Nature of DNA lesions induced in human hepatoma cells, human colonic cells and human embryonic lung fibroblasts by the antiretroviral drug 3′-azido-3′-deoxythymidine

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 593, Issue 1-2, 2006, Pages 97-107

  Slameňová, Darina ^a   Horváthová, Eva ^a   Bartková, Miriam ^a  

^a CANCER RESEARCH INSTITUTE   (Slovakia)

Author keywords

3 Azido 3 deoxythymidine (AZT); Human cell lines HepG2 and Caco 2; Human diploid lung fibroblasts HEL; pH variations; Rejoining of strand breaks; Repair enzymes Fpg and Endo III; Single cell gel electrophoresis (SCGE)

Indexed keywords

ANTIRETROVIRUS AGENT; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; TRYPAN BLUE; ZIDOVUDINE;

ARTICLE; CELL STRAIN CACO 2; CELL VIABILITY; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; DNA STRAND; FETUS LUNG; FIBROBLAST; GENOTOXICITY; HEPATOMA CELL; HUMAN; HUMAN CELL; PH; PRIORITY JOURNAL;

CARCINOMA, HEPATOCELLULAR; CELLS, CULTURED; COLON; COMET ASSAY; DNA; DNA DAMAGE; FIBROBLASTS; HUMANS; LUNG; ZIDOVUDINE;

EID: 30944462390     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2005.06.029     Document Type: Article

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