Asymmetric synthesis of β-hydroxy-α-amino phosphonic acid derivatives via organocatalytic direct aldol reaction of α-isothiocyanato phosphonates with aldehydes

Journal of Organic Chemistry

Volumn 78, Issue 20, 2013, Pages 10541-10547

  Han, Wen Yong ^a,c   Zhao, Jian Qiang ^a,c   Wu, Zhi Jun ^b   Zhang, Xiao Mei ^a   Yuan, Wei Cheng ^a  

^a CHENGDU INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b CHENGDU INSTITUTE OF BIOLOGY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPHOSPHONATES; ASYMMETRIC SYNTHESIS; DIRECT ALDOL REACTION; ORGANOCATALYTIC; PHOSPHONATES; PHOSPHONIC ACIDS; STEREOCENTERS;

CHEMICAL COMPOUNDS; CONDENSATION REACTIONS; NUCLEOPHILES; ORGANIC ACIDS;

ALDEHYDES;

ALDEHYDE; ALPHA ISOTHIOCYANATO PHOSPHONATE DERIVATIVE; BETA HYDROXY ALPHA AMINO PHOSPHONIC ACID DERIVATIVE; NUCLEOPHILE; PHOSPHONIC ACID DERIVATIVE; QUININE; THIOUREA; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; CYCLIZATION; X RAY CRYSTALLOGRAPHY;

ALDEHYDES; AMINO ACIDS; CATALYSIS; CYCLIZATION; ISOTHIOCYANATES; MOLECULAR STRUCTURE; PHOSPHOROUS ACIDS; THIOUREA;

EID: 84886435243     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo401779x     Document Type: Article

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