Cytotoxicity of polystyrene nanospheres internalization in mouse fibroblast cells

2008 2nd IEEE International Nanoelectronics Conference, INEC 2008

Volumn , Issue , 2008, Pages 1087-1092

  Jin, Cheng Yu ^a   Zhu, Bang Shang ^a   Lu, Qing Hua ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Cell cycle; Cell morphology; Cytotoxicity; Oxidative stress; Polystyrene nanospheres

Indexed keywords

CELL CULTURE; CELLS; CONCENTRATION (PROCESS); CYTOLOGY; CYTOTOXICITY; ELECTRONICS ENGINEERING; FIBROBLASTS; NANOELECTRONICS; NANOSPHERES; NANOSTRUCTURES; TECHNOLOGY;

CELL CYCLE; CELL MORPHOLOGY; ENVIRONMENTAL SAFETY; FIBROBLAST CELLS; GOVERNMENT REGULATORS; HUMAN HEALTH; LACTATE DEHYDROGENASE; NANO-MATERIALS; OXIDATIVE STRESS; POLYSTYRENE NANOSPHERES; SIZE EFFECTS;

NANOSTRUCTURED MATERIALS;

EID: 52649168402     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/INEC.2008.4585672     Document Type: Conference Paper

References (14)

1. T. Xia, M. Kovochich, J. Brant, M. Hotze, J. Sempf, T. Oberley et al. "Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm," Nano Lett., vol. 6 (8), pp. 1794-1807, 2006.
2. C.W. Lam, J.T. James, R. McCluskey, R.L. Hunter, "Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation," Toxicol. Sci., vol. 77, pp. 126-134, 2004.
3. K. Soto, K.M. Garza, L.E. Murr, "Cytotoxic effects of aggregated nanomaterials," Acta Biomater., vol. 3, pp. 351-358, 2007.
4. D.B. Warheit, T.R. Webb, K.L. Reed, S. Frerichs, C.M. Sayes, "Pulmonary toxicity study in rats with three forms of ultrafine-TiO2 particles: Differential responses related to surface properties," Toxicology, vol. 230, pp. 90-104, 2007.
5. H.W. Chen, S.F. Su, C.T. Chien, W.H. Lin, S.L. Yu, C.C. Chou et al., "Titanium dioxide nanoparticles induce emphysema-like lung injury in mice" The FASEB J., pp.E1732-E1741, 2006.
6. K.F. Soto, A. Carrasco, T.G. Powell, K.M. Garza, L.E. Murr, "Comparative in vitro cytotoxicity assessment of some manufactured nanoparticulate materials characterized by transmission electron microscopy," J. Nanopart. Res., vol. 7, pp. 145-169, 2005.
7. S. Ivankovic, S. Music, M. Gotic, N. Ljubesic, "Cytotoxicity of nanosize V205 particles to selected fibroblast and tumor cells," Toxicol. in Vitro, vol. 20, pp. 286-294, 2006.
8. K.F. Soto, A. Carrasco, T.G. Powell, L.E. Murr, K.M. Garza, "Biological effects of nanoparticulate materials," Mater. Sci. Eng. C-Bio., vol. S. 26, pp. 1421-1427, 2006.
9. J. Hamoir, A. Nemmar, D. Halloy, D. Wirth, G. Vincke, A. Vanderplasschen, B. Nemery, P. Gustin, "Effect of polystyrene particles on lung microvascular permeability in isolated perfused rabbit lungs: role of size and surface properties," Toxicol. Appl. Pharmacol, vol. 190, pp. 278-285, 2003.
10. C. Monteiller, L. Tran, W. MacNee, S. Faux, A. Jones, B. Miller and K. Donaldson, "The pro-inflammatory effects of low - toxicity low -solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area," Occup. Environ. Med., vol. 64 (9), pp. 609-615, 2007.
11. W. Zauner, N.A. Farrow, A.M.R. Haines, "In vitro uptake of polystyrene microspheres: effect of particle size, cell line and cell density," J. Controlled Release, vol. 71, pp. 39-51, 2001.
12. A. Nel, T. Xia, L. Madler, N. Li, "Toxic potential of materials at the nanolevel," Science, vol. 311, pp. 622-627, 2006.
13. L. Foghsgaard, D. Wissing, D. Mauch, U. Lademann et al, "Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor," J. Cell Biol., vol. 153, pp. 999-1009, 2001.
14. P. Boya, K. Andreau et al., "Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion," J. Exp. Med., vol. 197, pp. 1323-1334, 2003.