Focal adhesion kinase mediates atrial fibrosis via the AKT/S6K signaling pathway in chronic atrial fibrillation patients with rheumatic mitral valve disease

International Journal of Cardiology

Volumn 168, Issue 4, 2013, Pages 3200-3207

  Zhang, Peide ^b   Wang, Wei ^a   Wang, Xin ^b   Wang, Xu ^b   Song, Yunhu ^b   Zhang, Jing ^b   Zhao, Hui ^b  

^a FUWAI HOSPITAL   (China)

^b NONE

Author keywords

AKT S6K signaling; Atrial fibrosis; Chronic atrial fibrillation; Focal adhesion kinase; Rheumatic mitral valve disease

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; FOCAL ADHESION KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; S6 KINASE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HEART ATRIUM APPENDAGE; HEART ATRIUM FIBRILLATION; HEART ATRIUM FIBROSIS; HEART MUSCLE FIBROSIS; HEART SURGERY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MITRAL VALVE DISEASE; MYOFIBROBLAST; NEWBORN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RHEUMATIC HEART DISEASE; SIGNAL TRANSDUCTION; SINUS RHYTHM; WESTERN BLOTTING;

AKT/S6K SIGNALING; ATRIAL FIBROSIS; CHRONIC ATRIAL FIBRILLATION; FOCAL ADHESION KINASE; RHEUMATIC MITRAL VALVE DISEASE;

ANIMALS; ANIMALS, NEWBORN; ATRIAL APPENDAGE; ATRIAL FIBRILLATION; CELLS, CULTURED; CHRONIC DISEASE; FEMALE; FIBROSIS; FOCAL ADHESION KINASE 1; HUMANS; MALE; MIDDLE AGED; MITRAL VALVE; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RHEUMATIC HEART DISEASE; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION;

EID: 84886234973     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2013.04.113     Document Type: Article

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