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Volumn 27, Issue , 2013, Pages 3-13

Use of asenapine in clinical practice for the management of bipolar mania

Author keywords

antimanic efficacy; Asenapine; atypical antipsychotic; bipolar disorder; bipolar mania; depressive symptoms; mixed episode

Indexed keywords

ASENAPINE; FUSED HETEROCYCLIC RINGS; NEUROLEPTIC AGENT;

EID: 84886432739     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/1359786813482534     Document Type: Article
Times cited : (12)

References (67)
  • 1
    • 77956913686 scopus 로고    scopus 로고
    • Duration of untreated illness and suicide in bipolar disorder: A naturalistic study
    • Altamura AC Dell’Osso B Berlin HA. (2010) Duration of untreated illness and suicide in bipolar disorder: A naturalistic study. Eur Arch Psychiatry Clin Neurosci 260: 385–391.
    • (2010) Eur Arch Psychiatry Clin Neurosci , vol.260 , pp. 385-391
    • Altamura, A.C.1    Dell’Osso, B.2    Berlin, H.A.3
  • 2
    • 84870469320 scopus 로고    scopus 로고
    • 4th ed., text revision (DSM-IV-TR). Washington DC: American Psychiatric Press.
    • American Psychiatric Association (2000) Diagnostic and Statistical Manual of Mental Disorders, 4th ed., text revision (DSM-IV-TR). Washington DC: American Psychiatric Press.
    • (2000) Diagnostic and Statistical Manual of Mental Disorders
  • 3
    • 84875632199 scopus 로고    scopus 로고
    • 5th ed. (DSM-5). DSM-5 Development. Available at: (accessed 6 February 2013).
    • American Psychiatric Association (2012) Diagnostic and Statistical Manual of Mental Disorders, 5th ed. (DSM-5). DSM-5 Development. Available at: http://www.dsm5.org/Pages/Default.aspx (accessed 6 February 2013).
    • (2012) Diagnostic and Statistical Manual of Mental Disorders
  • 4
    • 0034666204 scopus 로고    scopus 로고
    • Historical perspectives and natural history of bipolar disorder
    • Angst J Sellaro R (2000) Historical perspectives and natural history of bipolar disorder. Biol Psychiatry 48: 445–457.
    • (2000) Biol Psychiatry , vol.48 , pp. 445-457
    • Angst, J.1    Sellaro, R.2
  • 5
    • 84872861182 scopus 로고    scopus 로고
    • Effect of asenapine on manic and depressive symptoms in bipolar I patients with mixed episodes: Results from post hoc analyses
    • Azorin JM Sapin C Weiller E (2013) Effect of asenapine on manic and depressive symptoms in bipolar I patients with mixed episodes: Results from post hoc analyses. J Affect Disord 145: 62–69.
    • (2013) J Affect Disord , vol.145 , pp. 62-69
    • Azorin, J.M.1    Sapin, C.2    Weiller, E.3
  • 6
    • 84990372171 scopus 로고    scopus 로고
    • Incidence, onset and duration of treatment-emergent somnolence with asenapine in patients with schizophrenia or bipolar disorder
    • Poster presented at the 20th European Congress of Psychiatry, March Prague, Czech Republic.
    • Cazorla P Zhao J Szegedi A (2012a) Incidence, onset and duration of treatment-emergent somnolence with asenapine in patients with schizophrenia or bipolar disorder. Poster presented at the 20th European Congress of Psychiatry, 3–6 March 2012, Prague, Czech Republic.
    • (2012)
    • Cazorla, P.1    Zhao, J.2    Szegedi, A.3
  • 7
    • 84930485789 scopus 로고    scopus 로고
    • Safety and tolerability of switching to asenapine from other antipsychotic agents: Pooled results from two randomized multicenter trials in stable patients with persistent negative symptoms in schizophrenia
    • Cazorla P Mackle M Zhao J (2012b) Safety and tolerability of switching to asenapine from other antipsychotic agents: Pooled results from two randomized multicenter trials in stable patients with persistent negative symptoms in schizophrenia. Neuropsychiatr Dis Treat 8: 247–257.
    • (2012) Neuropsychiatr Dis Treat , vol.8 , pp. 247-257
    • Cazorla, P.1    Mackle, M.2    Zhao, J.3
  • 8
    • 13644267314 scopus 로고    scopus 로고
    • Recovery and functional outcomes following olanzapine treatment for bipolar I mania
    • Chengappa KN Hennen J Baldessarini RJ (2005) Recovery and functional outcomes following olanzapine treatment for bipolar I mania. Bipolar Disord 7: 68–76.
    • (2005) Bipolar Disord , vol.7 , pp. 68-76
    • Chengappa, K.N.1    Hennen, J.2    Baldessarini, R.J.3
  • 9
    • 84866238212 scopus 로고    scopus 로고
    • Prolactin, hyperprolactinaemia and antipsychotic treatment: A review and lessons for treatment of early psychosis
    • Cookson J Hodgson R Wildgust HJ (2012) Prolactin, hyperprolactinaemia and antipsychotic treatment: A review and lessons for treatment of early psychosis. J Psychopharmacol 26: S42–S51.
    • (2012) J Psychopharmacol , vol.26 , pp. S42-S51
    • Cookson, J.1    Hodgson, R.2    Wildgust, H.J.3
  • 10
    • 33744929112 scopus 로고    scopus 로고
    • Mortality among first-admission patients with psychosis
    • Craig TJ Ye Q Bromet EJ (2006) Mortality among first-admission patients with psychosis. Compr Psychiatry 47: 246–251.
    • (2006) Compr Psychiatry , vol.47 , pp. 246-251
    • Craig, T.J.1    Ye, Q.2    Bromet, E.J.3
  • 11
    • 1042291224 scopus 로고    scopus 로고
    • A systematic review evaluating health-related quality of life, work impairment, and healthcare costs and utilization in bipolar disorder
    • Dean BB Gerner D Gerner RH (2004) A systematic review evaluating health-related quality of life, work impairment, and healthcare costs and utilization in bipolar disorder. Curr Med Res Opin 20: 139–154.
    • (2004) Curr Med Res Opin , vol.20 , pp. 139-154
    • Dean, B.B.1    Gerner, D.2    Gerner, R.H.3
  • 12
    • 35348890745 scopus 로고    scopus 로고
    • Atypical antipsychotics in bipolar disorder: Systematic review of randomised trials
    • Derry S Moore RA (2007) Atypical antipsychotics in bipolar disorder: Systematic review of randomised trials. BMC Psychiatry 7: 40.
    • (2007) BMC Psychiatry , vol.7 , pp. 40
    • Derry, S.1    Moore, R.A.2
  • 13
    • 84866362554 scopus 로고    scopus 로고
    • A UK panel consensus on the initiation of aripiprazole for the treatment of bipolar mania
    • Dratcu L Bobmanuel S Davies W (2012) A UK panel consensus on the initiation of aripiprazole for the treatment of bipolar mania. Int J Psychiatry Clin Pract 16: 244–258.
    • (2012) Int J Psychiatry Clin Pract , vol.16 , pp. 244-258
    • Dratcu, L.1    Bobmanuel, S.2    Davies, W.3
  • 15
    • 84990329088 scopus 로고    scopus 로고
    • Committee for Medicinal Products for Human Use (CHMP) assessment report for Sycrest®
    • Available at: (accessed 6 February 2013).
    • European Medicines Agency (2010) Committee for Medicinal Products for Human Use (CHMP) assessment report for Sycrest®. Available at: http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001177/human_med_001379.jsp&mid=WC0b01ac058001d124 (accessed 6 February 2013).
    • (2010)
  • 16
    • 53049088876 scopus 로고    scopus 로고
    • Treatment of bipolar disorder: A systematic review of available data and clinical perspectives
    • Fountoulakis KN Vieta E (2008) Treatment of bipolar disorder: A systematic review of available data and clinical perspectives. Int J Neuropsychopharmacol 11: 999–1029.
    • (2008) Int J Neuropsychopharmacol , vol.11 , pp. 999-1029
    • Fountoulakis, K.N.1    Vieta, E.2
  • 17
    • 34547179023 scopus 로고    scopus 로고
    • Epidemiology, diagnosis and management of mixed mania
    • González-Pinto A Aldama A Mosquera F (2007) Epidemiology, diagnosis and management of mixed mania. CNS Drugs 21: 611–626.
    • (2007) CNS Drugs , vol.21 , pp. 611-626
    • González-Pinto, A.1    Aldama, A.2    Mosquera, F.3
  • 18
    • 79959261961 scopus 로고    scopus 로고
    • Poor long-term prognosis in mixed bipolar patients: 10-year outcomes in the Vitoria prospective naturalistic study in Spain
    • González-Pinto A Barbeito S Alonso M. (2011) Poor long-term prognosis in mixed bipolar patients: 10-year outcomes in the Vitoria prospective naturalistic study in Spain. J Clin Psychiatry 72: 671–676.
    • (2011) J Clin Psychiatry , vol.72 , pp. 671-676
    • González-Pinto, A.1    Barbeito, S.2    Alonso, M.3
  • 19
    • 65649095161 scopus 로고    scopus 로고
    • Evidence-based guidelines for treating bipolar disorder: Revised second edition – recommendations from the British Association for Psychopharmacology
    • Goodwin GM; Consensus Group of the British Association for Psychopharmacology (2009). Evidence-based guidelines for treating bipolar disorder: Revised second edition – recommendations from the British Association for Psychopharmacology. J Psychopharmacol 23: 346–388.
    • (2009) J Psychopharmacol , vol.23 , pp. 346-388
    • Goodwin, G.M.1
  • 20
    • 84876474300 scopus 로고    scopus 로고
    • Occupational disability in bipolar disorder: Analysis of predictors of being on severe disablement benefit (PREBIS study data)
    • DOI: 10.1111/acps.12003.
    • Grande I Goikolea JM de Dios C; for the PREBIS group (2012) Occupational disability in bipolar disorder: Analysis of predictors of being on severe disablement benefit (PREBIS study data). Acta Psychiatr Scand DOI: 10.1111/acps.12003.
    • (2012) Acta Psychiatr Scand
    • Grande, I.1    Goikolea, J.M.2    de Dios, C.3
  • 21
    • 67650134119 scopus 로고    scopus 로고
    • The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: Update 2009 on the treatment of acute mania
    • Grunze H Vieta E Goodwin GM. (2009) The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: Update 2009 on the treatment of acute mania. World J Biol Psychiatry 10: 85–116.
    • (2009) World J Biol Psychiatry , vol.10 , pp. 85-116
    • Grunze, H.1    Vieta, E.2    Goodwin, G.M.3
  • 22
    • 78149357550 scopus 로고    scopus 로고
    • Poor adherence to treatment associated with a high recurrence in a bipolar disorder outpatient sample
    • Gutiérrez-Rojas L Jurado D Martínez-Ortega JM. (2010) Poor adherence to treatment associated with a high recurrence in a bipolar disorder outpatient sample. J Affect Disord 127: 77–83.
    • (2010) J Affect Disord , vol.127 , pp. 77-83
    • Gutiérrez-Rojas, L.1    Jurado, D.2    Martínez-Ortega, J.M.3
  • 23
    • 60849110573 scopus 로고    scopus 로고
    • The effect of antipsychotic medication on sexual function and serum prolactin levels in community-treated schizophrenic patients: Results from the Schizophrenia Trial of Aripiprazole (STAR) study (NCT00237913)
    • Hanssens L L’Italien G Loze JY. (2008) The effect of antipsychotic medication on sexual function and serum prolactin levels in community-treated schizophrenic patients: Results from the Schizophrenia Trial of Aripiprazole (STAR) study (NCT00237913). BMC Psychiatry 8: 95.
    • (2008) BMC Psychiatry , vol.8 , pp. 95
    • Hanssens, L.1    L’Italien, G.2    Loze, J.Y.3
  • 24
    • 79952362059 scopus 로고    scopus 로고
    • 2-year course of bipolar disorder type I patients in outpatient care: Factors associated with remission and functional recovery
    • Haro JM Reed C Gonzalez-Pinto A EMBLEM Advisory Board (2011) 2-year course of bipolar disorder type I patients in outpatient care: Factors associated with remission and functional recovery. Eur Neuropsychopharmacol 21: 287–293.
    • (2011) Eur Neuropsychopharmacol , vol.21 , pp. 287-293
    • Haro, J.M.1    Reed, C.2    Gonzalez-Pinto, A.3
  • 25
    • 51149123494 scopus 로고    scopus 로고
    • Adverse effects of prolactin in rodents and humans: Breast and prostate cancer
    • Harvey PW Everett DJ Springall CJ (2008) Adverse effects of prolactin in rodents and humans: Breast and prostate cancer. J Psychopharmacol 22: S20–S27.
    • (2008) J Psychopharmacol , vol.22 , pp. S20-S27
    • Harvey, P.W.1    Everett, D.J.2    Springall, C.J.3
  • 26
    • 35648948443 scopus 로고    scopus 로고
    • Weight gain with atypical antipsychotics: Evidence and insights
    • Henderson DC (2007) Weight gain with atypical antipsychotics: Evidence and insights. J Clin Psychiatry 68: S18–S26.
    • (2007) J Clin Psychiatry , vol.68 , pp. S18-S26
    • Henderson, D.C.1
  • 27
    • 0036270011 scopus 로고    scopus 로고
    • The long-term natural history of the weekly symptomatic status of bipolar I disorder
    • Judd LL Akiskal HS Schettler PJ. (2002) The long-term natural history of the weekly symptomatic status of bipolar I disorder. Arch Gen Psychiatry 59: 530–537.
    • (2002) Arch Gen Psychiatry , vol.59 , pp. 530-537
    • Judd, L.L.1    Akiskal, H.S.2    Schettler, P.J.3
  • 28
    • 45749147916 scopus 로고    scopus 로고
    • Atypical antipsychotics: Sedation versus efficacy
    • Kane JM Sharif ZA (2008) Atypical antipsychotics: Sedation versus efficacy. J Clin Psychiatry 69: S18–S31.
    • (2008) J Clin Psychiatry , vol.69 , pp. S18-S31
    • Kane, J.M.1    Sharif, Z.A.2
  • 29
    • 37449021988 scopus 로고    scopus 로고
    • Suicidal events and accidents in 216 first-episode bipolar I disorder patients: Predictive factors
    • Khalsa HM Salvatore P Hennen J. (2008) Suicidal events and accidents in 216 first-episode bipolar I disorder patients: Predictive factors. J Affect Disord 106: 179–184.
    • (2008) J Affect Disord , vol.106 , pp. 179-184
    • Khalsa, H.M.1    Salvatore, P.2    Hennen, J.3
  • 31
    • 0036891935 scopus 로고    scopus 로고
    • Metabolic syndrome and development of diabetes mellitus: Application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study
    • Laaksonen DE Lakka HM Niskanen LK. (2002) Metabolic syndrome and development of diabetes mellitus: Application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study. Am J Epidemiol 156: 1070–1077.
    • (2002) Am J Epidemiol , vol.156 , pp. 1070-1077
    • Laaksonen, D.E.1    Lakka, H.M.2    Niskanen, L.K.3
  • 32
    • 0037021505 scopus 로고    scopus 로고
    • The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men
    • Lakka HM Laaksonen DE Lakka TA. (2002) The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 288: 2709–2716.
    • (2002) JAMA , vol.288 , pp. 2709-2716
    • Lakka, H.M.1    Laaksonen, D.E.2    Lakka, T.A.3
  • 33
    • 56749109789 scopus 로고    scopus 로고
    • Impact of bipolar disorder in employed populations
    • Laxman KE Lovibond KS Hassan MK (2008) Impact of bipolar disorder in employed populations. Am J Manag Care 14: 757–764.
    • (2008) Am J Manag Care , vol.14 , pp. 757-764
    • Laxman, K.E.1    Lovibond, K.S.2    Hassan, M.K.3
  • 34
    • 0036217353 scopus 로고    scopus 로고
    • Treatment non-adherence in affective disorders
    • Lingam R Scott J (2002) Treatment non-adherence in affective disorders. Acta Psychiatr Scand 105: 164–172.
    • (2002) Acta Psychiatr Scand , vol.105 , pp. 164-172
    • Lingam, R.1    Scott, J.2
  • 35
    • 78651327657 scopus 로고    scopus 로고
    • Screening and management of bipolar disorders: methodology
    • Llorca PM Courtet P Martin P. (2010a) Screening and management of bipolar disorders: methodology. Encephale 36: S79–S85.
    • (2010) Encephale , vol.36 , pp. S79-S85
    • Llorca, P.M.1    Courtet, P.2    Martin, P.3
  • 36
    • 78651291582 scopus 로고    scopus 로고
    • Screening and management of bipolar disorders: results
    • Llorca PM Courtet P Martin P; l’Association Française de Psychiatrie Biologique et Neuropsychopharmacologique (AFPBN) (2010b) Screening and management of bipolar disorders: results. Encephale 36: S86–S102.
    • (2010) Encephale , vol.36 , pp. S86-S102
    • Llorca, P.M.1    Courtet, P.2    Martin, P.3
  • 37
    • 79955647944 scopus 로고    scopus 로고
    • Long-term treatment of bipolar disorder in adults
    • McIntyre RS (2011) Long-term treatment of bipolar disorder in adults. J Clin Psychiatry 72: e06.
    • (2011) J Clin Psychiatry , vol.72 , pp. e06
    • McIntyre, R.S.1
  • 38
    • 70350540771 scopus 로고    scopus 로고
    • A 3-week, randomized, placebo-controlled trial of asenapine in the treatment of acute mania in bipolar mania and mixed states
    • McIntyre RS Cohen M Zhao J. (2009a) A 3-week, randomized, placebo-controlled trial of asenapine in the treatment of acute mania in bipolar mania and mixed states. Bipolar Disord 11: 673–686.
    • (2009) Bipolar Disord , vol.11 , pp. 673-686
    • McIntyre, R.S.1    Cohen, M.2    Zhao, J.3
  • 39
    • 71049147614 scopus 로고    scopus 로고
    • Asenapine versus olanzapine in acute mania: a double-blind extension study
    • McIntyre RS Cohen M Zhao J (2009b) Asenapine versus olanzapine in acute mania: a double-blind extension study. Bipolar Disord 11: 815–826.
    • (2009) Bipolar Disord , vol.11 , pp. 815-826
    • McIntyre, R.S.1    Cohen, M.2    Zhao, J.3
  • 40
    • 77649340254 scopus 로고    scopus 로고
    • Asenapine in the treatment of acute mania in bipolar I disorder: a randomized, double-blind, placebo-controlled trial
    • McIntyre RS Cohen M Zhao J. (2010a) Asenapine in the treatment of acute mania in bipolar I disorder: a randomized, double-blind, placebo-controlled trial. J Affect Disord 122: 27–38.
    • (2010) J Affect Disord , vol.122 , pp. 27-38
    • McIntyre, R.S.1    Cohen, M.2    Zhao, J.3
  • 41
    • 77957334940 scopus 로고    scopus 로고
    • Asenapine for long-term treatment of bipolar disorder: a double-blind 40-week extension study
    • McIntyre RS Cohen M Zhao J. (2010b) Asenapine for long-term treatment of bipolar disorder: a double-blind 40-week extension study. J Affect Disord 126: 358–365.
    • (2010) J Affect Disord , vol.126 , pp. 358-365
    • McIntyre, R.S.1    Cohen, M.2    Zhao, J.3
  • 42
    • 40749140713 scopus 로고    scopus 로고
    • Prolactin awareness: An essential consideration for physical health in schizophrenia
    • Montejo AL (2008) Prolactin awareness: An essential consideration for physical health in schizophrenia. Eur Neuropsychopharmacol 18: S108–S114.
    • (2008) Eur Neuropsychopharmacol , vol.18 , pp. S108-S114
    • Montejo, A.L.1
  • 43
    • 34249329350 scopus 로고    scopus 로고
    • Bipolar disorder: The management of bipolar disorder in adults, children and adolescents, in primary and secondary care
    • Clinical Guidance 38. Available at: (accessed 6 February 2013).
    • National Institute for Health and Clinical Excellence (NICE) (2006) Clinical Guidance 38. Bipolar disorder: The management of bipolar disorder in adults, children and adolescents, in primary and secondary care. Available at: http://www.nice.org.uk/CG38 (accessed 6 February 2013).
    • (2006)
  • 44
    • 0037799006 scopus 로고    scopus 로고
    • Safety of available agents used to treat bipolar disorder: Focus on weight gain
    • Nemeroff CB (2003) Safety of available agents used to treat bipolar disorder: Focus on weight gain. J Clin Psychiatry 64: 532–539.
    • (2003) J Clin Psychiatry , vol.64 , pp. 532-539
    • Nemeroff, C.B.1
  • 45
    • 33746737583 scopus 로고    scopus 로고
    • The metabolic effects of antipsychotic medications
    • Newcomer JW Haupt DW (2006) The metabolic effects of antipsychotic medications. Can J Psychiatry 51: 480–491.
    • (2006) Can J Psychiatry , vol.51 , pp. 480-491
    • Newcomer, J.W.1    Haupt, D.W.2
  • 46
    • 0028171088 scopus 로고
    • Putting the ‘A’ in atypical: does α2-adrenoceptor antagonism account for the therapeutic advantage of new antipsychotics?
    • Nutt DJ (1994) Putting the ‘A’ in atypical: does α2-adrenoceptor antagonism account for the therapeutic advantage of new antipsychotics? J Psychopharmacol 8: 193–195.
    • (1994) J Psychopharmacol , vol.8 , pp. 193-195
    • Nutt, D.J.1
  • 47
    • 51149097397 scopus 로고    scopus 로고
    • Antipsychotic-induced hyperprolactinaemia, hypogonadism and osteoporosis in the treatment of schizophrenia
    • O’Keane V (2008) Antipsychotic-induced hyperprolactinaemia, hypogonadism and osteoporosis in the treatment of schizophrenia. J Psychopharmacol 22: S70–S75.
    • (2008) J Psychopharmacol , vol.22 , pp. S70-S75
    • O’Keane, V.1
  • 48
    • 0024421678 scopus 로고
    • Idazoxan: A selective alpha 2-antagonist and effective sustained antidepressant in two bipolar depressed patients
    • Osman OT Rudorfer MV Potter WZ (1989) Idazoxan: A selective alpha 2-antagonist and effective sustained antidepressant in two bipolar depressed patients. Arch Gen Psychiatry 46: 958–959.
    • (1989) Arch Gen Psychiatry , vol.46 , pp. 958-959
    • Osman, O.T.1    Rudorfer, M.V.2    Potter, W.Z.3
  • 49
    • 0033573710 scopus 로고    scopus 로고
    • Randomised controlled trial of efficacy of teaching patients with bipolar disorder to identify early symptoms of relapse and obtain treatment
    • Perry A Tarrier N Morriss R (1999) Randomised controlled trial of efficacy of teaching patients with bipolar disorder to identify early symptoms of relapse and obtain treatment. BMJ 318: 149–153.
    • (1999) BMJ , vol.318 , pp. 149-153
    • Perry, A.1    Tarrier, N.2    Morriss, R.3
  • 50
    • 1542376192 scopus 로고    scopus 로고
    • Enhancement of treatment adherence among patients with bipolar disorder
    • Sajatovic M Davies M Hrouda DR (2004) Enhancement of treatment adherence among patients with bipolar disorder. Psychiatr Serv 55: 264–269.
    • (2004) Psychiatr Serv , vol.55 , pp. 264-269
    • Sajatovic, M.1    Davies, M.2    Hrouda, D.R.3
  • 52
    • 84990315626 scopus 로고    scopus 로고
    • Available at US Food & Drug Administration website: (accessed 6 February 2013).
    • Saphris® Prescribing Information (2012) Available at US Food & Drug Administration website: http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.Label_ApprovalHistory#apphist (accessed 6 February 2013).
    • (2012)
  • 53
    • 84990326935 scopus 로고    scopus 로고
    • The effect of asenapine on health-related quality of life in patients with manic or mixed episodes associated with bipolar I disorder
    • Poster presented at the 2nd International Congress on Neurobiology, Psychopharmacology & Treatment Guidance, November 2011, Thessaloniki, Greece.
    • Sapin C Corson H Hansen K (2011) The effect of asenapine on health-related quality of life in patients with manic or mixed episodes associated with bipolar I disorder. Poster presented at the 2nd International Congress on Neurobiology, Psychopharmacology & Treatment Guidance, 24–27 November 2011, Thessaloniki, Greece.
    • (2011)
    • Sapin, C.1    Corson, H.2    Hansen, K.3
  • 54
    • 58649100010 scopus 로고    scopus 로고
    • Asenapine: A novel psychopharmacologic agent with a unique human receptor signature
    • Shahid M Walker GB Zorn SH. (2009) Asenapine: A novel psychopharmacologic agent with a unique human receptor signature. J Psychopharmacol 23: 65–73.
    • (2009) J Psychopharmacol , vol.23 , pp. 65-73
    • Shahid, M.1    Walker, G.B.2    Zorn, S.H.3
  • 55
    • 0036296061 scopus 로고    scopus 로고
    • Sexual dysfunction in patients taking conventional antipsychotic medication
    • Smith SM O’Keane V Murray R (2002) Sexual dysfunction in patients taking conventional antipsychotic medication. Br J Psychiatry 181: 49–55.
    • (2002) Br J Psychiatry , vol.181 , pp. 49-55
    • Smith, S.M.1    O’Keane, V.2    Murray, R.3
  • 56
    • 84990340458 scopus 로고    scopus 로고
    • Available at European Medicines Agency website: (accessed 6 February 2013).
    • Sycrest® Summary of Product Characteristics. (2012) Available at European Medicines Agency website: http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001177/human_med_001379.jsp&mid=WC0b01ac058001d124 (accessed 6 February 2013).
    • (2012)
  • 57
    • 33744495334 scopus 로고    scopus 로고
    • Atypical antipsychotics and pituitary tumors: A pharmacovigilance study
    • Szarfman A Tonning JM Levine JG. (2006) Atypical antipsychotics and pituitary tumors: A pharmacovigilance study. Pharmacotherapy 26: 748–758.
    • (2006) Pharmacotherapy , vol.26 , pp. 748-758
    • Szarfman, A.1    Tonning, J.M.2    Levine, J.G.3
  • 58
    • 84855345812 scopus 로고    scopus 로고
    • Asenapine as adjunctive treatment for acute mania associated with bipolar disorder: results of a 12-week core study and 40-week extension
    • Szegedi A Calabrese JR Stet L Apollo Study Group (2012) Asenapine as adjunctive treatment for acute mania associated with bipolar disorder: results of a 12-week core study and 40-week extension. J Clin Psychopharmacol 32: 46–55.
    • (2012) J Clin Psychopharmacol , vol.32 , pp. 46-55
    • Szegedi, A.1    Calabrese, J.R.2    Stet, L.3
  • 59
    • 79959252314 scopus 로고    scopus 로고
    • Effects of asenapine on depressive symptoms in patients with bipolar I disorder experiencing acute manic or mixed episodes: A post hoc analysis of two 3-week clinical trials
    • Szegedi A Zhao J van Willigenburg A (2011) Effects of asenapine on depressive symptoms in patients with bipolar I disorder experiencing acute manic or mixed episodes: A post hoc analysis of two 3-week clinical trials. BMC Psychiatry 11: 101.
    • (2011) BMC Psychiatry , vol.11 , pp. 101
    • Szegedi, A.1    Zhao, J.2    van Willigenburg, A.3
  • 60
    • 77950331526 scopus 로고    scopus 로고
    • Baseline characteristics and outcomes in patients with first episode or multiple episodes of acute mania
    • Tohen M Vieta E Gonzalez-Pinto A.; European Mania in Bipolar Longitudinal Evaluation of Medication (EMBLEM) Advisory Board (2010) Baseline characteristics and outcomes in patients with first episode or multiple episodes of acute mania. J Clin Psychiatry 71: 255–261.
    • (2010) J Clin Psychiatry , vol.71 , pp. 255-261
    • Tohen, M.1    Vieta, E.2    Gonzalez-Pinto, A.3
  • 61
    • 0041647134 scopus 로고    scopus 로고
    • The McLean-Harvard First-Episode Mania Study: Prediction of recovery and first recurrence
    • Tohen M Zarate CA Hennen J (2003) The McLean-Harvard First-Episode Mania Study: Prediction of recovery and first recurrence. Am J Psychiatry 160: 2099–2107.
    • (2003) Am J Psychiatry , vol.160 , pp. 2099-2107
    • Tohen, M.1    Zarate, C.A.2    Hennen, J.3
  • 62
    • 45149113072 scopus 로고    scopus 로고
    • Weight gain in bipolar disorder: Pharmacological treatment as a contributing factor
    • Torrent C Amann B Sánchez-Moreno J (2008) Weight gain in bipolar disorder: Pharmacological treatment as a contributing factor. Acta Psychiatr Scand 118: 4–18.
    • (2008) Acta Psychiatr Scand , vol.118 , pp. 4-18
    • Torrent, C.1    Amann, B.2    Sánchez-Moreno, J.3
  • 63
    • 79953031623 scopus 로고    scopus 로고
    • Bipolar mixed episodes and antidepressants: A cohort study of bipolar I disorder patients
    • Valentí M Pacchiarotti I Rosa AR (2011) Bipolar mixed episodes and antidepressants: A cohort study of bipolar I disorder patients. Bipolar Disord 13: 145–154.
    • (2011) Bipolar Disord , vol.13 , pp. 145-154
    • Valentí, M.1    Pacchiarotti, I.2    Rosa, A.R.3
  • 64
    • 70349285147 scopus 로고    scopus 로고
    • The expert consensus guideline series: Adherence problems in patients with serious and persistent mental illness
    • Velligan DI Weiden PJ Sajatovic M Expert Consensus Panel on Adherence Problems in Serious and Persistent Mental Illness (2009) The expert consensus guideline series: Adherence problems in patients with serious and persistent mental illness. J Clin Psychiatry 70: S1–S46.
    • (2009) J Clin Psychiatry , vol.70 , pp. S1-S46
    • Velligan, D.I.1    Weiden, P.J.2    Sajatovic, M.3
  • 65
    • 77955552307 scopus 로고    scopus 로고
    • Prevalence of mixed mania using 3 definitions
    • Vieta E Morralla C (2010) Prevalence of mixed mania using 3 definitions. J Affect Disord 125: 61–73.
    • (2010) J Affect Disord , vol.125 , pp. 61-73
    • Vieta, E.1    Morralla, C.2
  • 66
    • 84872674285 scopus 로고    scopus 로고
    • Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: Update 2013
    • Yatham LN Kennedy SH Parikh SV (2013) Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: Update 2013. Bipolar Disord 15: 1–44.
    • (2013) Bipolar Disord , vol.15 , pp. 1-44
    • Yatham, L.N.1    Kennedy, S.H.2    Parikh, S.V.3
  • 67
    • 84875670304 scopus 로고    scopus 로고
    • Early improvement predicts later outcome in manic or mixed episodes associated with bipolar I disorder: Post hoc analyses
    • Poster presented at 164th Annual Meeting of the American Psychiatric Association, 14–18 May, 2011, Honolulu, Hawaii
    • Zhao J Ha X Szegedi A (2011) Early improvement predicts later outcome in manic or mixed episodes associated with bipolar I disorder: Post hoc analyses. Poster presented at 164th Annual Meeting of the American Psychiatric Association, 14–18 May, 2011, Honolulu, Hawaii, USA.
    • (2011)
    • Zhao, J.1    Ha, X.2    Szegedi, A.3


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