Normal and drug-induced locomotor behavior in aging: Comparison to evoked DA release and tissue content in Fischer 344 rats

Brain Research

Volumn 797, Issue 1, 1998, Pages 42-54

  Hebert, Meleik A ^a   Gerhardt, Greg A ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Aging; Dopamine; In vivo electrochemisty; Locomotion; Mesolimbic; Nigrostriatal

Indexed keywords

POTASSIUM;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DOPAMINE RELEASE; ELECTROCHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMBIC CORTEX; LOCOMOTION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA;

3,4-DIHYDROXYPHENYLACETIC ACID; ADRENERGIC UPTAKE INHIBITORS; AGING; ANIMALS; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CITALOPRAM; CORPUS STRIATUM; DESIPRAMINE; DOPAMINE; DOPAMINE UPTAKE INHIBITORS; ELECTROCHEMISTRY; HABITUATION, PSYCHOPHYSIOLOGIC; LIMBIC SYSTEM; LOCOMOTION; MALE; NOMIFENSINE; NUCLEUS ACCUMBENS; POTASSIUM; RATS; RATS, INBRED F344; SEROTONIN UPTAKE INHIBITORS; SUBSTANTIA NIGRA;

EID: 0032557869     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00370-9     Document Type: Article

References (91)

1. Adolfsson R., Gottfries C.G., Roos B.E., Winblad B. Postmortem distribution of dopamine and homovanillic acid in human brain, variations related to age, and a review of the literature. J. Neural Transm. 45:1979;81-105.
2. Allard P., Marcusson J.O. Age-correlated loss of dopamine uptake sites labeled with [3H]GBR-12935 in human putamen. Neurobiol. Aging. 10:1989;661-664.
3. Altar C.A., Marshall J.F. Neostriatal dopamine uptake and reversal of age-related movement disorders with dopamine-uptake inhibitors. Ann. New York Acad. Sci. 515:1988;343-354.
4. Ammassari-Teule M., Fagioli S., Rossi-Arnaud C. Radial maze performance and open-field behaviours in aged C57BL/6 mice: further evidence for preserved cognitive abilities during senescence. Physiol. Behav. 55:1994;341-345.
5. Barrio J.R., Huang S.C., Phelps M.E. Biological imaging and the molecular basis of dopaminergic diseases. Biochem. Pharmacol. 54:1997;341-348.
6. Bennett D.A., Beckett L.A., Murray A.M., Shannon K.M., Goetz C.G., Pilgrim D.M., Evans D.A. Prevalence of parkinsonian signs and associated mortality in a community population of older people. New Engl. J. Med. 334:1996;71-76.
7. Bergman J., Madras B.K., Johnson S.E., Spealman R.D. Effects of cocaine and related drugs in nonhuman primates: III. Self-administration by squirrel monkeys. J. Pharmacol. Exp. Ther. 251:1989;150-155.
8. Bernheimer H., Birkmayer W., Hornykiewicz O., Jellinger K., Seitelberger F. Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations. J. Neurol. Sci. 20:1973;415-455.
9. J.E. Birren, J.M. Woods, M.V. Williams, Speed of behavior as indicator of age changes and the integrity of the nervous system, in: F. Hoffmeister, C. Muller (Eds.), Brain Function and Old Age, Springer, New York, 1979.
10. Bunsey M.D., Sanberg P.R. The topography of the locomotor effects of haloperidol and domperidone. Behav. Brain Res. 19:1986;147-152.
11. Burwell R.D., Gallagher M. A longitudinal study of reaction time performance in Long-Evans rats. Neurobiol. Aging. 14:1993;57-64.
12. Carlsson A., Winblad B. Influence of age and time interval between death and autopsy on dopamine and 3-methoxytyramine levels in human basal ganglia. J. Neural Transm. 38:1976;271-276.
13. Cass W.A., Zahniser N.R., Flach K.A., Gerhardt G.A. Clearance of exogenous dopamine in rat dorsal striatum and nucleus accumbens: role of metabolism and effects of locally applied uptake inhibitors. J. Neurochem. 61:1993;2269-2278.
14. Cerbone A., Sadile A.G. Behavioral habituation to spatial novelty: interference and noninterference studies. Neurosci. Biobehav. Rev. 18:1994;497-518.
15. de Keyser J., Ebinger G., Vauquelin G. Age-related changes in the human nigrostriatal dopaminergic system. Ann. Neurol. 27:1990;157-161.
16. I.F. de Koning-Verest, D.L. Knook, O.L. Wolthius, Behavioral and biochemical correlates of aging in rats, in: D.G. Stein (Ed.), The psychobiology of Aging: Problems and Perspectives, Elsevier, Amsterdam, 1980, pp. 177-199.
17. Emerich D.F., McDermott P., Krueger P., Banks M., Zhao J., Marszalkowski J., Frydel B., Winn S.R., Sanberg P.R. Locomotion of aged rats: relationship to neurochemical but not morphological changes in nigrostriatal dopaminergic neurons. Brain Res. Bull. 32:1993;477-486.
18. Fielding S., Szewczak M.R. Pharmacology of nomifensine: a review of animal studies. J. Clin. Psychiatry. 45:1984;12-20.
19. Finch C.E. Catecholamine metabolism in the brains of ageing male mice. Brain Res. 52:1973;261-276.
20. Fink J.S., Smith G.P. Mesolimbicocortical dopamine terminal fields are necessary for normal locomotor and investigatory exploration in rats. Brain Res. 199:1980;359-384.
21. Friedemann M., Gerhardt G.A. In vivo electrochemical studies of the effects of N-methyl-D-aspartate (NMDA) on dopamine nerve terminals in the neostriatum of the anesthetized rat. Proc. West. Pharmacol. Soc. 32:1989;143-147.
22. Friedemann M.N. In vivo electrochemical studies of dopamine diffusion and clearance in the striatum of young and aged Fischer 344 rats. Age. 15:1992;23-28.
23. Friedemann M.N., Gerhardt G.A. Regional effects of aging on dopaminergic function in the Fischer 344 rat. Neurobiol. Aging. 13:1992;325-332.
24. Gage F.H., Bjorklund A., Stenevi U., Dunnett S.B. Intracerebral grafting of neuronal cell suspensions: VIII. Survival and growth of implants of nigral and septal cell suspensions in intact brains of aged rats. Acta Physiol. Scand. Suppl. 522:1983;67-75.
25. Gage F.H., Dunnett S.B., Bjorklund A. Spatial learning and motor deficits in aged rats. Neurobiol. Aging. 5:1984;43-48.
26. Gallagher M., Pelleymounter M.A. An age-related spatial learning deficit: choline uptake distinguishes 'impaired' and 'unimpaired' rats. Neurobiol. Aging. 9:1988;363-369.
27. Gallagher M., Burwell R.D. Relationship of age-related decline across several behavioral domains. Neurobiol. Aging. 10:1989;691-708.
28. Gerhardt G.A., Oke A.F., Nagy G., Moghaddam B., Adams R.N. Nafion-coated electrodes with high selectivity for CNS electrochemistry. Brain Res. 290:1984;390-395.
29. Gerhardt G.A., Rose G.M., Hoffer B.J. Release of monoamines from striatum of rat and mouse evoked by local application of potassium: evaluation of a new in vivo electrochemical technique. J. Neurochem. 46:1986;842-850.
30. Gerhardt G.A., Cass W.A., Henson M., Zhang Z., Ovadia A., Hoffer B.J., Gash D.M. Age-related changes in potassium-evoked overflow of dopamine in the striatum of the rhesus monkey. Neurobiol. Aging. 16:1995;939-946.
31. Gerhardt G.A., Cass W.A., Hudson J., Henson M., Zhang Z., Ovadia A., Hoffer B.J., Gash D.M. In vivo electrochemical studies of dopamine overflow and clearance in the striatum of normal and MPTP-treated rhesus monkeys. J. Neurochem. 66:1996;579-588.
32. Goldman-Rakic P.S., Brown R.M. Regional changes of monoamines in cerebral cortex and subcortical structures of aging rhesus monkeys. Neuroscience. 6:1981;177-187.
33. Goudsmit E., Feenstra M.G.P., Swaab D.F. Central monoamine metabolism in the male Brown-Norway rat in relation to aging and testosterone. Brain Res. Bull. 25:1990;755-763.
34. Gozlan H., Daval G., Verge D., Spampinato U., Fattaccini C.M., Gallissot M.C., el Mestikawy S., Hamon M. Aging associated changes in serotoninergic and dopaminergic pre- and postsynaptic neurochemical markers in the rat brain. Neurobiol. Aging. 11:1990;437-449.
35. Gratton A., Hoffer B.J., Gerhardt G.A. In vivo electrochemical studies of monoamine release in the medial prefrontal cortex of the rat. Neuroscience. 29:1989;57-64.
36. Hall M., Hoffer B., Gerhardt G. Rapid and sensitive determination of catecholamines in small tissue samples by high pressure liquid chromatography coupled with dual-electrode coulometric electrochemical detection. LC-GC. 7:1996;258-265.
37. Haycock J.W., White W.F., McGaugh J.L., Cotman C.W. Enhanced stimulus-secretion coupling from brains of aged mice. Exp. Neurol. 57:1977;873-882.
38. Hebert M.A., van Horne C.G., Hoffer B.J., Gerhardt G.A. Functional effects of GDNF in normal rat striatum: presynaptic studies using in vivo electrochemistry and microdialysis. J. Pharmacol. Exp. Ther. 279:1996;1181-1190.
39. Hebert M.A., Gerhardt G.A. Behavioral and neurochemical effects of intranigral administration of glial cell line-derived neurotrophic factor on aged Fischer 344 rats. J. Pharmacol. Exp. Ther. 282:1997;760-768.
40. Hornykiewicz O. Parkinson's disease: from brain homogenate to treatment. Fed. Proc. 32:1973;183-190.
41. Hornykiewicz O., Kish S.J. Biochemical pathophysiology of Parkinson's disease. Adv. Neurol. 45:1987;19-34.
42. Hornykiewicz O. Parkinson's disease and the adaptive capacity of the nigrostriatal dopamine system: possible neurochemical mechanisms. Adv. Neurol. 60:1993;140-147.
43. Hudson J., Granholm A.C., Gerhardt G.A., Henry M.A., Hoffman A., Biddle P., Leela N.S., Mackerlova L., Lile J.D., Collins F.et al. Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo. Brain Res. Bull. 36:1995;425-432.
44. Ingram D.K., Joseph J.A., Spangler E.L., Roberts D., Hengemihle J., Fanelli R.J. Chronic nimodipine treatment in aged rats: analysis of motor and cognitive effects and muscarinic-induced striatal dopamine release. Neurobiol. Aging. 15:1994;55-61.
45. Janicke B., Schulze G., Coper H. Motor performance achievements in rats of different ages. Exp. Gerontol. 18:1983;393-407.
46. Joseph J.A., Berger R.E., Engel B.T., Roth G.S. Age-related changes in the nigrostriatum: a behavioral and biochemical analysis. J. Gerontol. 33:1978;643-649.
47. Joseph J.A., Bartus R.T., Clody D., Morgan D., Finch C., Beer B., Sesack S. Psychomotor performance in the senescent rodent: reduction of deficits via striatal dopamine receptor upregulation. Neurobiol. Aging. 4:1983;313-319.
48. Joseph J.A., Roth G.S. Upregulation of striatal dopamine receptors and improvement of motor performance in senescence. Ann. New York Acad. Sci. 515:1988;355-362.
49. Kametani H., Iijima S., Spangler E.L., Ingram D.K., Joseph J.A. In vivo assessment of striatal dopamine release in the aged male Fischer 344 rat. Neurobiol. Aging. 16:1995;639-646.
50. Kelley A.E., Winnock M., Stinus L. Amphetamine, apomorphine and investigatory behavior in the rat: analysis of the structure and pattern of responses. Psychopharmacology. 88:1986;66-74.
51. Kish S.J., Shannak K., Rajput A., Deck J.H., Hornykiewicz O. Aging produces a specific pattern of striatal dopamine loss: implications for the etiology of idiopathic Parkinson's disease. J. Neurochem. 58:1992;642-648.
52. Lowy A.D., Ingram D., Olton D.S., Waller S., Reynolds M., London E. Discrimination learning requiring different memory components in rats: age and neurochemical comparisons. Behav. Neurosci. 99:1985;638-651.
53. Machado A., Cano J., Santiago M. The change with age in biogenic amines and their metabolites in the striatum of the rat. Arch. Gerontol. Geriatr. 5:1986;333-342.
54. MacRae P.G., Spirduso W.W., Wilcox R.E. Reaction time and nigrostriatal dopamine function: the effects of age and practice. Brain Res. 451:1988;139-146.
55. Maj J., Kapturkiewicz Z., Michaluk J. Central action of nomifensine. Pol. J. Pharmacol. Pharm. 28:1976;557-562.
56. Makman M.H., Ahn H.S., Thal L.J., Sharpless N.S., Dvorkin B., Horowitz S.G., Rosenfeld M. Evidence for selective loss of brain dopamine- and histamine-stimulated adenylate cyclase activities in rabbits with aging. Brain Res. 192:1980;177-183.
57. Marshall J.F., Berrios N. Movement disorders of aged rats: reversal by dopamine receptor stimulation. Science. 206:1979;477-479.
58. Marshall J.F. Sensorimotor disturbances in the aging rodent. J. Gerontol. 37:1982;548-554.
59. Marshall J.F., Altar C.A. Striatal dopamine uptake and swim performance of the aged rat. Brain Res. 379:1986;112-117.
60. E.J. Masoro, Animal models in aging research, in: E.L. Schneider, J.E. Rowe (Eds.), The Handbook of the Biology of Aging, 3rd edn., Academic Press, San Diego, 1990, pp. 72-94.
61. McNeill T.H., Koek L.L. Differential effects of advancing age on neurotransmitter cell loss in the substantia nigra and striatum of C57BL/6N mice. Brain Res. 521:1990;107-117.
62. Moretti A., Carfagna N., Trunzo F. Effect of aging on monoamines and their metabolites in the rat brain. Neurochem. Res. 12:1987;1035-1039.
63. Morgan D.G., May P.C., Finch C.E. Dopamine and serotonin systems in human and rodent brain: effects of age and neurodegenerative disease. J. Am. Geriatr. Soc. 35:1987;334-345.
64. Morgan D.G., Finch C.E. Dopaminergic changes in the basal ganglia. A generalized phenomenon of aging in mammals. Ann. New York Acad. Sci. 515:1988;145-160.
65. Morrison J.H., Hof P.R. Life and death of neurons in the aging brain. Science. 278:1997;412-419.
66. Nagahara A.H., Handa R.J. Age-related changes in c-fos mRNA induction after open-field exposure in the rat brain. Neurobiol. Aging. 18:1997;45-55.
67. Nowak K., Moller H.G., Kuschinsky K. Conditioning of behavioural signs produced by nomifensine and by B-HT 920 in rats. Psychopharmacology. 93:1987;182-187.
68. Osterburg H.H., Donahue H.G., Severson J.A., Finch C.E. Catecholamine levels and turnover during aging in brain regions of male C57BL/6J mice. Brain Res. 224:1981;337-352.
69. Paxinos G., Watson C., Pennisi M., Topple A. Bregma, lambda and the interaural midpoint in stereotaxic surgery with rats of different sex, strain and weight. J. Neurosci. Meth. 13:1985;139-143.
70. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, Academic Press, New York, 1986.
71. Peng Y.I., Lin S.H., Chen T.J., Tai M.Y., Tsai Y.F. Effects of age on open-field behavior of male rats. Chin. J. Physiol. 37:1994;233-236.
72. Pijnenburg A.J., Honig W.M., van der Heyden J.A., van Rossum J.M. Effects of chemical stimulation of the mesolimbic dopamine system upon locomotor activity. Eur. J. Pharmacol. 35:1976;45-58.
73. Plaznik A., Danysz W., Kostowski W. Mesolimbic noradrenaline but not dopamine is responsible for organization of rat behavior in the forced swim test and an anti-immobilizing effect of desipramine. Pol. J. Pharmacol. Pharm. 37:1985;347-357.
74. Ponzio F., Brunello N., Algeri S. Catecholamine synthesis in brain of ageing rat. J. Neurochem. 30:1978;1617-1620.
75. Pradhan S.N. Central neurotransmitters and aging. Life Sci. 26:1980;1643-1656.
76. Richards M., Stern Y., Marder K., Cote L., Mayeux R. Relationships between extrapyramidal signs and cognitive function in a community-dwelling cohort of patients with Parkinson's disease and normal elderly individuals. Ann. Neurol. 33:1993;267-274.
77. Ritz M.C., Lamb R.J., Goldberg S.R., Kuhar M.J. Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science. 237:1987;1219-1223.
78. Rose G.M., Gerhardt G.A., Conboy G.L., Hoffer B.J. Age-related alterations in monoamine release from rat striatum: an in vivo electrochemical study. Neurobiol. Aging. 7:1986;77-82.
79. Sadile A.G., DeLuca B., Cloffi L.A. Long-term habituation to novel environment: amnesic and hypermnesic effects of various post-exposure treatments. Abh. Akad. Wiss. DDR. 5:1979;203-218.
80. Salthouse T.A., Somberg B.L. Isolating the age deficit in speeded performance. J. Gerontol. 37:1982;59-63.
81. Samorajski T., Delaney C., Durham L., Ordy J.M., Johnson J.A., Dunlap W.P. Effect of exercise on longevity, body weight, locomotor performance, and passive-avoidance memory of C57BL/6J mice. Neurobiol. Aging. 6:1985;17-24.
82. Sanberg P.R., Henault M.A., Hagenmeyer-Houser S.H., Russell K.H. The topography of amphetamine and scopolamine-induced hyperactivity: toward an activity print. Behav. Neurosci. 101:1987;131-133.
83. Santiago M., Machado A., Cano J. Effects of age and dopamine agonists and antagonists on striatal dopamine release in the rat: an in vivo microdialysis study. Mech. Ageing Dev. 67:1993;261-267.
84. Shimizu I., Prasad C. Relationship between [3H]mazindol binding to dopamine uptake sites and [3H]dopamine uptake in rat striatum during aging. J. Neurochem. 56:1991;575-579.
85. Soffie M., Buhot M.C., Poucet B. Cognitive and noncognitive processes involved in selective object exploration: comparison between young adult and old rats. Physiol. Behav. 52:1992;1029-1035.
86. Springer J.E., Mu X., Bergmann L.W., Trojanowski J.Q. Expression of GDNF mRNA in rat and human nervous tissue. Exp. Neurol. 127:1994;167-170.
87. van Horne C., Hoffer B.J., Stromberg I., Gerhardt G.A. Clearance and diffusion of locally applied dopamine in normal and 6-hydroxydopamine-lesioned rat striatum. J. Pharmacol. Exp. Ther. 263:1992;1285-1292.
88. Wallace J.E., Krauter E.E., Campbell B.A. Motor and reflexive behavior in the aging rat. J. Gerontol. 35:1980;364-370.
89. Willig F., Palacios A., Monmaur P., M'Harzi M., Laurent J., Delacour J. Short-term memory, exploration and locomotor activity in aged rats. Neurobiol. Aging. 8:1987;393-402.
90. Zee P.C., Rosenberg R.S., Turek F.W. Effects of aging on entrainment and rate of resynchronization of circadian locomotor activity. Am. J. Physiol. 263(2):1992;R1099-R1103.
91. Zelnik N., Angel I., Paul S.M., Kleinman J.E. Decreased density of human striatal dopamine uptake sites with age. Eur. J. Pharmacol. 126:1986;175-176.