Metformin Attenuates the Exacerbation of the Allergic Eosinophilic Inflammation in High Fat-Diet-Induced Obesity in Mice

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Calixto, Marina Ciarallo ^a   Lintomen, Letícia ^a   André, Diana Majoli ^a   Leiria, Luiz Osório ^a   Ferreira, Danilo ^a   Lellis Santos, Camilo ^b   Anhê, Gabriel Forato ^a   Bordin, Silvana ^b   Landgraf, Richardt Gama ^c   Antunes, Edson ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; AMINOGUANIDINE; EOTAXIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; METFORMIN; NITRIC OXIDE; OVALBUMIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ALLERGIC EOSINOPHILIC INFLAMMATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CELL INFILTRATION; CONTROLLED STUDY; DISEASE EXACERBATION; DRUG MECHANISM; EOSINOPHIL; INFLAMMATION; INSULIN RESISTANCE; LIPID DIET; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; OBESITY; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ASTHMA; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; DIET, HIGH-FAT; ENZYME INHIBITORS; EOSINOPHILS; GUANIDINES; HYPOGLYCEMIC AGENTS; INFLAMMATION; INSULIN RESISTANCE; LUNG; MALE; METFORMIN; MICE; MICE, INBRED C57BL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OBESITY; OVALBUMIN; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84886304307     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076786     Document Type: Article

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