Linoleic acid attenuates endothelium-derived relaxing factor production by suppressing cAMP-hydrolyzing phosphodiesterase activity

Circulation Journal

Volumn 77, Issue 11, 2013, Pages 2823-2830

  Wei, Jiazhang ^a   Takeuchi, Kazuhiko ^a   Watanabe, Hiroshi ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cyclic AMP; Endothelial cells; Endothelium derived relaxing factor; Linoleic acid; Phosphdiesterase

Indexed keywords

9 (TETRAHYDRO 2 FURYL) ADENINE; CALCIUM ION; CYCLIC AMP; ENDOTHELIUM DERIVED RELAXING FACTOR; FATTY ACID; LINOLEIC ACID; NITRIC OXIDE; PHOSPHODIESTERASE; PROSTACYCLIN; ROLIPRAM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; FLUOROMETRY; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SWINE;

3',5'-CYCLIC-AMP PHOSPHODIESTERASES; ADENINE; ANIMALS; CALCIUM SIGNALING; CELLS, CULTURED; CHEMOKINE CCL2; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENDOTHELIUM-DEPENDENT RELAXING FACTORS; ENZYME INHIBITORS; EPOPROSTENOL; LINOLEIC ACID; NITRIC OXIDE; SWINE; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84886477796     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-13-0248     Document Type: Article

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