Enantioselective construction of quaternary α-carbon centers on α-amino phosphonates via catalytic asymmetric allylation

Organic Letters

Volumn 1, Issue 6, 1999, Pages 837-839

  Kuwano, Ryoichi ^a   Nishio, Ryo ^a   Ito, Yoshihiko ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001687230     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol990679f     Document Type: Article

References (49)

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41. 4, and evaporated under reduced pressure. The residue was purified by preparative TLC (EtOAc/MeOH = 10/1), giving 3.
42. The palladium catalyst prepared in situ from [Pd(π-allyl)Cl]2 was also effective for the asymmetric reaction to give 86% ee of 3a. However, the reaction rate was somewhat slow.
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48. 1H NMR analysis of the O-methylmandelate derivative of syn-6 according to Trost's procedure (see ref 20). Further details are described in the Supporting Information.
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