Phosphorylation and mRNA splicing of collapsin response mediator protein-2 determine inhibition of rho-associated protein kinase (ROCK) II function in carcinoma cell migration and invasion

Journal of Biological Chemistry

Volumn 288, Issue 43, 2013, Pages 31229-31240

  Morgan Fisher, Marie ^a   Couchman, John R ^a   Yoneda, Atsuko ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC DOMAINS; CELLULAR PROCESS; COLON CARCINOMA CELLS; GLYCOGEN SYNTHASE KINASE; HUMAN BREAST CARCINOMA CELLS; INHIBITORY FUNCTION; INTERACTION SITE; SPLICE VARIANTS;

ENZYMES; PHOSPHORYLATION; PROTEINS;

ROCKS;

COLLAPSIN RESPONSE MEDIATOR PROTEIN 2; GLYCOGEN SYNTHASE KINASE 3; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; RHO ASSOCIATED PROTEIN KINASE II; RHO KINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL INVASION; CELL MIGRATION; COLON CARCINOMA; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME REGULATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; RNA SPLICING; SPLICING DEFECT;

CARCINOMA; CELL INVASION; CELL MIGRATION; COLLAPSIN RESPONSE MEDIATOR PROTEIN-2; CRMP-2 PHOSPHORYLATION; GLYCOGEN SYNTHASE KINASE 3; PROTEIN-SERINE/THREONINE KINASE; RHO GTPASES; RHO-ASSOCIATED PROTEIN KINASE II;

ANIMALS; BREAST NEOPLASMS; CARCINOMA; CELL LINE, TUMOR; CELL MOVEMENT; COLONIC NEOPLASMS; FEMALE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RHO-ASSOCIATED KINASES; RNA SPLICING; RNA, MESSENGER; RNA, NEOPLASM;

EID: 84886711106     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.505602     Document Type: Article

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