Controllable production of low molecular weight heparins by combinations of heparinase I/II/III

Carbohydrate Polymers

Volumn 101, Issue 1, 2014, Pages 484-492

  Wu, Jingjun ^a   Zhang, Chong ^a   Mei, Xiang ^a   Li, Ye ^a,b   Xing, Xin Hui ^a  

^a TSINGHUA UNIVERSITY   (China)

^b Beijing Vocational College of Electronic Science and Technology   (China)

Author keywords

Enzymatic depolymerization; Heparin; Heparinases; Low molecular weight heparin

Indexed keywords

ANTICOAGULANT ACTIVITIES; ENZYMATIC DEPOLYMERIZATION; HEPARIN; HEPARINASES; HIGH SELECTIVITY; LOW MOLECULAR WEIGHT HEPARIN (LMWHS); LOW-MOLECULAR WEIGHT HEPARINS; MILD REACTION CONDITIONS;

MOLECULAR WEIGHT;

POLYSACCHARIDES;

ANTITHROMBIN III; HEPARIN; HEPARIN LYASE; HEPARINASE II; HEPARITINSULFATE LYASE; LOW MOLECULAR WEIGHT HEPARIN; MALTOSE BINDING PROTEIN; POLYSACCHARIDE LYASE; RI;

N-Α-BENZYLOXYCARBONYL-D-ARGINYL-L-GLYCYL-L-ARGININE-P-NITROANILINE-DIHYDROCHLORIDE; 2-O-SULFO-Α-L-IDURONIC ACID; 3,6-DI-O-SULFO-N-SULFO-Α-D-GLUCOSAMINE; 6-O-SULFO-N-SULFO-Α-D-GLUCOSAMINE; 6-O-SULFO-Α-D-N-ACETYLGLUCOSAMINE; ARTICLE; AT-III; CHEMISTRY; DEGREE OF POLYMERIZATION; DP; ENZYMATIC DEPOLYMERIZATION; GEL PERMEATION CHROMATOGRAPHY; GLCA; GLCNAC; GLCNAC6S; GLCNS; GLCNS3S6S; GLCNS6S; GPC; H-D-PHENYLALANYL-L-PIPECOLYL-ARGININE-P-NITROANILINE DIHYDROCHLORIDE; HEPARIN INDUCED THROMBOCYTOPENIA; HEPARINASE I; HEPARINASE III; HEPARINASES; HEPI; HEPII; HEPIII; HIGH PERFORMANCE CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIT; IDOA; IDOA2S; IPTG; ISOPROPYL-Β-D-1-THIOGALACTOPYRANOSIDE; LC-MS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; LMWHS; LOW MOLECULAR WEIGHT HEPARINS; M(N); M(W); MBP; METABOLISM; MOLECULAR WEIGHT; N-SULFO-Α-D-GLUCOSAMINE; NUMBER AVERAGE MOLECULAR WEIGHT; PA; PHOTODIODE ARRAY; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERIZATION; REFRACTION INDEX; S-2238; S-2765; ULTRAVIOLET RADIATION; WEIGHT AVERAGE MOLECULAR WEIGHT; Α-D-N-ACETYLGLUCOSAMINE; Α-L-IDURONIC ACID; Β-D-GLUCURONIC ACID;

N-Α-BENZYLOXYCARBONYL-D-ARGINYL-L-GLYCYL-L-ARGININE-P-NITROANILINE-DIHYDROCHLORIDE; 2-O-SULFO-Α-L-IDURONIC ACID; 3,6-DI-O-SULFO-N-SULFO-Α-D-GLUCOSAMINE; 6-O-SULFO-N-SULFO-Α-D-GLUCOSAMINE; 6-O-SULFO-Α-D-N-ACETYLGLUCOSAMINE; ANTITHROMBIN III; AT-III; DEGREE OF POLYMERIZATION; DP; ENZYMATIC DEPOLYMERIZATION; GEL PERMEATION CHROMATOGRAPHY; GLCA; GLCNAC; GLCNAC6S; GLCNS; GLCNS3S6S; GLCNS6S; GPC; H-D-PHENYLALANYL-L-PIPECOLYL-ARGININE-P-NITROANILINE DIHYDROCHLORIDE; HEPARIN; HEPARIN-INDUCED THROMBOCYTOPENIA; HEPARINASE I; HEPARINASE II; HEPARINASE III; HEPARINASES; HEPI; HEPII; HEPIII; HIGH PERFORMANCE CHROMATOGRAPHY; HIT; HPLC; IDOA; IDOA2S; IPTG; ISOPROPYL-Β-D-1-THIOGALACTOPYRANOSIDE; LC-MS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; LMWHS; LOW MOLECULAR WEIGHT HEPARIN; LOW MOLECULAR WEIGHT HEPARINS; M(N); M(W); MALTOSE BINDING PROTEIN; MBP; N-SULFO-Α-D-GLUCOSAMINE; NUMBER AVERAGE MOLECULAR WEIGHT; PA; PAGE; PHOTODIODE ARRAY; POLYACRYLAMIDE GEL ELECTROPHORESIS; REFRACTIVE INDEX; RI; S-2238; S-2765; ULTRAVIOLET; UV; WEIGHT AVERAGE MOLECULAR WEIGHT; Α-D-N-ACETYLGLUCOSAMINE; Α-L-IDURONIC ACID; Β-D-GLUCURONIC ACID;

HEPARIN; HEPARIN LYASE; MOLECULAR WEIGHT; POLYMERIZATION; POLYSACCHARIDE-LYASES;

EID: 84886051954     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2013.09.052     Document Type: Article

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