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Volumn 76, Issue PART A, 2014, Pages 97-105

Reduced vesicular storage of catecholamines causes progressive degeneration in the locus ceruleus

Author keywords

Locus ceruleus; Norepinephrine; Parkinson's disease; VMAT2

Indexed keywords

DOPAMINE; NISOXETINE; NORADRENALIN; VESICULAR MONOAMINE TRANSPORTER;

EID: 84886587153     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.08.033     Document Type: Article
Times cited : (53)

References (61)
  • 2
    • 0017324287 scopus 로고
    • Norepinephrine-dopamine interactions and behavior
    • S.M. Antelman, and A.R. Caggiula Norepinephrine-dopamine interactions and behavior Science 195 1977 646 653
    • (1977) Science , vol.195 , pp. 646-653
    • Antelman, S.M.1    Caggiula, A.R.2
  • 3
    • 0036392590 scopus 로고    scopus 로고
    • Staging of the intracerebral inclusion body pathology associated with idiopathic Parkinson's disease (preclinical and clinical stages)
    • III/1-5
    • H. Braak Staging of the intracerebral inclusion body pathology associated with idiopathic Parkinson's disease (preclinical and clinical stages) J. Neurol. 249 Suppl. 3 2002 III/1-5
    • (2002) J. Neurol. , vol.249 , Issue.SUPPL. 3
    • Braak, H.1
  • 5
    • 84875278440 scopus 로고    scopus 로고
    • Analysis of vesicular monoamine transporter 2 polymorphisms in Parkinson's disease
    • L. Brighina Analysis of vesicular monoamine transporter 2 polymorphisms in Parkinson's disease Neurobiol. Aging 34 6 2013 1712.e9 1712.e13
    • (2013) Neurobiol. Aging , vol.34 , Issue.6
    • Brighina, L.1
  • 6
    • 38149073317 scopus 로고    scopus 로고
    • Aggregation of alpha-synuclein by DOPAL, the monoamine oxidase metabolite of dopamine
    • W.J. Burke Aggregation of alpha-synuclein by DOPAL, the monoamine oxidase metabolite of dopamine Acta Neuropathol. 115 2008 193 203
    • (2008) Acta Neuropathol. , vol.115 , pp. 193-203
    • Burke, W.J.1
  • 8
    • 44649122740 scopus 로고    scopus 로고
    • Altered vesicular dopamine storage in Parkinson's disease: A premature demise
    • W.M. Caudle Altered vesicular dopamine storage in Parkinson's disease: a premature demise Trends Neurosci. 31 2008 303 308
    • (2008) Trends Neurosci. , vol.31 , pp. 303-308
    • Caudle, W.M.1
  • 9
    • 33745780720 scopus 로고    scopus 로고
    • Polychlorinated biphenyl-induced reduction of dopamine transporter expression as a precursor to Parkinson's disease-associated dopamine toxicity
    • DOI 10.1093/toxsci/kfl018
    • W.M. Caudle Polychlorinated biphenyl-induced reduction of dopamine transporter expression as a precursor to Parkinson's disease-associated dopamine toxicity Toxicol. Sci. 92 2006 490 499 (Pubitemid 44018965)
    • (2006) Toxicological Sciences , vol.92 , Issue.2 , pp. 490-499
    • Caudle, W.M.1    Richardson, J.R.2    Delea, K.C.3    Guillot, T.S.4    Wang, M.5    Pennell, K.D.6    Miller, G.W.7
  • 11
    • 0024436073 scopus 로고
    • Quantitation of catecholamine neurons in the locus coeruleus in human brains of normal young and older adults and in depression
    • V. Chan-Palay, and E. Asan Quantitation of catecholamine neurons in the locus coeruleus in human brains of normal young and older adults and in depression J. Comp. Neurol. 287 1989 357 372 (Pubitemid 19239068)
    • (1989) Journal of Comparative Neurology , vol.287 , Issue.3 , pp. 357-372
    • Chan-Palay, V.1    Asan, E.2
  • 12
    • 33750911761 scopus 로고    scopus 로고
    • Age-related decline in striatal dopamine content and motor performance occurs in the absence of nigral cell loss in a genetic mouse model of Parkinson's disease
    • DOI 10.1111/j.1460-9568.2006.05143.x
    • R.E. Colebrooke Age-related decline in striatal dopamine content and motor performance occurs in the absence of nigral cell loss in a genetic mouse model of Parkinson's disease Eur. J. Neurosci. 24 2006 2622 2630 (Pubitemid 44726774)
    • (2006) European Journal of Neuroscience , vol.24 , Issue.9 , pp. 2622-2630
    • Colebrooke, R.E.1    Humby, T.2    Lynch, P.J.3    McGowan, D.P.4    Xia, J.5    Emson, P.C.6
  • 13
    • 0035834360 scopus 로고    scopus 로고
    • Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct
    • K.A. Conway Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct Science 294 2001 1346
    • (2001) Science , vol.294 , pp. 1346
    • Conway, K.A.1
  • 14
    • 0032051813 scopus 로고    scopus 로고
    • Diorthosubstituted polychlorinated biphenyls in caudate nucleus in Parkinson's disease
    • DOI 10.1006/exnr.1998.6776
    • F.M. Corrigan Diorthosubstituted polychlorinated biphenyls in caudate nucleus in Parkinson's disease Exp. Neurol. 150 1998 339 342 (Pubitemid 28231967)
    • (1998) Experimental Neurology , vol.150 , Issue.2 , pp. 339-342
    • Corrigan, F.M.1    Murray, L.2    Wyatt, C.L.3    Shore, R.F.4
  • 15
    • 51449119082 scopus 로고    scopus 로고
    • Deglycosylation and subcellular redistribution of VMAT2 in the mesostriatal system during normal aging
    • I. Cruz-Muros Deglycosylation and subcellular redistribution of VMAT2 in the mesostriatal system during normal aging Neurobiol. Aging 29 2008 1702 1711
    • (2008) Neurobiol. Aging , vol.29 , pp. 1702-1711
    • Cruz-Muros, I.1
  • 16
    • 0028329215 scopus 로고
    • Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress
    • J. Cubells Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress J. Neurosci. 14 1994 2260 2271 (Pubitemid 24108131)
    • (1994) Journal of Neuroscience , vol.14 , Issue.4 , pp. 2260-2271
    • Cubells, J.F.1    Rayport, S.2    Rajendran, G.3    Sulzer, D.4
  • 17
    • 0028401717 scopus 로고
    • Imaging of myocardial sympathetic innervation with metaiodobenzylguanidine
    • M. Dae Imaging of myocardial sympathetic innervation with metaiodobenzylguanidine J. Nucl. Cardiol. 1 1994 S23 S30
    • (1994) J. Nucl. Cardiol. , vol.1
    • Dae, M.1
  • 18
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: Mechanisms and models
    • DOI 10.1016/S0896-6273(03)00568-3
    • W. Dauer, and S. Przedborski Parkinson's disease: mechanisms and models Neuron 39 2003 889 909 (Pubitemid 37130207)
    • (2003) Neuron , vol.39 , Issue.6 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 19
    • 84878761244 scopus 로고    scopus 로고
    • Dysfunction of the locus coeruleus-norepinephrine system and related circuitry in Parkinson's disease-related dementia
    • K. Del Tredici, and H. Braak Dysfunction of the locus coeruleus-norepinephrine system and related circuitry in Parkinson's disease-related dementia J. Neurol. Neurosurg. Psychiatr. 84 7 2012 774 783
    • (2012) J. Neurol. Neurosurg. Psychiatr. , vol.84 , Issue.7 , pp. 774-783
    • Del Tredici, K.1    Braak, H.2
  • 21
    • 0026712160 scopus 로고
    • Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: Sparing of calbindin-D25k - Containing cells
    • D.C. German Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D25k - containing cells Ann. N. Y. Acad. Sci. 648 1992 42 62
    • (1992) Ann. N. Y. Acad. Sci. , vol.648 , pp. 42-62
    • German, D.C.1
  • 23
    • 31144476794 scopus 로고    scopus 로고
    • Gain-of-function haplotypes in the vesicular monoamine transporter promoter are protective for Parkinson disease in women
    • DOI 10.1093/hmg/ddi445
    • C.E. Glatt Gain-of-function haplotypes in the vesicular monoamine transporter promoter are protective for Parkinson disease in women Hum. Mol. Genet. 15 2006 299 305 (Pubitemid 43125983)
    • (2006) Human Molecular Genetics , vol.15 , Issue.2 , pp. 299-305
    • Glatt, C.E.1    Wahner, A.D.2    White, D.J.3    Ruiz-Linares, A.4    Ritz, B.5
  • 24
    • 0142219814 scopus 로고    scopus 로고
    • Dysautonomia in Parkinson's disease: Neurocardiological abnormalities
    • DOI 10.1016/S1474-4422(03)00555-6
    • D.S. Goldstein Dysautonomia in Parkinson's disease: neurocardiological abnormalities Lancet Neurol. 2 2003 669 676 (Pubitemid 37311320)
    • (2003) Lancet Neurology , vol.2 , Issue.11 , pp. 669-676
    • Goldstein, D.S.1
  • 25
    • 79960983489 scopus 로고    scopus 로고
    • Intra-neuronal vesicular uptake of catecholamines is decreased in patients with Lewy body diseases
    • D.S. Goldstein Intra-neuronal vesicular uptake of catecholamines is decreased in patients with Lewy body diseases J. Clin. Invest. 121 2011 3320 3330
    • (2011) J. Clin. Invest. , vol.121 , pp. 3320-3330
    • Goldstein, D.S.1
  • 27
    • 79954619579 scopus 로고    scopus 로고
    • Catechols in post-mortem brain of patients with Parkinson disease
    • D.S. Goldstein Catechols in post-mortem brain of patients with Parkinson disease Eur. J. Neurol. 18 2011 703 710
    • (2011) Eur. J. Neurol. , vol.18 , pp. 703-710
    • Goldstein, D.S.1
  • 28
    • 84883195985 scopus 로고    scopus 로고
    • Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson disease
    • D.S. Goldstein Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson disease J. Neurochem. 126 5 2013 591 603
    • (2013) J. Neurochem. , vol.126 , Issue.5 , pp. 591-603
    • Goldstein, D.S.1
  • 29
    • 49549112268 scopus 로고    scopus 로고
    • Reduced vesicular storage of dopamine exacerbates methamphetamine-induced neurodegeneration and astrogliosis
    • T.S. Guillot Reduced vesicular storage of dopamine exacerbates methamphetamine-induced neurodegeneration and astrogliosis J. Neurochem. 106 2008 2205 2217
    • (2008) J. Neurochem. , vol.106 , pp. 2205-2217
    • Guillot, T.S.1
  • 31
    • 84867232219 scopus 로고    scopus 로고
    • Association between polychlorinated biphenyls and Parkinson's disease neuropathology
    • J.M. Hatcher-Martin Association between polychlorinated biphenyls and Parkinson's disease neuropathology NeuroToxicology 33 2012 1298 1304
    • (2012) NeuroToxicology , vol.33 , pp. 1298-1304
    • Hatcher-Martin, J.M.1
  • 32
    • 0028258283 scopus 로고
    • Improved assay for plasma dihydroxyphenylacetic acid and other catechols using high-performance liquid chromatography with electrochemical detection
    • DOI 10.1016/0378-4347(93)E0430-X
    • C. Holmes Improved assay for plasma dihydroxyphenylacetic acid and other catechols using high-performance liquid chromatography with electrochemical detection J. Chromatogr. B Biomed. Sci. Appl. 653 1994 131 138 (Pubitemid 24085051)
    • (1994) Journal of Chromatography B: Biomedical Applications , vol.653 , Issue.2 , pp. 131-138
    • Holmes, C.1    Eisenhofer, G.2    Goldstein, D.S.3
  • 33
    • 0021077736 scopus 로고
    • The locus coeruleus and its possible role in ageing and degenerative disease of the human central nervous system
    • DOI 10.1016/0047-6374(83)90100-8
    • D.M. Mann The locus coeruleus and its possible role in ageing and degenerative disease of the human central nervous system Mech. Ageing Dev. 23 1983 73 94 (Pubitemid 14240536)
    • (1983) Mechanisms of Ageing and Development , vol.23 , Issue.1 , pp. 73-94
    • Mann, D.M.A.1
  • 38
    • 65249180086 scopus 로고    scopus 로고
    • Interplay between cytosolic dopamine, calcium, and α-synuclein causes selective death of substantia nigra neurons
    • E.V. Mosharov Interplay between cytosolic dopamine, calcium, and α-synuclein causes selective death of substantia nigra neurons Neuron 62 2009 218 229
    • (2009) Neuron , vol.62 , pp. 218-229
    • Mosharov, E.V.1
  • 40
    • 0026076047 scopus 로고
    • The neuropathologic basis of different clinical subgroups of Parkinsons-disease
    • W. Paulus, and K. Jellinger The neuropathologic basis of different clinical subgroups of Parkinsons-disease J. Neuropathol. Exp. Neurol. 50 1991 743 755.
    • (1991) J. Neuropathol. Exp. Neurol. , vol.50 , pp. 743-755
    • Paulus, W.1    Jellinger, K.2
  • 43
    • 34250025128 scopus 로고    scopus 로고
    • Norepinephrine: The redheaded stepchild of Parkinson's disease
    • DOI 10.1016/j.bcp.2007.01.036, PII S000629520700086X
    • K.S. Rommelfanger, and D. Weinshenker Norepinephrine: the redheaded stepchild of Parkinson's disease Biochem. Pharmacol. 74 2007 177 190 (Pubitemid 46890808)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.2 , pp. 177-190
    • Rommelfanger, K.S.1    Weinshenker, D.2
  • 44
    • 80855139395 scopus 로고    scopus 로고
    • Mitochondrial pathology in Parkinson's disease
    • A.H. Schapira Mitochondrial pathology in Parkinson's disease Mt. Sinai J. Med. 78 2011 872 881
    • (2011) Mt. Sinai J. Med. , vol.78 , pp. 872-881
    • Schapira, A.H.1
  • 45
    • 84860318488 scopus 로고    scopus 로고
    • CNS dopamine transmission mediated by noradrenergic innervation
    • C.C. Smith, and R.W. Greene CNS dopamine transmission mediated by noradrenergic innervation J. Neurosci. 32 2012 6072 6080
    • (2012) J. Neurosci. , vol.32 , pp. 6072-6080
    • Smith, C.C.1    Greene, R.W.2
  • 46
    • 0035789203 scopus 로고    scopus 로고
    • Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice
    • C.G. Specht, and R. Schoepfer Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice BMC Neurosci. 2 2001 11
    • (2001) BMC Neurosci. , vol.2 , pp. 11
    • Specht, C.G.1    Schoepfer, R.2
  • 47
    • 0035664746 scopus 로고    scopus 로고
    • α-synuclein and cytosolic dopamine: Stabilizing a bad situation
    • DOI 10.1038/nm1201-1280
    • D. Sulzer [alpha]-synuclein and cytosolic dopamine: stabilizing a bad situation Nat. Med. 7 2001 1280 1282 (Pubitemid 34007922)
    • (2001) Nature Medicine , vol.7 , Issue.12 , pp. 1280-1282
    • Sulzer, D.1
  • 48
    • 84879601218 scopus 로고    scopus 로고
    • Neuronal vulnerability, pathogenesis, and Parkinson's disease
    • D. Sulzer, and D.J. Surmeier Neuronal vulnerability, pathogenesis, and Parkinson's disease Move. Disord. 28 6 2012 715 724
    • (2012) Move. Disord. , vol.28 , Issue.6 , pp. 715-724
    • Sulzer, D.1    Surmeier, D.J.2
  • 49
    • 0001672745 scopus 로고    scopus 로고
    • Intraneuronal dopamine-quinone synthesis: A review
    • D. Sulzer, and L. Zecca Intraneuronal dopamine-quinone synthesis: a review Neurotoxicity Res. 1 1999 181 195
    • (1999) Neurotoxicity Res. , vol.1 , pp. 181-195
    • Sulzer, D.1    Zecca, L.2
  • 50
    • 65249182524 scopus 로고    scopus 로고
    • A lethal convergence of dopamine and calcium
    • D.J. Surmeier A lethal convergence of dopamine and calcium Neuron 62 2009 163 164
    • (2009) Neuron , vol.62 , pp. 163-164
    • Surmeier, D.J.1
  • 51
    • 20444411546 scopus 로고    scopus 로고
    • Autonomous pacemakers in the basal ganglia: Who needs excitatory synapses anyway?
    • DOI 10.1016/j.conb.2005.05.007, PII S0959438805000723
    • D.J. Surmeier Autonomous pacemakers in the basal ganglia: who needs excitatory synapses anyway? Curr. Opin. Neurobiol. 15 2005 312 318 (Pubitemid 40806443)
    • (2005) Current Opinion in Neurobiology , vol.15 , pp. 312-318
    • Surmeier, D.J.1    Mercer, J.N.2    Chan, C.S.3
  • 52
    • 0030931721 scopus 로고    scopus 로고
    • VMAT2 knockout mice: Heterozygotes display reduced amphetamine- conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity
    • N. Takahashi VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity Proc. Natl. Acad. Sci. 94 1997 9938 9943
    • (1997) Proc. Natl. Acad. Sci. , vol.94 , pp. 9938-9943
    • Takahashi, N.1
  • 53
    • 79955067247 scopus 로고    scopus 로고
    • VMAT2-deficient mice display nigral and extranigral pathology and motor and nonmotor symptoms of Parkinson's disease
    • T.N. Taylor VMAT2-deficient mice display nigral and extranigral pathology and motor and nonmotor symptoms of Parkinson's disease Parkinsons Dis. 2011 2011 124165
    • (2011) Parkinsons Dis. , vol.2011 , pp. 124165
    • Taylor, T.N.1
  • 54
    • 67649379066 scopus 로고    scopus 로고
    • Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity
    • T.N. Taylor Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity J. Neurosci. 29 2009 8103 8113
    • (2009) J. Neurosci. , vol.29 , pp. 8103-8113
    • Taylor, T.N.1
  • 55
    • 0026610297 scopus 로고
    • [3H]nisoxetine: A radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding
    • S.M. Tejani-Butt [3H]nisoxetine: a radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding J. Pharmacol. Exp. Ther. 260 1992 427 436
    • (1992) J. Pharmacol. Exp. Ther. , vol.260 , pp. 427-436
    • Tejani-Butt, S.M.1
  • 56
    • 0033664390 scopus 로고    scopus 로고
    • The VMAT2 gene in mice and humans: Amphetamine responses, locomotion, cardiac arrhythmias, aging, and vulnerability to dopaminergic toxins
    • G.R. Uhl The VMAT2 gene in mice and humans: amphetamine responses, locomotion, cardiac arrhythmias, aging, and vulnerability to dopaminergic toxins FASEB J. 14 2000 2459 2465
    • (2000) FASEB J. , vol.14 , pp. 2459-2465
    • Uhl, G.R.1
  • 57
    • 84862303338 scopus 로고    scopus 로고
    • Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons
    • A. Ulusoy Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons Neurobiol. Dis. 47 2012 367 377
    • (2012) Neurobiol. Dis. , vol.47 , pp. 367-377
    • Ulusoy, A.1
  • 58
    • 80054110342 scopus 로고    scopus 로고
    • Prevalence of orthostatic hypotension in Parkinson's disease: A systematic review and meta-analysis
    • D.C. Velseboer Prevalence of orthostatic hypotension in Parkinson's disease: a systematic review and meta-analysis Parkinsonism Relat. Disord. 17 2011 724 729
    • (2011) Parkinsonism Relat. Disord. , vol.17 , pp. 724-729
    • Velseboer, D.C.1
  • 59
    • 0031458923 scopus 로고    scopus 로고
    • Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine
    • Y.M. Wang Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine Neuron 19 1997 1285 1296
    • (1997) Neuron , vol.19 , pp. 1285-1296
    • Wang, Y.M.1
  • 60
    • 0026339976 scopus 로고
    • Unbiased stereological estimation of the total number of neurons in thesubdivisions of the rat hippocampus using the optical fractionator
    • M.J. West Unbiased stereological estimation of the total number of neurons in thesubdivisions of the rat hippocampus using the optical fractionator Anat. Rec. 231 1991 482 497
    • (1991) Anat. Rec. , vol.231 , pp. 482-497
    • West, M.J.1
  • 61
    • 0037337815 scopus 로고    scopus 로고
    • Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases
    • DOI 10.1001/archneur.60.3.337
    • C. Zarow Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases Arch. Neurol. 60 2003 337 341 (Pubitemid 36314358)
    • (2003) Archives of Neurology , vol.60 , Issue.3 , pp. 337-341
    • Zarow, C.1    Lyness, S.A.2    Mortimer, J.A.3    Chui, H.C.4


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