Atherogenic ω-6 lipids modulate PPAR- EGR-1 crosstalk in vascular cells

PPAR Research

Volumn , Issue , 2011, Pages

  Fei, Jia ^a   Cook, Carla ^a   Gillespie, Miriah ^a   Yu, Bangning ^b   Fullen, Khyra ^a   Santanam, Nalini ^a  

^a MARSHALL UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; 3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; EARLY GROWTH RESPONSE FACTOR 1; ESSENTIAL FATTY ACID; LINOLEIC ACID; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; OXIDIZED LINOLEIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AORTA MEDIA; ARTICLE; CELL ADHESION; DOWN REGULATION; MONOCYTE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN PROTEIN INTERACTION; RAT; REGULATORY MECHANISM; SMOOTH MUSCLE FIBER;

EID: 84855263803     PISSN: 16874757     EISSN: 16874765     Source Type: Journal    
DOI: 10.1155/2011/753917     Document Type: Article

References (79)

1. Khachigian L. M., Early growth response-1 in cardiovascular pathobiology Circulation Research 2006 98 2 186 191
2. Pendurthi U. R., Williams J. T., Rao L. V. M., Inhibition of tissue factor gene activation in cultured endothelial cells by curcumin: suppression of activation of transcription factors Egr-1, AP-1, and NF- B Arteriosclerosis, Thrombosis, and Vascular Biology 1997 17 12 3406 3413 (Pubitemid 28028549)
3. Yao J., Mackman N., Edgington T. S., Fan S. T., Lipopolysaccharide induction of the tumor necrosis factor- promoter in human monocytic cells: regulation by Egr-1, c-Jun, and NF- B transcription factors Journal of Biological Chemistry 1997 272 28 17795 17801 (Pubitemid 27311220)
4. Bao X., Lu C., Frangos J. A., Temporal gradient in shear but not steady shear stress induces PDGF-A and MCP-1 expression in endothelial cells: role of NO, NF B, and egr-1 Arteriosclerosis, Thrombosis, and Vascular Biology 1999 19 4 996 1003 (Pubitemid 29177348)
5. Giri R. K., Selvaraj S. K., Kalra V. K., Amyloid peptide-induced cytokine and chemokine expression in THP-1 monocytes is blocked by small inhibitory RNA duplexes for early growth response-1 messenger RNA Journal of Immunology 2003 170 10 5281 5294 (Pubitemid 36554763)
6. Maekawa T., Takahashi N., Honda T., Yonezawa D., Miyashita H., Okui T., Tabeta K., Yamazaki K., Porphyromonas gingivalis antigens and interleukin-6 stimulate the production of monocyte chemoattractant protein-1 via the upregulation of early growth response-1 transcription in human coronary artery endothelial cells Journal of Vascular Research 2009 47 4 346 354
7. Goetze S., Kintscher U., Kaneshiro K., Meehan W. P., Collins A., Fleck E., Hsueh W. A., Law R. E., TNF induces expression of transcription factors c-fos, Egr-1, and Ets-1 in vascular lesions through extracellular signal-regulated kinases 1/2 Atherosclerosis 2001 159 1 93 101 (Pubitemid 33016626)
8. Duan S. Z., Usher M. G., Mortensen R. M., PPARs: the vasculature, inflammation and hypertension Current Opinion in Nephrology and Hypertension 2009 18 2 128 133
9. Robinson E., Grieve D. J., Significance of peroxisome proliferator-activated receptors in the cardiovascular system in health and disease Pharmacology and Therapeutics 2009 122 3 246 263
10. Marx N., Duez H., Fruchart J. C., Staels B., Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells Circulation Research 2004 94 9 1168 1178 (Pubitemid 38656403)
11. Law R. E., Goetze S., Xi X. P., Jackson S., Kawano Y., Demer L., Fishbein M. C., Meehan W. P., Hsueh W. A., Expression and function of PPAR in rat and human vascular smooth muscle cells Circulation 2000 101 11 1311 1318 (Pubitemid 30158620)
12. de Dios S. T., O'Brien R. C., Little P. J., Clinical thiazolidinediones as PPAR ligands with the potential for the prevention of cardiovascular disease in diabetes Current Diabetes Reviews 2006 2 2 227 239 (Pubitemid 44082942)
13. Israelian-Konaraki Z., Reaven P. D., Peroxisome proliferator-activated receptor-alpha and atherosclerosis: from basic mechanisms to clinical implications Cardiology in Review 2005 13 5 240 246 (Pubitemid 41197252)
14. Fruchart J. C., Peroxisome proliferator-activated receptor-alpha (PPAR ): at the crossroads of obesity, diabetes and cardiovascular disease Atherosclerosis 2009 205 1 1 8
15. Altman R., Motton D. D., Kota R. S., Rutledge J. C., Inhibition of vascular inflammation by dehydroepiandrosterone sulfate in human aortic endothelial cells: roles of PPAR and NF- B Vascular Pharmacology 2008 48 2-3 76 84
16. Babaev V. R., Ishiguro H., Ding L., Yancey P. G., Dove D. E., Kovacs W. J., Semenkovich C. F., Fazio S., Linton M. F., Macrophage expression of peroxisome proliferator-activated receptor- reduces atherosclerosis in low-density lipoprotein receptor-deficient mice Circulation 2007 116 12 1404 1412 (Pubitemid 47417567)
17. Krnke G., Kadl A., Ikonomu E., Blml S., Frnkranz A., Sarembock I. J., Bochkov V. N., Exner M., Binder B. R., Leitinger N., Expression of heme oxygenase-1 in human vascular cells is regulated by peroxisome proliferator-activated receptors Arteriosclerosis, Thrombosis, and Vascular Biology 2007 27 6 1276 1282 (Pubitemid 46809415)
18. Barlic J., Murphy P. M., An oxidized lipid-peroxisome proliferator-activated receptor -chemokine pathway in the regulation of macrophage-vascular smooth muscle cell adhesion Trends in Cardiovascular Medicine 2007 17 8 269 274 (Pubitemid 350087697)
19. Jung Y., Song S., Choi C., Peroxisome proliferator activated receptor agonists suppress TNF -induced ICAM-1 expression by endothelial cells in a manner potentially dependent on inhibition of reactive oxygen species Immunology Letters 2008 117 1 63 69
20. Okada M., Yan S. F., Pinsky D. J., Peroxisome proliferator-activated receptor- (PPAR- ) activation suppresses ischemic induction of Egr-1 and its inflammatory gene targets FASEB Journal 2002 16 14 1861 1868 (Pubitemid 35462604)
21. Ichihara S., Obata K., Yamada Y., Nagata K., Noda A., Ichihara G., Yamada A., Kato T., Izawa H., Murohara T., Yokota M., Attenuation of cardiac dysfunction by a PPAR- agonist is associated with down-regulation of redox-regulated transcription factors Journal of Molecular and Cellular Cardiology 2006 41 2 318 329 (Pubitemid 44080222)
22. Fu M., Zhang J., Lin Y., Zhu X., Ehrengruber M. U., Chen Y. E., Early growth response factor-1 is a critical transcriptional mediator of peroxisome proliferator-activated receptor- 1 gene expression in human aortic smooth muscle cells Journal of Biological Chemistry 2002 277 30 26808 26814 (Pubitemid 34951686)
23. Fu M., Zhang J., Lin Y., Zhu X., Zhao L., Ahmad M., Ehrengruber M. U., Chen Y. E., Early stimulation and late inhibition of peroxisome proliferator-activated receptor (PPAR ) gene expression by transformino growth factor in human aortic smooth muscle cells: role of early growth-response factor-1 (Egr-1), activator protein 1 (AP1) and Smads Biochemical Journal 2003 370 3 1019 1025 (Pubitemid 36399096)
24. Delerive P., Furman C., Teissier E., Fruchart J. C., Duriez P., Staels B., Oxidized phospholipids activate PPAR in a phospholipase A2-dependent manner FEBS Letters 2000 471 1 34 38 (Pubitemid 30173288)
25. Nagy L., Tontonoz P., Alvarez J. G. A., Chen H., Evans R. M., Oxidized LDL regulates macrophage gene expression through ligand activation of PPARα Cell 1998 93 2 229 240 (Pubitemid 28180856)
26. Kliewer S. A., Lenhard J. M., Willson T. M., Patel I., Morris D. C., Lehmann J. M., A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor and promotes adipocyte differentiation Cell 1995 83 5 813 819 (Pubitemid 3006325)
27. Forman B. M., Tontonoz P., Chen J., Brun R. P., Spiegelman B. M., Evans R. M., 15-deoxy-12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARα Cell 1995 83 5 803 812 (Pubitemid 3006324)
28. Huang J. T., Welch J. S., Ricote M., Binder C. J., Willson T. M., Kelly C., Witztum J. L., Funk C. D., Conrad D., Glass C. K., Interleukin-4-dependent production of PPAR- ligands in macrophages by 12/15-lipoxygenase Nature 1999 400 6742 378 382 (Pubitemid 29344205)
29. Itoh T., Fairall L., Amin K., Inaba Y., Szanto A., Balint B. L., Nagy L., Yamamoto K., Schwabe J. W. R., Structural basis for the activation of PPAR by oxidized fatty acids Nature Structural and Molecular Biology 2008 15 9 924 931
30. Nettles K. W., Insights into PPAR from structures with endogenous and covalently bound ligands Nature Structural and Molecular Biology 2008 15 9 893 895
31. Whelan J., The health implications of changing linoleic acid intakes Prostaglandins Leukotrienes and Essential Fatty Acids 2008 79 3-5 165 167
32. Kris-Etherton P. M., Hecker K. D., Binkoski A. E., Polyunsaturated fatty acids and cardiovascular health Nutrition Reviews 2004 62 11 414 426 (Pubitemid 39557670)
33. Berry E. M., Who's afraid of n-6 polyunsaturated fatty acids? Methodological considerations for assessing whether they are harmful Nutrition, Metabolism and Cardiovascular Diseases 2001 11 3 181 188 (Pubitemid 33686563)
34. Staprans I., Rapp J. H., Pan X. M., Hardman D. A., Feingold K. R., Oxidized lipids in the diet accelerate the development of fatty streaks in cholesterol-fed rabbits Arteriosclerosis, Thrombosis, and Vascular Biology 1996 16 4 533 538 (Pubitemid 26107724)
35. Totani N., Burenjargal M., Yawata M., Ojiri Y., Chemical properties and cytotoxicity of thermally oxidized oil Journal of Oleo Science 2008 57 3 153 160
36. Alexander J. C., Chemical and biological properties related to toxicity of heated fats Journal of Toxicology and Environmental Health 1981 7 1 125 138 (Pubitemid 11146039)
37. Byrdwell W. C., Neff W. E., Autoxidation products of normal and genetically modified canola oil varieties determined using liquid chromatography with mass spectrometric detection Journal of Chromatography A 2001 905 1-2 85 102 (Pubitemid 33646376)
38. Wassmann S., Wassmann K., Nickenig G., Modulation of oxidant and antioxidant enzyme expression and function in vascular cells Hypertension 2004 44 4 381 386 (Pubitemid 39281479)
39. Wassmann S., Wassmann K., Nickenig G., Regulation of antioxidant and oxidant enzymes in vascular cells and implications for vascular disease Current Hypertension Reports 2006 8 1 69 78
40. Parthasarathy S., Merchant N. K., Penumetcha M., Santanam N., Oxidation and cardiovascular diseasepotential role of oxidants in inducing antioxidant defense enzymes Journal of Nuclear Cardiology 2001 8 3 379 389
41. Fruebis J., Parthasarathy S., Steinberg D., Evidence for a concerted reaction between lipid hydroperoxides and polypeptides Proceedings of the National Academy of Sciences of the United States of America 1992 89 22 10588 10592
42. Pfaffl M. W., A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Research 2001 29 9 E45
43. Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J., Protein measurement with the Folin phenol reagent The Journal of Biological Chemistry 1951 193 1 265 275
44. Jaworski K., Kinard F., Goldstein D., Holvoet P., Trouet A., Schneider Y. J., Remacle C., S-nitrosothiols do not induce oxidative stress, contrary to other nitric oxide donors, in cultures of vascular endothelial or smooth muscle cells European Journal of Pharmacology 2001 425 1 11 19 (Pubitemid 32728295)
45. Yuan J. S., Reed A., Chen F., Stewart C. N., Statistical analysis of real-time PCR data BMC Bioinformatics 2006 7, article no. 85
46. Hsu M. H., Savas U., Griffin K. J., Johnson E. F., Identification of peroxisome proliferator-responsive human genes by elevated expression of the peroxisome proliferator-activated receptor in HepG2 cells Journal of Biological Chemistry 2001 276 30 27950 27958
47. Heinaniemi M., Uski J. O., Degenhardt T., Carlberg C., Meta-analysis of primary target genes of peroxisome proliferator-activated receptors Genome Biology 2007 8 7, article R147
48. Miller Y. I., Choi S. H., Fang L., Tsimikas S., Lipoprotein modification and macrophage uptake: role of pathologic cholesterol transport in atherogenesis Sub-Cellular Biochemistry 2010 51 229 251
49. Furnkranz A., Schober A., Bochkov V. N., Bashtrykov P., Kronke G., Kadl A., Binder B. R., Weber C., Leitinger N., Oxidized phospholipids trigger atherogenic inflammation in murine arteries Arteriosclerosis, Thrombosis, and Vascular Biology 2005 25 3 633 638 (Pubitemid 40315690)
50. Barlic J., Zhang Y., Murphy P. M., Atherogenic lipids induce adhesion of human coronary artery smooth muscle cells to macrophages by up-regulating chemokine CX3CL1 on smooth muscle cells in a TNF -NF B-dependent manner Journal of Biological Chemistry 2007 282 26 19167 19176 (Pubitemid 47100191)
51. Birukov K. G., Oxidized lipids: the two faces of vascular inflammation Current Atherosclerosis Reports 2006 8 3 223 231 (Pubitemid 43676326)
52. Parthasarathy S., Santanam N., Ramachandran S., Meilhac O., Invited review: potential role of oxidized lipids and lipoproteins in antioxidant defense Free Radical Research 2000 33 3 197 215
53. Niki E., Lipid peroxidation: physiological levels and dual biological effects Free Radical Biology and Medicine 2009 47 5 469 484
54. Doran A. C., Meller N., McNamara C. A., Role of smooth muscle cells in the initiation and early progression of atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology 2008 28 5 812 819 (Pubitemid 351544093)
55. Rosenfeld M. E., Inflammation, lipids, and free radicals: lessons learned from the atherogenic process Seminars in Reproductive Endocrinology 1998 16 4 249 261 (Pubitemid 29201007)
56. Friedrichs B., Toborek M., Hennig B., Heinevetter L., Mller C., Brigelius-Flohé R., 13-HPODE and 13-HODE modulate cytokine-induced expression of endothelial cell adhesion molecules differently BioFactors 1999 9 1 61 72 (Pubitemid 29183192)
57. Parthasarathy S., Santanam N., Ramachandran S., Meilhac O., Potential role of oxidized lipids and lipoproteins in antioxidant defense Free Radical Research 2000 33 3 197 215
58. Meilhac O., Zhou M., Santanara N., Parthasarathy S., Lipid peroxides induce expression of catalase in cultured vascular cells Journal of Lipid Research 2000 41 8 1205 1213 (Pubitemid 30666885)
59. Marantos C., Mukaro V., Ferrante J., Hii C., Ferrante A., Inhibition of the lipopolysaccharide-induced stimulation of the members of the MAPK family in human monocytes/macrophages by 4-hydroxynonenal, a product of oxidized omega-6 fatty acids American Journal of Pathology 2008 173 4 1057 1066
60. Huang A., Li C., Kao R. L., Stone W. L., Lipid hydroperoxides inhibit nitric oxide production in RAW264.7 macrophages Free Radical Biology and Medicine 1999 26 5-6 526 537 (Pubitemid 29146255)
61. Kakisis J. D., Liapis C. D., Sumpio B. E., Effects of cyclic strain on vascular cells Endothelium: Journal of Endothelial Cell Research 2004 11 1 17 28 (Pubitemid 38455852)
62. McCaffrey T. A., Fu C., Du B., Eksinar S., Kent K. C., Harry B., Kreiger K., Rosengart T., Cybulsky M. I., Silverman E. S., Collins T., High-level expression of Egr-1 and Egr-1-inducible genes in mouse and human atherosclerosis Journal of Clinical Investigation 2000 105 5 653 662 (Pubitemid 30146512)
63. Hasan R. N., Schafer A. I., Hemin upregulates Egr-1 expression in vascular smooth muscle cells via reactive oxygen species ERK-1/2-Elk-1 and NF- B Circulation Research 2008 102 1 42 50
64. Wang C. C. L., Sharma G., Draznin B., Early growth response gene-1 expression in vascular smooth muscle cells: effects of insulin and oxidant stress American Journal of Hypertension 2006 19 4 366 372
65. Harja E., Bucciarelli L. G., Lu Y., Stern D. M., Zou Y. S., Schmidt A. M., Yan S. F., Early growth response-1 promotes atherogenesis: mice deficient in early growth response-1 and apolipoprotein E display decreased atherosclerosis and vascular inflammation Circulation Research 2004 94 3 333 339 (Pubitemid 38240724)
66. Hamada N., Miyata M., Eto H., Ikeda Y., Shirasawa T., Akasaki Y., Miyauchi T., Furusho Y., Nagaki A., Aronow B. J., Tei C., Loss of clusterin limits atherosclerosis in apolipoprotein E-deficient mice via reduced expression of Egr-1 and TNF-α Journal of Atherosclerosis and Thrombosis 2010 18 3 209 216
67. Khachigian L. M., Lindner V., Williams A. J., Collins T., Egr-1-induced endothelial gene expression: a common theme in vascular injury Science 1996 271 5254 1427 1431 (Pubitemid 26089480)
68. Silverman E. S., Khachigian L. M., Lindner V., Williams A. J., Collins T., Inducible PDGF A-chain transcription in smooth muscle cells is mediated by Egr-1 displacement of Sp1 and Sp3 American Journal of Physiology 1997 273 3 H1415 H1426
69. Biesiada E., Razandi M., Levin E. R., Egr-1 activates basic fibroblast growth factor transcription. Mechanistic implications for astrocyte proliferation Journal of Biological Chemistry 1996 271 31 18576 18581 (Pubitemid 26322719)
70. Ling S., Dai A., Ma Y. H., Chatterjee K., Ives H. E., Sudhir K., Matrix-dependent gene expression of Egr-1 and PDGF A regulate angiotensin II-induced proliferation in human vascular smooth muscle cells Hypertension 1999 34 5 1141 1146
71. Jin N., Hatton N. D., Harrington M. A., Xia X., Larsen S. H., Rhoades R. A., H(2)O(2)-induced egr-1, fra-1, and c-jun gene expression is mediated by tyrosine kinase in aortic smooth muscle cells Free Radical Biology and Medicine 2000 29 8 736 746
72. Auge N., Santanam N., Mori N., Keshava C., Parthasarathy S., Uptake of 13-hydroperoxylinoleic acid by cultured cells Arteriosclerosis, Thrombosis, and Vascular Biology 1999 19 4 925 931 (Pubitemid 29177339)
73. Blessing E., Preusch M., Kranzhofer R., Kinscherf R., Marx N., Rosenfeld M. E., Isermann B., Weber C. M., Kreuzer J., Grfe J., Katus H. A., Bea F., Anti-atherosclerotic properties of telmisartan in advanced atherosclerotic lesions in apolipoprotein E deficient mice Atherosclerosis 2008 199 2 295 303
74. Chapkin R. S., Young Hong M., Fan Y. Y., Davidson L. A., Sanders L. M., Henderson C. E., Barhoumi R., Burghardt R. C., Turner N. D., Lupton J. R., Dietary n-3 PUFA alter colonocyte mitochondrial membrane composition and function Lipids 2002 37 2 193 199 (Pubitemid 34213986)
75. Dadras S. S., Thorgeirsson S. S., Rao M. S., Reddy J. K., Implication of hydrogen peroxide generation and apoptosis in the neoplastic transformation of mouse fibroblasts overexpressing peroxisomal fatty acyl-CoA oxidase International Journal of Oncology 1998 12 1 37 44 (Pubitemid 28027226)
76. Bochkov V. N., Mechtcheriakova D., Lucerna M., Huber J., Malli R., Graier W. F., Hofer E., Binder B. R., Leitinger N., Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca++/NFAT Blood 2002 99 1 199 206
77. Chiu J. J., Wung B. S., Hsieh H. J., Lo L. W., Wang D. L., Nitric oxide regulates shear stress-induced early growth response-1: expression via the extracellular signal-regulated kinase pathway in endothelial cells Circulation Research 1999 85 3 238 246 (Pubitemid 29377295)
78. Folcik V. A., Nivar-Aristy R. A., Krajewski L. P., Cathcart M. K., Lipoxygenase contributes to the oxidation of lipids in human atherosclerotic plaques Journal of Clinical Investigation 1995 96 1 504 510
79. Uchida K., Lipid peroxidation and redox-sensitive signaling pathways Current Atherosclerosis Reports 2007 9 3 216 221 (Pubitemid 47629069)