Complexity generation in fungal polyketide biosynthesis: A spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin

ACS Chemical Biology

Volumn 8, Issue 10, 2013, Pages 2322-2330

  Cacho, Ralph A ^a   Chooi, Yit Heng ^a   Zhou, Hui ^a   Tang, Yi ^a,b  

^a University of California   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; GRISEOFULVIN; POLYKETIDE; POLYKETIDE SYNTHASE; BENZOPHENONE; BENZOPHENONE DERIVATIVE; CYTOCHROME P450; MALONYL COENZYME A; ORCINOL; PHLOROGLUCINOL; RESORCINOL DERIVATIVE;

ARTICLE; BIOSYNTHESIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; DERMATOPHYTE; DERMATOPHYTOSIS; ENZYME ACTIVITY; FUNGUS; PENICILLIUM; PENICILLIUM AETHIOPICUM; PRIORITY JOURNAL; TINEA CAPITIS; TINEA PEDIS; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; OXIDATION REDUCTION REACTION; STEREOISOMERISM;

ARTHRODERMATACEAE;

ANTIFUNGAL AGENTS; BENZOPHENONES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; GRISEOFULVIN; MALONYL COENZYME A; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PHLOROGLUCINOL; RESORCINOLS; STEREOISOMERISM;

EID: 84886495241     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400541z     Document Type: Article

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