메뉴 건너뛰기




Volumn 6, Issue 3, 2011, Pages

Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; LIPOFECTAMINE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PICROPODOPHYLLIN; PROTEIN BCL 2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; DRUG DERIVATIVE; MYC PROTEIN; PODOPHYLLOTOXIN;

EID: 79952685382     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014757     Document Type: Article
Times cited : (20)

References (41)
  • 1
    • 13644254794 scopus 로고    scopus 로고
    • Molecular mechanisms of drug resistance
    • Longley DB, Johnston PG, (2005) Molecular mechanisms of drug resistance. J Pathol 205: 275-292.
    • (2005) J Pathol , vol.205 , pp. 275-292
    • Longley, D.B.1    Johnston, P.G.2
  • 2
    • 33646128506 scopus 로고    scopus 로고
    • Epigenetics as a mechanism driving polygenic clinical drug resistance
    • Glasspool RM, Teodoridis JM, Brown R, (2006) Epigenetics as a mechanism driving polygenic clinical drug resistance. Br J Cancer 94: 1087-1092.
    • (2006) Br J Cancer , vol.94 , pp. 1087-1092
    • Glasspool, R.M.1    Teodoridis, J.M.2    Brown, R.3
  • 3
    • 33646371709 scopus 로고    scopus 로고
    • Multiple genetic and epigenetic interacting mechanisms contribute to clonally selection of drug-resistant tumors: current views and new therapeutic prospective
    • Roberti A, La Sala D, Cinti C, (2006) Multiple genetic and epigenetic interacting mechanisms contribute to clonally selection of drug-resistant tumors: current views and new therapeutic prospective. J Cell Physiol 207: 571-581.
    • (2006) J Cell Physiol , vol.207 , pp. 571-581
    • Roberti, A.1    la Sala, D.2    Cinti, C.3
  • 4
    • 33847347345 scopus 로고    scopus 로고
    • Epigenetic markers and response to chemotherapy in cancer
    • Strathdee G, (2007) Epigenetic markers and response to chemotherapy in cancer. Dis Markers 23: 43-49.
    • (2007) Dis Markers , vol.23 , pp. 43-49
    • Strathdee, G.1
  • 5
    • 31944447676 scopus 로고    scopus 로고
    • Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer
    • Pang ST, Weng WH, Flores-Morales A, Johansson B, Pourian MR, et al. (2006) Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer. Prostate 66: 157-172.
    • (2006) Prostate , vol.66 , pp. 157-172
    • Pang, S.T.1    Weng, W.H.2    Flores-Morales, A.3    Johansson, B.4    Pourian, M.R.5
  • 6
    • 73449113932 scopus 로고    scopus 로고
    • Role of microRNA in anticancer drug resistance
    • Zheng T, Wang J, Chen X, Liu L, (2010) Role of microRNA in anticancer drug resistance. Int J Cancer 126: 2-10.
    • (2010) Int J Cancer , vol.126 , pp. 2-10
    • Zheng, T.1    Wang, J.2    Chen, X.3    Liu, L.4
  • 7
    • 33745100153 scopus 로고    scopus 로고
    • The insulin-like growth factor-1 receptor inhibitor PPP produces only very limited resistance in tumor cells exposed to long-term selection
    • Vasilcanu D, Weng WH, Girnita A, Lui WO, Vasilcanu R, et al. (2006) The insulin-like growth factor-1 receptor inhibitor PPP produces only very limited resistance in tumor cells exposed to long-term selection. Oncogene 25: 3186-3195.
    • (2006) Oncogene , vol.25 , pp. 3186-3195
    • Vasilcanu, D.1    Weng, W.H.2    Girnita, A.3    Lui, W.O.4    Vasilcanu, R.5
  • 8
    • 1642494838 scopus 로고    scopus 로고
    • Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth
    • Girnita A, Girnita L, del Prete F, Bartolazzi A, Larsson O, et al. (2004) Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth. Cancer Res 64: 236-242.
    • (2004) Cancer Res , vol.64 , pp. 236-242
    • Girnita, A.1    Girnita, L.2    del Prete, F.3    Bartolazzi, A.4    Larsson, O.5
  • 9
    • 34548699650 scopus 로고    scopus 로고
    • Targeting the IGF-1R using picropodophyllin in the therapeutical 5T2MM mouse model of multiple myeloma: beneficial effects on tumor growth, angiogenesis, bone disease and survival
    • Menu E, Jernberg-Wiklund H, De Raeve H, De Leenheer E, Coulton L, et al. (2007) Targeting the IGF-1R using picropodophyllin in the therapeutical 5T2MM mouse model of multiple myeloma: beneficial effects on tumor growth, angiogenesis, bone disease and survival. Int J Cancer 121: 1857-1861.
    • (2007) Int J Cancer , vol.121 , pp. 1857-1861
    • Menu, E.1    Jernberg-Wiklund, H.2    de Raeve, H.3    de Leenheer, E.4    Coulton, L.5
  • 10
    • 30444446821 scopus 로고    scopus 로고
    • Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model
    • Menu E, Jernberg-Wiklund H, Stromberg T, De Raeve H, Girnita L, et al. (2006) Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model. Blood 107: 655-660.
    • (2006) Blood , vol.107 , pp. 655-660
    • Menu, E.1    Jernberg-Wiklund, H.2    Stromberg, T.3    de Raeve, H.4    Girnita, L.5
  • 11
    • 47149111583 scopus 로고    scopus 로고
    • Autocrine insulin-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis
    • Nussbaum T, Samarin J, Ehemann V, Bissinger M, Ryschich E, et al. (2008) Autocrine insulin-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis. Hepatology 48: 146-156.
    • (2008) Hepatology , vol.48 , pp. 146-156
    • Nussbaum, T.1    Samarin, J.2    Ehemann, V.3    Bissinger, M.4    Ryschich, E.5
  • 12
    • 68849090494 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines
    • Duan Z, Choy E, Harmon D, Yang C, Ryu K, et al. (2009) Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines. Mol Cancer Ther 8: 2122-2130.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2122-2130
    • Duan, Z.1    Choy, E.2    Harmon, D.3    Yang, C.4    Ryu, K.5
  • 13
  • 14
    • 75749094341 scopus 로고    scopus 로고
    • Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma
    • Yin S, Girnita A, Stromberg T, Khan Z, Andersson S, et al. (2010) Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma. Neuro Oncol 12: 19-27.
    • (2010) Neuro Oncol , vol.12 , pp. 19-27
    • Yin, S.1    Girnita, A.2    Stromberg, T.3    Khan, Z.4    Andersson, S.5
  • 15
    • 47249164297 scopus 로고    scopus 로고
    • Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor
    • Economou MA, Wu J, Vasilcanu D, Rosengren L, All-Ericsson C, et al. (2008) Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor. Invest Ophthalmol Vis Sci 49: 2620-2626.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 2620-2626
    • Economou, M.A.1    Wu, J.2    Vasilcanu, D.3    Rosengren, L.4    All-Ericsson, C.5
  • 16
    • 47249143238 scopus 로고    scopus 로고
    • Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma
    • Economou MA, Andersson S, Vasilcanu D, All-Ericsson C, Menu E, et al. (2008) Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma. Invest Ophthalmol Vis Sci 49: 2337-2342.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 2337-2342
    • Economou, M.A.1    Andersson, S.2    Vasilcanu, D.3    All-Ericsson, C.4    Menu, E.5
  • 17
    • 79952642505 scopus 로고    scopus 로고
    • Insulin-like growth factor type-I receptor (IGF-1R) dependent phosphorylation of ERK1/2 but not Akt (PKB) can be induced by picropodophyllin
    • Vasilcanu R, Vasilcanu D, Sehat B, Yin S, Girnita A, et al. (2007) Insulin-like growth factor type-I receptor (IGF-1R) dependent phosphorylation of ERK1/2 but not Akt (PKB) can be induced by picropodophyllin. Mol Pharmacol.
    • (2007) Mol Pharmacol
    • Vasilcanu, R.1    Vasilcanu, D.2    Sehat, B.3    Yin, S.4    Girnita, A.5
  • 18
    • 33845910166 scopus 로고    scopus 로고
    • Insulin-like growth factor-I is an important antiapoptotic factor for rat leydig cells during postnatal development
    • Colon E, Zaman F, Axelson M, Larsson O, Carlsson-Skwirut C, et al. (2007) Insulin-like growth factor-I is an important antiapoptotic factor for rat leydig cells during postnatal development. Endocrinology 148: 128-139.
    • (2007) Endocrinology , vol.148 , pp. 128-139
    • Colon, E.1    Zaman, F.2    Axelson, M.3    Larsson, O.4    Carlsson-Skwirut, C.5
  • 19
    • 33947265626 scopus 로고    scopus 로고
    • In the absence of IGF-1 signaling, IFN-gamma suppresses human malignant T-cell growth
    • Conti L, Regis G, Longo A, Bernabei P, Chiarle R, et al. (2007) In the absence of IGF-1 signaling, IFN-gamma suppresses human malignant T-cell growth. Blood 109: 2496-2504.
    • (2007) Blood , vol.109 , pp. 2496-2504
    • Conti, L.1    Regis, G.2    Longo, A.3    Bernabei, P.4    Chiarle, R.5
  • 20
    • 0030804305 scopus 로고    scopus 로고
    • Synthetic peptides derived from the melanocyte-stimulating hormone receptor MC1R can stimulate HLA-A2-restricted cytotoxic T lymphocytes that recognize naturally processed peptides on human melanoma cells
    • Salazar-Onfray F, Nakazawa T, Chhajlani V, Petersson M, Karre K, et al. (1997) Synthetic peptides derived from the melanocyte-stimulating hormone receptor MC1R can stimulate HLA-A2-restricted cytotoxic T lymphocytes that recognize naturally processed peptides on human melanoma cells. Cancer Res 57: 4348-4355.
    • (1997) Cancer Res , vol.57 , pp. 4348-4355
    • Salazar-Onfray, F.1    Nakazawa, T.2    Chhajlani, V.3    Petersson, M.4    Karre, K.5
  • 22
    • 0342313465 scopus 로고    scopus 로고
    • Chromosomal alterations in 15 breast cancer cell lines by comparative genomic hybridization and spectral karyotyping
    • Kytola S, Rummukainen J, Nordgren A, Karhu R, Farnebo F, et al. (2000) Chromosomal alterations in 15 breast cancer cell lines by comparative genomic hybridization and spectral karyotyping. Genes Chromosomes Cancer 28: 308-317.
    • (2000) Genes Chromosomes Cancer , vol.28 , pp. 308-317
    • Kytola, S.1    Rummukainen, J.2    Nordgren, A.3    Karhu, R.4    Farnebo, F.5
  • 24
    • 21644473873 scopus 로고    scopus 로고
    • Loss of chromosome 13q is a frequently acquired event in genetic progression of soft tissue sarcomas in the abdominal cavity
    • Weng WH, Lerner M, Grander D, Ahlen J, Villablanca A, et al. (2005) Loss of chromosome 13q is a frequently acquired event in genetic progression of soft tissue sarcomas in the abdominal cavity. Int J Oncol 26: 5-16.
    • (2005) Int J Oncol , vol.26 , pp. 5-16
    • Weng, W.H.1    Lerner, M.2    Grander, D.3    Ahlen, J.4    Villablanca, A.5
  • 25
    • 34247479418 scopus 로고    scopus 로고
    • High-resolution genomic profiles of breast cancer cell lines assessed by tiling BAC array comparative genomic hybridization
    • Jonsson G, Staaf J, Olsson E, Heidenblad M, Vallon-Christersson J, et al. (2007) High-resolution genomic profiles of breast cancer cell lines assessed by tiling BAC array comparative genomic hybridization. Genes Chromosomes Cancer 46: 543-558.
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 543-558
    • Jonsson, G.1    Staaf, J.2    Olsson, E.3    Heidenblad, M.4    Vallon-Christersson, J.5
  • 26
    • 0037099005 scopus 로고    scopus 로고
    • BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data
    • SOFTWARE0003
    • Saal LH, Troein C, Vallon-Christersson J, Gruvberger S, Borg A, et al. (2002) BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data. Genome Biol 3: SOFTWARE0003.
    • (2002) Genome Biol , vol.3
    • Saal, L.H.1    Troein, C.2    Vallon-Christersson, J.3    Gruvberger, S.4    Borg, A.5
  • 27
    • 0035841226 scopus 로고    scopus 로고
    • A statistical method for flagging weak spots improves normalization and ratio estimates in microarrays
    • Yang MC, Ruan QG, Yang JJ, Eckenrode S, Wu S, et al. (2001) A statistical method for flagging weak spots improves normalization and ratio estimates in microarrays. Physiol Genomics 7: 45-53.
    • (2001) Physiol Genomics , vol.7 , pp. 45-53
    • Yang, M.C.1    Ruan, Q.G.2    Yang, J.J.3    Eckenrode, S.4    Wu, S.5
  • 28
    • 1342294092 scopus 로고    scopus 로고
    • Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation
    • Yang YH, Dudoit S, Luu P, Lin DM, Peng V, et al. (2002) Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res 30: e15.
    • (2002) Nucleic Acids Res , vol.30
    • Yang, Y.H.1    Dudoit, S.2    Luu, P.3    Lin, D.M.4    Peng, V.5
  • 30
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da W, Sherman BT, Lempicki RA, (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • da Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 31
    • 33744938449 scopus 로고    scopus 로고
    • LUMA (LUminometric Methylation Assay)--a high throughput method to the analysis of genomic DNA methylation
    • Karimi M, Johansson S, Stach D, Corcoran M, Grander D, et al. (2006) LUMA (LUminometric Methylation Assay)--a high throughput method to the analysis of genomic DNA methylation. Exp Cell Res 312: 1989-1995.
    • (2006) Exp Cell Res , vol.312 , pp. 1989-1995
    • Karimi, M.1    Johansson, S.2    Stach, D.3    Corcoran, M.4    Grander, D.5
  • 32
    • 0022820770 scopus 로고
    • Chromosome 8 breakpoint far 3′ of the c-myc oncogene in a Burkitt's lymphoma 2;8 variant translocation is equivalent to the murine pvt-1 locus
    • Graham M, Adams JM, (1986) Chromosome 8 breakpoint far 3′ of the c-myc oncogene in a Burkitt's lymphoma 2;8 variant translocation is equivalent to the murine pvt-1 locus. EMBO J 5: 2845-2851.
    • (1986) EMBO J , vol.5 , pp. 2845-2851
    • Graham, M.1    Adams, J.M.2
  • 34
    • 0030822196 scopus 로고    scopus 로고
    • Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins
    • Alevizopoulos K, Vlach J, Hennecke S, Amati B, (1997) Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins. Embo J 16: 5322-5333.
    • (1997) Embo J , vol.16 , pp. 5322-5333
    • Alevizopoulos, K.1    Vlach, J.2    Hennecke, S.3    Amati, B.4
  • 35
    • 16844371813 scopus 로고    scopus 로고
    • Immortalization of primary human prostate epithelial cells by c-Myc
    • Gil J, Kerai P, Lleonart M, Bernard D, Cigudosa JC, et al. (2005) Immortalization of primary human prostate epithelial cells by c-Myc. Cancer Res 65: 2179-2185.
    • (2005) Cancer Res , vol.65 , pp. 2179-2185
    • Gil, J.1    Kerai, P.2    Lleonart, M.3    Bernard, D.4    Cigudosa, J.C.5
  • 36
    • 44849129491 scopus 로고    scopus 로고
    • Failure of CDKN2A/B (INK4A/B-ARF)-mediated tumor suppression and resistance to targeted therapy in acute lymphoblastic leukemia induced by BCR-ABL
    • Mullighan CG, Williams RT, Downing JR, Sherr CJ, (2008) Failure of CDKN2A/B (INK4A/B-ARF)-mediated tumor suppression and resistance to targeted therapy in acute lymphoblastic leukemia induced by BCR-ABL. Genes Dev 22: 1411-1415.
    • (2008) Genes Dev , vol.22 , pp. 1411-1415
    • Mullighan, C.G.1    Williams, R.T.2    Downing, J.R.3    Sherr, C.J.4
  • 37
    • 0013962973 scopus 로고
    • The podophyllotoxin-picropodophyllin equilibrium
    • Gensler WJ, Gatsonis CD, (1966) The podophyllotoxin-picropodophyllin equilibrium. J Org Chem 31: 3224-3227.
    • (1966) J Org Chem , vol.31 , pp. 3224-3227
    • Gensler, W.J.1    Gatsonis, C.D.2
  • 38
    • 45849151309 scopus 로고    scopus 로고
    • Identification of cytochrome c oxidase subunit 6A1 as a suppressor of Bax-induced cell death by yeast-based functional screening
    • Eun SY, Woo IS, Jang HS, Jin H, Kim MY, et al. (2008) Identification of cytochrome c oxidase subunit 6A1 as a suppressor of Bax-induced cell death by yeast-based functional screening. Biochem Biophys Res Commun 373: 58-63.
    • (2008) Biochem Biophys Res Commun , vol.373 , pp. 58-63
    • Eun, S.Y.1    Woo, I.S.2    Jang, H.S.3    Jin, H.4    Kim, M.Y.5
  • 39
    • 0034692430 scopus 로고    scopus 로고
    • Role of the insulin-like growth factor family in cancer development and progression
    • Yu H, Rohan T, (2000) Role of the insulin-like growth factor family in cancer development and progression. J Natl Cancer Inst 92: 1472-1489.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1472-1489
    • Yu, H.1    Rohan, T.2
  • 40
    • 0030909657 scopus 로고    scopus 로고
    • Specific inhibition of insulin-like growth factor-1 and insulin receptor tyrosine kinase activity and biological function by tyrphostins
    • Parrizas M, Gazit A, Levitzki A, Wertheimer E, LeRoith D, (1997) Specific inhibition of insulin-like growth factor-1 and insulin receptor tyrosine kinase activity and biological function by tyrphostins. Endocrinology 138: 1427-1433.
    • (1997) Endocrinology , vol.138 , pp. 1427-1433
    • Parrizas, M.1    Gazit, A.2    Levitzki, A.3    Wertheimer, E.4    LeRoith, D.5
  • 41
    • 0032827420 scopus 로고    scopus 로고
    • Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis
    • Peruzzi F, Prisco M, Dews M, Salomoni P, Grassilli E, et al. (1999) Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis. Mol Cell Biol 19: 7203-7215.
    • (1999) Mol Cell Biol , vol.19 , pp. 7203-7215
    • Peruzzi, F.1    Prisco, M.2    Dews, M.3    Salomoni, P.4    Grassilli, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.