Effects of cytochrome P450 inhibitors on agonist-induced Ca2+ responses and production of NO and PGI2 in vascular endothelial cells

Molecular and Cellular Biochemistry

Volumn 248, Issue 1-2, 2003, Pages 129-134

  Takeuchi, Kazuhiko ^a   Watanabe, Hiroshi ^a   Tran, Quang Kim ^a   Ozeki, Mariko ^a   Uehara, Akihiko ^a   Katoh, Hideki ^a   Satoh, Hiroshi ^a   Terada, Hajime ^a   Ohashi, Kyoichi ^a   Hayashi, Hideharu ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Calcium; Cytochrome P450; Endothelial cells; Endothelium derived hyperpolarizing factor; Nitric oxide; Prostacyclin

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; BRADYKININ; CALCIUM ION; CYCLIC GMP; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; ECONAZOLE; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; ENDOTHELIUM DERIVED RELAXING FACTOR; EPOXYICOSATRIENOIC ACID; FURA 2 ACETOXYMETHYL ESTER; MICONAZOLE; NITRIC OXIDE; PROADIFEN; PROSTACYCLIN; THAPSIGARGIN;

ANIMAL CELL; AORTA; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL CULTURE; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; HYPERPOLARIZATION; HYPOTHESIS; NONHUMAN; SWINE; VASCULAR ENDOTHELIUM; VASODILATATION;

6-KETOPROSTAGLANDIN F1 ALPHA; ANIMALS; ANTIFUNGAL AGENTS; BRADYKININ; CALCIUM; CYCLIC GMP; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ECONAZOLE; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; EPOPROSTENOL; MICONAZOLE; NITRIC OXIDE; PROADIFEN; PROSTAGLANDINS I; SIGNAL TRANSDUCTION; SWINE; THAPSIGARGIN; TIME FACTORS;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 12444315960     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1024136318779     Document Type: Article

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