Oxidative Stress and Balance in Neurodegenerative Diseases

Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders: Second Edition

Volumn , Issue , 2011, Pages 10-12

  Collins, George H ^a   Mondragón Rodríguez, Siddhartha ^b   Nunomura, Akihiko ^c   Zhu, Xiongwei ^d   Moreira, Paula I ^e   Smith, Mark A ^f  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITY OF YAMANASHI   (Japan)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF COIMBRA   (Portugal)

^f NONE

Author keywords

Alzheimer's disease; Antioxidants; Apoptosis; Cellular reductants; Neurofilament heavy subunit; Oxidative damage; Superoxide dismutase

Indexed keywords

EID: 84886036204     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781444341256.ch3     Document Type: Chapter

References (10)

1. Markesbery WR, Carney JM. Oxidative alterations in Alzheimer's disease. Brain Pathol 1000; 9: 133-146.
2. Sayre LM, Smith MA, Perry G. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr Med Chem 2001; 8: 721-738.
3. Sayre LM, Perry G, Smith MA. In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders. Methods Enzymol 1999; 309: 133-152.
4. Perry G, Nunomura A, Lucassen P, Lassmann H, Smith MA. Apoptosis and Alzheimer's disease. Science 1998; 282: 1268-1269.
5. Perry G, Nunomura A, Smith MA. A suicide note from Alzheimer disease neurons? Nat Med 1998; 4: 897-898.
6. Nunomura A, Perry G, Aliev G et al. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol 2001; 60: 759-767.
7. Nunomura A, Perry G, Hirai K, Aliev G et al. Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome. Ann N Y Acad Sci 1999; 893: 362-364.
8. Nunomura A, Perry G, Pappolla MA et al. Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome. J Neuropathol Exp Neurol 2000; 59: 1011-1017.
9. Perry G, Moreira PI, Siedlak SL, Nunomura A, Zhu X, Smith MA. Natural oxidant balance in Parkinson disease. Arch Neurol 2009; 66(12): 1445.
10. Wataya T, Nunomura A, Smith MA et al. High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal. J Biol Chem 2002; 277: 4644-4648.