Decreased vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) function in knockout mice affects aging of dopaminergic systems

Neuropharmacology

Volumn 76, Issue PART A, 2014, Pages 146-155

  Hall, F S ^a   Itokawa, K ^b   Schmitt, A ^c   Moessner, R ^c   Sora, I ^d   Lesch, K P ^c   Uhl, G R ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Aging; Amphetamine; Cocaine; Dopamine; Gene knockout; Transgenic mice

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 5 HYDROXYINDOLEACETIC ACID; BRAIN MONOAMINE; COCAINE; DOPAMINE; DOPAMINE TRANSPORTER; HOMOVANILLIC ACID; SEROTONIN; VESICULAR MONOAMINE TRANSPORTER 2;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; CORPUS STRIATUM; CYTOSOL; DAT GENE; DOPAMINE METABOLISM; DOPAMINERGIC SYSTEM; GENE; GENE DELETION; HETEROZYGOSITY; KNOCKOUT MOUSE; LOCOMOTION; MESENCEPHALON; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; VMAT2 GENE; WILD TYPE;

AGING; AMPHETAMINE; COCAINE; DOPAMINE; GENE KNOCKOUT; TRANSGENIC MICE;

AGING; AMPHETAMINE; ANIMALS; COCAINE; CORPUS STRIATUM; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINERGIC NEURONS; MESENCEPHALON; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; VESICULAR MONOAMINE TRANSPORT PROTEINS;

EID: 84886592899     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.07.031     Document Type: Article

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