High-fat-cholesterol diet mainly induced necrosis in fibrotic steatohepatitis rat by suppressing caspase activity

Life Sciences

Volumn 93, Issue 18-19, 2013, Pages 673-680

  Yetti, Husna ^a   Naito, Hisao ^a   Jia, Xiaofang ^a   Shindo, Moritaka ^a   Taki, Hitoshi ^a   Tamada, Hazuki ^a,b   Kitamori, Kazuya ^a,b   Hayashi, Yumi ^a   Ikeda, Katsumi ^c   Yamori, Yukio ^c   Nakajima, Tamie ^a,d  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KINJO GAKUIN UNIVERSITY   (Japan)

^c MUKOGAWA WOMEN'S UNIVERSITY   (Japan)

^d CHUBU UNIVERSITY   (Japan)

Author keywords

Apoptosis; Caspase activity; Hepatic necrosis; High fat cholesterol diet; K18Asp396

Indexed keywords

CASPASE; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CYTOCHROME C; CYTOKERATIN 18; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; LIVER FIBROSIS; LIVER NECROSIS; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; STROKE PRONE SPONTANEOUSLY HYPERTENSIVE RAT;

APOPTOSIS; CASPASE ACTIVITY; HEPATIC NECROSIS; HIGH-FAT-CHOLESTEROL DIET; K18ASP396;

ANIMALS; CASPASE INHIBITORS; CASPASES; CHOLESTEROL, DIETARY; DIET, HIGH-FAT; ENZYME ACTIVATION; FATTY LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; NECROSIS; RATS; RATS, INBRED SHR;

ANIMALIA; RATTUS;

EID: 84886090990     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.09.013     Document Type: Article

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