Genotoxicity profile of Azidothymidine in vitro

Toxicological Sciences

Volumn 135, Issue 2, 2013, Pages 317-327

  Zeller, Andreas ^a   Koenig, Julie ^b   Schmitt, Georg ^a   Singer, Thomas ^a   Guérard, Melanie ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

3 azido 3 deoxythymidine; Ames test; Azidothymidine; Comet assay; L5178Y cells; Micronucleus test; Zidovudine

Indexed keywords

DNA; THYMIDINE; ZIDOVUDINE;

AMES TEST; ANEUGENICITY; ANIMAL CELL; ARTICLE; BACTERIAL STRAIN; CLASTOGENICITY; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA REPAIR; DNA REPLICATION; GENE MUTATION; GENOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; LIVER HOMOGENATE; MAMMAL CELL; MICRONUCLEUS TEST; MOUSE; MUTAGEN TESTING; MUTAGENICITY; NONHUMAN; PHOSPHORYLATION; RAT; SINGLE STRANDED DNA BREAK;

3′-AZIDO-3′-DEOXYTHYMIDINE; AMES TEST; AZIDOTHYMIDINE; COMET ASSAY; L5178Y CELLS; MICRONUCLEUS TEST; ZIDOVUDINE.;

ANIMALS; MUTAGENICITY TESTS; MUTAGENS; ZIDOVUDINE;

EID: 84886563180     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft149     Document Type: Article

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