The chitinase-like protein YKL-40 increases mucin5AC production in human bronchial epithelial cells

Experimental Cell Research

Volumn 319, Issue 18, 2013, Pages 2866-2873

  Liu, Chunyi ^a   Li, Qi ^a   Zhou, Xiangdong ^a   Kolosov, Victor P ^b   Perelman, Juliy M ^b  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b Russian Academy of Medical Sciences   (Russian Federation)

Author keywords

Extracellular signal regulated kinase; Focal adhesion kinase; Mucin5AC; Nuclear factor B; Protease activating receptor 2; YKL 40

Indexed keywords

FOCAL ADHESION KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MUCIN 5AC; PROTEIN; PROTEIN YKL 40; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; BRONCHUS; CHRONIC INFLAMMATION; CHRONIC RESPIRATORY TRACT DISEASE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; WESTERN BLOTTING;

EID: 84886303345     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2013.08.009     Document Type: Article

References (33)

1. Williams O.W., Sharafkhaneh A., Kim V., Dickey B.F., Evans C.M. Airway mucus: from production to secretion. Am. J. Respir. Cell Mol. Biol. 2006, 34(5):527-536.
2. Davis C.W., Dickey B.F. Regulated airway goblet cell mucin secretion. Annu. Rev. Physiol. 2008, 70:487-512.
3. Rogers D.F. Physiology of airway mucus secretion and pathophysiology of hypersecretion. Respir. Care 2007, 52(9):1134-1146.
4. Evans C.M., Kim K., Tuvim M.J., Dickey B.F. Mucus hypersecretion in asthma: causes and effects. Curr. Opin. Pulm. Med. 2009, 15(1):4-11.
5. Kuyper L.M., Paré P.D., Hogg J.C., Lambert R.K., Ionescu D., Woods R., Bai T.R. Characterization of airway plugging in fatal asthma. Am. J. Med. 2003, 115(1):6-11.
6. Funkhouser J.D., Jr.N.N Aronson, Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family. BMC Evol. Biol. 2007, 7:96.
7. Kawada M., Hachiya Y., Arihiro A., Mizoguchi E. Role of mammalian chitinases in inflammatory conditions. Keio J. Med. 2007, 56(1):21-27.
8. Lee C.G., Da.Silva C.A., Dela.Cruz C.S., Ahangari F., Ma B., Kang M.J., He C.H., Takyar S., Elias J.A. Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury. Annu. Rev. Physiol. 2011, 73:479-501.
9. Park J.A., Drazen J.M., Tschumperlin D.J. The chitinase-like protein YKL-40 is secreted by airway epithelial cells at base line and in response to compressive mechanical stress. J. Biol. Chem 2010, 285(39):29817-29825.
10. Lee C.G., Hartl D., Lee G.R., Koller B., Matsuura H., Da Silva C.A., Sohn M.H., Cohn L., Homer R.J., Kozhich A.A., Humbles A., Kearley J., Coyle A., Chupp G., Reed J., Flavell R.A., Elias J.A. Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J. Exp. Med. 2009, 206(5):1149-1166.
11. Reese T.A., Liang H.E., Tager A.M, Luster A.D., Van Rooijen N., Voehringer D., Locksley R.M. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 2007, 447(7140):92-96.
12. Guan S.P., Mok Y.K., Koo K.N., Chu K.L., Wong W.S. Chitinases: biomarkers for human diseases. Protein Pept. Lett 2009, 16(5):490-498.
13. Hartl D., Lee C.G., Da Silva C.A., Chupp G.L., Elias J.A. Novel biomarkers in asthma: chemokines and chitinase-like proteins. Curr. Opin. Allergy Clin. Immunol. 2009, 9(1):60-66.
14. Létuvé S., Kozhich A., Arouche N., Grandsaigne M., Reed J., Dombret M.C., Kiener P.A., Aubier M., Coyle A.J., Pretolani M. YKL-40 is elevated in patients with chronic obstructive pulmonary disease and activates alveolar marcophages. J. Immunol. 2008, 187(7):5167-5173.
15. Johansen J.S., Drivsholm L., Price P.A., Christensen I.J. High serum YKL-40 level in patients with small cell lung cancer is related to early death. Lung Cancer 2004, 46(3):333-340.
16. Otsuka K., Matsumoto H., Niimi A., Muro S., Ito I., Takeda T., Terada K., Yamaguchi M., Matsuoka H., Jinnai M., Oguma T., Nakaji H., Inoue H., Tajiri T., Iwata T., Chin K., Mishima M. Sputum YKL-40 levels and pathopsysiology of asthma and chronic obstructive pulmonary disease. Respiration 2012, 83(6):507-519.
17. Matsuura H., Hartl D., Kang M.J., Dela Cruz C.S., Koller B., Chupp G.L., Homer R.J., Zhou Y., Cho W.K., Elias J.A., Lee C.G. Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema. Am. J. Respir. Cell Mol. Biol. 2011, 44(6):777-786.
18. Park J.A., Tschumperlin D.J. Chronic intermittent mechanical stress increases MUC5AC protein expression. Am. J. Respir. Cell Mol. Biol. 2009, 41(4):459-466.
19. Hong J.H., Hong J.Y., Park B., Lee S.I., Seo J.T., Kim K.E., Sohn M.H., Shin D.M. Chitinase activates protease-activated receptor-2 in human airway epithelial cells. Am. J. Respir. Cell Mol. Biol. 2008, 39(5):530-535.
20. Bara I., Ozier A., Girodet P.O., Cattiaux J., Kolbeck R R., Coyle A., Tunon de Lara J.M., Marthan R., Berger P. The YKL-40-increased bronchial smooth muscle cell proliferation and migration is PAR-2 dependant. Eur. Respir. J. 2011, 38(Suppl. 55):747.
21. Bara I., Ozier A., Girodet P.O., Carvalho G., Cattiaux J., Begueret H., Thumerel M., Ousova O., Kolbeck R., Coyle A.J., Woods J., Tunon de Lara J.M., Marthan R., Berger P. Role of YKL-40 in bronchial smooth muscle remodeling in asthma. Am. J. Respir. Crit. Care Med. 2012, 185(7):715-722.
22. Elias J.A., Homer R.J., Hamid Q., Lee C.G. Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma. J. Allergy Clin. Immunol. 2005, 116(3):497-500.
23. Specjalski K., Jassem E. YKL-40 protein is a marker of asthma. J. Asthma. 2011, 48(8):767-772.
24. Chupp G.L., Lee C.G., Jarjour N., Shim T.M., Holm C.T., He S., Dziura J.D., Reed J., Coyle A.J., Kiener P., Cullen M., Grandsaigne M., Dombret M.C., Aubier M., Pretolani M., Elias J.A., Chitinase-like A Protein in the lung and circulation of patients with severe asthma. N. Engl. J. Med. 2007, 357(20):2016-2027.
25. Prakash M., Bodas M., Prakash D., Nawani N., Khetmalas M., Mandal A., Eriksson C. Diverse pathological implications of YKL-40: answers may lie in 'outside-in' signaling. Cell Signal. 2013, 25(7):1567-1573.
26. Page K., Strunk V.S., Hershenson M.B. Cockroach proteases increase IL-8 expression in human bronchial epithelial cells via activation of protease-activated receptor (PAR)-2 and extracellular-signal-regulated. J. Allergy Clin. Immunol 2003, 112(6):1112-1118.
27. Gershwin L.J. Effects of allergenic extracts on airway epithelium. Curr. Allergy Asthma Rep. 2007, 7(5):357-362.
28. Liu C., Li Q., Zhou X., Kolosov V.P., Perelman J.M. Human airway trypsin-like protease induces mucin5AC hypersecretion via a protease-activated receptor 2-mediated pathway in human airway epithelial cells. Arch. Biochem. Biophys. 2013, 535(2):234-240.
29. Francescone R.A., Scully S., Faibish M., Taylor S.L., Oh D., Moral L., Yan W., Bentley B., Shao R. Role of YKL-40 in the angiogenesis, radioresistance, and progression of glioblastoma. J. Biol. Chem. 2011, 286(17):15332-15343.
30. Li N., Li Q., Zhou X.D., Kolosov V.P., Perelman J.M. Chronic mechanical stress induces mucin 5AC expression in human bronchial epithelial cells through ERK dependent pathways. Mol. Biol. Rep. 2012, 39(2):1019-1028.
31. Beauvais D.M., Rapraeger A.C. Syndecan-1-mediated cell spreading requires signaling by alphavbeta3 integrins in human breast carcinoma cells. Exp. Cell Res. 2003, 286(2):219-232.
32. Shao R., Hamel K., Petersen L., Cao Q.J., Arenas R.B., Bigelow C., Bentley B., Yan W. YKL-40, a secreted glycoprotein, promotes tumor angiogenesis. Oncogene 2009, 28(50):4456-4468.
33. Johansen J.S., Bojesen S.E., Tybjaerg-Hansen A., Mylin A.K., Price P.A., Nordestgaard B.G. Plasma YKL-40 and total and disease-specific mortality in the general population. Clin. Chem. 2010, 56(10):1580-1591.