메뉴 건너뛰기




Volumn 29, Issue 11, 2013, Pages 1428-1433

HIV and interferon regulatory factor 1: A story of manipulation and control

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; INTERFERON REGULATORY FACTOR 1;

EID: 84886648229     PISSN: 08892229     EISSN: 19318405     Source Type: Journal    
DOI: 10.1089/aid.2013.0098     Document Type: Review
Times cited : (11)

References (52)
  • 1
    • 84859919465 scopus 로고    scopus 로고
    • Lessons learned from HIV-1 vaccine trials: New priorities and directions
    • McMichael AJ and Haynes BF: Lessons learned from HIV-1 vaccine trials: New priorities and directions. Nat Immunol 2012; 13: 423-427.
    • (2012) Nat Immunol , vol.13 , pp. 423-427
    • McMichael, A.J.1    Haynes, B.F.2
  • 2
    • 44049108744 scopus 로고    scopus 로고
    • Toward an AIDS vaccine
    • Walker BD and Burton DR: Toward an AIDS vaccine. Science 2008; 320: 760-764.
    • (2008) Science , vol.320 , pp. 760-764
    • Walker, B.D.1    Burton, D.R.2
  • 3
    • 77958182786 scopus 로고    scopus 로고
    • Immune evasion and counteraction of restriction factors by HIV-1 and other primate lentiviruses
    • Kirchhoff F: Immune evasion and counteraction of restriction factors by HIV-1 and other primate lentiviruses. Cell Host Microbe 2010; 8: 55-67.
    • (2010) Cell Host Microbe , vol.8 , pp. 55-67
    • Kirchhoff, F.1
  • 5
    • 73349101856 scopus 로고    scopus 로고
    • Dynamic evolution of immune system regulators: The history of the interferon regulatory factor family
    • Nehyba J, Hrdlicková R, and Bose HR: Dynamic evolution of immune system regulators: The history of the interferon regulatory factor family. Mol Biol Evol 2009; 26: 2539-2550.
    • (2009) Mol Biol Evol , vol.26 , pp. 2539-2550
    • Nehyba, J.1    Hrdlicková, R.2    Bose, H.R.3
  • 7
    • 77951794488 scopus 로고    scopus 로고
    • Global characterization of interferon regulatory factor (IRF) genes in vertebrates: Glimpse of the diversification in evolution
    • Huang B, Qi ZT, Xu Z, and Nie P: Global characterization of interferon regulatory factor (IRF) genes in vertebrates: Glimpse of the diversification in evolution. BMC Immunol 2010; 11: 22.
    • (2010) BMC Immunol , vol.11 , pp. 22
    • Huang, B.1    Qi, Z.T.2    Xu, Z.3    Nie, P.4
  • 8
    • 1342326795 scopus 로고    scopus 로고
    • On the role of interferon regulatory factors in HIV-1 replication
    • Marsili G, Borsetti A, and Sgarbanti M: On the role of interferon regulatory factors in HIV-1 replication. Ann NY Acad Sci 2003; 1010: 29-42.
    • (2003) Ann NY Acad Sci , vol.1010 , pp. 29-42
    • Marsili, G.1    Borsetti, A.2    Sgarbanti, M.3
  • 10
    • 0024114474 scopus 로고
    • Evidence for a nuclear factor(s), IRF-1, mediating induction and silencing properties to human IFN-beta gene regulatory elements
    • Fujita J, Sakakibara J, Sudo Y, et al.: Evidence for a nuclear factor(s), IRF-1, mediating induction and silencing properties to human IFN-beta gene regulatory elements. EMBO J 1988; 7: 3397.
    • (1988) EMBO J , vol.7 , pp. 3397
    • Fujita, J.1    Sakakibara, J.2    Sudo, Y.3
  • 11
    • 0030760672 scopus 로고    scopus 로고
    • Sequence elements downstream of the human immunodeficiency virus type 1 long terminal repeat are required for efficient viral gene transcription
    • Liang C, Li X, Quan Y, Laughrea M, Kleiman L, Hiscott J, et al.: Sequence elements downstream of the human immunodeficiency virus type 1 long terminal repeat are required for efficient viral gene transcription. J Mol Biol 1997; 272: 167-177.
    • (1997) J Mol Biol , vol.272 , pp. 167-177
    • Liang, C.1    Li, X.2    Quan, Y.3    Laughrea, M.4    Kleiman, L.5    Hiscott, J.6
  • 12
    • 0028987950 scopus 로고
    • Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD4 T lymphocytes
    • Alcamí J, Lain de Lera T, Folgueira L, et al.: Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD4 T lymphocytes. EMBO J 1995; 14: 1552.
    • (1995) EMBO J , vol.14 , pp. 1552
    • Alcam, J.1    Lain De Lera, T.2    Folgueira, L.3
  • 13
    • 0024380583 scopus 로고
    • Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes
    • Harada H, Fujita T, Miyamoto M, Kimura Y, Maruyama M, Furia A, et al.: Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell 1989; 58: 729-739.
    • (1989) Cell , vol.58 , pp. 729-739
    • Harada, H.1    Fujita, T.2    Miyamoto, M.3    Kimura, Y.4    Maruyama, M.5    Furia, A.6
  • 14
    • 0030070301 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 and vaccinia virus infection by a dominant negative factor of the interferon regulatory factor family expressed in monocytic cells
    • Thornton AM, Buller RM, DeVico AL, Wang IM, and Ozato K: Inhibition of human immunodeficiency virus type 1 and vaccinia virus infection by a dominant negative factor of the interferon regulatory factor family expressed in monocytic cells. Proc Natl Acad Sci USA 1996; 93: 383-387.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 383-387
    • Thornton, A.M.1    Buller, R.M.2    Devico, A.L.3    Wang, I.M.4    Ozato, K.5
  • 15
    • 79957998255 scopus 로고    scopus 로고
    • HIV infection of dendritic cells subverts the interferon induction pathway via IRF1 and inhibits type 1 interferon production
    • Harman AN, Lai J, Turville S, Samarajiwa S, Gray L, Marsden V, et al.: HIV infection of dendritic cells subverts the interferon induction pathway via IRF1 and inhibits type 1 interferon production. Blood 2011; 118: 298-308.
    • (2011) Blood , vol.118 , pp. 298-308
    • Harman, A.N.1    Lai, J.2    Turville, S.3    Samarajiwa, S.4    Gray, L.5    Marsden, V.6
  • 16
    • 0037141146 scopus 로고    scopus 로고
    • Modulation of human immunodeficiency virus 1 replication by interferon regulatory factors
    • Sgarbanti M, Borsetti A, Moscufo N, Bellocchi MC, Ridolfi B, Nappi F, et al.: Modulation of human immunodeficiency virus 1 replication by interferon regulatory factors. J Exp Med 2002; 195: 1359-1370.
    • (2002) J Exp Med , vol.195 , pp. 1359-1370
    • Sgarbanti, M.1    Borsetti, A.2    Moscufo, N.3    Bellocchi, M.C.4    Ridolfi, B.5    Nappi, F.6
  • 17
    • 15044364699 scopus 로고    scopus 로고
    • Analysis of the signal transduction pathway leading to human immunodeficiency virus-1-induced interferon regulatory factor-1 upregulation
    • Sgarbanti M, Marsili G, Remoli AL, Ridolfi B, Stellacci E, Borsetti A, et al.: Analysis of the signal transduction pathway leading to human immunodeficiency virus-1-induced interferon regulatory factor-1 upregulation. Ann NY Acad Sci 2004; 1030: 187-195.
    • (2004) Ann NY Acad Sci , vol.1030 , pp. 187-195
    • Sgarbanti, M.1    Marsili, G.2    Remoli, A.L.3    Ridolfi, B.4    Stellacci, E.5    Borsetti, A.6
  • 18
    • 84864491073 scopus 로고    scopus 로고
    • HIV-1 infection of human macrophages directly induces viperin which inhibits viral production
    • Nasr N, Maddocks S, Turville SG, Harman AN, Woolger N, Helbig KJ, et al.: HIV-1 infection of human macrophages directly induces viperin which inhibits viral production. Blood 2012; 120: 778-788.
    • (2012) Blood , vol.120 , pp. 778-788
    • Nasr, N.1    Maddocks, S.2    Turville, S.G.3    Harman, A.N.4    Woolger, N.5    Helbig, K.J.6
  • 19
    • 41149122048 scopus 로고    scopus 로고
    • IRF-1 is required for full NF-kappaB transcriptional activity at the human immunodeficiency virus type 1 long terminal repeat enhancer
    • Sgarbanti M, Remoli AL, Marsili G, Ridolfi B, Borsetti A, Perrotti E, et al.: IRF-1 is required for full NF-kappaB transcriptional activity at the human immunodeficiency virus type 1 long terminal repeat enhancer. J Virol 2008; 82: 3632-3641.
    • (2008) J Virol , vol.82 , pp. 3632-3641
    • Sgarbanti, M.1    Remoli, A.L.2    Marsili, G.3    Ridolfi, B.4    Borsetti, A.5    Perrotti, E.6
  • 20
    • 78049423723 scopus 로고    scopus 로고
    • Cohorts for the study of HIV-1-exposed but uninfected individuals: Benefits and limitations
    • Horton RE, McLaren PJ, Fowke K, Kimani J, and Ball TB: Cohorts for the study of HIV-1-exposed but uninfected individuals: Benefits and limitations. J Infect Dis 2010; 202: S377-S381.
    • (2010) J Infect Dis , vol.202
    • Horton, R.E.1    McLaren, P.J.2    Fowke, K.3    Kimani, J.4    Ball, T.B.5
  • 22
    • 79953804550 scopus 로고    scopus 로고
    • Evidence for the innate immune response as a correlate of protection in human immunodeficiency virus (HIV) -1 highly exposed seronegative subjects (HESN)
    • Tomescu C, Abdulhaqq S, and Montaner LJ: Evidence for the innate immune response as a correlate of protection in human immunodeficiency virus (HIV)-1 highly exposed seronegative subjects (HESN). Clin Exp Immunol 2011; 164: 158-169.
    • (2011) Clin Exp Immunol , vol.164 , pp. 158-169
    • Tomescu, C.1    Abdulhaqq, S.2    Montaner, L.J.3
  • 23
    • 8744309221 scopus 로고    scopus 로고
    • Novel interferon regulatory factor-1 polymorphisms in a Kenyan population revealed by complete gene sequencing
    • Ji H, Ball TB, Kimani J, and Plummer FA: Novel interferon regulatory factor-1 polymorphisms in a Kenyan population revealed by complete gene sequencing. J Hum Genet 2004; 49: 528-535.
    • (2004) J Hum Genet , vol.49 , pp. 528-535
    • Ji, H.1    Ball, T.B.2    Kimani, J.3    Plummer, F.A.4
  • 24
    • 34248531947 scopus 로고    scopus 로고
    • Polymorphisms in IRF-1 associated with resistance to HIV-1 infection in highly exposed uninfected Kenyan sex workers
    • Ball T, Ji H, Kimani J, McLaren P, Marlin C, Hill A, et al.: Polymorphisms in IRF-1 associated with resistance to HIV-1 infection in highly exposed uninfected Kenyan sex workers. AIDS 2007; 21: 1091.
    • (2007) AIDS , vol.21 , pp. 1091
    • Ball, T.1    Ji, H.2    Kimani, J.3    McLaren, P.4    Marlin, C.5    Hill, A.6
  • 25
    • 77950809872 scopus 로고    scopus 로고
    • Reduced HIV-1 long terminal repeat transcription in subjects with protective interferon regulatory factor-1 genotype: A potential mechanism mediating resistance to infection by HIV-1
    • Ji H, Ball TB, Ao Z, Kimani J, Yao X, and Plummer FA: Reduced HIV-1 long terminal repeat transcription in subjects with protective interferon regulatory factor-1 genotype: A potential mechanism mediating resistance to infection by HIV-1. Scand J Infect Dis 2010; 42: 389-394.
    • (2010) Scand J Infect Dis , vol.42 , pp. 389-394
    • Ji, H.1    Ball, T.B.2    Ao, Z.3    Kimani, J.4    Yao, X.5    Plummer, F.A.6
  • 26
    • 84879161120 scopus 로고    scopus 로고
    • Interferon regulatory factor 1 polymorphisms previously associated with reduced HIV susceptibility have no effect on HIV disease progression
    • Sivro A, McKinnon LR, Ji H, Kimani J, Jaoko W, Plummer FA, et al.: Interferon regulatory factor 1 polymorphisms previously associated with reduced HIV susceptibility have no effect on HIV disease progression. PLoS One 2013; 8: e66253.
    • (2013) PLoS One , vol.8
    • Sivro, A.1    McKinnon, L.R.2    Ji, H.3    Kimani, J.4    Jaoko, W.5    Plummer, F.A.6
  • 27
    • 79953124454 scopus 로고    scopus 로고
    • Epigenetic control of IRF1 responses in HIV-exposed seronegative versus HIV-susceptible individuals
    • Su R-C, Sivro A, Kimani J, Jaoko W, Plummer FA, and Ball TB: Epigenetic control of IRF1 responses in HIV-exposed seronegative versus HIV-susceptible individuals. Blood 2011; 117: 2649-2657.
    • (2011) Blood , vol.117 , pp. 2649-2657
    • Su, R.-C.1    Sivro, A.2    Kimani, J.3    Jaoko, W.4    Plummer, F.A.5    Ball, T.B.6
  • 28
    • 77249123298 scopus 로고    scopus 로고
    • Mechanisms of HIV latency: An emerging picture of complexity
    • Margolis DM: Mechanisms of HIV latency: An emerging picture of complexity. Curr HIV/AIDS Rep 2010; 7: 37-43.
    • (2010) Curr HIV/AIDS Rep , vol.7 , pp. 37-43
    • Margolis, D.M.1
  • 29
    • 55949083820 scopus 로고    scopus 로고
    • HIV rebounds from latently infected cells, rather than from continuing low-level replication
    • Joos B, Fischer M, Kuster H, Pillai SK, Wong JK, Boni J, et al.: HIV rebounds from latently infected cells, rather than from continuing low-level replication. Proc Natl Acad Sci USA 2008; 105: 16725-16730.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16725-16730
    • Joos, B.1    Fischer, M.2    Kuster, H.3    Pillai, S.K.4    Wong, J.K.5    Boni, J.6
  • 30
    • 0038579210 scopus 로고    scopus 로고
    • Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4 + T cells
    • Siliciano JD, Kajdas J, Finzi D, Quinn TC, Chadwick K, Margolick JB, et al.: Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4 + T cells. Nat Med 2003; 9: 727-728.
    • (2003) Nat Med , vol.9 , pp. 727-728
    • Siliciano, J.D.1    Kajdas, J.2    Finzi, D.3    Quinn, T.C.4    Chadwick, K.5    Margolick, J.B.6
  • 31
    • 16244412259 scopus 로고    scopus 로고
    • Host factors regulating postintegration latency of HIV
    • Williams SAF and Greene WC: Host factors regulating postintegration latency of HIV. Trends Microbiol 2005; 13: 137-139.
    • (2005) Trends Microbiol , vol.13 , pp. 137-139
    • Saf, W.1    Greene, W.C.2
  • 32
    • 14444273439 scopus 로고    scopus 로고
    • Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
    • Finzi D, Hermankova M, Pierson T, Carruth LM, Buck C, Chaisson RE, et al.: Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science 1997; 278: 1295-1300.
    • (1997) Science , vol.278 , pp. 1295-1300
    • Finzi, D.1    Hermankova, M.2    Pierson, T.3    Carruth, L.M.4    Buck, C.5    Chaisson, R.E.6
  • 33
    • 0030712305 scopus 로고    scopus 로고
    • Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
    • Wong JK: Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science 1997; 278: 1291-1295.
    • (1997) Science , vol.278 , pp. 1291-1295
    • Wong, J.K.1
  • 34
    • 9244249776 scopus 로고    scopus 로고
    • Expression of IFN regulatory factor family proteins in lymphocytes. Induction of Stat-1 and IFN consensus sequence binding protein expression by T cell activation
    • Nelson N, Kanno Y, Hong C, Contursi C, Fujita T, Fowlkes BJ, et al.: Expression of IFN regulatory factor family proteins in lymphocytes. Induction of Stat-1 and IFN consensus sequence binding protein expression by T cell activation. J Immunol 1996; 156: 3711-3720.
    • (1996) J Immunol , vol.156 , pp. 3711-3720
    • Nelson, N.1    Kanno, Y.2    Hong, C.3    Contursi, C.4    Fujita, T.5    Fowlkes, B.J.6
  • 35
    • 77953496625 scopus 로고    scopus 로고
    • The NF- B family of transcription factors and its regulation
    • Oeckinghaus A and Ghosh S: The NF- B family of transcription factors and its regulation. Cold Spring Harb Perspect Biol 2009; 1: a000034.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Oeckinghaus, A.1    Ghosh, S.2
  • 36
    • 0035061538 scopus 로고    scopus 로고
    • IRF family of transcription factors as regulators of host defense
    • Taniguchi T, Ogasawara K, Takaoka A, and Tanaka N: IRF family of transcription factors as regulators of host defense. Annu Rev Immunol 2001; 19: 623-655.
    • (2001) Annu Rev Immunol , vol.19 , pp. 623-655
    • Taniguchi, T.1    Ogasawara, K.2    Takaoka, A.3    Tanaka, N.4
  • 37
    • 28544437589 scopus 로고    scopus 로고
    • Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency
    • Munier S, Delcroix-Genete D, Carthagéna L, Gumez A, and Hazan U: Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency. Retrovirology 2005; 2: 73.
    • (2005) Retrovirology , vol.2 , pp. 73
    • Munier, S.1    Delcroix-Genete, D.2    Carthagéna, L.3    Gumez, A.4    Hazan, U.5
  • 39
    • 33845439862 scopus 로고    scopus 로고
    • IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features
    • Gabriele L, Fragale A, Borghi P, Sestili P, Stellacci E, Venditti M, et al.: IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features. J Leukoc Biol 2006; 80: 1500-1511.
    • (2006) J Leukoc Biol , vol.80 , pp. 1500-1511
    • Gabriele, L.1    Fragale, A.2    Borghi, P.3    Sestili, P.4    Stellacci, E.5    Venditti, M.6
  • 40
    • 44649098153 scopus 로고    scopus 로고
    • Not just sheer luck! Immune correlates of protection against HIV-1 infection
    • Piacentini L, Fenizia C, Naddeo V, and Clerici M: Not just sheer luck! Immune correlates of protection against HIV-1 infection. Vaccine 2008; 26: 3002-3007.
    • (2008) Vaccine , vol.26 , pp. 3002-3007
    • Piacentini, L.1    Fenizia, C.2    Naddeo, V.3    Clerici, M.4
  • 42
    • 64049087021 scopus 로고    scopus 로고
    • Lambda interferon inhibits human immunodeficiency virus type 1 infection of macrophages
    • Hou W, Wang X, Ye L, Zhou L, Yang Z-Q, Riedel E, et al.: Lambda interferon inhibits human immunodeficiency virus type 1 infection of macrophages. J Virol 2009; 83: 3834-3842.
    • (2009) J Virol , vol.83 , pp. 3834-3842
    • Hou, W.1    Wang, X.2    Ye, L.3    Zhou, L.4    Yang, Z.-Q.5    Riedel, E.6
  • 43
    • 0027278961 scopus 로고
    • Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells
    • Shirazi Y and Pitha PM: Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells. Virology 1993; 193: 303-312.
    • (1993) Virology , vol.193 , pp. 303-312
    • Shirazi, Y.1    Pitha, P.M.2
  • 44
    • 0024508421 scopus 로고
    • HIV replication can be blocked by recombinant human interferon beta
    • Michaelis B and Levy JA: HIV replication can be blocked by recombinant human interferon beta. AIDS 1989; 3: 27-31.
    • (1989) AIDS , vol.3 , pp. 27-31
    • Michaelis, B.1    Levy, J.A.2
  • 45
    • 77949409948 scopus 로고    scopus 로고
    • Targeting early infection to prevent HIV-1 mucosal transmission
    • Haase AT: Targeting early infection to prevent HIV-1 mucosal transmission. Nature 2010; 464: 217-223.
    • (2010) Nature , vol.464 , pp. 217-223
    • Haase, A.T.1
  • 47
    • 38949102301 scopus 로고    scopus 로고
    • Chronic innate immune activation as a cause of HIV-1 immunopathogenesis
    • Boasso A and Shearer GM: Chronic innate immune activation as a cause of HIV-1 immunopathogenesis. Clin Immunol 2008; 126: 235-242.
    • (2008) Clin Immunol , vol.126 , pp. 235-242
    • Boasso, A.1    Shearer, G.M.2
  • 48
    • 1242269845 scopus 로고    scopus 로고
    • Multiple effects of HIV-1 trans-activator protein on the pathogenesis of HIV-1 infection
    • Huigen M, Kamp W, and Nottet H: Multiple effects of HIV-1 trans-activator protein on the pathogenesis of HIV-1 infection. Eur J Clin Invest 2004; 34: 57-66.
    • (2004) Eur J Clin Invest , vol.34 , pp. 57-66
    • Huigen, M.1    Kamp, W.2    Nottet, H.3
  • 49
    • 33744819439 scopus 로고    scopus 로고
    • Intracellular HIV-1 Tat protein represses constitutive LMP2 transcription increasing proteasome activity by interfering with the binding of IRF-1 to STAT1
    • Remoli AL, Marsili G, Perrotti E, Gallerani E, Ilari R, Nappi F, et al.: Intracellular HIV-1 Tat protein represses constitutive LMP2 transcription increasing proteasome activity by interfering with the binding of IRF-1 to STAT1. Biochem J 2006; 396: 371-380.
    • (2006) Biochem J , vol.396 , pp. 371-380
    • Remoli, A.L.1    Marsili, G.2    Perrotti, E.3    Gallerani, E.4    Ilari, R.5    Nappi, F.6
  • 50
    • 0034329318 scopus 로고    scopus 로고
    • Mechanisms of HIV-associated lymphocyte apoptosis
    • Badley AD, Pilon AA, Landay A, and Lynch DH: Mechanisms of HIV-associated lymphocyte apoptosis. Blood 2000; 96: 2951-2964.
    • (2000) Blood , vol.96 , pp. 2951-2964
    • Badley, A.D.1    Pilon, A.A.2    Landay, A.3    Lynch, D.H.4
  • 51
    • 0343618494 scopus 로고    scopus 로고
    • The IFN regulatory factor family participates in regulation of Fas ligand gene expression in T cells
    • Chow WA, Fang JJ, and Yee J-K: The IFN regulatory factor family participates in regulation of Fas ligand gene expression in T cells. J Immunol 2000; 164: 3512-3518.
    • (2000) J Immunol , vol.164 , pp. 3512-3518
    • Chow, W.A.1    Fang, J.J.2    Yee, J.-K.3
  • 52
    • 77954576021 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 acts as a powerful adjuvant in tat DNA based vaccination
    • Castaldello A, Sgarbanti M, and Marsili G: Interferon regulatory factor-1 acts as a powerful adjuvant in tat DNA based vaccination. J Cell Physiol 2010; 224: 702-709.
    • (2010) J Cell Physiol , vol.224 , pp. 702-709
    • Castaldello, A.1    Sgarbanti, M.2    Marsili, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.