Copy number alterations in small intestinal neuroendocrine tumors determined by array comparative genomic hybridization

BMC Cancer

Volumn 13, Issue , 2013, Pages

  Hashemi, Jamileh ^a   Fotouhi, Omid ^a   Sulaiman, Luqman ^a   Kjellman, Magnus ^a   Höög, Anders ^a   Zedenius, Jan ^a   Larsson, Catharina ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Array CGH; Carcinoid; Chromosome 18; Neuroendocrine tumor; Small intestine

Indexed keywords

ADULT; AGED; ARTICLE; CARCINOGENESIS; CHROMOSOME 11; CHROMOSOME 11Q; CHROMOSOME 14; CHROMOSOME 14Q; CHROMOSOME 16; CHROMOSOME 16Q; CHROMOSOME 18; CHROMOSOME 20; CHROMOSOME 20P; CHROMOSOME 20Q; CHROMOSOME 4; CHROMOSOME 5; CHROMOSOME 9; CHROMOSOME 9P; CHROMOSOME LOSS; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; COPY NUMBER VARIATION; FEMALE; GENETIC GAIN; HUMAN; HUMAN TISSUE; INTESTINE SURGERY; MAJOR CLINICAL STUDY; MALE; METASTASIS; NEUROENDOCRINE TUMOR; OVERALL SURVIVAL; POLYMERASE CHAIN REACTION; SMALL INTESTINAL NEUROENDOCRINE TUMOR; SMALL INTESTINE TUMOR;

ADULT; AGED; AGED, 80 AND OVER; CHROMOSOME ABERRATIONS; CHROMOSOME MAPPING; CLUSTER ANALYSIS; COMPARATIVE GENOMIC HYBRIDIZATION; DNA COPY NUMBER VARIATIONS; FEMALE; HUMANS; INTESTINAL NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM METASTASIS; NEUROENDOCRINE TUMORS; REPRODUCIBILITY OF RESULTS;

EID: 84886416018     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-505     Document Type: Article

References (41)

1. Jann H, Roll S, Couvelard A, Hentic O, Pavel M, Muller-Nordhorn J, Koch M, Rocken C, Rindi G, Ruszniewski P, et al. Neuroendocrine tumors of midgut and hindgut origin: tumor-node-metastasis classification determines clinical outcome. Cancer 2011, 117(15):3332-3341. 10.1002/cncr.25855, 21246527.
2. Kidd M, Modlin IM. Small intestinal neuroendocrine cell pathobiology: 'carcinoid' tumors. Curr Opin Oncol 2011, 23(1):45-52. 10.1097/CCO.0b013e328340d006, 21045686.
3. Modlin IM, Lye KD, Kidd M. A 5-decade analysis of 13,715 carcinoid tumors. Cancer 2003, 97(4):934-959. 10.1002/cncr.11105, 12569593.
4. Modlin IM, Oberg K, Chung DC, Jensen RT, de Herder WW, Thakker RV, Caplin M, Delle Fave G, Kaltsas GA, Krenning EP, et al. Gastroenteropancreatic neuroendocrine tumours. Lancet Oncol 2008, 9(1):61-72. 10.1016/S1470-2045(07)70410-2, 18177818.
5. Cunningham JL, de Diaz Stahl T, Sjoblom T, Westin G, Dumanski JP, Janson ET. Common pathogenetic mechanism involving human chromosome 18 in familial and sporadic ileal carcinoid tumors. Genes Chr & Cancer 2011, 50(2):82-94.
6. Järhult J, Landerholm K, Falkmer S, Nordenskjöld M, Sundler F, Wierup N. First report on metastasizing small bowel carcinoids in first-degree relatives in three generations. Neuroendocrinology 2010, 91(4):318-323. 10.1159/000299790, 20460879.
7. Modlin IM, Kidd M, Latich I, Zikusoka MN, Shapiro MD. Current status of gastrointestinal carcinoids. Gastroenterology 2005, 128(6):1717-1751. 10.1053/j.gastro.2005.03.038, 15887161.
8. Moertel CG. Treatment of the carcinoid tumor and the malignant carcinoid syndrome. J Clin Oncol 1983, 1(11):727-740.
9. Caplin ME, Buscombe JR, Hilson AJ, Jones AL, Watkinson AF, Burroughs AK. Carcinoid tumour. Lancet 1998, 352(9130):799-805. 10.1016/S0140-6736(98)02286-7, 9737302.
10. de Herder WW. Tumours of the midgut (jejunum, ileum and ascending colon, including carcinoid syndrome). Best Pract & Res Clin gastroenterol 2005, 19(5):705-715. 10.1016/j.bpg.2005.05.007, 16253895.
11. Yao JC, Hassan M, Phan A, Dagohoy C, Leary C, Mares JE, Abdalla EK, Fleming JB, Vauthey JN, Rashid A, et al. One hundred years after "carcinoid" : epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States. J Clin Oncol 2008, 26(18):3063-3072. 10.1200/JCO.2007.15.4377, 18565894.
12. Kytölä S, Höög A, Nord B, Cedermark B, Frisk T, Larsson C, Kjellman M. Comparative genomic hybridization identifies loss of 18q22-qter as an early and specific event in tumorigenesis of midgut carcinoids. Am J Pathol 2001, 158(5):1803-1808. 10.1016/S0002-9440(10)64136-3, 1891959, 11337378.
13. Zhao J, de Krijger RR, Meier D, Speel EJ, Saremaslani P, Muletta-Feurer S, Matter C, Roth J, Heitz PU, Komminoth P. Genomic alterations in well-differentiated gastrointestinal and bronchial neuroendocrine tumors (carcinoids): marked differences indicating diversity in molecular pathogenesis. Am J Pathol 2000, 157(5):1431-1438. 10.1016/S0002-9440(10)64780-3, 1885722, 11073802.
14. Löllgen RM, Hessman O, Szabo E, Westin G, Åkerstrom G. Chromosome 18 deletions are common events in classical midgut carcinoid tumors. Int J Cancer 2001, 92(6):812-815. 10.1002/ijc.1276, 11351300.
15. Andersson E, Swärd C, Stenman G, Ahlman H, Nilsson O. High-resolution genomic profiling reveals gain of chromosome 14 as a predictor of poor outcome in ileal carcinoids. Endocr Relat Cancer 2009, 16(3):953-966. 10.1677/ERC-09-0052, 19458023.
16. Kulke MH, Freed E, Chiang DY, Philips J, Zahrieh D, Glickman JN, Shivdasani RA. High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss. Genes Chr & Cancer 2008, 47(7):591-603.
17. Walsh KM, Choi M, Oberg K, Kulke MH, Yao JC, Wu C, Jurkiewicz M, Hsu LI, Hooshmand SM, Hassan M, et al. A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum. Endocr Relat Cancer 2011, 18(1):171-180. 10.1677/ERC-10-0248, 3221459, 21139019.
18. Klöppel G, Couvelard A, Perren A, Komminoth P, McNicol AM, Nilsson O, Scarpa A, Scoazec JY, Wiedenmann B, Papotti M, et al. ENETS consensus guidelines for the standards of care in neuroendocrine tumors: towards a standardized approach to the diagnosis of gastroenteropancreatic neuroendocrine tumors and their prognostic stratification. Neuroendocrinology 2009, 90(2):162-166. 10.1159/000182196, 19060454.
19. Rindi G, Bordi C, La Rosa S, Solcia E, Delle Fave G, Gruppo Italiano Patologi Apparato D, Societa Italiana di Anatomia Patologica e Citopatologia Diagnostica/International Academy of Pathology Id Gastroenteropancreatic (neuro)endocrine neoplasms: the histology report. Dig liver Dis 2011, 43(Suppl 4):S356-S360. Gruppo Italiano Patologi Apparato D, Societa Italiana di Anatomia Patologica e Citopatologia Diagnostica/International Academy of Pathology Id.
20. Weng WH, Claviez A, Krams M, Hashemi J, Larsson O, Larsson C, Suttorp M. A 10-year-old girl with bifocal synovial sarcoma. Lancet Oncol 2006, 7(7):605-607. 10.1016/S1470-2045(06)70762-8, 16814213.
21. Hashemi J, Worrall C, Vasilcanu D, Fryknas M, Sulaiman L, Karimi M, Weng WH, Lui WO, Rudduck C, Axelson M, et al. Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP). PLoS One 2011, 6(3):e14757. 10.1371/journal.pone.0014757, 3056661, 21423728.
22. Saal LH, Troein C, Vallon-Christersson J, Gruvberger S, Borg A, Peterson C. Bioarray software environment (BASE): a platform for comprehensive management and analysis of microarray data. Genome Biol 2002, 3(8):1-0003.6. SOFTWARE0003.
23. Rouveirol C, Stransky N, Hupe P, Rosa PL, Viara E, Barillot E, Radvanyi F. Computation of recurrent minimal genomic alterations from array-CGH data. Bioinformatics 2006, 22(7):849-856. 10.1093/bioinformatics/btl004, 16434445.
24. Saeed AI, Sharov V, White J, Li J, Liang W, Bhagabati N, Braisted J, Klapa M, Currier T, Thiagarajan M, et al. TM4: a free, open-source system for microarray data management and analysis. Biotechniques 2003, 34(2):374-378.
25. do Kim H, Nagano Y, Choi IS, White JA, Yao JC, Rashid A. Allelic alterations in well-differentiated neuroendocrine tumors (carcinoid tumors) identified by genome-wide single nucleotide polymorphism analysis and comparison with pancreatic endocrine tumors. Genes, Chr & Cancer 2008, 47(1):84-92.
26. Banck MS, Kanwar R, Kulkarni AA, Boora GK, Metge F, Kipp BR, Zhang L, Thorland EC, Minn KT, Tentu R, et al. The genomic landscape of small intestine neuroendocrine tumors. J clin Invest 2013, 123(6):2502-2508. 10.1172/JCI67963, 3668835, 23676460.
27. Mongiat M, Ligresti G, Marastoni S, Lorenzon E, Doliana R, Colombatti A. Regulation of the extrinsic apoptotic pathway by the extracellular matrix glycoprotein EMILIN2. Mol and Cell Biol 2007, 27(20):7176-7187.
28. Hill VK, Hesson LB, Dansranjavin T, Dallol A, Bieche I, Vacher S, Tommasi S, Dobbins T, Gentle D, Euhus D, et al. Identification of 5 novel genes methylated in breast and other epithelial cancers. Molecular cancer 2010, 9:51. 10.1186/1476-4598-9-51, 2841122, 20205715.
29. Messahel B, Williams R, Ridolfi A, A'Hern R, Warren W, Tinworth L, Hobson R, Al-Saadi R, Whyman G, Brundler MA, et al. Allele loss at 16q defines poorer prognosis Wilms tumour irrespective of treatment approach in the UKW1-3 clinical trials: a children's cancer and leukaemia group (CCLG) Study. Eur J Cancer 2009, 45(5):819-826. 10.1016/j.ejca.2009.01.005, 19231157.
30. Hajra KM, Fearon ER. Cadherin and catenin alterations in human cancer. Genes, Chr & Cancer 2002, 34(3):255-268.
31. Moran CJ, Joyce M, McAnena OJ. CDH1 associated gastric cancer: a report of a family and review of the literature. EJSO 2005, 31(3):259-264. 10.1016/j.ejso.2004.12.010, 15780560.
32. Edstrom E, Mahlamaki E, Nord B, Kjellman M, Karhu R, Hoog A, Goncharov N, Teh BT, Backdahl M, Larsson C. Comparative genomic hybridization reveals frequent losses of chromosomes 1p and 3q in pheochromocytomas and abdominal paragangliomas, suggesting a common genetic etiology. Am J Pathol 2000, 156(2):651-659. 10.1016/S0002-9440(10)64769-4, 1850024, 10666394.
33. Ambatipudi S, Gerstung M, Gowda R, Pai P, Borges AM, Schäffer AA, Beerenwinkel N, Mahimkar MB. Genomic profiling of advanced-stage oral cancers reveals chromosome 11q alterations as markers of poor clinical outcome. PLoS One 2011, 6(2):e17250. 10.1371/journal.pone.0017250, 3046132, 21386901.
34. Spitz R, Hero B, Simon T, Berthold F. Loss in chromosome 11q identifies tumors with increased risk for metastatic relapses in localized and 4S neuroblastoma. Clin Cancer Res 2006, 12(11 Pt 1):3368-3373.
35. Giaretti W, Maffei M, Pentenero M, Scaruffi P, Donadini A, Di Nallo E, Malacarne D, Marino R, Familiari U, Coco S, et al. Genomic aberrations in normal appearing mucosa fields distal from oral potentially malignant lesions. Cell Oncol 2012, 35(1):43-52.
36. Bae JS, Choi JS, Baik SH, Park WC, Song BJ, Kim JS, Lim Y, Jung SS. Genomic alterations of primary tumor and blood in invasive ductal carcinoma of breast. World J Surg Oncol 2010, 8:32. 10.1186/1477-7819-8-32, 2865462, 20409316.
37. Buffart TE, van Grieken NC, Tijssen M, Coffa J, Ylstra B, Grabsch HI, van de Velde CJ, Carvalho B, Meijer GA. High resolution analysis of DNA copy-number aberrations of chromosomes 8, 13, and 20 in gastric cancers. Virchows Arch 2009, 455(3):213-223. 10.1007/s00428-009-0814-y, 2744787, 19697059.
38. Tabach Y, Kogan-Sakin I, Buganim Y, Solomon H, Goldfinger N, Hovland R, Ke XS, Oyan AM, Kalland KH, Rotter V, et al. Amplification of the 20q chromosomal arm occurs early in tumorigenic transformation and may initiate cancer. PLoS One 2011, 6(1):e14632. 10.1371/journal.pone.0014632, 3031497, 21297939.
39. Bai C, Connolly B, Metzker ML, Hilliard CA, Liu X, Sandig V, Soderman A, Galloway SM, Liu Q, Austin CP, et al. Overexpression of M68/DcR3 in human gastrointestinal tract tumors independent of gene amplification and its location in a four-gene cluster. Proc Natl Acad Sci U S A 2000, 97(3):1230-1235. 10.1073/pnas.97.3.1230, 15578, 10655513.
40. Liang QL, Wang BR, Li GH. DcR3 and survivin are highly expressed in colorectal carcinoma and closely correlated to its clinicopathologic parameters. J Zhejiang Univ Sci B 2009, 10(9):675-682. 10.1631/jzus.B0920077, 2738837, 19735100.
41. Wu Y, Guo E, Yu J, Xie Q. High DcR3 expression predicts stage pN2-3 in gastric cancer. Am J Clin Oncol 2008, 31(1):79-83. 10.1097/COC.0b013e3180ca77ad, 18376232.