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Volumn 319, Issue 19, 2013, Pages 3035-3041

GW9508, a free fatty acid receptor agonist, specifically induces cell death in bone resorbing precursor cells through increased oxidative stress from mitochondrial origin

Author keywords

Bone; Cell death; Free fatty acid receptor agonist; Oxidative stress

Indexed keywords

FATTY ACID; G PROTEIN COUPLED RECEPTOR 40; GW 9508; UNCLASSIFIED DRUG;

EID: 84886592253     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2013.08.013     Document Type: Article
Times cited : (18)

References (25)
  • 1
    • 0037838892 scopus 로고    scopus 로고
    • The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids
    • Briscoe C.P., et al. The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. J. Biol. Chem. 2003, 278(13):11303-11311.
    • (2003) J. Biol. Chem. , vol.278 , Issue.13 , pp. 11303-11311
    • Briscoe, C.P.1
  • 2
    • 52249093427 scopus 로고    scopus 로고
    • The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding
    • Kebede M., et al. The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding. Diabetes 2008, 57(9):2432-2437.
    • (2008) Diabetes , vol.57 , Issue.9 , pp. 2432-2437
    • Kebede, M.1
  • 3
    • 33846267745 scopus 로고    scopus 로고
    • Life and death decisions of the pancreatic beta-cell: the role of fatty acids
    • Newsholme P., et al. Life and death decisions of the pancreatic beta-cell: the role of fatty acids. Clin Sci. London 2007, 112(1):27-42.
    • (2007) Clin Sci. London , vol.112 , Issue.1 , pp. 27-42
    • Newsholme, P.1
  • 4
    • 20944433543 scopus 로고    scopus 로고
    • The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse
    • Steneberg P., et al. The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse. Cell Metab. 2005, 1(4):245-258.
    • (2005) Cell Metab. , vol.1 , Issue.4 , pp. 245-258
    • Steneberg, P.1
  • 5
    • 34347389002 scopus 로고    scopus 로고
    • The role of G protein-coupled receptor 40 in lipoapoptosis in mouse beta-cell line NIT-1
    • Zhang Y., et al. The role of G protein-coupled receptor 40 in lipoapoptosis in mouse beta-cell line NIT-1. J. Mol. Endocrinol. 2007, 38(6):651-661.
    • (2007) J. Mol. Endocrinol. , vol.38 , Issue.6 , pp. 651-661
    • Zhang, Y.1
  • 6
    • 84860216280 scopus 로고    scopus 로고
    • 'PUFA-GPR40-CREB signaling' hypothesis for the adult primate neurogenesis
    • Yamashima T. 'PUFA-GPR40-CREB signaling' hypothesis for the adult primate neurogenesis. Prog. Lipid. Res. 2012, 51(3):221-231.
    • (2012) Prog. Lipid. Res. , vol.51 , Issue.3 , pp. 221-231
    • Yamashima, T.1
  • 7
    • 77954134133 scopus 로고    scopus 로고
    • Taste preference for fatty acids is mediated by GPR40 and GPR120
    • Cartoni C., et al. Taste preference for fatty acids is mediated by GPR40 and GPR120. J. Neurosci. 2010, 30(25):8376-8382.
    • (2010) J. Neurosci. , vol.30 , Issue.25 , pp. 8376-8382
    • Cartoni, C.1
  • 8
    • 79952315396 scopus 로고    scopus 로고
    • The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin
    • Liou A.P., et al. The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin. Gastroenterology 2011, 140(3):903-912.
    • (2011) Gastroenterology , vol.140 , Issue.3 , pp. 903-912
    • Liou, A.P.1
  • 9
    • 77956165390 scopus 로고    scopus 로고
    • GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects
    • Oh D.Y., et al. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell 2010, 142(5):687-698.
    • (2010) Cell , vol.142 , Issue.5 , pp. 687-698
    • Oh, D.Y.1
  • 10
    • 54349086815 scopus 로고    scopus 로고
    • Modulation of osteoclastogenesis by fatty acids
    • Cornish J., et al. Modulation of osteoclastogenesis by fatty acids. Endocrinology 2008, 149(11):5688-5695.
    • (2008) Endocrinology , vol.149 , Issue.11 , pp. 5688-5695
    • Cornish, J.1
  • 11
    • 84863609091 scopus 로고    scopus 로고
    • Thiazolidinediones induce osteocyte apoptosis by a G protein-coupled receptor 40-dependent mechanism
    • Mieczkowska A., et al. Thiazolidinediones induce osteocyte apoptosis by a G protein-coupled receptor 40-dependent mechanism. J. Biol. Chem. 2012, 287(28):23517-23526.
    • (2012) J. Biol. Chem. , vol.287 , Issue.28 , pp. 23517-23526
    • Mieczkowska, A.1
  • 13
    • 84874781809 scopus 로고    scopus 로고
    • The free fatty acid receptor g protein-coupled receptor 40 (GPR40) protects from bone loss through inhibition of osteoclast differentiation
    • Wauquier F., et al. The free fatty acid receptor g protein-coupled receptor 40 (GPR40) protects from bone loss through inhibition of osteoclast differentiation. J. Biol. Chem. 2013, 288(9):6542-6551.
    • (2013) J. Biol. Chem. , vol.288 , Issue.9 , pp. 6542-6551
    • Wauquier, F.1
  • 14
    • 78650618692 scopus 로고    scopus 로고
    • G-protein-coupled receptor for short-chain fatty acids suppresses colon cancer
    • Tang Y., et al. G-protein-coupled receptor for short-chain fatty acids suppresses colon cancer. Int. J. Cancer 2011, 128(4):847-856.
    • (2011) Int. J. Cancer , vol.128 , Issue.4 , pp. 847-856
    • Tang, Y.1
  • 15
    • 84863125612 scopus 로고    scopus 로고
    • Inhibition of GPR40 protects MIN6 beta cells from palmitate-induced ER stress and apoptosis
    • Wu J., et al. Inhibition of GPR40 protects MIN6 beta cells from palmitate-induced ER stress and apoptosis. J. Cell Biochem. 2012, 113(4):1152-1158.
    • (2012) J. Cell Biochem. , vol.113 , Issue.4 , pp. 1152-1158
    • Wu, J.1
  • 16
    • 21244503501 scopus 로고    scopus 로고
    • Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1
    • Katsuma S., et al. Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1. J. Biol. Chem. 2005, 280(20):19507-19515.
    • (2005) J. Biol. Chem. , vol.280 , Issue.20 , pp. 19507-19515
    • Katsuma, S.1
  • 17
    • 78751513443 scopus 로고    scopus 로고
    • Peroxisome-generated hydrogen peroxide as important mediator of lipotoxicity in insulin-producing cells
    • Elsner M., Gehrmann W., Lenzen S. Peroxisome-generated hydrogen peroxide as important mediator of lipotoxicity in insulin-producing cells. Diabetes 2011, 60(1):200-208.
    • (2011) Diabetes , vol.60 , Issue.1 , pp. 200-208
    • Elsner, M.1    Gehrmann, W.2    Lenzen, S.3
  • 18
    • 48249125013 scopus 로고    scopus 로고
    • Palmitate-induced beta-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms
    • Meidute Abaraviciene S., et al. Palmitate-induced beta-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms. PLoS One 2008, 3(5):e2182.
    • (2008) PLoS One , vol.3 , Issue.5
    • Meidute Abaraviciene, S.1
  • 19
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Droge W. Free radicals in the physiological control of cell function. Physiol. Rev. 2002, 82(1):47-95.
    • (2002) Physiol. Rev. , vol.82 , Issue.1 , pp. 47-95
    • Droge, W.1
  • 20
    • 84855217118 scopus 로고    scopus 로고
    • Mitochondria sentencing about cellular life and death: a matter of oxidative stress
    • Apostolova N., Blas-Garcia A., Esplugues J.V. Mitochondria sentencing about cellular life and death: a matter of oxidative stress. Curr. Pharm. Des. 2011, 17(36):4047-4060.
    • (2011) Curr. Pharm. Des. , vol.17 , Issue.36 , pp. 4047-4060
    • Apostolova, N.1    Blas-Garcia, A.2    Esplugues, J.V.3
  • 21
    • 79958817476 scopus 로고    scopus 로고
    • Regulation of osteoclast apoptosis by Bcl-2 family protein Bim and Caspase-3
    • Tanaka S., et al. Regulation of osteoclast apoptosis by Bcl-2 family protein Bim and Caspase-3. Adv. Exp. Med. Biol. 2010, 658:111-116.
    • (2010) Adv. Exp. Med. Biol. , vol.658 , pp. 111-116
    • Tanaka, S.1
  • 22
    • 77951251430 scopus 로고    scopus 로고
    • Necroptosis as an alternative form of programmed cell death
    • Christofferson D.E., Yuan J. Necroptosis as an alternative form of programmed cell death. Curr. Opin. Cell Biol. 2010, 22(2):263-268.
    • (2010) Curr. Opin. Cell Biol. , vol.22 , Issue.2 , pp. 263-268
    • Christofferson, D.E.1    Yuan, J.2
  • 23
    • 35748944844 scopus 로고    scopus 로고
    • From death receptor to reactive oxygen species and c-Jun N-terminal protein kinase: the receptor-interacting protein 1 odyssey
    • Temkin V., Karin M. From death receptor to reactive oxygen species and c-Jun N-terminal protein kinase: the receptor-interacting protein 1 odyssey. Immunol. Rev. 2007, 220:8-21.
    • (2007) Immunol. Rev. , vol.220 , pp. 8-21
    • Temkin, V.1    Karin, M.2
  • 24
    • 77953672526 scopus 로고    scopus 로고
    • The role of the kinases RIP1 and RIP3 in TNF-induced necrosis
    • Vandenabeele P., et al. The role of the kinases RIP1 and RIP3 in TNF-induced necrosis. Sci. Signal 2010, 3(115):re4.
    • (2010) Sci. Signal , vol.3 , Issue.115
    • Vandenabeele, P.1
  • 25
    • 33745607930 scopus 로고    scopus 로고
    • Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules
    • Briscoe C.P., et al. Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules. Br. J. Pharmacol. 2006, 148(5):619-628.
    • (2006) Br. J. Pharmacol. , vol.148 , Issue.5 , pp. 619-628
    • Briscoe, C.P.1


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