Rapamycin has suppressive and stimulatory effects on human plasmacytoid dendritic cell functions

Clinical and Experimental Immunology

Volumn 174, Issue 3, 2013, Pages 389-401

  Boor, P P C ^a   Metselaar, H J ^a   Mancham, S ^a   Van Der Laan, L J W ^a   Kwekkeboom, J ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

IFN ; mTOR; Toll like receptor

Indexed keywords

ALPHA INTERFERON; B7 ANTIGEN; CASPASE 3; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 3; INTERLEUKIN 6; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR FOXP3;

ADAPTIVE IMMUNITY; ANTIGEN EXPRESSION; ARTICLE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL FUNCTION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG EFFECT; HELPER CELL; HUMAN; HUMAN CELL; INNATE IMMUNITY; LYMPHOCYTE PROLIFERATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMORY T LYMPHOCYTE; PHENOTYPE; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; TH2 CELL; UPREGULATION;

IFN-Α; MTOR; TOLL-LIKE RECEPTOR;

ADAPTIVE IMMUNITY; ANTIGENS, CD; ANTIGENS, CD80; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; HUMANS; IMMUNITY, INNATE; IMMUNOLOGIC MEMORY; IMMUNOSUPPRESSIVE AGENTS; INTERFERON-ALPHA; INTERFERON-GAMMA; INTERLEUKIN-10; LYMPHOCYTE ACTIVATION; SIROLIMUS; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 9; TOR SERINE-THREONINE KINASES;

EID: 84886257842     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12191     Document Type: Article

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