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Volumn 8, Issue 10, 2013, Pages

Inhibition of Intestinal Epithelial Apoptosis Improves Survival in a Murine Model of Radiation Combined Injury

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 6; PROTEIN BCL 2;

EID: 84886633305     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077203     Document Type: Article
Times cited : (11)

References (48)
  • 1
    • 33947131366 scopus 로고    scopus 로고
    • The 9-11 Commission's invitation to imagine: a pathophysiology-based approach to critical care of nuclear explosion victims
    • doi 10.1097/01.CCM.0000257328.31668.22
    • Manthous CA, Jackson WL Jr, (2007) The 9-11 Commission's invitation to imagine: a pathophysiology-based approach to critical care of nuclear explosion victims. Crit Care Med 35: 716-723 10.1097/01.CCM.0000257328.31668.22 [doi].
    • (2007) Crit Care Med , vol.35 , pp. 716-723
    • Manthous, C.A.1    Jackson Jr., W.L.2
  • 2
    • 0242444791 scopus 로고
    • Human and ecologic effects in Massachusetts of an assumed thermonuclear attack on the United States
    • Ervi FR, Glazier JB, Aronow S, Nathan D, Coleman R, et al. (1962) Human and ecologic effects in Massachusetts of an assumed thermonuclear attack on the United States. N Engl J Med 266: 1127-1137 10.1056/NEJM196205312662204 [doi].
    • (1962) N Engl J Med , vol.266 , pp. 1127-1137
    • Ervi, F.R.1    Glazier, J.B.2    Aronow, S.3    Nathan, D.4    Coleman, R.5
  • 3
    • 79952172464 scopus 로고    scopus 로고
    • National security staff interagency policy coordination subcommittee for preparedness and response to radiological and nuclear threats. Available: Accessed Aug 27
    • National security staff interagency policy coordination subcommittee for preparedness and response to radiological and nuclear threats. Planning guidance for response to a nuclear detonation. Available: http://www.epa.gov/radiation/docs/er/planning-guidance-for-response-to-n uclear-detonation-2-edition-final.pdf Accessed 2013 Aug 27.
    • (2013) Planning guidance for response to a nuclear detonation
  • 4
    • 44849121666 scopus 로고    scopus 로고
    • Medical countermeasures for radiation combined injury: radiation with burn, blast, trauma and/or sepsis. report of an NIAID Workshop, March 26-27, 2007
    • DiCarlo AL, Hatchett RJ, Kaminski JM, Ledney GD, Pellmar TC, et al. (2008) Medical countermeasures for radiation combined injury: radiation with burn, blast, trauma and/or sepsis. report of an NIAID Workshop, March 26-27, 2007. Radiat Res 169: 712-721.
    • (2008) Radiat Res , vol.169 , pp. 712-721
    • DiCarlo, A.L.1    Hatchett, R.J.2    Kaminski, J.M.3    Ledney, G.D.4    Pellmar, T.C.5
  • 5
    • 84872117343 scopus 로고    scopus 로고
    • Immune system phenotyping of radiation and radiation combined injury in outbred mice
    • Tajima G, Delisle AJ, Hoang K, O'Leary FM, Ikeda K, et al. (2013) Immune system phenotyping of radiation and radiation combined injury in outbred mice. Radiat Res 179: 101-112 10.1667/RR3120.1 [doi].
    • (2013) Radiat Res , vol.179 , pp. 101-112
    • Tajima, G.1    Delisle, A.J.2    Hoang, K.3    O'Leary, F.M.4    Ikeda, K.5
  • 6
    • 84868194038 scopus 로고    scopus 로고
    • Radiation combined with thermal injury induces immature myeloid cells
    • Mendoza AE, Neely CJ, Charles AG, Kartchner LB, Brickey WJ, et al. (2012) Radiation combined with thermal injury induces immature myeloid cells. Shock 38: 532-542 10.1097/SHK.0b013e31826c5b19 [doi].
    • (2012) Shock , vol.38 , pp. 532-542
    • Mendoza, A.E.1    Neely, C.J.2    Charles, A.G.3    Kartchner, L.B.4    Brickey, W.J.5
  • 7
    • 77649162874 scopus 로고    scopus 로고
    • Ghrelin as a novel therapy for radiation combined injury
    • Jacob A, Shah KG, Wu R, Wang P, (2010) Ghrelin as a novel therapy for radiation combined injury. Mol Med 16: 137-143 10.2119/molmed.2009.00154 [doi].
    • (2010) Mol Med , vol.16 , pp. 137-143
    • Jacob, A.1    Shah, K.G.2    Wu, R.3    Wang, P.4
  • 8
    • 77952003449 scopus 로고    scopus 로고
    • Radiation combined injury: overview of NIAID research
    • DiCarlo AL, Ramakrishnan N, Hatchett RJ, (2010) Radiation combined injury: overview of NIAID research. Health Phys 98: 863-867 10.1097/HP.0b013e3181a6ee32 [doi];00004032-201006000-00023 [pii].
    • (2010) Health Phys , vol.98 , pp. 863-867
    • DiCarlo, A.L.1    Ramakrishnan, N.2    Hatchett, R.J.3
  • 9
    • 44849125743 scopus 로고    scopus 로고
    • Progress in research on radiation combined injury in China
    • Zou Z, Sun H, Su Y, Cheng T, Luo C, (2008) Progress in research on radiation combined injury in China. Radiat Res 169: 722-729.
    • (2008) Radiat Res , vol.169 , pp. 722-729
    • Zou, Z.1    Sun, H.2    Su, Y.3    Cheng, T.4    Luo, C.5
  • 10
    • 0022445667 scopus 로고
    • Effect of radiation dose on the recovery of aerobic and anaerobic bacteria from mice
    • Brook I, Walker RI, Macvittie TJ, (1986) Effect of radiation dose on the recovery of aerobic and anaerobic bacteria from mice. Can J Microbiol 32: 719-722.
    • (1986) Can J Microbiol , vol.32 , pp. 719-722
    • Brook, I.1    Walker, R.I.2    Macvittie, T.J.3
  • 11
    • 0008429405 scopus 로고
    • Impairment of antimicrobial defense following total body irradiation of mice
    • Kaplan HS, Speck RS, Jawetz E, (1952) Impairment of antimicrobial defense following total body irradiation of mice. J Lab Clin Med 40: 682-691.
    • (1952) J Lab Clin Med , vol.40 , pp. 682-691
    • Kaplan, H.S.1    Speck, R.S.2    Jawetz, E.3
  • 12
    • 0141813471 scopus 로고    scopus 로고
    • Susceptibility of irradiated B6D2F1/J mice to Klebsiella pneumoniae administered intratracheally: a pulmonary infection model in an immunocompromised host
    • Keller CE, Elliott TB, Bentzel DE, Mog SR, Shoemaker MO, et al. (2003) Susceptibility of irradiated B6D2F1/J mice to Klebsiella pneumoniae administered intratracheally: a pulmonary infection model in an immunocompromised host. Comp Med 53: 397-403.
    • (2003) Comp Med , vol.53 , pp. 397-403
    • Keller, C.E.1    Elliott, T.B.2    Bentzel, D.E.3    Mog, S.R.4    Shoemaker, M.O.5
  • 13
    • 73249141375 scopus 로고    scopus 로고
    • Human ghrelin ameliorates organ injury and improves survival after radiation injury combined with severe sepsis
    • Shah KG, Wu R, Jacob A, Blau SA, Ji Y, et al. (2009) Human ghrelin ameliorates organ injury and improves survival after radiation injury combined with severe sepsis. Mol Med 15: 407-414 10.2119/molmed.2009.00100 [doi].
    • (2009) Mol Med , vol.15 , pp. 407-414
    • Shah, K.G.1    Wu, R.2    Jacob, A.3    Blau, S.A.4    Ji, Y.5
  • 14
    • 44849121666 scopus 로고    scopus 로고
    • Medical countermeasures for radiation combined injury: radiation with burn, blast, trauma and/or sepsis. report of an NIAID Workshop, March 26-27, 2007
    • DiCarlo AL, Hatchett RJ, Kaminski JM, Ledney GD, Pellmar TC, et al. (2008) Medical countermeasures for radiation combined injury: radiation with burn, blast, trauma and/or sepsis. report of an NIAID Workshop, March 26-27, 2007. Radiat Res 169: 712-721.
    • (2008) Radiat Res , vol.169 , pp. 712-721
    • DiCarlo, A.L.1    Hatchett, R.J.2    Kaminski, J.M.3    Ledney, G.D.4    Pellmar, T.C.5
  • 15
    • 37049001066 scopus 로고    scopus 로고
    • Hospitalizations and deaths caused by methicillin-resistant Staphylococcus aureus, United States, 1999-2005
    • Klein E, Smith DL, Laxminarayan R, (2007) Hospitalizations and deaths caused by methicillin-resistant Staphylococcus aureus, United States, 1999-2005. Emerg Infect Dis 13: 1840-1846.
    • (2007) Emerg Infect Dis , vol.13 , pp. 1840-1846
    • Klein, E.1    Smith, D.L.2    Laxminarayan, R.3
  • 16
    • 33947595160 scopus 로고    scopus 로고
    • Comparison of mortality risk associated with bacteremia due to methicillin-resistant and methicillin-susceptible Staphylococcus aureus
    • Shurland S, Zhan M, Bradham DD, Roghmann MC, (2007) Comparison of mortality risk associated with bacteremia due to methicillin-resistant and methicillin-susceptible Staphylococcus aureus. Infect Control Hosp Epidemiol 28: 273-279 ICHE2005340 [pii];10.1086/512627 [doi].
    • (2007) Infect Control Hosp Epidemiol , vol.28 , pp. 273-279
    • Shurland, S.1    Zhan, M.2    Bradham, D.D.3    Roghmann, M.C.4
  • 17
    • 34748831860 scopus 로고    scopus 로고
    • Epidemiology and economic impact of meticillin-resistant Staphylococcus aureus: review and analysis of the literature
    • 2594 [pii]
    • Shorr AF (2007) Epidemiology and economic impact of meticillin-resistant Staphylococcus aureus: review and analysis of the literature. Pharmacoeconomics 25: 751-768. 2594 [pii].
    • (2007) Pharmacoeconomics , vol.25 , pp. 751-768
    • Shorr, A.F.1
  • 18
    • 0038029714 scopus 로고    scopus 로고
    • Treatment of Acute Radiation Sickness
    • In: Gusev IA, Guskova AK, Mettler FA, editors, Taylor & Francis, Inc
    • Mettler FA, Guskova AK (2001) Treatment of Acute Radiation Sickness. In: Gusev IA, Guskova AK, Mettler FA, editors. Medical Management of Radiation Accidents. Taylor & Francis, Inc. 53-68.
    • (2001) Medical Management of Radiation Accidents , pp. 53-68
    • Mettler, F.A.1    Guskova, A.K.2
  • 19
    • 1542513848 scopus 로고    scopus 로고
    • Management of postirradiation infection: lessons learned from animal models
    • Brook I, Elliott TB, Ledney GD, Shoemaker MO, Knudson GB, (2004) Management of postirradiation infection: lessons learned from animal models. Mil Med 169: 194-197.
    • (2004) Mil Med , vol.169 , pp. 194-197
    • Brook, I.1    Elliott, T.B.2    Ledney, G.D.3    Shoemaker, M.O.4    Knudson, G.B.5
  • 20
    • 0032948512 scopus 로고    scopus 로고
    • Bcl-2 inhibits ischemia-reperfusion-induced apoptosis in the intestinal epithelium of transgenic mice
    • Coopersmith CM, O'Donnell D, Gordon JI, (1999) Bcl-2 inhibits ischemia-reperfusion-induced apoptosis in the intestinal epithelium of transgenic mice. Am J Physiol 276: G677-G686.
    • (1999) Am J Physiol , vol.276
    • Coopersmith, C.M.1    O'Donnell, D.2    Gordon, J.I.3
  • 21
    • 84862753094 scopus 로고    scopus 로고
    • Mechanisms of methicillin-resistant Staphylococcus aureus pneumonia-induced intestinal epithelial apoptosis
    • Perrone EE, Jung E, Breed E, Dominguez JA, Liang Z, et al. (2012) Mechanisms of methicillin-resistant Staphylococcus aureus pneumonia-induced intestinal epithelial apoptosis. Shock 38: 68-75 10.1097/SHK.0b013e318259abdb [doi].
    • (2012) Shock , vol.38 , pp. 68-75
    • Perrone, E.E.1    Jung, E.2    Breed, E.3    Dominguez, J.A.4    Liang, Z.5
  • 22
    • 83655191969 scopus 로고    scopus 로고
    • Cecal ligation and puncture followed by methicillin-resistant Staphylococcus aureus pneumonia increases mortality in mice and blunts production of local and systemic cytokines
    • Jung E, Perrone EE, Liang Z, Breed ER, Dominguez JA, et al. (2012) Cecal ligation and puncture followed by methicillin-resistant Staphylococcus aureus pneumonia increases mortality in mice and blunts production of local and systemic cytokines. Shock 37: 85-94 10.1097/SHK.0b013e3182360faf [doi].
    • (2012) Shock , vol.37 , pp. 85-94
    • Jung, E.1    Perrone, E.E.2    Liang, Z.3    Breed, E.R.4    Dominguez, J.A.5
  • 23
    • 77249138225 scopus 로고    scopus 로고
    • Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis
    • Fox AC, Robertson CM, Belt B, Clark AT, Chang KC, et al. (2010) Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis. Crit Care Med 38: 886-893 10.1097/CCM.0b013e3181c8fdb1 [doi].
    • (2010) Crit Care Med , vol.38 , pp. 886-893
    • Fox, A.C.1    Robertson, C.M.2    Belt, B.3    Clark, A.T.4    Chang, K.C.5
  • 24
    • 56449129255 scopus 로고    scopus 로고
    • Neutrophil depletion causes a fatal defect in murine pulmonary Staphylococcus aureus clearance
    • Robertson CM, Perrone EE, McConnell KW, Dunne WM, Boody B, et al. (2008) Neutrophil depletion causes a fatal defect in murine pulmonary Staphylococcus aureus clearance. J Surg Res 150: 278-285 S0022-4804(08)00090-5 [pii];10.1016/j.jss.2008.02.009 [doi].
    • (2008) J Surg Res , vol.150 , pp. 278-285
    • Robertson, C.M.1    Perrone, E.E.2    McConnell, K.W.3    Dunne, W.M.4    Boody, B.5
  • 25
    • 9644252946 scopus 로고    scopus 로고
    • Impact of the indigenous flora in animal models of shock and sepsis
    • Wells CL, Hess DJ, Erlandsen SL, (2004) Impact of the indigenous flora in animal models of shock and sepsis. Shock 22: 562-568.
    • (2004) Shock , vol.22 , pp. 562-568
    • Wells, C.L.1    Hess, D.J.2    Erlandsen, S.L.3
  • 26
    • 84869051728 scopus 로고    scopus 로고
    • Intestine-specific Mttp deletion decreases mortality and prevents sepsis-induced intestinal injury in a murine model of Pseudomonas aeruginosa pneumonia
    • Dominguez JA, Xie Y, Dunne WM, Yoseph BP, Burd EM, et al. (2012) Intestine-specific Mttp deletion decreases mortality and prevents sepsis-induced intestinal injury in a murine model of Pseudomonas aeruginosa pneumonia. PLoS ONE 7: e49159 10.1371/journal.pone.0049159 [doi];PONE-D-12-07223 [pii].
    • (2012) PLoS ONE , vol.7
    • Dominguez, J.A.1    Xie, Y.2    Dunne, W.M.3    Yoseph, B.P.4    Burd, E.M.5
  • 27
    • 84868207549 scopus 로고    scopus 로고
    • The endogenous bacteria alter gut epithelial apoptosis and decrease mortality following Pseudomonas aeruginosa pneumonia
    • Fox AC, McConnell KW, Yoseph BP, Breed E, Liang Z, et al. (2012) The endogenous bacteria alter gut epithelial apoptosis and decrease mortality following Pseudomonas aeruginosa pneumonia. Shock 38: 508-514 10.1097/SHK.0b013e31826e47e8 [doi].
    • (2012) Shock , vol.38 , pp. 508-514
    • Fox, A.C.1    McConnell, K.W.2    Yoseph, B.P.3    Breed, E.4    Liang, Z.5
  • 28
    • 34247526931 scopus 로고    scopus 로고
    • Epithelial apoptosis in mechanistically distinct methods of injury in the murine small intestine
    • Vyas D, Robertson CM, Stromberg PE, Martin JR, Dunne WM, et al. (2007) Epithelial apoptosis in mechanistically distinct methods of injury in the murine small intestine. Histol Histopathol 22: 623-630.
    • (2007) Histol Histopathol , vol.22 , pp. 623-630
    • Vyas, D.1    Robertson, C.M.2    Stromberg, P.E.3    Martin, J.R.4    Dunne, W.M.5
  • 29
    • 67649306715 scopus 로고    scopus 로고
    • CD4+ lymphocytes control gut epithelial apoptosis and mediate survival in sepsis
    • Stromberg PE, Woolsey CA, Clark AT, Clark JA, Turnbull IR, et al. (2009) CD4+ lymphocytes control gut epithelial apoptosis and mediate survival in sepsis. FASEB J 23: 1817-1825.
    • (2009) FASEB J , vol.23 , pp. 1817-1825
    • Stromberg, P.E.1    Woolsey, C.A.2    Clark, A.T.3    Clark, J.A.4    Turnbull, I.R.5
  • 30
    • 51549100691 scopus 로고    scopus 로고
    • Epidermal growth factor treatment decreases mortality and is associated with improved gut integrity in sepsis
    • Clark JA, Clark AT, Hotchkiss RS, Buchman TG, Coopersmith CM, (2008) Epidermal growth factor treatment decreases mortality and is associated with improved gut integrity in sepsis. Shock 30: 36-42.
    • (2008) Shock , vol.30 , pp. 36-42
    • Clark, J.A.1    Clark, A.T.2    Hotchkiss, R.S.3    Buchman, T.G.4    Coopersmith, C.M.5
  • 31
    • 80052967969 scopus 로고    scopus 로고
    • Epidermal Growth Factor Improves Survival and Prevents Intestinal Injury in a Murine Model of Pseudomonas Aeruginosa Pneumonia
    • 10.1097/SHK.0b013e31822793c4 [doi]
    • Dominguez JA, Vithayathil PJ, Khailova L, Lawrance CP, Samocha AJ, et al. (2011) Epidermal Growth Factor Improves Survival and Prevents Intestinal Injury in a Murine Model of Pseudomonas Aeruginosa Pneumonia. Shock. 10.1097/SHK.0b013e31822793c4 [doi].
    • (2011) Shock
    • Dominguez, J.A.1    Vithayathil, P.J.2    Khailova, L.3    Lawrance, C.P.4    Samocha, A.J.5
  • 32
    • 84858115999 scopus 로고    scopus 로고
    • Medical effects and risks of exposure to ionising radiation
    • Mettler FA, (2012) Medical effects and risks of exposure to ionising radiation. J Radiol Prot 32: N9-N13 S0952-4746(12)22330-4 [pii];10.1088/0952-4746/32/1/N9 [doi].
    • (2012) J Radiol Prot , vol.32
    • Mettler, F.A.1
  • 33
    • 1642580868 scopus 로고    scopus 로고
    • Radiation, the ideal cytotoxic agent for studying the cell biology of tissues such as the small intestine
    • Potten CS, (2004) Radiation, the ideal cytotoxic agent for studying the cell biology of tissues such as the small intestine. Radiat Res 161: 123-136.
    • (2004) Radiat Res , vol.161 , pp. 123-136
    • Potten, C.S.1
  • 34
    • 33646453766 scopus 로고    scopus 로고
    • Organ-specific gene expressions in C57BL/6 mice after exposure to low-dose radiation
    • Lee WJ, Majumder ZR, Jeoung DI, Lee HJ, Kim SH, et al. (2006) Organ-specific gene expressions in C57BL/6 mice after exposure to low-dose radiation. Radiat Res 165: 562-569 RR3549 [pii];10.1667/RR3549.1 [doi].
    • (2006) Radiat Res , vol.165 , pp. 562-569
    • Lee, W.J.1    Majumder, Z.R.2    Jeoung, D.I.3    Lee, H.J.4    Kim, S.H.5
  • 35
    • 33947242458 scopus 로고    scopus 로고
    • Accidental or intentional exposure to ionizing radiation: biodosimetry and treatment options
    • Chao NJ, (2007) Accidental or intentional exposure to ionizing radiation: biodosimetry and treatment options. Exp Hematol 35: 24-27 S0301-472X(07)00011-2 [pii];10.1016/j.exphem.2007.01.008 [doi].
    • (2007) Exp Hematol , vol.35 , pp. 24-27
    • Chao, N.J.1
  • 36
    • 66749164669 scopus 로고    scopus 로고
    • The sepsis seesaw: tilting toward immunosuppression
    • Hotchkiss RS, Coopersmith CM, McDunn JE, Ferguson TA, (2009) The sepsis seesaw: tilting toward immunosuppression. Nat Med 15: 496-497 nm0509-496 [pii];10.1038/nm0509-496 [doi].
    • (2009) Nat Med , vol.15 , pp. 496-497
    • Hotchkiss, R.S.1    Coopersmith, C.M.2    McDunn, J.E.3    Ferguson, T.A.4
  • 37
    • 77954183132 scopus 로고    scopus 로고
    • Immunotherapy for sepsis-a new approach against an ancient foe
    • Hotchkiss RS, Opal S, (2010) Immunotherapy for sepsis-a new approach against an ancient foe. N Engl J Med 363: 87-89 363/1/87 [pii];10.1056/NEJMcibr1004371 [doi].
    • (2010) N Engl J Med , vol.363 , pp. 87-89
    • Hotchkiss, R.S.1    Opal, S.2
  • 38
    • 0031110570 scopus 로고    scopus 로고
    • Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway
    • Hiramatsu M, Hotchkiss RS, Karl IE, Buchman TG, (1997) Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway. Shock 7: 247-253.
    • (1997) Shock , vol.7 , pp. 247-253
    • Hiramatsu, M.1    Hotchkiss, R.S.2    Karl, I.E.3    Buchman, T.G.4
  • 39
    • 0028047723 scopus 로고
    • The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice
    • Merritt AJ, Potten CS, Kemp CJ, Hickman JA, Balmain A, et al. (1994) The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res 54: 614-617.
    • (1994) Cancer Res , vol.54 , pp. 614-617
    • Merritt, A.J.1    Potten, C.S.2    Kemp, C.J.3    Hickman, J.A.4    Balmain, A.5
  • 40
    • 34548682085 scopus 로고    scopus 로고
    • Intestinal crosstalk: a new paradigm for understanding the gut as the "motor" of critical illness
    • Clark JA, Coopersmith CM, (2007) Intestinal crosstalk: a new paradigm for understanding the gut as the "motor" of critical illness. Shock 28: 384-393.
    • (2007) Shock , vol.28 , pp. 384-393
    • Clark, J.A.1    Coopersmith, C.M.2
  • 41
    • 0022644165 scopus 로고
    • Multiple-organ-failure syndrome. The gastrointestinal tract: the "motor" of MOF
    • Carrico CJ, Meakins JL, Marshall JC, Fry D, Maier RV, (1986) Multiple-organ-failure syndrome. The gastrointestinal tract: the "motor" of MOF. Arch Surg 121: 196-208.
    • (1986) Arch Surg , vol.121 , pp. 196-208
    • Carrico, C.J.1    Meakins, J.L.2    Marshall, J.C.3    Fry, D.4    Maier, R.V.5
  • 43
    • 45449103626 scopus 로고    scopus 로고
    • Modulation of apoptosis of eckol against ionizing radiation in mice
    • Park E, Lee NH, Joo HG, Jee Y, (2008) Modulation of apoptosis of eckol against ionizing radiation in mice. Biochem Biophys Res Commun 372: 792-797.
    • (2008) Biochem Biophys Res Commun , vol.372 , pp. 792-797
    • Park, E.1    Lee, N.H.2    Joo, H.G.3    Jee, Y.4
  • 44
    • 85047690934 scopus 로고    scopus 로고
    • Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation
    • Tessner TG, Muhale F, Riehl TE, Anant S, Stenson WF, (2004) Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation. J Clin Invest 114: 1676-1685.
    • (2004) J Clin Invest , vol.114 , pp. 1676-1685
    • Tessner, T.G.1    Muhale, F.2    Riehl, T.E.3    Anant, S.4    Stenson, W.F.5
  • 45
    • 69749088080 scopus 로고    scopus 로고
    • Enterocyte-specific epidermal growth factor prevents barrier dysfunction and improves mortality in murine peritonitis
    • Clark JA, Gan H, Samocha AJ, Fox AC, Buchman TG, et al. (2009) Enterocyte-specific epidermal growth factor prevents barrier dysfunction and improves mortality in murine peritonitis. Am J Physiol Gastrointest Liver Physiol 297: G471-G479.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.297
    • Clark, J.A.1    Gan, H.2    Samocha, A.J.3    Fox, A.C.4    Buchman, T.G.5
  • 46
    • 80052967969 scopus 로고    scopus 로고
    • Epidermal growth factor improves survival and prevents intestinal injury in a murine model of pseudomonas aeruginosa pneumonia
    • Dominguez JA, Vithayathil PJ, Khailova L, Lawrance CP, Samocha AJ, et al. (2011) Epidermal growth factor improves survival and prevents intestinal injury in a murine model of pseudomonas aeruginosa pneumonia. Shock 36: 381-389 10.1097/SHK.0b013e31822793c4 [doi].
    • (2011) Shock , vol.36 , pp. 381-389
    • Dominguez, J.A.1    Vithayathil, P.J.2    Khailova, L.3    Lawrance, C.P.4    Samocha, A.J.5
  • 47
    • 84861364136 scopus 로고    scopus 로고
    • Animal models and medical countermeasures development for radiation-induced lung damage: report from an NIAID Workshop
    • Williams JP, Jackson IL, Shah JR, Czarniecki CW, Maidment BW, et al. (2012) Animal models and medical countermeasures development for radiation-induced lung damage: report from an NIAID Workshop. Radiat Res 177: e0025-e0039 10.1667/RROL04.1 [pii].
    • (2012) Radiat Res , vol.177
    • Williams, J.P.1    Jackson, I.L.2    Shah, J.R.3    Czarniecki, C.W.4    Maidment, B.W.5
  • 48
    • 84867903811 scopus 로고    scopus 로고
    • Sepsis chronically in MARS: systemic cytokine responses are always mixed regardless of the outcome, magnitude, or phase of sepsis
    • Osuchowski MF, Craciun F, Weixelbaumer KM, Duffy ER, Remick DG, (2012) Sepsis chronically in MARS: systemic cytokine responses are always mixed regardless of the outcome, magnitude, or phase of sepsis. J Immunol 189: 4648-4656 jimmunol.1201806 [pii];10.4049/jimmunol.1201806 [doi].
    • (2012) J Immunol , vol.189 , pp. 4648-4656
    • Osuchowski, M.F.1    Craciun, F.2    Weixelbaumer, K.M.3    Duffy, E.R.4    Remick, D.G.5


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