Regulation of osteoclast apoptosis by bcl-2 family protein bim and caspase-3

Advances in Experimental Medicine and Biology

Volumn 658, Issue , 2010, Pages 111-116

  Tanaka, Sakae ^a   Wakeyama, Hidetoshi ^b   Akiyama, Toru ^b   Takahashi, Katsuhiko ^b   Amano, Hitoshi ^b   Nakayama, Keiichi I ^b   Nakamura, Kozo ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b NONE

Author keywords

Apoptosis; Bim; Caspase 3; Osteoclast

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; BIM PROTEIN; CASPASE 3; CASPASE 7; CASPASE 9; COLONY STIMULATING FACTOR 1; CYTOCHROME C; DOXYCYCLINE; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN BCL 2;

APOPTOSIS; CELL ACTIVATION; CELL CYCLE REGULATION; CELL SURVIVAL; CONFERENCE PAPER; DOWN REGULATION; FIBROBLAST; GENE OVEREXPRESSION; LIFESPAN; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CELL SURVIVAL; DOWN-REGULATION; EMBRYO, MAMMALIAN; FIBROBLASTS; MEMBRANE PROTEINS; MICE; MODELS, BIOLOGICAL; OSTEOCLASTS; PROTO-ONCOGENE PROTEINS;

MUS;

EID: 79958817476     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-1050-9_12     Document Type: Conference Paper

References (22)

1. Akiyama, T., Bouillet, P., Miyazaki, T., Kadono, Y., Chikuda, H., Chung, U. I. et al. (2003). Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim. Embo J 22:6653-6664. (Pubitemid 38009611)
2. Bouillet, P., Metcalf, D., Huang, D. C., Tarlinton, D. M., Kay, T. W., Kontgen, F. et al. (1999). Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 286:1735-1738. (Pubitemid 129515880)
3. Bouillet, P., Purton, J. F., Godfrey, D. I., Zhang, L. C., Coultas, L., Puthalakath, H. et al. (2002). -only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 415:922-926. (Pubitemid 34174755)
4. Gilley, J., Coffer, P. J., & Ham, J. (2003). FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J Cell Biol 162:613-622. (Pubitemid 37022939)
5. Huang, D. C., & Strasser, A. (2000). BH3-Only proteins-essential initiators of apoptotic cell death. Cell 103:839-842.
6. Kerr, J. F., Wyllie, A. H., & Currie, A. R. (1972). Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257.
7. Ley, R., Balmanno, K., Hadfield, K., Weston, C. R., & Cook, S. J. (2003). Activation of the ERK1/2 signalling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein Bim. J Biol Chem 278:18811-18816. (Pubitemid 36799262)
8. Meller, R., Cameron, J. A., Torrey, D. J., Clayton, C. E., Ordonez, A. N., Henshall, D. C. et al. (2006). Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons. J Biol Chem 281:7429-7436. (Pubitemid 43847514)
9. Miura, M., Chen, X. D., Allen, M. R., Bi, Y., Gronthos, S., Seo, B. M. et al. (2004). A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells. J Clin Invest 114:1704-1713. (Pubitemid 40385526)
10. Miyazaki, T., Katagiri, H., Kanegae, Y., Takayanagi, H., Sawada, Y., Yamamoto, A. et al (2000). Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts. J Cell Biol 148:333-342. (Pubitemid 30078245)
11. Morishita, H., Makishima, T., Kaneko, C., Lee, Y. S., Segil, N., Takahashi, K. et al. (2001). Deafness due to degeneration of cochlear neurons in caspase-3-deficient mice. Biochem Biophys Res Commun 284:142-149. (Pubitemid 32924320)
12. O'Connor, L., Strasser, A., O'Reilly, L. A., Hausmann, G., Admas, J. M., Cory, S. et al. (1998). Bim: a novel member of the Bcl-2 family that promotes apoptosis. Embo J 17: 384-395. (Pubitemid 28045479)
13. Opferman, J. T., & Korsmeyer, S. J. (2003). Apoptosis in the development and maintenance of the immune system. Nat Immunol 4:410-415. (Pubitemid 36592430)
14. Putcha, G. V., Moulder, K. L., Golden, J. P., Bouillet, P., Adams, J. A., Strasser, A. et al. (2001). Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron 29:615-628. (Pubitemid 32323936)
15. Siegel, R. M. (2006). Caspases at the crossroads of immune-cell life and death. Nat Rev Immunol 6:308-317.
16. Tanaka, S. (2007). Signaling axis in osteoclast biology and therapeutic targeting in the RANKL/RANK/OPG system. Am J Nephrol 27:466-478. (Pubitemid 47482003)
17. Tanaka, S., Nakamura, I., Inoue, J., Oda, H., & Nakamura, K. (2003). Signal transduction pathways regulating osteoclast differentiation and function. J Bone Miner Metab 21:123-133. (Pubitemid 41184293)
18. Tanaka, S., Nakamura, K., Takahasi, N., & Suda, T. (2005). Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system. Immunol Rev 208:30-49. (Pubitemid 41746383)
19. Wakeyama, H., Akiyama, T., Kadono, Y., Nakamura, M., Oshima, Y., Nakamura, K. et al. (2007a). Posttranslational regulation of Bim by caspase-3. Ann N Y Acad Sci 1116:271-280. (Pubitemid 350274312)
20. Wakeyama, H., Akiyama, T., Takahashi, K., Amano, H., Kadono, Y., Nakamura, M. et al. (2007b). Negative feedback loop in the Bim-caspase-3 axis regulating apoptosis and activity of osteoclasts. J Bone Miner Res 22:1631-1639. (Pubitemid 351229333)
21. Wiggins, C. M., Band, H., & Cook, S. J. (2007). c-Cbl is not required for ERK1/2-dependent degradation of BimEL. Cell Signal 19:2605-2611. (Pubitemid 47542300)
22. Wyllie, A. H., Kerr, J. F., & Currie, A. R. (1980). Cell death: the significance of apoptosis. Int Rev Cytol 68:251-306. (Pubitemid 11219226)