li, Q. Zhao, Z. Zhang, P. Wang, R. Che, and W. Tang Association study between RGS4 and bipolar disorder in the Chinese Han population Psychiatr Genet 20 2010 130 132
16. M.D. Fallin, V.K. Lasseter, D. Avramopoulos, K.K. Nicodemus, P.S. Wolyniec, and J.A. McGrath Bipolar I disorder and schizophrenia: A 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios Am J Hum Genet 77 2005 918 936
17. D.P. Prata, G. Breen, J. Munro, M. Sinclair, S. Osborne, and T. Li Bipolar 1 disorder is not associated with the RGS4, PRODH, COMT and GRK3 genes Psychiatr Genet 16 2006 229 230
18. T. Kato Molecular genetics of bipolar disorder and depression Psychiatry Clin Neurosci 61 2007 3 19
19. L.-C. Tranchevent, F.B. Capdevila, D. Nitsch, B. De Moor, P. De Causmaecker, and Y. Moreau A guide to web tools to prioritize candidate genes Brief Bioinform 12 2010 22 32
20. C. O'Dushlaine, E. Kenny, E. Heron, G. Donohoe, M. Gill, and D. Morris Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility Mol Psychiatry 16 2011 286 292
21. T.A. Manolio, L.D. Brooks, and F.S. Collins A HapMap harvest of insights into the genetics of common disease J Clin Invest 118 2008 1590 1605
22. K. Wang, M. Li, and H. Hakonarson Analysing biological pathways in genome-wide association studies Nat Rev Genet 11 2010 843 854
23. A. Torkamani, E.J. Topol, and N.J. Schork Pathway analysis of seven common diseases assessed by genome-wide association Genomics 92 2008 265 272
24. K. Askland, C. Read, and J. Moore Pathways-based analyses of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission Hum Genet 125 2009 63 79
25. L. Chen, L. Zhang, Y. Zhao, L. Xu, Y. Shang, and Q. Wang Prioritizing risk pathways: A novel association approach to searching for disease pathways fusing SNPs and pathways Bioinformatics 25 2009 237 242
26. P. Holmans, E.K. Green, J.S. Pahwa, M.A. Ferreira, S.M. Purcell, and P. Sklar Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder Am J Hum Genet 85 2009 13 24
27. G. Peng, L. Luo, H. Siu, Y. Zhu, P. Hu, and S. Hong Gene and pathway-based second-wave analysis of genome-wide association studies Eur J Hum Genet 18 2010 111 117
28. K. Zhang, S. Cui, S. Chang, L. Zhang, and J. Wang i-GSEA4GWAS: A web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study Nucleic Acids Res 38 2010 W90 W95
29. L. Zhang, S. Chang, Z. Li, K. Zhang, Y. Du, and J. Ott ADHDgene: A genetic database for attention deficit hyperactivity disorder Nucleic Acids Res 40 2012 D1003 D1009
30. E. Lander, and L. Kruglyak Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results Nat Genet 11 1995 241 247
31. L.-C. Tranchevent, R. Barriot, S. Yu, S. Van Vooren, P. Van Loo, and B. Coessens Endeavour update: A web resource for gene prioritization in multiple species Nucleic Acids Res 36 2008 W377 W384
32. S. Aerts, D. Lambrechts, S. Maity, P. Van Loo, B. Coessens, and F. De Smet Gene prioritization through genomic data fusion Nat Biotech 24 2006 537 544
33. Y. Chen, W. Wang, Y. Zhou, R. Shields, S.K. Chanda, and R.C. Elston In silico gene prioritization by integrating multiple data sources PLoS One 6 2011 e21137
34. J. Chen, E.E. Bardes, B.J. Aronow, and A.G. Jegga ToppGene Suite for gene list enrichment analysis and candidate gene prioritization Nucleic Acids Res 37 2009 W305 W311
35. Y.A. Chen, L.P. Tripathi, and K. Mizuguchi TargetMine, an integrated data warehouse for candidate gene prioritisation and target discovery PLoS One 6 2011 e17844
36. S. Chang, W. Zhang, L. Gao, and J. Wang Prioritization of candidate genes for attention deficit hyperactivity disorder by computational analysis of multiple data sources Protein Cell 3 2012 526 534
37. M.A. Ferreira, M.C. O'Donovan, Y.A. Meng, I.R. Jones, D.M. Ruderfer, and L. Jones Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder Nat Genet 40 2008 1056 1058
38. Y. Liu, D.H. Blackwood, S. Caesar, E.J. de Geus, A. Farmer, and M.A. Ferreira Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder Mol Psychiatry 16 2011 2 4
39. Green EK, Hamshere M, Forty L, Gordon-Smith K, Fraser C, Russell E, et al. (2012): Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample. Mol Psychiatry.
40. A.E. Baum, N. Akula, M. Cabanero, I. Cardona, W. Corona, and B. Klemens A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder Mol Psychiatry 13 2008 197 207
41. E. Hattori, T. Toyota, Y. Ishitsuka, Y. Iwayama, K. Yamada, and H. Ujike Preliminary genome-wide association study of bipolar disorder in the Japanese population Am J Med Genet B Neuropsychiatr Genet 150B 2009 1110 1117
42. E.N. Smith, C.S. Bloss, J.A. Badner, T. Barrett, P.L. Belmonte, and W. Berrettini Genome-wide association study of bipolar disorder in European American and African American individuals Mol Psychiatry 14 2009 755 763
43. Wellcome Trust Case Control Consortium Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls Nature 447 2007 661 678
44. S. Purcell, B. Neale, K. Todd-Brown, L. Thomas, M.A. Ferreira, and D. Bender PLINK: A tool set for whole-genome association and population-based linkage analyses Am J Hum Genet 81 2007 559 575
45. A. Liberzon, A. Subramanian, R. Pinchback, H. Thorvaldsdottir, P. Tamayo, and J.P. Mesirov Molecular signatures database (MSigDB) 3.0 Bioinformatics 27 2011 1739 1740
46. M. Kanehisa, S. Goto, M. Furumichi, M. Tanabe, and M. Hirakawa KEGG for representation and analysis of molecular networks involving diseases and drugs Nucleic Acids Res 38 2010 D355 D360
47. P. Flicek, M.R. Amode, D. Barrell, K. Beal, S. Brent, and Y. Chen Ensembl 2011 Nucleic Acids Res 39 2011 D800 D806
48. N.C. Allen, S. Bagade, M.B. McQueen, J.P. Ioannidis, F.K. Kavvoura, and M.J. Khoury Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: The SzGene database Nat Genet 40 2008 827 834
49. L. Guo, W. Zhang, S. Chang, L. Zhang, J. Ott, and J. Wang MK4MDD: A Multi-level knowledge base and analysis platform for major depressive disorder PLoS One 7 2012 e46335
50. D.M. Altshuler, R.A. Gibbs, L. Peltonen, E. Dermitzakis, S.F. Schaffner, and F. Yu Integrating common and rare genetic variation in diverse human populations Nature 467 2010 52 58
51. J. Erdmann, A. Grosshennig, P.S. Braund, I.R. Konig, C. Hengstenberg, and A.S. Hall New susceptibility locus for coronary artery disease on chromosome 3q22.3 Nat Genet 41 2009 280 282
52. M. Ashburner, C.A. Ball, J.A. Blake, D. Botstein, H. Butler, and J.M. Cherry Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium Nature Genet 25 2000 25 29
53. T.S. Keshava Prasad, R. Goel, K. Kandasamy, S. Keerthikumar, S. Kumar, and S. Mathivanan Human Protein Reference Database - 2009 update Nucleic Acids Res 37 2009 D767 D772
54. W. Huang da, B.T. Sherman, and R.A. Lempicki Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nature Protoc 4 2009 44 57
55. W. Huang da, B.T. Sherman, and R.A. Lempicki Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists Nucleic Acids Res 37 2009 1 13
56. L.D. Stein, C. Mungall, S. Shu, M. Caudy, M. Mangone, and A. Day The generic genome browser: A building block for a model organism system database Genome Res 12 2002 1599 1610
57. J.L. Stein, X. Hua, S. Lee, A.J. Ho, A.D. Leow, and A.W. Toga Voxelwise genome-wide association study (vGWAS) Neuroimage 53 2010 1160 1174
58. W.D. Taylor, S. Benjamin, D.R. McQuoid, M.E. Payne, R.R. Krishnan, and J.R. MacFall AGTR1 gene variation: association with depression and frontotemporal morphology Psychiatry Res 202 2012 104 109
59. M. Gratacos, J. Costas, R. de Cid, M. Bayes, J.R. Gonzalez, and E. Baca-Garcia Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment Am J Med Genet B Neuropsychiatr Genet 150B 2009 808 816
60. I. Pedroso, A. Lourdusamy, M. Rietschel, M.M. Nothen, S. Cichon, and P. McGuffin Common genetic variants and gene-expression changes associated with bipolar disorder are over-represented in brain signaling pathway genes Biol Psychiatry 72 2012 311 317
61. R.C. Padmos, L. Bekris, E.M. Knijff, H. Tiemeier, R.W. Kupka, and D. Cohen A high prevalence of organ-specific autoimmunity in patients with bipolar disorder Biol Psychiatry 56 2004 476 482
62. R.C. Drexhage, L. van der Heul-Nieuwenhuijsen, R.C. Padmos, N. van Beveren, D. Cohen, and M.A. Versnel Inflammatory gene expression in monocytes of patients with schizophrenia: Overlap and difference with bipolar disorder. A study in naturalistically treated patients Int J Neuropsychopharmacol 13 2010 1369 1381
63. K. Munkholm, M. Vinberg, and L. Vedel Kessing Cytokines in bipolar disorder: A systematic review and meta-analysis J Affect Disord 144 2013 16 27
64. M.J. Kempton, G. Ruberto, E. Vassos, R. Tatarelli, P. Girardi, and D. Collier Effects of the CACNA1C risk allele for bipolar disorder on cerebral gray matter volume in healthy individuals Am J Psychiatry 166 2009 1413 1414