Liquid Chromatography Mass Spectrometry Bioanalysis of Protein Therapeutics and Biomarkers in Biological Matrices

Mass Spectrometry in Drug Metabolism and Disposition: Basic Principles and Applications

Volumn , Issue , 2011, Pages 613-644

  Li, Fumin ^a   Ji, Qin C ^b  

^a 206 Carnegie Center   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

Electrospray ionization (ESI), widely used ionization technique for quantitative LC MS MS analysis of proteins or peptides; Liquid chromatography mass spectrometry bioanalysis of protein therapeutics and biomarkers in biological matrices LC MS MS, analytical platform for protein bioanalysis in applications; Protein quantitation using representative peptides by LC MS MS strategy, hypothesis that proteolytically generated representative peptides, represent intact proteins for quantitation

Indexed keywords

EID: 84886502883     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470929278.ch19     Document Type: Chapter

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