Allele loss at 16q defines poorer prognosis Wilms tumour irrespective of treatment approach in the UKW1-3 clinical trials: A Children's Cancer and Leukaemia Group (CCLG) study

European Journal of Cancer

Volumn 45, Issue 5, 2009, Pages 819-826

  Messahel, Boo ^a   Williams, Richard ^a   Ridolfi, Antonia ^a   A'Hern, Roger ^a   Warren, William ^a   Tinworth, Lorna ^b   Hobson, Rachel ^c   Al Saadi, Reem ^a   Whyman, Gavin ^c   Brundler, Marie Anne ^d   Kelsey, Anna ^e   Sebire, Neil ^f   Jones, Chris ^a   Vujanic, Gordan ^g   Pritchard Jones, Kathy ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b ST GEORGE S HOSPITAL   (United Kingdom)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

^d BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

^e ROYAL MANCHESTER CHILDREN S HOSPITAL   (United Kingdom)

^f GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^g UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

Author keywords

Childhood cancer; Loss of heterozygosity (LOH); Renal tumours

Indexed keywords

DACTINOMYCIN; DOXORUBICIN; VINCRISTINE;

ALLELE; ARTICLE; CANCER CHEMOTHERAPY; CANCER MORTALITY; CANCER RELAPSE; CANCER SURVIVAL; CHILD; CHROMOSOME 16Q; CHROMOSOME 1P; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE LOCUS; GENE LOSS; HETEROZYGOSITY LOSS; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INFANT; MAJOR CLINICAL STUDY; MULTIVARIATE ANALYSIS; NEPHRECTOMY; NEPHROBLASTOMA; NEWBORN; OVERALL SURVIVAL; POLYMERASE CHAIN REACTION; PREOPERATIVE TREATMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGNOSIS; RISK ASSESSMENT; RISK FACTOR;

CHEMOTHERAPY, ADJUVANT; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 16; HUMANS; INFANT; INFANT, NEWBORN; KIDNEY NEOPLASMS; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; NEOADJUVANT THERAPY; NEOPLASM STAGING; NEPHRECTOMY; POLYMERASE CHAIN REACTION; PROGNOSIS; SURVIVAL ANALYSIS; TREATMENT OUTCOME; WILMS TUMOR;

EID: 61349156711     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2009.01.005     Document Type: Article

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