Lack of association between dopamine transporter gene polymorphisms and delusional disorder

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 81, Issue 2, 1998, Pages 163-165

  Persico, Antonio M ^a,b   Catalano, Marco ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b UNIVERSITY CAMPUS BIO MEDICO   (Italy)

Author keywords

Delusional disorder; Dopamine; Dopamine transporter; Paranoia; Paraphrenia

Indexed keywords

ADULT; AGED; ALLELE; ARTICLE; DELUSION; DOPAMINE BRAIN LEVEL; DOPAMINE UPTAKE; FEMALE; GENETIC LINKAGE; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ADULT; AGED; ALLELES; CARRIER PROTEINS; CASE-CONTROL STUDIES; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; GENOTYPE; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MIDDLE AGED; MINISATELLITE REPEATS; NERVE TISSUE PROTEINS; POLYMORPHISM, GENETIC; SCHIZOPHRENIA, PARANOID;

EID: 0032574460     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19980328)81:2<163::AID-AJMG7>3.0.CO;2-X     Document Type: Article

References (24)

1. American Psychiatric Association (1987): Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised. American Psychiatric Association, Washington D.C.
2. Endicott J, Spitzer RL (1978): A diagnostic interview: the schedule for affective disorders and schizophrenia. Arch Gen Psychiatry 35:837-844.
3. Funding T (1961): Genetics of paranoid psychoses in later life. Acta Psychiatr Scand 37:267-282.
4. Gawin FH, Kleber HD (1986): Abstinence symptomatology and psychiatric diagnosis in cocaine abusers. Arch Gen Psychiatry 43:107-113.
5. Gelernter J, Kranzler HR, Satel SL, Rao PA (1994): Genetic association between dopamine transporter protein alleles and cocaine-induced paranoia. Neuropsychopharmacol 11:195-199.
6. Gershon ES, Martinez M, Goldin L, Gelernter J, Silver J (1989): Detection of marker associations with a dominant disease gene in genetically complex and heterogeneous diseases. Am J Hum Genet 45:578-585.
7. Giros B, Jaber M, Jones SR, Wightman R, Caron MG (1996): Hyperloco-motion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379:606-612.
8. Honer WG, Gewirtz G, Turey M (1987): Psychosis and violence in cocaine smokers. Lancet 2:451.
9. Horn AS (1990): Dopamine uptake: a review of progress in the last decade. Prog Neurobiol 34:387-400.
10. Jeste DV, Paulsen JS, Harris MJ (1995): Late-onset schizophrenia and other related psychoses. In Bloom FE, and Kupfer DJ (eds). Psychopharmacology: The Fourth Generation of Progress, Raven Press, New York, pp 1437-1446.
11. Kahn RS, Davis KL (1995): New developments in dopamine and schizophrenia. In Bloom FE, and Kupfer DJ (eds). Psychopharmacology: The Fourth Generation of Progress, Raven Press, New York, pp 1193-1203.
12. Kendler KS, McGuire M, Gruenberg AM, Spellman M, O'Hare A, Walsh D (1993): The Roscommon Family Study - II. The risk of nonschizophrenic nonaffective psychoses in relatives. Arch Gen Psychiatry 50: 645-652.
13. Naguib M, McGuffin P, Levy R, Festenstein H, Alonso A (1987): Genetic markers in late paraphrenia: a study of HLA antigens. Br J Psychiatry 150:124-127.
14. Ott J (1991): Analysis of human genetic linkage, rev. ed. Johns Hopkins University Press, Baltimore, Maryland, pp 182-185.
15. Persico AM, Vandenbergh DJ, Smith SS, Uhl GR (1993): Dopamine transporter gene markers are not associated with polysubstance abuse. Biol Psychiatry 34:265-267.
16. Persico AM, Catalano M, Novelli E, Vandenbergh DJ, UM GR, Smeraldi E (1994): Ricerca di VAPSE nel DNA codificante per il trasportatore della dopamina in pazienti psichiatrici. VIIth Meeting of the Italian Society for Biological Psychiatry, Cagliari, Italy. Abstract n. P3, pg. 131.
17. Persico AM, Bird G, Gabbay FH, Uhl GR (1996): D2 dopamine receptor gene TaqI Al and B1 restriction fragment length polymorphisms: enhanced frequencies in psychostimulant-preferring polysubstance abusers. Biol Psychiatry 40:776-784.
18. Persico AM, Macciardi F (1997): Genotypic association between dopamine transporter gene polymorphisms and schizophrenia. Am J Med Genet (Neuropsychiatr Genet) 74:53-57.
19. Risch N, Merikangas K (1996): The future of genetic studies of complex human disease. Science 273:1516-1517.
20. Ritz MC, Lamb RJ, Goldberg SR, Kuhar MJ (1987): Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science 237:1219-1223.
21. Sano A, Kondoh K, Kakimoto Y, Kondo I (1993): A 40-nucleotide repeat polymorphism in the human dopamine transporter gene. Hum Genet 91:405-406.
22. Vandenbergh DJ, Persico AM, Uhl GR (1992a): A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially dimorphic TaqI RFLPs. Mol Brain Res 15:161-166.
23. Vandenbergh DJ, Persico AM, Hawkins AL, Griffin CA, Li X, Jabs EW, Uhl GR (1992b): Human dopamine transporter gene (DAT1) maps to chromosome 5pl5.3 and displays a VNTR. Genomics 14:1104-1106.
24. Vandenbergh DJ, Bendahhou E, Bird GS, Cook E, Gelernter J, Uhl GR (1995): Human dopamine transporter gene 5′ and 3′ structures and molecular genetics. Soc Neurosci Abstr 21:374.