Monitoring the removal efficiency of pharmaceuticals and hormones in different treatment processes of source-separated urine with bioassays

Environmental Science and Technology

Volumn 40, Issue 16, 2006, Pages 5095-5101

  Escher, Beate I ^a   Pronk, Wouter ^a   Suter, Marc J F ^a   Maurer, Max ^a  

^a SWISS FEDERAL INSTITUTE OF AQUATIC SCIENCE AND TECHNOLOGY   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTRANSFORMATION; ECOTOXICOLOGICAL POTENTIAL; REMOVAL EFFICIENCY; STRUVITE;

CONDITION MONITORING; DRUG PRODUCTS; HORMONES; OZONIZATION; PHASE SEPARATION; TOXICITY;

WASTEWATER TREATMENT;

CHLOROPHYLL; FERTILIZER; HORMONE;

CONDITION MONITORING; DRUG PRODUCTS; HORMONES; OZONIZATION; PHASE SEPARATION; TOXICITY; WASTEWATER TREATMENT;

BIOASSAY; DRUG; HORMONE; NUTRIENT; PHYTOTOXICITY; POLLUTANT REMOVAL; RECYCLING; URINE; WASTE TREATMENT;

ARTICLE; BATCH REACTOR; BIOASSAY; BIOTRANSFORMATION; ENVIRONMENTAL MONITORING; NANOFILTRATION; OZONATION; PHASE SEPARATION; PHYTOTOXICITY; TECHNIQUE; URINE; WASTE COMPONENT REMOVAL; WASTE WATER RECYCLING; WASTE WATER TREATMENT PLANT; WATER POLLUTION;

BIOLOGICAL ASSAY; CHLOROPHYLL; DIALYSIS; ELECTROCHEMISTRY; ENVIRONMENTAL MONITORING; ESTROGENS; FERTILIZERS; FILTRATION; HORMONES; HUMANS; PHARMACEUTICAL PREPARATIONS; URINE; WASTE DISPOSAL, FLUID; WATER POLLUTANTS, CHEMICAL;

ALGAE;

EID: 33747493100     PISSN: 0013936X     EISSN: None     Source Type: Journal    
DOI: 10.1021/es060598w     Document Type: Article

References (40)

1. Ternes, T. A. Occurrence of drugs in German sewage treatment plants and rivers. Chemosphere 1998, 32, 3245-3260.
2. Daughton, C.; Ternes, T. Pharmaceuticals and personal care products in the environment: agents of subtle change? Environ. Health Perspect. 1999, 107 Supp. 6, 907-937.
3. Kolpin, D. W.; Furlong, E. T.; Meyer, M. T.; Thurman, E. M.; Zaugg, S. D. Pharmaceuticals, hormones, and other organic contaminants in U.S. streams, 1999-2000: a national reconnaissance. Environ. Sci. Technol. 2002, 36, 1201-1211.
4. Kirchmann, H.; Pettersson, S. Human urine-chemical composition and fertilizer use efficiency. Fertilizer Res. 1995, 40, 149-154.
5. Larsen, T. A.; Gujer, W. Separate management of anthropogenic nutrient solutions (human urine). Water Sci. Technol. 1996, 34, 87-94.
6. Larsen, T. A.; Lienert, J.; Joss, A.; Siegrist, H. How to avoid pharmaceuticals in the aquatic environment. J. Biotechnol. 2004, 113, 295-304.
7. Larsen, T. A.; Peters, I.; Alder, A.; Eggen, R. I. L.; Maurer, M.; Muncke, J. Re-engineering the toilet for sustainable waste water management. Environ. Sci. Technol. 2001, 35, 192A-197A.
8. Wilsenach, J. A.; Van Loosdrecht, M. C. M. Effects of separate urine collection on advanced nutrient removal processes. Environ. Sci. Technol. 2004, 38, 1208-1215.
9. Heinonen-Tanski, H.; van Wijk-Sijbesma, C. Human excreta for plant production. Bioresour. Technol. 2005, 96, 403-411.
10. Maurer, M.; Pronk, W.; Larsen, T. A. Treatment processes for source separated urine. Water Res., in press.
11. Bridger, G. L.; Salutsky, M. L.; Starostka, R. W. Metal ammonium phosphates as fertilisers. Abstracts of the 140th Meeting of the American Chemical Society; Chicago: Illinois, 1961.
12. Johnston, A. E.; Richards, I. R. Effectiveness of different precipitated phosphates as phosphorus sources for plants. Soil Use Manage. 2003, 19, 45-49.
13. Huber, M. M.; Canonica, S.; Park, G. Y.; Von Gunten, U. Oxidation of pharmaceuticals during ozonation and advanced oxidation processes. Environ. Sci. Technol. 2003, 37, 1016-1024.
14. Pronk, W.; Dodd, M.; Zuleeg, S.; Escher, B. I.; von Gunten, U. The ozonation of micropollutants in source-separated urine., in preparation.
15. Sumpter, J. P., Endocrine disruption and feminization in fish. Toxicology 2002, 178, 39-40.
16. Länge, R.; Dietrich, D., Environmental risk assessment of pharmaceutical drug substances-conceptual considerations. Toxicol. Lett. 2002, 131, 97-104.
17. Daughton, C. G. PPCP's in the Environment: future research-beginning with the end always in mind. In Pharmaceuticals in the Environment; Kümmerer, K., Ed.; Springer: New York, 2004; pp 463-495.
18. Sanderson, H.; Johnson, D. J.; Reitsma, T.; Brain, R. A.; Wilson, C. A.; Solomon, K. R. Ranking and prioritization of environmental risks of pharmaceuticals in surface waters. Regul. Toxicol. Pharmacol. 2004, 39, 158-183.
19. Escher, B. I.; Bramaz, N.; Eggen, R. I. L.; Richter, M. In-vitro assessment of modes of toxic action of pharmaceuticals in aquatic life. Environ. Sci. Technol. 2005, 39, 3090-3100.
20. Escher, B. I.; Bramaz, N.; Maurer, M.; Richter, M.; Sutter, D.; von Känel, C.; Zschokke, M., Screening test battery for pharmaceuticals in urine and wastewater. Environ. Toxicol. Chem. 2005, 24, 750-758.
21. Schreiber, U.; Müller, J.; Haugg, A.; Gademann, R. New type of dual-channel PAM chlorophyll fluorometer for highly sensitive water toxicity biotests. Photosynth. Res. 2003, 74, 317-330.
22. Routledge, E.; Sumpter, J. Estrogenic activity of surfactants and some of their degradation products assessed during a recombinant yeast estrogen screen. Environ. Toxicol. Chem. 1996, 15, 241-248.
23. Oda, J.; Nakamura, S. I.; Oki, I.; Kato, T.; Shinagawa, H. Evaluation of the new system (umu-test) for the detection of environmental mutagens and carcinogens. Mutat. Res. 1985, 147, 219-229.
24. Udert, K. M.; Fux, C.; Münster, M.; A. L. T.; Siegrist, H.; Guyer, W. Nitrification and autotrophic denitrification of source-separated urine. Water Sci. Technol. 2003, 48, 119-130.
25. Pronk, W.; Biebow, M.; Boller, M. Electrodialysis for recovering by salts from a urine solution containing micropollutants Environ. Sci. Technol. 2006, 40, 2414-2420.
26. Pronk, W.; H, P.; Biebow, M.; Boller, M. Nanofiltration for the separation of pharmaceuticals from nutrients in source-separated urine. Water Res. 2006, 40, 1405-1412.
27. Huber, M. M.; Göbel, A.; Joss, A.; Hermann, N.; Löffler, D.; McArdell, C. S.; Ried, A.; Siegrist, H.; Ternes, T. A.; von Gunten, U., Oxidation of pharmaceuticals during ozonation of municipal wastewater effluents: A pilot study. Environ. Sci. Technol. 2005, 39, 4290-4299.
28. Huber, M. M.; Ternes, T. A.; von Gunten, U. Removal of estrogenic activity and formation of oxidation products during ozonation of 17 alpha-ethinylestradiol. Environ. Sci. Technol. 2004, 38, 5177-5186.
29. Vermeirssen, E.; Körner, O.; Schönenberger, R.; Suter, M. J.-F.; Burckhardt-Holm, P., Characterisation of environmental estrogens in river water using a three pronged approach: active and passive water sampling and the analysis of accumulated estrogens in the bile of caged fish. Environ. Sci. Technol. 2005, 39, 8191-8198.
30. Niederer, C.; Behra, R.; Harder, A.; Schwarzenbach, R. P.; Escher, B. I., Mechanistic approaches for evaluating the toxicity of reactive organochlorines and epoxides in green algae. Environ. Toxicol. Chem. 2004, 23, 697-704.
31. Rutishauser, B. V.; Pesonen, M.; Escher, B. I.; Ackermann, G. E.; Aerni, H.-R.; Suter, M. J.-F.; Eggen, R. I. L. Comparative analysis of estrogenic activity in sewage treatment plant effluents involving three in vitro assays and chemical analysis of steroids. Environ. Toxicol. Chem. 2004, 23, 857-864.
32. International Standard Organisation Water quality - Determination of the genotoxicity of water and waste water using the umu-test, EN ISO 13829 2000 and 38415-3 1996; International Standard Organisation: Geneva.
33. Ciba Geigy Harn- Physikalisch-chemische Daten. In Wissenschaftliche Tabellen Geigy- Körperflüssigkeiten; Ciba Geigy AG: Basel, Switzerland, 1977; pp 51-96.
34. Altenburger, R.; Walter, H.; Grote, M. What contributes to the combined effect of a complex mixture? Environ. Sci. Technol. 2004, 38, 6353-6362.
35. Junghans, M.; Backhaus, T.; Faust, M.; Scholze, M.; Grimme, L. H. Application and validation of approaches for the predictive hazard assessment of realistic pesticide mixtures. Aquat. Toxicol. 2006, 76, 93-110.
36. Nghiem, L. D.; Schäfer, A. I.; Elimelech, M. Pharmaceutical retention mechanisms by nanofiltration membranes. Environ. Sci. Technol. 2005, 39, 7698-7705.
37. Sutter, D.; Zschokke, M. Abbau von Pharmaka in Urin-Bioreaktoren, Swiss Federal Institute of Technology, Diploma Thesis, ETH, Zürich, Switzerland, 2003.
38. Ronteltap, M.; Maurer, M. Fate of micropollutants during struvite precipitation in source separated urine; Internal Report, Eawag, Switzerland, 2006.
39. Escher, B. I.; Bramaz, N.; Richter, M.; Lienert, J. Comparative ecotoxicological hazard assessment of beta-blockers and their human metabolites. Environ. Sci. Technol. 2006, in press.
40. Dillon, D.; Combes, R.; McConville, M.; Zeiger, E. Ozone is mutagenic in Salmonella. Environ. Mol. Mutagen. 1992, 19, 331-337.