Advances in mechanisms of atrial fibrillation: Structural remodeling, high-frequency fractionated electrograms, and reentrant AF drivers

Journal of Interventional Cardiac Electrophysiology

Volumn 23, Issue 1, 2008, Pages 45-49

  Makati, Kevin J ^a   Alsheikh Ali, Alawi A ^a   Garlitski, Ann C ^a   Link, Mark S ^a   Homoud, Munther ^a   Weinstock, Jonathan ^a   Estes III, N A Mark ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Division of Cardiology   (United States)

Author keywords

Atrial fibrillation; Complex fractionated electrograms; Reentry; Remodeling

Indexed keywords

CONNEXIN 40; CONNEXIN 43; CONNEXIN 45;

BIOLOGICAL MODEL; CATHETER ABLATION; DISEASE PREDISPOSITION; ELECTROCARDIOGRAM; ELECTROPHYSIOLOGY; HEART ATRIUM; HEART ATRIUM CONDUCTION; HEART ATRIUM FIBRILLATION; HEART ATRIUM PACING; HEART MUSCLE; HEART MUSCLE FIBROSIS; HUMAN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REENTRY ARRHYTHMIA; REVIEW;

ATRIAL FIBRILLATION; BODY SURFACE POTENTIAL MAPPING; CATHETER ABLATION; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; HUMANS; TACHYCARDIA, RECIPROCATING; VENTRICULAR REMODELING;

EID: 53949116807     PISSN: 1383875X     EISSN: 15728595     Source Type: Journal    
DOI: 10.1007/s10840-008-9256-8     Document Type: Review

References (41)

1. V. Fuster L. E. Ryden D. S. Cannom H. J. Crijns A. B. Curtis K. A. Ellenbogen 2006 Guidelines for the management of patients with atrial fibrillation: A report of the American college of cardiology/American heart association task force on practice guidelines and the European society of cardiology committee for practice guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation): Developed in collaboration with the European heart rhythm association and the heart rhythm society Circulation 114 7 e257 354
2. J. Y. Le Heuzey O. Paziaud O. Piot M. A. Said X. Copie T. Lavergne 2004 Cost of care distribution in atrial fibrillation patients: The COCAF study American Heart Journal 147 1 121 126
3. D. M. Lloyd-Jones T. J. Wang E. P. Leip M. G. Larson D. Levy R. S. Vasan 2004 Lifetime risk for development of atrial fibrillation: The Framingham Heart Study Circulation 110 9 1042 1046
4. Th. W. Engelmann 1896 Über den Einfluss der Systole auf die Motorische Leitung in der Herzkammer, mit Bemerkungen zur Theorie Allorhythmischer Herzstörungen Pflügers Archiv European Journal of Physiology 62 12 543 566
5. T. Lewis F. H. W. D. Stroud 1920 Observations upon flutter and fibrillaqtion. II: The nature of auricular flutter Heart 7 191 245
6. G. K. Moe J. A. Abildskov 1959 Atrial fibrillation as a self-sustaining arrhythmia independent of focal discharge American Heart Journal 58 1 59 70
7. M. Allessie J. Ausma U. Schotten 2002 Electrical, contractile and structural remodeling during atrial fibrillation Cardiovascular Research 54 2 230 246
8. P. Jais M. Haissaguerre D. C. Shah S. Chouairi L. Gencel M. Hocini 1997 A focal source of atrial fibrillation treated by discrete radiofrequency ablation Circulation 95 3 572 576
9. O. Berenfeld A. V. Zaitsev S. F. Mironov A. M. Pertsov J. Jalife 2002 Frequency-dependent breakdown of wave propagation into fibrillatory conduction across the pectinate muscle network in the isolated sheep right atrium Circulation Research 90 11 1173 1180
10. R. Mandapati A. Skanes J. Chen O. Berenfeld J. Jalife 2000 Stable microreentrant sources as a mechanism of atrial fibrillation in the isolated sheep heart Circulation 101 2 194 199
11. K. Derakhchan D. Li M. Courtemanche B. Smith J. Brouillette P. L. Page 2001 Method for simultaneous epicardial and endocardial mapping of in vivo canine heart: Application to atrial conduction properties and arrhythmia mechanisms Journal of Cardiovascular Electrophysiology 12 5 548 555
12. D. Katritsis E. Iliodromitis N. Fragakis S. Adamopoulos D. Kremastinos 1996 Ablation therapy of type I atrial flutter may eradicate paroxysmal atrial fibrillation American Journal of Cardiology 78 3 345 347
13. W. Garrey 1914 The nature of fibrillation contraction of the heart; Its relation to tissue mass and form American Journal of Physiology 33 397 414
14. G. K. Moe W. C. Rheinboldt J. A. Abildskov 1964 A computer model of atrial fibrillation American Heart Journal 67 200 220
15. J. A. Abildskov 1994 Additions to the wavelet hypothesis of cardiac fibrillation Journal of Cardiovascular Electrophysiology 5 6 553 559
16. Allessie, M. A., Bonke, F. I. M. L. W., & Hollen, J. (1985). Experimental evaluation of Moe's multiple wavelet hypothesis of atrial fibrillation. In J. J. D. P. Zipes (Ed.), Cardiac electrophysiology of arrhythmias. New York: Grune & Stratton.
17. M. Haissaguerre P. Jais D. C. Shah A. Takahashi M. Hocini G. Quiniou 1998 Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins New England Journal of Medicine 339 10 659 666
18. R. Arora S. Verheule L. Scott A. Navarrete V. Katari E. Wilson 2003 Arrhythmogenic substrate of the pulmonary veins assessed by high-resolution optical mapping Circulation 107 13 1816 1821
19. K. Kumagai M. Ogawa H. Noguchi T. Yasuda H. Nakashima K. Saku 2004 Electrophysiologic properties of pulmonary veins assessed using a multielectrode basket catheter Journal of the American College of Cardiology 43 12 2281 2289
20. S. A. Chen M. H. Hsieh C. T. Tai C. F. Tsai V. S. Prakash W. C. Yu 1999 Initiation of atrial fibrillation by ectopic beats originating from the pulmonary veins: Electrophysiological characteristics, pharmacological responses, and effects of radiofrequency ablation Circulation 100 18 1879 1886
21. K. Nademanee J. McKenzie E. Kosar M. Schwab B. Sunsaneewitayakul T. Vasavakul 2004 A new approach for catheter ablation of atrial fibrillation: Mapping of the electrophysiologic substrate Journal of the American College of Cardiology 43 11 2044 2053
22. K. T. Konings J. L. Smeets O. C. Penn H. J. Wellens M. A. Allessie 1997 Configuration of unipolar atrial electrograms during electrically induced atrial fibrillation in humans Circulation 95 5 1231 1241
23. H. Oral A. Chugh E. Good A. Wimmer S. Dey N. Gadeela 2007 Radiofrequency catheter ablation of chronic atrial fibrillation guided by complex electrograms Circulation 115 20 2606 2612
24. D. Shah H. Sunthorn H. Burri P. Gentil-Baron E. Pruvot J. Schlaepfer 2006 Narrow, slow-conducting isthmus dependent left atrial reentry developing after ablation for atrial fibrillation: ECG characterization and elimination by focal RF ablation Journal of Cardiovascular Electrophysiology 17 5 508 515
25. O. Berenfeld R. Mandapati S. Dixit A. C. Skanes J. Chen M. Mansour 2000 Spatially distributed dominant excitation frequencies reveal hidden organization in atrial fibrillation in the Langendorff-perfused sheep heart Journal of Cardiovascular Electrophysiology 11 8 869 879
26. L. Yue J. Feng R. Gaspo G. R. Li Z. Wang S. Nattel 1997 Ionic remodeling underlying action potential changes in a canine model of atrial fibrillation Circulation Research 81 4 512 525
27. R. F. Bosch S. Nattel 2002 Cellular electrophysiology of atrial fibrillation Cardiovascular Research 54 2 259 269
28. D. M. Todd S. P. Fynn A. P. Walden W. J. Hobbs S. Arya C. J. Garratt 2004 Repetitive 4-week periods of atrial electrical remodeling promote stability of atrial fibrillation: Time course of a second factor involved in the self-perpetuation of atrial fibrillation Circulation 109 11 1434 1439
29. Z. Yang W. Shen J. N. Rottman J. P. Wikswo K. T. Murray 2005 Rapid stimulation causes electrical remodeling in cultured atrial myocytes Journal of Molecular and Cellular Cardiology 38 2 299 308
30. W. Dun N. Ozgen M. Hirose E. A. Sosunov E. P. Anyukhovsky M. R. Rosen 2007 Ionic mechanisms underlying region-specific remodeling of rabbit atrial action potentials caused by intermittent burst stimulation Heart Rhythm 4 4 499 507
31. E. Dupont Y. Ko S. Rothery S. R. Coppen M. Baghai M. Haw 2001 The gap-junctional protein connexin40 is elevated in patients susceptible to postoperative atrial fibrillation Circulation 103 6 842 849
32. P. Kanagaratnam A. Cherian R. D. Stanbridge B. Glenville N. J. Severs N. S. Peters 2004 Relationship between connexins and atrial activation during human atrial fibrillation Journal of Cardiovascular Electrophysiology 15 2 206 216
33. B. J. Brundel J. Ausma I. C. van Gelder J. J. Van der Want W. H. van Gilst H. J. Crijns 2002 Activation of proteolysis by calpains and structural changes in human paroxysmal and persistent atrial fibrillation Cardiovascular Research 54 2 380 389
34. K. Tanaka S. Zlochiver K. L. Vikstrom M. Yamazaki J. Moreno M. Klos 2007 The spatial distribution of fibrosis governs fibrillation wave dynamics in the posterior left atrium during heart failure Circulation Research 101 839 847
35. N. Hanna S. Cardin T. K. Leung S. Nattel 2004 Differences in atrial versus ventricular remodeling in dogs with ventricular tachypacing-induced congestive heart failure Cardiovascular Research 63 2 236 244
36. T. J. Cha J. R. Ehrlich L. Zhang Y. F. Shi J. C. Tardif T. K. Leung 2004 Dissociation between ionic remodeling and ability to sustain atrial fibrillation during recovery from experimental congestive heart failure Circulation 109 3 412 418
37. D. Li K. Shinagawa L. Pang T. K. Leung S. Cardin Z. Wang 2001 Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure Circulation 104 21 2608 2614
38. A. A. Alsheikh-Ali P. J. Wang W. Rand M. A. Konstam M. K. Homoud M. S. Link 2004 Enalapril treatment and hospitalization with atrial tachyarrhythmias in patients with left ventricular dysfunction American Heart Journal 147 6 1061 1065
39. E. Vermes J. C. Tardif M. G. Bourassa N. Racine S. Levesque M. White 2003 Enalapril decreases the incidence of atrial fibrillation in patients with left ventricular dysfunction: Insight from the Studies of Left Ventricular Dysfunction (SOLVD) trials Circulation 107 23 2926 2931
40. K. Wachtell M. Lehto E. Gerdts M. H. Olsen B. Hornestam B. Dahlof 2005 Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol: The Losartan Intervention for End Point Reduction in Hypertension (LIFE) study Journal of the American College of Cardiology 45 5 712 719
41. B. A. Schoonderwoerd J. Ausma H. J. Crijns D. J. Van Veldhuisen E. H. Blaauw I. C. Van Gelder 2004 Atrial ultrastructural changes during experimental atrial tachycardia depend on high ventricular rate Journal of Cardiovascular Electrophysiology 15 10 1167 1174