Diclofenac removal in urine using strong-base anion exchange polymer resins

Water Research

Volumn 47, Issue 17, 2013, Pages 6432-6444

  Landry, Kelly A ^a   Boyer, Treavor H ^a  

^a University of Florida   (United States)

Author keywords

Electrostatic interactions; Ion exchange; Non steroidal anti inflammatory drugs; Pharmaceuticals; Sorption; Urine source separation; Van der Waals forces

Indexed keywords

BENZENE; COULOMB INTERACTIONS; DESORPTION; DRUG PRODUCTS; EFFLUENTS; ELECTROSTATICS; ION EXCHANGE RESINS; IONS; MIXTURES; POLYSTYRENES; SODIUM CHLORIDE; SORPTION; SOURCE SEPARATION; VAN DER WAALS FORCES;

ACIDIC PHARMACEUTICALS; ANION EXCHANGE RESINS; AQUEOUS NACL SOLUTIONS; ION EXCHANGE MECHANISMS; NON-STEROIDAL ANTI-INFLAMMATORY DRUGS; REGENERATION EFFICIENCY; STRONG BASE ANION EXCHANGES; WASTEWATER EFFLUENTS;

ION EXCHANGE;

ACRYLIC ACID RESIN; BENZENE; CARBOXYLIC ACID; CHLORIDE; CITRIC ACID; DICLOFENAC; KETOPROFEN; METHANOL; PHOSPHATE; POLYSTYRENE; QUATERNARY AMMONIUM DERIVATIVE; SODIUM CHLORIDE; WATER;

AQUEOUS SOLUTION; CONCENTRATION (COMPOSITION); DESORPTION; DRUG; EFFLUENT; ION EXCHANGE; MACROPORE; METHANOL; POLLUTANT REMOVAL; POLYMER; REGENERATION; RESIN; SODIUM CHLORIDE; URINE; WASTEWATER;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DESORPTION; DRUG EXCRETION; HUMAN; ION EXCHANGE; PRIORITY JOURNAL; STATIC ELECTRICITY; URINARY EXCRETION;

ELECTROSTATIC INTERACTIONS; ION-EXCHANGE; NON-STEROIDAL ANTI-INFLAMMATORY DRUGS; PHARMACEUTICALS; SORPTION; URINE SOURCE SEPARATION; VAN DER WAALS FORCES;

ANION EXCHANGE RESINS; CITRATES; DICLOFENAC; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; PHOSPHATES; POLYMERS; SPECTROPHOTOMETRY, ULTRAVIOLET; STATIC ELECTRICITY; TIME FACTORS;

EID: 84886237664     PISSN: 00431354     EISSN: 18792448     Source Type: Journal    
DOI: 10.1016/j.watres.2013.08.015     Document Type: Article

References (62)

1. Anand V., Kandarapu R., Garg S. Ion-exchange resins: carrying drug delivery forward. Drug Discov. Today 2001, 6(17):905-914.
2. Bäuerlein P.S., ter Laak T.L., Hofman-Caris R.C.H.M., de Voogt P., Droge S.T.J. Removal of charged micropollutants from water by ion-exchange polymers - effects of competing electrolytes. Water Res. 2012, 46(16):5009-5018.
3. Beltran-Heredia J., Palo P., Sanchez-Martin J., Dominguez J.R., Gonzalez T. Natural adsorbents derived from tannin extracts for pharmaceutical removal in water. Ind. Eng. Chem. Res. 2012, 51(1):50-57.
4. Blaney L.M., Cinar S., SenGupta A.K. Hybrid anion exchanger for trace phosphate removal from water and wastewater. Water Res. 2007, 41(7):1603-1613.
5. Boyer T.H., Singer P.C., Aiken G.R. Removal of dissolved organic matter by anion exchange: effect of dissolved organic matter properties. Environ. Sci. Technol. 2008, 42(19):7431-7437.
6. Boyer T.H., Taylor K., Reed A., Smith D. Ion-exchange softening of human urine to control precipitation. Environ. Prog. Sustain. Energy 2013, Accepted 17 June 2013, in press.
7. Bui T.X., Choi H. Adsorptive removal of selected pharmaceuticals by mesoporous silica SBA-15. J. Hazard. Mater. 2009, 168(2-3):602-608.
8. Clifford D., Weber W.J. The determinants of divalent/monovalent selectivity in anion exchangers. React. Polym. 1983, 1:77-89.
9. Comerton A.M., Andrews R.C., Bagley D.M., Hao C. The rejection of endocrine disrupting and pharmaceutically active compounds by NF and RO membranes as a function of compound and water matrix properties. J. Membr. Sci. 2008, 313(1-2):323-335.
10. Crittenden J.C., Trussell R.R., Hand D.W., Howe K.J., Tchobanoglous G. MWH's Water Treatment: Principles and Design 2012, John Wiley & Sons, Hoboken, N.J.
11. Dai C.-M., Geissen S.-U., Zhang Y.-l., Zhang Y.-j., Zhou X.-f. Selective removal of diclofenac from contaminated water using molecularly imprinted polymer microspheres. Environ. Poll. 2011, 159(6):1660-1666.
12. Deng S., Yu Q., Huang J., Yu G. Removal of perfluorooctane sulfonate from wastewater by anion exchange resins: effects of resin properties and solution chemistry. Water Res. 2010, 44(18):5188-5195.
13. Dodd M.C., Zuleeg S., Gunten U.v., Pronk W. Ozonation of source-separated urine for resource recovery and waste minimization: process modeling, reaction chemistry, and operational considerations. Environ. Sci. Technol. 2008, 42(24):9329-9337.
14. Dominguez J., Gonzalez T., Palo P., Cuerda-Correa E. Removal of common pharmaceuticals present in surface waters by Amberlite XAD-7 acrylic-ester-resin: Influence of pH and presence of other drugs. Desalination 2011, 269(1-3):231-238.
15. Standard Methods for the Examination of Water and Wastewater 2005, APHA, AWWA, WEF. A.D. Eaton, L.S. Clesceri, E.W. Rice, A.E. Greenberg (Eds.).
16. Epocrates Diclofenac Sodium 2013, Retreived 27.06.2013, from:. https://online.epocrates.com/u/107194/diclofenac+sodium/Pharmacology.
17. Escher B.I., Pronk W., Suter M.J.F., Maurer M. Monitoring the removal efficiency of pharmaceuticals and hormones in different treatment processes of source-separated urine with bioassays. Environ. Sci. Technol. 2006, 40(16):5095-5101.
18. Ferrando-Climent L., Collado N., Buttiglieri G., Gros M., Rodriguez-Roda I., Rodriguez-Mozaz S., Barceló D. Comprehensive study of ibuprofen and its metabolites in activated sludge batch experiments and aquatic environment. Sci. Total Environ. 2012, 438(0):404-413.
19. Gu B., Ku Y.-K., Jardine P.M. Sorption and binary exchange of nitrate, sulfate, and uranium on an anion-exchange resin. Environ. Sci. Technol. 2004, 38(11):3184-3188.
20. Gustafson R.L., Lirio J.A. Adsorption of organic ions by anion exchange resins. Ind. Eng. Chem. Prod. Res. Dev. 1968, 7(2):116-120.
21. Gustafsson J.P. Visual MINTEQ, Version 3.0 2011.
22. Hu H., Wang X., Li S., Huang J., Deng S. Bisphenol-A modified hyper-cross-linked polystyrene resin for salicylic acid removal from aqueous solution: adsorption equilibrium, kinetics and breakthrough studies. J. Colloid Interface Sci. 2012, 372(1):108-112.
23. Huang J., Jin X., Mao J., Yuan B., Deng R., Deng S. Synthesis, characterization and adsorption properties of diethylenetriamine-modified hypercrosslinked resins for efficient removal of salicylic acid from aqueous solution. J. Hazard. Mater. 2012, 217-218(0):406-415.
24. Indarawis K., Boyer T.H. Alkaline earth metal cation exchange: effect of mobile counterion and dissolved organic matter. Environ. Sci. Technol. 2012, 46(8):4591-4598.
25. Johir M., George J., Vigneswaran S., Kandasamy J., Grasmick A. Removal and recovery of nutrients by ion exchange from high rate membrane bio-reactor (MBR) effluent. Desalination 2011, 275(1-3):197-202.
26. Joss A., Keller E., Alder A., Gobel A., McArdell C., Ternes T., Siegrist H. Removal of pharmaceuticals and fragrances in biological wastewater treatment. Water Res. 2005, 39(14):3139-3152.
27. Kirchmann H., Pettersson S. Human urine - chemical composition and fertilizer use efficiency. Fertil. Res. 1995, 40(2):149-154.
28. Krajewska B. Ureases I. Functional, catalytic and kinetic properties: a review. J. Mol. Catalysis B: Enzym. 2009, 59(1-3):9-21.
29. Kuehl G., Lampe J., Potter J., Bigler J. Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes. Drug Metab. Dispos. 2005, 33(7):1027-1035.
30. Lamichhane K., Babcock R. An economic appraisal of using source separation of human urine to contain and treat endocrine disrupters in the USA. J. Environ. Monit. 2012, 14(10):2557-2565.
31. Larsen T., Gujer W. Separate management of anthropogenic nutrient solutions (human urine). Water Sci. Technol. 1996, 34(3-4):87-94.
32. Li P., Sengupta A.K. Genesis of selectivity and reversibility for sorption of synthetic aromatic anions onto polymeric sorbents. Environ. Sci. Technol. 1998, 32(23):3756-3766.
33. Li P., Sengupta A.K. Intraparticle diffusion during selective sorption of trace contaminants: the effect of gel versus macroporous morphology. Environ. Sci. Technol. 2000, 34(24):5193-5200.
34. Li P., SenGupta A.K. Sorption of hydrophobic ionizable organic compounds (HIOCs) onto polymeric ion exchangers. React. Funct. Polym. 2004, 60:27-39.
35. Lienert J., Buerki T., Escher B.I. Reducing micropollutants with source control: substance flow analysis of 212 pharmaceuticals in faeces and urine. Water Sci. Technol. 2007, 56(5):87-96.
36. Lienert J., Gudel K., Escher B.I. Screening method for ecotoxicological hazard assessment of 42 pharmaceuticals considering human metabolism and excretory routes. Environ. Sci. Technol. 2007, 41(12):4471-4478.
37. Maitani Y., Kugo M., Nakagaki M., Nagai T. Ionic size and behavior of diclofenac salts in water and ethanol/water mixtures by conductivity at 25 degrees C. J. Pharmaceut. Sci. 1993, 82(12):1245-1249.
38. Meloun M., Bordovska S., Galla L. The thermodynamic dissociation constants of four non-steroidal anti-inflammatory drugs by the least-squares nonlinear regression of multiwavelength spectrophotometric pH-titration data. J. Pharmaceut. Biomed. Anal. 2007, 45(4):552-564.
39. Mobley H.L., Hausinger R.P. Microbial ureases: significance, regulation, and molecular characterization. Microbiol. Rev. 1989, 53(1):85-108.
40. Pronk W., Palmquist H., Biebow M., Boller M. Nanofiltration for the separation of pharmaceuticals from nutrients in source-separated urine. Water Res. 2006, 40(7):1405-1412.
41. Reungoat J., Macova M., Escher B.I., Carswell S., Mueller J.F., Keller J. Removal of micropollutants and reduction of biological activity in a full scale reclamation plant using ozonation and activated carbon filtration. Water Res. 2010, 44(2):625-637.
42. Ronteltap M., Maurer M., Gujer W. The behaviour of pharmaceuticals and heavy metals during struvite precipitation in urine. Water Res. 2007, 41(9):1859-1868.
43. Ronteltap M., Maurer M., Gujer W. Struvite precipitation thermodynamics in source-separated urine. Water Res. 2007, 41(5):977-984.
44. Rossner A., Snyder S.A., Knappe D.R.U. Removal of emerging contaminants of concern by alternative adsorbents. Water Res. 2009, 43(15):3787-3796.
45. Salgado R., Marques R., Noronha J.P., Carvalho G., Oehmen A., Reis M.A.M. Assessing the removal of pharmaceuticals and personal care products in a full-scale activated sludge plant. Environ. Sci. Poll. Res. 2012, 19(5):1818-1827.
46. Samatya S., Kabay N., Yuksel U., Arda M., Yuksel M. Removal of nitrate from aqueous solution by nitrate selective ion exchange resins. React. Funct. Polym. 2006, 66(11):1206-1214.
47. Saude E.J., Sykes B.D. Urine stability for metabolomic studies: effects of preparation and storage. Metabolomics 2007, 3(1):19-27.
48. Sawchuk R., Maloney J., Cartier L., Rackley R., Chan K.H., Lau H.L. Analysis of diclofenac and four of its metabolites in human urine by HPLC. Pharmaceut. Res. 1995, 12(5):756-762.
49. Schwarzenbach R.P., Gschwend P.M., Imboden D.M. Environmental Organic Chemistry 2003, John Wiley & Sons.
50. Sena M.M., Chaudhry Z.F., Collins C.H., Poppi R.J. Direct determination of diclofenac in pharmaceutical formulations containing B vitamins by using UV spectrophotometry and partial least squares regression. J. Pharmaceut. Biomed. Anal. 2004, 36(4):743-749.
51. Sheng J.J., Kasim N.A., Chandrasekharan R., Amidon G.L. Solubilization and dissolution of insoluble weak acid, ketoprofen: effects of pH combined with surfactant. Eur. J. Pharmaceut. Sci. 2006, 29(3-4):306-314.
52. Todd P., Sorkin E. Diclofenac sodium. Drugs 1998, 35(3):244-285.
53. Turku I., Sainio T., Paatero E. Thermodynamics of tetracycline adsorption on silica. Environ. Chem. Lett. 2007, 5(4):225-228.
54. Udert K., Larsen T., Biebow M., Gujer W. Urea hydrolysis and precipitation dynamics in a urine-collecting system. Water Res. 2003, 37(11):2571-2582.
55. Udert K.M., Larsen T.A., Gujer W. Estimating the precipitation potential in urine-collecting systems. Water Res. 2003, 37(11):2667-2677.
56. Udert K.M., Larsen T.A., Gujer W. Fate of major compounds in source-separated urine. Water Sci. Technol. 2006, 54(11-12):413-420.
57. Weaver L.E., Carta G. Protein adsorption on cation exchangers: comparison of macroporous and gel-composite mdeia. Biotechnol. Prog. 1996, 12:342-355.
58. Wilsenach J.A., Schuurbiers C.A.H., van Loosdrecht M.C.M. Phosphate and potassium recovery from source separated urine through struvite precipitation. Water Res. 2007, 41(2):458-466.
59. Winker M., Faika D., Gulyas H., Otterpohl R. A comparison of human pharmaceutical concentrations in raw municipal wastewater and yellowwater. Sci. Total Environ. 2008, 399(1-3):96-104.
60. Winker M., Tettenborn F., Faika D., Gulyas H., Otterpohl R. Comparison of analytical and theoretical pharmaceutical concentrations in human urine in Germany. Water Res. 2008, 42(14):3633-3640.
61. Xiao F., Davidsavor K.J., Park S., Nakayama M., Phillips B.R. Batch and column study: sorption of perfluorinated surfactants from water and cosolvent systems by Amberlite XAD resins. J. Colloid Interface Sci. 2012, 368(1):505-511.
62. Zhang Y., Geissen S., Gal C. Carbamazepine and diclofenac: removal in wastewater treatment plants and occurrence in water bodies. Chemosphere 2008, 73(8):1151-1161.