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Volumn 6, Issue 6, 2013, Pages 1041-1053

From infection to immunotherapy: Host immune responses to bacteria at the bladder mucosa

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2B INTERFERON; BCG VACCINE; FORSKOLIN; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 84885989341     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2013.72     Document Type: Review
Times cited : (83)

References (212)
  • 2
    • 79953746223 scopus 로고    scopus 로고
    • Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder
    • Shin, K. et al. Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder. Nature 472, 110-114 (2011).
    • (2011) Nature , vol.472 , pp. 110-114
    • Shin, K.1
  • 3
    • 0016799622 scopus 로고
    • The mammalian urinary bladder: An accommodating organ
    • Hicks, R.M. The mammalian urinary bladder: An accommodating organ. Biol. Rev. Camb. Philos. Soc. 50, 215-246 (1975).
    • (1975) Biol. Rev. Camb. Philos. Soc. , vol.50 , pp. 215-246
    • Hicks, R.M.1
  • 5
    • 67349126033 scopus 로고    scopus 로고
    • Uroplakins in urothelial biology, function, and disease
    • Wu, X.R., Kong, X.P., Pellicer, A., Kreibich, G. & Sun, T.T. Uroplakins in urothelial biology, function, and disease. Kidney Int. 75, 1153-1165 (2009).
    • (2009) Kidney Int. , vol.75 , pp. 1153-1165
    • Wu, X.R.1    Kong, X.P.2    Pellicer, A.3    Kreibich, G.4    Sun, T.T.5
  • 6
    • 0036889493 scopus 로고    scopus 로고
    • Role of membrane proteins in permeability barrier function: Uroplakin ablation elevates urothelial permeability
    • Hu, P. et al. Role of membrane proteins in permeability barrier function: Uroplakin ablation elevates urothelial permeability. Am. J. Physiol. Renal Physiol. 283, F1200-F1207 (2002).
    • (2002) Am. J. Physiol. Renal Physiol. , vol.283
    • Hu, P.1
  • 7
    • 0034722328 scopus 로고    scopus 로고
    • Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux
    • Hu, P. et al. Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux. J. Cell Biol. 151, 961-972 (2000).
    • (2000) J. Cell Biol. , vol.151 , pp. 961-972
    • Hu, P.1
  • 8
    • 35848948624 scopus 로고    scopus 로고
    • Antimicrobial peptides, innate immunity, and the normally sterile urinary tract
    • Zasloff, M. Antimicrobial peptides, innate immunity, and the normally sterile urinary tract. J. Am. Soc. Nephrol. 18, 2810-2816 (2007).
    • (2007) J. Am. Soc. Nephrol. , vol.18 , pp. 2810-2816
    • Zasloff, M.1
  • 9
    • 1242336855 scopus 로고    scopus 로고
    • Viable but nonculturable bacteria are present in mouse and human urine specimens
    • Anderson, M. et al. Viable but nonculturable bacteria are present in mouse and human urine specimens. J. Clin. Microbiol. 42, 753-758 (2004).
    • (2004) J. Clin. Microbiol. , vol.42 , pp. 753-758
    • Anderson, M.1
  • 10
    • 84865339168 scopus 로고    scopus 로고
    • Integrated next-generation sequencing of 16S rDNA and metaproteomics differentiate the healthy urine microbiome from asymptomatic bacteriuria in neuropathic bladder associated with spinal cord injury
    • Fouts, D.E. et al. Integrated next-generation sequencing of 16S rDNA and metaproteomics differentiate the healthy urine microbiome from asymptomatic bacteriuria in neuropathic bladder associated with spinal cord injury. J. Transl. Med. 10, 174 (2012).
    • (2012) J. Transl. Med. , vol.10 , Issue.174
    • Fouts, D.E.1
  • 11
    • 0035100671 scopus 로고    scopus 로고
    • Viable but nonculturable uropathogenic bacteria are present in the mouse urinary tract following urinary tract infection and antibiotic therapy
    • Rivers, B. & Steck, T.R. Viable but nonculturable uropathogenic bacteria are present in the mouse urinary tract following urinary tract infection and antibiotic therapy. Urol. Res. 29, 60-66 (2001).
    • (2001) Urol. Res. , vol.29 , pp. 60-66
    • Rivers, B.1    Steck, T.R.2
  • 12
    • 80055117479 scopus 로고    scopus 로고
    • Assessing diversity of the female urine microbiota by high throughput sequencing of 16S rDNA amplicons
    • Siddiqui, H.,Nederbragt, A.J., Lagesen,K., Jeansson, S.L. & Jakobsen, K.S. Assessing diversity of the female urine microbiota by high throughput sequencing of 16S rDNA amplicons. BMC Microbiol. 11, 244 (2011).
    • (2011) BMC Microbiol. , vol.11 , pp. 244
    • Siddiqui, H.1    Nederbragt, A.J.2    Lagesen, K.3    Jeansson, S.L.4    Jakobsen, K.S.5
  • 13
    • 29144464352 scopus 로고    scopus 로고
    • Characterization of microbial communities found in the human vagina by analysis of terminal restriction fragment length polymorphisms of 16S rRNA genes
    • Coolen, M.J., Post, E., Davis, C.C. & Forney, L.J. Characterization of microbial communities found in the human vagina by analysis of terminal restriction fragment length polymorphisms of 16S rRNA genes. Appl. Environ. Microbiol. 71, 8729-8737 (2005).
    • (2005) Appl. Environ. Microbiol. , vol.71 , pp. 8729-8737
    • Coolen, M.J.1    Post, E.2    Davis, C.C.3    Forney, L.J.4
  • 14
    • 79952750340 scopus 로고    scopus 로고
    • Vaginal microbiome of reproductive-Age women
    • Ravel, J. et al. Vaginal microbiome of reproductive-Age women. Proc. Natl. Acad. Scie. USA 108 (Suppl 1), 4680-4687 (2011).
    • (2011) Proc. Natl. Acad. Scie. USA , vol.108 , Issue.SUPPL.1 , pp. 4680-4687
    • Ravel, J.1
  • 15
    • 0017661883 scopus 로고
    • The bacterial flora of the vaginal vestibule, urethra and vagina in the normal premenopausal woman
    • Pfau, A. & Sacks, T. The bacterial flora of the vaginal vestibule, urethra and vagina in the normal premenopausal woman. J. Urol. 118, 292-295 (1977).
    • (1977) J. Urol. , vol.118 , pp. 292-295
    • Pfau, A.1    Sacks, T.2
  • 16
    • 0037188917 scopus 로고    scopus 로고
    • Bacterial adhesion to target cells enhanced by shear force
    • Thomas, W.E., Trintchina, E., Forero, M., Vogel, V. & Sokurenko, E.V. Bacterial adhesion to target cells enhanced by shear force. Cell 109, 913-923 (2002).
    • (2002) Cell , vol.109 , pp. 913-923
    • Thomas, W.E.1    Trintchina, E.2    Forero, M.3    Vogel, V.4    Sokurenko, E.V.5
  • 17
    • 33751245905 scopus 로고    scopus 로고
    • The mechanical properties of E coli type 1 pili measured by atomic force microscopy techniques
    • Miller, E., Garcia, T., Hultgren, S. & Oberhauser, A.F. The mechanical properties of E. coli type 1 pili measured by atomic force microscopy techniques. Biophys. J. 91, 3848-3856 (2006).
    • (2006) Biophys. J. , vol.91 , pp. 3848-3856
    • Miller, E.1    Garcia, T.2    Hultgren, S.3    Oberhauser, A.F.4
  • 18
    • 84878160229 scopus 로고    scopus 로고
    • The shaft of the type 1 fimbriae regulates an external force to match the FimH catch bond
    • Zakrisson, J.,Wiklund, K., Axner,O. & Andersson,M. The shaft of the type 1 fimbriae regulates an external force to match the FimH catch bond. Biophys. J. 104, 2137-2148 (2013).
    • (2013) Biophys. J. , vol.104 , pp. 2137-2148
    • Zakrisson, J.1    Wiklund, K.2    Axner, O.3    Andersson, M.4
  • 19
    • 0025191204 scopus 로고
    • Bladder surface glycosaminoglycans: An epithelial permeability barrier
    • Parsons, C.L., Boychuk, D., Jones, S., Hurst, R. & Callahan, H. Bladder surface glycosaminoglycans: An epithelial permeability barrier. J. Urol. 143, 139-142 (1990).
    • (1990) J. Urol. , vol.143 , pp. 139-142
    • Parsons, C.L.1    Boychuk, D.2    Jones, S.3    Hurst, R.4    Callahan, H.5
  • 20
    • 0021194128 scopus 로고
    • Effect of ammonium on bacterial adherence to bladder transitional epithelium
    • Parsons, C.L., Stauffer, C., Mulholland, S.G. & Griffith, D.P. Effect of ammonium on bacterial adherence to bladder transitional epithelium. J. Urol. 132, 365-366 (1984).
    • (1984) J. Urol. , vol.132 , pp. 365-366
    • Parsons, C.L.1    Stauffer, C.2    Mulholland, S.G.3    Griffith, D.P.4
  • 21
    • 0017328059 scopus 로고
    • Role of surface mucin in primary antibacterial defense of bladder
    • Parsons, C.L., Greenspan, C., Moore, S.W. & Mulholland, S.G. Role of surface mucin in primary antibacterial defense of bladder. Urology 9, 48-52 (1977).
    • (1977) Urology , vol.9 , pp. 48-52
    • Parsons, C.L.1    Greenspan, C.2    Moore, S.W.3    Mulholland, S.G.4
  • 22
    • 0019602861 scopus 로고
    • Impairment of antibacterial effect of bladder surface mucin by protamine sulfate
    • Parsons, C.L., Stauffer, C. & Schmidt, J.D. Impairment of antibacterial effect of bladder surface mucin by protamine sulfate. J. Infect. Dis. 144, 180 (1981).
    • (1981) J. Infect. Dis. , vol.144 , pp. 180
    • Parsons, C.L.1    Stauffer, C.2    Schmidt, J.D.3
  • 23
    • 0023903239 scopus 로고
    • Reversible inactivation of bladder surface glycosaminoglycan antibacterial activity by protamine sulfate
    • Parsons, C.L., Stauffer, C.W. & Schmidt, J.D. Reversible inactivation of bladder surface glycosaminoglycan antibacterial activity by protamine sulfate. Infect. Immun. 56, 1341-1343 (1988).
    • (1988) Infect. Immun. , vol.56 , pp. 1341-1343
    • Parsons, C.L.1    Stauffer, C.W.2    Schmidt, J.D.3
  • 24
    • 0026544238 scopus 로고
    • Enhancement of bacillus Calmette-Guerin attachment to the urothelium by removal of the rabbit bladder mucin layer
    • Badalament, R.A. et al. Enhancement of bacillus Calmette-Guerin attachment to the urothelium by removal of the rabbit bladder mucin layer. J. Urol. 147, 482-485 (1992).
    • (1992) J. Urol. , vol.147 , pp. 482-485
    • Badalament, R.A.1
  • 25
    • 18744387422 scopus 로고    scopus 로고
    • The bladder does not appear to have a dynamic secreted continuous mucous gel layer
    • N'Dow, J., Jordan, N., Robson, C.N., Neal, D.E. & Pearson, J.P. The bladder does not appear to have a dynamic secreted continuous mucous gel layer. J. Urol. 173, 2025-2031 (2005).
    • (2005) J. Urol. , vol.173 , pp. 2025-2031
    • N'Dow, J.1    Jordan, N.2    Robson, C.N.3    Neal, D.E.4    Pearson, J.P.5
  • 26
    • 0018249743 scopus 로고
    • Secretory immunoglobulin A and G antibodies prevent adhesion of Escherichia coli to human urinary tract epithelial cells
    • Svanborg-Eden, C. & Svennerholm, A.M. Secretory immunoglobulin A and G antibodies prevent adhesion of Escherichia coli to human urinary tract epithelial cells. Infect. Immun. 22, 790-797 (1978).
    • (1978) Infect. Immun. , vol.22 , pp. 790-797
    • Svanborg-Eden, C.1    Svennerholm, A.M.2
  • 27
    • 0020537063 scopus 로고
    • Does low urinary sIgA predispose to urinary tract infectioñ
    • Riedasch, G., Heck, P., Rauterberg, E. & Ritz, E. Does low urinary sIgA predispose to urinary tract infectioñ Kidney Int. 23, 759-763 (1983).
    • (1983) Kidney Int. , vol.23 , pp. 759-763
    • Riedasch, G.1    Heck, P.2    Rauterberg, E.3    Ritz, E.4
  • 28
    • 0036259887 scopus 로고    scopus 로고
    • Characterization of the mouse beta defensin 1, Defb1, mutant mouse model
    • Morrison, G., Kilanowski, F., Davidson, D. & Dorin, J. Characterization of the mouse beta defensin 1, Defb1, mutant mouse model. Infect. Immun. 70, 3053-3060 (2002).
    • (2002) Infect. Immun. , vol.70 , pp. 3053-3060
    • Morrison, G.1    Kilanowski, F.2    Davidson, D.3    Dorin, J.4
  • 29
    • 0034097087 scopus 로고    scopus 로고
    • Structural analysis of human beta-defensin-1 and its significance in urinary tract infection
    • Hiratsuka, T. et al. Structural analysis of human beta-defensin-1 and its significance in urinary tract infection. Nephron 85, 34-40 (2000).
    • (2000) Nephron , vol.85 , pp. 34-40
    • Hiratsuka, T.1
  • 30
    • 84863141810 scopus 로고    scopus 로고
    • Human alpha defensin 5 expression in the human kidney and urinary tract
    • Spencer, J.D. et al. Human alpha defensin 5 expression in the human kidney and urinary tract. PLoS One 7, e31712 (2012).
    • (2012) PLoS One , vol.7
    • Spencer, J.D.1
  • 31
    • 0032523214 scopus 로고    scopus 로고
    • Human beta-defensin-1: An antimicrobial peptide of urogenital tissues
    • Valore, E.V. et al. Human beta-defensin-1: An antimicrobial peptide of urogenital tissues. J. Clin. Invest. 101, 1633-1642 (1998).
    • (1998) J. Clin. Invest. , vol.101 , pp. 1633-1642
    • Valore, E.V.1
  • 32
    • 33744986714 scopus 로고    scopus 로고
    • The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection
    • Chromek, M. et al. The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection. Nat. Med. 12, 636-641 (2006).
    • (2006) Nat. Med. , vol.12 , pp. 636-641
    • Chromek, M.1
  • 33
    • 78650795042 scopus 로고    scopus 로고
    • Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder
    • Hertting, O. et al. Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. PLoS One 5, e15580 (2010).
    • (2010) PLoS One , vol.5
    • Hertting, O.1
  • 34
    • 0037130950 scopus 로고    scopus 로고
    • Expression of human beta-defensins 1 and 2 in kidneys with chronic bacterial infection
    • Lehmann, J. et al. Expression of human beta-defensins 1 and 2 in kidneys with chronic bacterial infection. BMC Infect. Dis. 2, 20 (2002).
    • (2002) BMC Infect. Dis. , vol.2 , pp. 20
    • Lehmann, J.1
  • 35
    • 1342322652 scopus 로고    scopus 로고
    • Tamm-Horsfall protein knockoutmice are more prone to urinary tract infection: Rapid communication
    • Bates, J.M. et al. Tamm-Horsfall protein knockoutmice are more prone to urinary tract infection: Rapid communication. Kidney Int. 65, 791-797 (2004).
    • (2004) Kidney Int. , vol.65 , pp. 791-797
    • Bates, J.M.1
  • 36
    • 0035971077 scopus 로고    scopus 로고
    • Tamm-Horsfall protein binds to type 1 fimbriated Escherichia coli and prevents E coli from binding to uroplakin Ia and Ib receptors
    • Pak, J., Pu, Y., Zhang, Z.T., Hasty, D.L. & Wu, X.R. Tamm-Horsfall protein binds to type 1 fimbriated Escherichia coli and prevents E. coli from binding to uroplakin Ia and Ib receptors. J. Biol. Chem. 276, 9924-9930 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 9924-9930
    • Pak, J.1    Pu, Y.2    Zhang, Z.T.3    Hasty, D.L.4    Wu, X.R.5
  • 37
    • 17444381195 scopus 로고    scopus 로고
    • Tamm-Horsfall protein: A multilayered defence molecule against urinary tract infection
    • Saemann, M.D., Weichhart, T., Horl, W.H. & Zlabinger, G.J. Tamm-Horsfall protein: A multilayered defence molecule against urinary tract infection. Eur. J. Clin. Invest. 35, 227-235 (2005).
    • (2005) Eur. J. Clin. Invest. , vol.35 , pp. 227-235
    • Saemann, M.D.1    Weichhart, T.2    Horl, W.H.3    Zlabinger, G.J.4
  • 39
    • 0022633370 scopus 로고
    • Immunohistochemical analysis of the human bladder
    • Gardiner, R.A. et al. Immunohistochemical analysis of the human bladder. Br. J. Urol. 58, 19-25 (1986).
    • (1986) Br. J. Urol. , vol.58 , pp. 19-25
    • Gardiner, R.A.1
  • 40
    • 0019415855 scopus 로고
    • Demonstration and characterization of Ia-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues, but not brain
    • Hart, D.N. & Fabre, J.W. Demonstration and characterization of Ia-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues, but not brain. J. Exp. Med. 154, 347-361 (1981).
    • (1981) J. Exp. Med. , vol.154 , pp. 347-361
    • Hart, D.N.1    Fabre, J.W.2
  • 41
    • 0020356360 scopus 로고
    • Anti-Ia-reactive cells in the urinary tract of man, guinea-pig, rat andmouse
    • Hjelm, E., Forsum, U. & Klareskog, L. Anti-Ia-reactive cells in the urinary tract of man, guinea-pig, rat andmouse. Scand. J. Immunol. 16, 531-538 (1982).
    • (1982) Scand. J. Immunol. , vol.16 , pp. 531-538
    • Hjelm, E.1    Forsum, U.2    Klareskog, L.3
  • 42
    • 54049148962 scopus 로고    scopus 로고
    • CCR2 mediates homeostatic and inflammatory release of Gr1(high) monocytes from the bone marrow, but is dispensable for bladder infiltration in bacterial urinary tract infection
    • Engel, D.R. et al. CCR2 mediates homeostatic and inflammatory release of Gr1(high) monocytes from the bone marrow, but is dispensable for bladder infiltration in bacterial urinary tract infection. J. Immunol. 181, 5579-5586 (2008).
    • (2008) J. Immunol. , vol.181 , pp. 5579-5586
    • Engel, D.R.1
  • 43
    • 0037388307 scopus 로고    scopus 로고
    • Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli
    • Schilling, J.D., Martin, S.M., Hung, C.S., Lorenz, R.G. & Hultgren, S.J. Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli. Proc. Natl. Acad. Sci. USA 100, 4203-4208 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 4203-4208
    • Schilling, J.D.1    Martin, S.M.2    Hung, C.S.3    Lorenz, R.G.4    Hultgren, S.J.5
  • 44
    • 84867740805 scopus 로고    scopus 로고
    • Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
    • Gautier, E.L. et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat. Immunol. 13, 1118-1128 (2012).
    • (2012) Nat. Immunol. , vol.13 , pp. 1118-1128
    • Gautier, E.L.1
  • 45
    • 84865418665 scopus 로고    scopus 로고
    • Deciphering the transcriptional network of the dendritic cell lineage
    • Miller, J.C. et al. Deciphering the transcriptional network of the dendritic cell lineage. Nat. Immunol. 13, 888-899 (2012).
    • (2012) Nat. Immunol. , vol.13 , pp. 888-899
    • Miller, J.C.1
  • 46
    • 0028364928 scopus 로고
    • Lymphocyte sub-populations in the bladderwall in normal bladder, bacterial cystitis and interstitial cystitis
    • Christmas, T.J. Lymphocyte sub-populations in the bladderwall in normal bladder, bacterial cystitis and interstitial cystitis. Br. J. Urol. 73, 508-515 (1994).
    • (1994) Br. J. Urol. , vol.73 , pp. 508-515
    • Christmas, T.J.1
  • 47
    • 55749105564 scopus 로고    scopus 로고
    • G-CSF induction early in uropathogenic Escherichia coli infection of the urinary tract modulates host immunity
    • Ingersoll, M.A., Kline, K.A.,Nielsen,H.V. & Hultgren, S.J. G-CSF induction early in uropathogenic Escherichia coli infection of the urinary tract modulates host immunity. Cell. Microbiol. 10, 2568-2578 (2008).
    • (2008) Cell. Microbiol. , vol.10 , pp. 2568-2578
    • Ingersoll, M.A.1    Kline, K.A.2    Nielsen, H.V.3    Hultgren, S.J.4
  • 48
    • 77949888220 scopus 로고    scopus 로고
    • The innate immune response to uropathogenic Escherichia coli involves IL-17A in a murine model of urinary tract infection
    • Sivick, K.E., Schaller, M.A., Smith, S.N. Mobley,H.L. The innate immune response to uropathogenic Escherichia coli involves IL-17A in a murine model of urinary tract infection. J. Immunol. 184, 2065-2075 (2010).
    • (2010) J. Immunol. , vol.184 , pp. 2065-2075
    • Sivick, K.E.1    Schaller, M.A.2    Smith, S.N.3    Mobley, H.L.4
  • 49
    • 0032862854 scopus 로고    scopus 로고
    • Susceptibility of immunodeficient gene-knockout mice to urinary tract infection
    • Jones-Carson, J., Balish, E. & Uehling, D.T. Susceptibility of immunodeficient gene-knockout mice to urinary tract infection. J. Urol. 161, 338-341 (1999).
    • (1999) J. Urol. , vol.161 , pp. 338-341
    • Jones-Carson, J.1    Balish, E.2    Uehling, D.T.3
  • 50
    • 0027178514 scopus 로고
    • Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- Alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain
    • Porcelli, S., Yockey, C.E., Brenner, M.B. & Balk, S.P. Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- Alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain. J. Exp. Med. 178, 1-16 (1993).
    • (1993) J. Exp. Med. , vol.178 , pp. 1-16
    • Porcelli, S.1    Yockey, C.E.2    Brenner, M.B.3    Balk, S.P.4
  • 51
    • 0033591698 scopus 로고    scopus 로고
    • An invariant Tcell receptor alpha chain defines a novel TAPindependent major histocompatibility complex class Ib-restricted alpha/ betaTcell subpopulationinmammals
    • Tilloy, F. et al. An invariant Tcell receptor alpha chain defines a novel TAPindependent major histocompatibility complex class Ib-restricted alpha/ betaTcell subpopulationinmammals. J.Exp.Med.189, 1907-1921(1999).
    • (1999) J.Exp.Med. , vol.189 , pp. 1907-1921
    • Tilloy, F.1
  • 52
    • 0037434974 scopus 로고    scopus 로고
    • Selection of evolutionarily conserved mucosal-Associated invariant T cells by MR1
    • Treiner, E. et al. Selection of evolutionarily conserved mucosal-Associated invariant T cells by MR1. Nature 422, 164-169 (2003).
    • (2003) Nature , vol.422 , pp. 164-169
    • Treiner, E.1
  • 53
    • 40049083827 scopus 로고    scopus 로고
    • Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
    • Zheng, Y. et al. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nat. Med. 14, 282-289 (2008).
    • (2008) Nat. Med. , vol.14 , pp. 282-289
    • Zheng, Y.1
  • 54
    • 0030813508 scopus 로고    scopus 로고
    • Diagnosis and treatment of uncomplicated urinary tract infection
    • Hooton, T.M. & Stamm, W.E. Diagnosis and treatment of uncomplicated urinary tract infection. Infect. Dis. Clin. North Am. 11, 551-581 (1997).
    • (1997) Infect. Dis. Clin. North Am. , vol.11 , pp. 551-581
    • Hooton, T.M.1    Stamm, W.E.2
  • 55
    • 0038076041 scopus 로고    scopus 로고
    • Medical and economic impact of extraintestinal infections due to Escherichia coli: Focus on an increasingly important endemic problem
    • Russo, T.A. & Johnson, J.R. Medical and economic impact of extraintestinal infections due to Escherichia coli: Focus on an increasingly important endemic problem. Microbes Infect. 5, 449-456 (2003).
    • (2003) Microbes Infect. , vol.5 , pp. 449-456
    • Russo, T.A.1    Johnson, J.R.2
  • 56
    • 3042793159 scopus 로고    scopus 로고
    • Acute uncomplicated cystitis in an era of increasing antibiotic resistance: A proposed approach toempirical therapy
    • Hooton, T.M., Besser, R., Foxman, B., Fritsche, T.R. & Nicolle, L.E. Acute uncomplicated cystitis in an era of increasing antibiotic resistance: A proposed approach toempirical therapy. Clin. Infect. Dis. 39, 75-80 (2004).
    • (2004) Clin. Infect. Dis. , vol.39 , pp. 75-80
    • Hooton, T.M.1    Besser, R.2    Foxman, B.3    Fritsche, T.R.4    Nicolle, L.E.5
  • 57
    • 0037300154 scopus 로고    scopus 로고
    • The etiology of urinary tract infection: Traditional and emerging pathogens
    • Ronald, A. The etiology of urinary tract infection: Traditional and emerging pathogens. Dis. Mon. 49, 71-82 (2003).
    • (2003) Dis. Mon. , vol.49 , pp. 71-82
    • Ronald, A.1
  • 58
    • 0028945986 scopus 로고
    • FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae
    • Jones, C.H. et al. FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae. Proc. Natl. Acad. Sci. USA 92, 2081-2085 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2081-2085
    • Jones, C.H.1
  • 59
    • 0034747254 scopus 로고    scopus 로고
    • Uroplakin Ia is the urothelial receptor for uropathogenic Escherichia coli: Evidence from in vitro FimH binding
    • Zhou, G. et al. Uroplakin Ia is the urothelial receptor for uropathogenic Escherichia coli: Evidence from in vitro FimH binding. J. Cell Sci. 114, 4095-4103 (2001).
    • (2001) J. Cell Sci. , vol.114 , pp. 4095-4103
    • Zhou, G.1
  • 60
    • 33744964885 scopus 로고    scopus 로고
    • Distinct glycan structures of uroplakins Ia and Ib: Structural basis for the selective binding of FimH adhesin to uroplakin Ia
    • Xie, B. et al. Distinct glycan structures of uroplakins Ia and Ib: Structural basis for the selective binding of FimH adhesin to uroplakin Ia. J. Biol. Chem. 281, 14644-14653 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 14644-14653
    • Xie, B.1
  • 61
    • 0029796909 scopus 로고    scopus 로고
    • In vitro binding of type 1-fimbriated Escherichia coli to uroplakins Ia and Ib: Relation to urinary tract infections
    • Wu, X.R., Sun, T.T. & Medina, J.J. In vitro binding of type 1-fimbriated Escherichia coli to uroplakins Ia and Ib: Relation to urinary tract infections. Proc. Natl. Acad. Sci. USA 93, 9630-9635 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9630-9635
    • Wu, X.R.1    Sun, T.T.2    Medina, J.J.3
  • 62
    • 0022353848 scopus 로고
    • Role of type 1 pili and effects of phase variation on lower urinary tract infections produced by Escherichia coli
    • Hultgren, S.J., Porter, T.N., Schaeffer, A.J. & Duncan, J.L. Role of type 1 pili and effects of phase variation on lower urinary tract infections produced by Escherichia coli. Infect. Immun. 50, 370-377 (1985).
    • (1985) Infect. Immun. , vol.50 , pp. 370-377
    • Hultgren, S.J.1    Porter, T.N.2    Schaeffer, A.J.3    Duncan, J.L.4
  • 63
    • 0023096182 scopus 로고
    • Relationship of type 1 pilus expression in Escherichia coli to ascending urinary tract infections in mice
    • Schaeffer, A.J., Schwan,W.R., Hultgren, S.J. &Duncan, J.L. Relationship of type 1 pilus expression in Escherichia coli to ascending urinary tract infections in mice. Infect. Immun. 55, 373-380 (1987).
    • (1987) Infect. Immun. , vol.55 , pp. 373-380
    • Schaeffer, A.J.1    Schwan, W.R.2    Hultgren, S.J.3    Duncan, J.L.4
  • 65
    • 0032553579 scopus 로고    scopus 로고
    • Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli
    • Mulvey, M.A. et al. Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli. Science 282, 1494-1497 (1998).
    • (1998) Science , vol.282 , pp. 1494-1497
    • Mulvey, M.A.1
  • 66
    • 46449100724 scopus 로고    scopus 로고
    • Molecular variations in Klebsiella pneumoniae and Escherichia coli FimH affect function and pathogenesis in the urinary tract
    • Rosen, D.A. et al. Molecular variations in Klebsiella pneumoniae and Escherichia coli FimH affect function and pathogenesis in the urinary tract. Infect. Immun. 76, 3346-3356 (2008).
    • (2008) Infect. Immun. , vol.76 , pp. 3346-3356
    • Rosen, D.A.1
  • 67
    • 58649088485 scopus 로고    scopus 로고
    • Uropathogenic Escherichia coli invades host cells via an HDAC6-modulated microtubule-dependent pathway
    • Dhakal, B.K. Mulvey,M.A. Uropathogenic Escherichia coli invades host cells via an HDAC6-modulated microtubule-dependent pathway. J. Biol. Chem. 284, 446-454 (2009).
    • (2009) J. Biol. Chem. , vol.284 , pp. 446-454
    • Dhakal, B.K.1    Mulvey, M.A.2
  • 68
    • 0036158774 scopus 로고    scopus 로고
    • Requirement of Rho-family GTPases in the invasion of Type 1-piliated uropathogenic Escherichia coli
    • Martinez, J.J. & Hultgren, S.J. Requirement of Rho-family GTPases in the invasion of Type 1-piliated uropathogenic Escherichia coli. Cell. Microbiol. 4, 19-28 (2002).
    • (2002) Cell. Microbiol. , vol.4 , pp. 19-28
    • Martinez, J.J.1    Hultgren, S.J.2
  • 69
    • 2442487900 scopus 로고    scopus 로고
    • Bacterial penetration of bladder epithelium through lipid rafts
    • Duncan, M.J., Li, G., Shin, J.S., Carson, J.L. & Abraham, S.N. Bacterial penetration of bladder epithelium through lipid rafts. J. Biol. Chem. 279, 18944-18951 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 18944-18951
    • Duncan, M.J.1    Li, G.2    Shin, J.S.3    Carson, J.L.4    Abraham, S.N.5
  • 70
    • 55749095583 scopus 로고    scopus 로고
    • Clathrin AP-2, and the NPXY-binding subset of alternate endocytic adaptors facilitate FimH-mediated bacterial invasion of host cells
    • Eto, D.S., Gordon, H.B., Dhakal, B.K., Jones, T.A. & Mulvey, M.A. Clathrin, AP-2, and the NPXY-binding subset of alternate endocytic adaptors facilitate FimH-mediated bacterial invasion of host cells. Cell. Microbiol. 10, 2553-2567 (2008).
    • (2008) Cell. Microbiol. , vol.10 , pp. 2553-2567
    • Eto, D.S.1    Gordon, H.B.2    Dhakal, B.K.3    Jones, T.A.4    Mulvey, M.A.5
  • 71
    • 78651285263 scopus 로고    scopus 로고
    • Dynamin2- And endothelial nitric oxide synthase-regulated invasion of bladder epithelial cells by uropathogenic Escherichia coli
    • Wang, Z. et al. Dynamin2- And endothelial nitric oxide synthase-regulated invasion of bladder epithelial cells by uropathogenic Escherichia coli. J. Cell Biol. 192, 101-110 (2011).
    • (2011) J. Cell Biol. , vol.192 , pp. 101-110
    • Wang, Z.1
  • 72
    • 0842299578 scopus 로고    scopus 로고
    • Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis
    • Justice, S.S. et al. Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis. Proc. Natl. Acad. Sci. USA 101, 1333-1338 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 1333-1338
    • Justice, S.S.1
  • 73
    • 4444277553 scopus 로고    scopus 로고
    • Intracellular bacterial communities of uropathogenic Escherichia coli in urinary tract pathogenesis
    • Anderson,G.G., Dodson,K.W., Hooton, T.M. & Hultgren, S.J. Intracellular bacterial communities of uropathogenic Escherichia coli in urinary tract pathogenesis. Trends Microbiol. 12, 424-430 (2004).
    • (2004) Trends Microbiol. , vol.12 , pp. 424-430
    • Anderson, G.G.1    Dodson, K.W.2    Hooton, T.M.3    Hultgren, S.J.4
  • 74
    • 0038048322 scopus 로고    scopus 로고
    • Intracellular bacterial biofilm-like pods in urinary tract infections
    • Anderson,G.G. et al. Intracellular bacterial biofilm-like pods in urinary tract infections. Science 301, 105-107 (2003).
    • (2003) Science , vol.301 , pp. 105-107
    • Anderson, G.G.1
  • 75
    • 46449115900 scopus 로고    scopus 로고
    • Utilization of an intracellular bacterial community pathway in Klebsiella pneumoniae urinary tract infection and the effects of FimK on type 1 pilus expression
    • Rosen, D.A. et al. Utilization of an intracellular bacterial community pathway in Klebsiella pneumoniae urinary tract infection and the effects of FimK on type 1 pilus expression. Infect. Immun. 76, 3337-3345 (2008).
    • (2008) Infect. Immun. , vol.76 , pp. 3337-3345
    • Rosen, D.A.1
  • 76
    • 0034978222 scopus 로고    scopus 로고
    • Establishment of a persistent Escherichia coli reservoir during the acute phase of a bladder infection
    • Mulvey,M.A., Schilling, J.D. & Hultgren, S.J. Establishment of a persistent Escherichia coli reservoir during the acute phase of a bladder infection. Infect. Immun. 69, 4572-4579 (2001).
    • (2001) Infect. Immun. , vol.69 , pp. 4572-4579
    • Mulvey, M.A.1    Schilling, J.D.2    Hultgren, S.J.3
  • 77
    • 38049053061 scopus 로고    scopus 로고
    • Detection of intracellular bacterial communities in human urinary tract infection
    • Rosen, D.A., Hooton, T.M.,Stamm,W.E., Humphrey,P.A. & Hultgren,S.J. Detection of intracellular bacterial communities in human urinary tract infection. PLoS Med. 4, e329 (2007).
    • (2007) PLoS Med. , vol.4
    • Rosen, D.A.1    Hooton, T.M.2    Stamm, W.E.3    Humphrey, P.A.4    Hultgren, S.J.5
  • 78
    • 69149091826 scopus 로고    scopus 로고
    • Prospective cohort study of microbial and inflammatory events immediately preceding Escherichia coli recurrent urinary tract infection in women
    • Czaja, C.A. et al. Prospective cohort study of microbial and inflammatory events immediately preceding Escherichia coli recurrent urinary tract infection in women. J. Infect. Dis. 200, 528-536 (2009).
    • (2009) J. Infect. Dis. , vol.200 , pp. 528-536
    • Czaja, C.A.1
  • 79
    • 84878289779 scopus 로고    scopus 로고
    • Genomic diversity and fitness of E COLI strains recovered from the intestinal and urinary tracts of women with recurrent urinary tract infection
    • 184ra160
    • Chen, S.L. et al. Genomic diversity and fitness of E. COLI strains recovered from the intestinal and urinary tracts of women with recurrent urinary tract infection. Sci. Transl. Med. 5, 184ra160 (2013).
    • (2013) Sci. Transl. Med. , vol.5
    • Chen, S.L.1
  • 80
    • 33749012527 scopus 로고    scopus 로고
    • Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract
    • Mysorekar, I.U. & Hultgren, S.J. Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract. Proc. Natl. Acad. Sci. USA 103, 14170-14175 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 14170-14175
    • Mysorekar, I.U.1    Hultgren, S.J.2
  • 81
    • 0036892961 scopus 로고    scopus 로고
    • Effect of trimethoprimsulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coli
    • Schilling, J.D., Lorenz, R.G. & Hultgren, S.J. Effect of trimethoprimsulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coli. Infect. Immun. 70, 7042-7049 (2002).
    • (2002) Infect. Immun. , vol.70 , pp. 7042-7049
    • Schilling, J.D.1    Lorenz, R.G.2    Hultgren, S.J.3
  • 82
    • 16244413193 scopus 로고    scopus 로고
    • Enterococcus faecalis tropism for the kidneys in the urinary tract of C57BL/6J mice
    • Kau, A.L. et al. Enterococcus faecalis tropism for the kidneys in the urinary tract of C57BL/6J mice. Infect. Immun. 73, 2461-2468 (2005).
    • (2005) Infect. Immun. , vol.73 , pp. 2461-2468
    • Kau, A.L.1
  • 83
    • 77951236115 scopus 로고    scopus 로고
    • Characterization of a novel murine model of Staphylococcus saprophyticus urinary tract infection reveals roles for Ssp and SdrI in virulence
    • Kline, K.A. et al. Characterization of a novel murine model of Staphylococcus saprophyticus urinary tract infection reveals roles for Ssp and SdrI in virulence. Infect. Immun. 78, 1943-1951 (2010).
    • (2010) Infect. Immun. , vol.78 , pp. 1943-1951
    • Kline, K.A.1
  • 84
    • 84878249531 scopus 로고    scopus 로고
    • Microbial biofilm formation and catheter-Associated bacteriuria in patients with suprapubic catheterisation
    • Bonkat, G. et al. Microbial biofilm formation and catheter-Associated bacteriuria in patients with suprapubic catheterisation. World J. Urol. 31, 565-571 (2012).
    • (2012) World J. Urol. , vol.31 , pp. 565-571
    • Bonkat, G.1
  • 85
    • 80053912099 scopus 로고    scopus 로고
    • Proteus mirabilis biofilms and catheterassociated urinary tract infections
    • Jacobsen, S.M. & Shirtliff, M.E. Proteus mirabilis biofilms and catheterassociated urinary tract infections. Virulence 2, 460-465 (2011).
    • (2011) Virulence , vol.2 , pp. 460-465
    • Jacobsen, S.M.1    Shirtliff, M.E.2
  • 86
    • 77955654591 scopus 로고    scopus 로고
    • Host-pathogen interactions in urinary tract infection
    • Nielubowicz, G.R. & Mobley, H.L. Host-pathogen interactions in urinary tract infection. Nat. Rev. Urol. 7, 430-441 (2010).
    • (2010) Nat. Rev. Urol. , vol.7 , pp. 430-441
    • Nielubowicz, G.R.1    Mobley, H.L.2
  • 87
    • 67650086639 scopus 로고    scopus 로고
    • Diversity of group B streptococcus serotypes causing urinary tract infection in adults
    • Ulett, K.B. et al. Diversity of group B streptococcus serotypes causing urinary tract infection in adults. J. Clin. Microbiol. 47, 2055-2060 (2009).
    • (2009) J. Clin. Microbiol. , vol.47 , pp. 2055-2060
    • Ulett, K.B.1
  • 88
    • 84870789453 scopus 로고    scopus 로고
    • Immune modulation by group B Streptococcus influences host susceptibility to urinary tract infection by uropathogenic Escherichia coli
    • Kline, K.A., Schwartz, D.J., Gilbert, N.M., Hultgren, S.J. & Lewis, A.L. Immune modulation by group B Streptococcus influences host susceptibility to urinary tract infection by uropathogenic Escherichia coli. Infect. Immun. 80, 4186-4194 (2012).
    • (2012) Infect. Immun. , vol.80 , pp. 4186-4194
    • Kline, K.A.1    Schwartz, D.J.2    Gilbert, N.M.3    Hultgren, S.J.4    Lewis, A.L.5
  • 89
    • 80052329537 scopus 로고    scopus 로고
    • Immune activation and suppression by groupBstreptococcus in a murine model of urinary tract infection
    • Kline, K.A., Schwartz, D.J., Lewis, W.G., Hultgren, S.J. & Lewis, A.L. Immune activation and suppression by groupBstreptococcus in a murine model of urinary tract infection. Infect. Immun. 79, 3588-3595 (2011).
    • (2011) Infect. Immun. , vol.79 , pp. 3588-3595
    • Kline, K.A.1    Schwartz, D.J.2    Lewis, W.G.3    Hultgren, S.J.4    Lewis, A.L.5
  • 91
    • 79952679401 scopus 로고    scopus 로고
    • Human antimicrobial peptide LL-37 inhibits adhesion of Candida albicans by interacting with yeast cell-wall carbohydrates
    • Tsai, P.W., Yang, C.Y., Chang, H.T. & Lan, C.Y. Human antimicrobial peptide LL-37 inhibits adhesion of Candida albicans by interacting with yeast cell-wall carbohydrates. PLoS One 6, e17755 (2011).
    • (2011) PLoS One , vol.6
    • Tsai, P.W.1    Yang, C.Y.2    Chang, H.T.3    Lan, C.Y.4
  • 92
    • 0035863909 scopus 로고    scopus 로고
    • Bacterial invasion augments epithelial cytokine responses to Escherichia coli through a lipopolysaccharide-dependent mechanism
    • Schilling, J.D.,Mulvey, M.A., Vincent, C.D., Lorenz, R.G. & Hultgren, S.J. Bacterial invasion augments epithelial cytokine responses to Escherichia coli through a lipopolysaccharide-dependent mechanism. J. Immunol. 166, 1148-1155 (2001).
    • (2001) J. Immunol. , vol.166 , pp. 1148-1155
    • Schilling, J.D.1    Mulvey, M.A.2    Vincent, C.D.3    Lorenz, R.G.4    Hultgren, S.J.5
  • 93
    • 0021703558 scopus 로고
    • Difference in susceptibility to gram-negative urinary tract infection between C3H/HeJ and C3H/HeN mice
    • Hagberg, L. et al. Difference in susceptibility to gram-negative urinary tract infection between C3H/HeJ and C3H/HeN mice. Infect. Immun. 46, 839-844 (1984).
    • (1984) Infect. Immun. , vol.46 , pp. 839-844
    • Hagberg, L.1
  • 94
    • 0033389454 scopus 로고    scopus 로고
    • Neutrophil recruitment and resistance to urinary tract infection
    • Haraoka, M. et al. Neutrophil recruitment and resistance to urinary tract infection. J. Infect. Dis. 180, 1220-1229 (1999).
    • (1999) J. Infect. Dis. , vol.180 , pp. 1220-1229
    • Haraoka, M.1
  • 95
    • 78649975616 scopus 로고    scopus 로고
    • Association of Toll-like receptor 4 gene polymorphism and expression with urinary tract infection types in adults
    • Yin, X. et al. Association of Toll-like receptor 4 gene polymorphism and expression with urinary tract infection types in adults. PLoS One 5, e14223 (2010).
    • (2010) PLoS One , vol.5
    • Yin, X.1
  • 96
    • 52649089058 scopus 로고    scopus 로고
    • Innate and adaptive immune responses in the urinary tract
    • Song, J. & Abraham, S.N. Innate and adaptive immune responses in the urinary tract. Eur. J. Clin. Invest. 38 (Suppl 2), 21-28 (2008).
    • (2008) Eur. J. Clin. Invest. , vol.38 , Issue.SUPPL.2 , pp. 21-28
    • Song, J.1    Abraham, S.N.2
  • 97
    • 34247105910 scopus 로고    scopus 로고
    • Cutting edge: Tlr5-/- mice are more susceptible to Escherichia coli urinary tract infection
    • Andersen-Nissen, E. et al. Cutting edge: Tlr5-/- mice are more susceptible to Escherichia coli urinary tract infection. J. Immunol. 178, 4717-4720 (2007).
    • (2007) J. Immunol. , vol.178 , pp. 4717-4720
    • Andersen-Nissen, E.1
  • 98
    • 1542377424 scopus 로고    scopus 로고
    • A toll-like receptor that prevents infection by uropathogenic bacteria
    • Zhang, D. et al. A toll-like receptor that prevents infection by uropathogenic bacteria. Science 303, 1522-1526 (2004).
    • (2004) Science , vol.303 , pp. 1522-1526
    • Zhang, D.1
  • 99
    • 32944465549 scopus 로고    scopus 로고
    • Mechanism of pathogen-specific TLR4 activation in the mucosa: Fimbriae, recognition receptors and adaptor protein selection
    • Fischer, H., Yamamoto, M., Akira, S., Beutler, B. & Svanborg, C. Mechanism of pathogen-specific TLR4 activation in the mucosa: Fimbriae, recognition receptors and adaptor protein selection. Eur. J. Immunol. 36, 267-277 (2006).
    • (2006) Eur. J. Immunol. , vol.36 , pp. 267-277
    • Fischer, H.1    Yamamoto, M.2    Akira, S.3    Beutler, B.4    Svanborg, C.5
  • 100
    • 0031839856 scopus 로고    scopus 로고
    • Time course and host responses to Escherichia coli urinary tract infection in genetically distinct mouse strains
    • Hopkins, W.J., Gendron-Fitzpatrick, A., Balish, E. & Uehling, D.T. Time course and host responses to Escherichia coli urinary tract infection in genetically distinct mouse strains. Infect. Immun. 66, 2798-2802 (1998).
    • (1998) Infect. Immun. , vol.66 , pp. 2798-2802
    • Hopkins, W.J.1    Gendron-Fitzpatrick, A.2    Balish, E.3    Uehling, D.T.4
  • 101
    • 0023176617 scopus 로고
    • Neutrophil recruitment and bacterial clearance correlated with LPS responsiveness in local gram-negative infection
    • Shahin, R.D., Engberg, I., Hagberg, L. & Svanborg Eden, C. Neutrophil recruitment and bacterial clearance correlated with LPS responsiveness in local gram-negative infection. J. Immunol. 138, 3475-3480 (1987).
    • (1987) J. Immunol. , vol.138 , pp. 3475-3480
    • Shahin, R.D.1    Engberg, I.2    Hagberg, L.3    Svanborg Eden, C.4
  • 102
    • 52649116492 scopus 로고    scopus 로고
    • TLR- And CXCR1-dependent innate immunity: Insights into the genetics of urinary tract infections
    • Ragnarsdottir, B. et al. TLR- And CXCR1-dependent innate immunity: Insights into the genetics of urinary tract infections. Eur. J. Clin. Invest. 38 (Suppl 2), 12-20 (2008).
    • (2008) Eur. J. Clin. Invest. , vol.38 , Issue.SUPPL.2 , pp. 12-20
    • Ragnarsdottir, B.1
  • 103
    • 77956561398 scopus 로고    scopus 로고
    • Toll-like receptor 4 promoter polymorphisms: Common TLR4 variants may protect against severe urinary tract infection
    • Ragnarsdottir, B. et al. Toll-like receptor 4 promoter polymorphisms: Common TLR4 variants may protect against severe urinary tract infection. PLoS One 5, e10734 (2010).
    • (2010) PLoS One , vol.5
    • Ragnarsdottir, B.1
  • 104
    • 34247187130 scopus 로고    scopus 로고
    • Reduced toll-like receptor 4 expression in children with asymptomatic bacteriuria
    • Ragnarsdottir, B. et al. Reduced toll-like receptor 4 expression in children with asymptomatic bacteriuria. J. Infect. Dis. 196, 475-484 (2007).
    • (2007) J. Infect. Dis. , vol.196 , pp. 475-484
    • Ragnarsdottir, B.1
  • 105
    • 69249230794 scopus 로고    scopus 로고
    • Uropathogenic E coli adhesin-induced host cell receptor conformational changes: Implications in transmembrane signaling transduction
    • Wang,H., Min, G.,Glockshuber, R., Sun, T.T. & Kong, X.P. Uropathogenic E. coli adhesin-induced host cell receptor conformational changes: Implications in transmembrane signaling transduction. J. Mol. Biol. 392, 352-361 (2009).
    • (2009) J. Mol. Biol. , vol.392 , pp. 352-361
    • Wang, H.1    Min, G.2    Glockshuber, R.3    Sun, T.T.4    Kong, X.P.5
  • 106
    • 33748038042 scopus 로고    scopus 로고
    • Uropathogenic Escherichia coli induces extrinsic and intrinsic cascades to initiate urothelial apoptosis
    • Klumpp, D.J. et al. Uropathogenic Escherichia coli induces extrinsic and intrinsic cascades to initiate urothelial apoptosis. Infect. Immun. 74, 5106-5113 (2006).
    • (2006) Infect. Immun. , vol.74 , pp. 5106-5113
    • Klumpp, D.J.1
  • 107
    • 0024448664 scopus 로고
    • Interleukin-6 induced at mucosal surfaces by gramnegative bacterial infection
    • de Man, P. et al. Interleukin-6 induced at mucosal surfaces by gramnegative bacterial infection. Infect Immun 57, 3383-3388 (1989).
    • (1989) Infect Immun , vol.57 , pp. 3383-3388
    • De Man, P.1
  • 109
    • 0027516456 scopus 로고
    • Elevated interleukin-8 levels in the urine of patients with urinary tract infections
    • Ko, Y.C. et al. Elevated interleukin-8 levels in the urine of patients with urinary tract infections. Infect. Immun. 61, 1307-1314 (1993).
    • (1993) Infect. Immun. , vol.61 , pp. 1307-1314
    • Ko, Y.C.1
  • 110
    • 0029087228 scopus 로고
    • Escherichia coli induces transuroepithelial neutrophil migration by an intercellular adhesion molecule-1-dependent mechanism
    • Agace, W.W., Patarroyo, M., Svensson, M., Carlemalm, E. & Svanborg, C. Escherichia coli induces transuroepithelial neutrophil migration by an intercellular adhesion molecule-1-dependent mechanism. Infect. Immun. 63, 4054-4062 (1995).
    • (1995) Infect. Immun. , vol.63 , pp. 4054-4062
    • Agace, W.W.1    Patarroyo, M.2    Svensson, M.3    Carlemalm, E.4    Svanborg, C.5
  • 111
    • 84874285483 scopus 로고    scopus 로고
    • Mast cell interleukin-10 drives localized tolerance in chronic bladder infection
    • Chan, C.Y. St, John, A.L. & Abraham, S.N.Mast cell interleukin-10 drives localized tolerance in chronic bladder infection. Immunity 38, 349-359 (2013).
    • (2013) Immunity , vol.38 , pp. 349-359
    • Chan, C.Y.1    St John, A.L.2    Abraham, S.N.3
  • 112
    • 84855989754 scopus 로고    scopus 로고
    • Innate transcriptional networks activated in bladder in response to uropathogenic Escherichia coli drive diverse biological pathways and rapid synthesis of IL-10 for defense against bacterial urinary tract infection
    • Duell, B.L. et al. Innate transcriptional networks activated in bladder in response to uropathogenic Escherichia coli drive diverse biological pathways and rapid synthesis of IL-10 for defense against bacterial urinary tract infection. J. Immunol. 188, 781-792 (2012).
    • (2012) J. Immunol. , vol.188 , pp. 781-792
    • Duell, B.L.1
  • 114
    • 0037714789 scopus 로고
    • Simplified quantitative methods for bacteriuria and pyuria
    • McGeachie, J. & Kennedy, A.C. Simplified quantitative methods for bacteriuria and pyuria. J. Clin. Pathol. 16, 32-38 (1963).
    • (1963) J. Clin. Pathol. , vol.16 , pp. 32-38
    • McGeachie, J.1    Kennedy, A.C.2
  • 117
    • 0028203807 scopus 로고
    • Polymorphonuclear leukocyte transmigration promotes invasion of colonic epithelial monolayer by Shigella flexneri
    • Perdomo, J.J., Gounon, P. & Sansonetti, P.J. Polymorphonuclear leukocyte transmigration promotes invasion of colonic epithelial monolayer by Shigella flexneri. J. Clin. Invest. 93, 633-643 (1994).
    • (1994) J. Clin. Invest. , vol.93 , pp. 633-643
    • Perdomo, J.J.1    Gounon, P.2    Sansonetti, P.J.3
  • 118
    • 77958148066 scopus 로고    scopus 로고
    • Early severe inflammatory responses to uropathogenic E coli predispose to chronic and recurrent urinary tract infection
    • Hannan, T.J., Mysorekar, I.U., Hung, C.S., Isaacson-Schmid, M.L. & Hultgren, S.J. Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection. PLoS Pathog. 6, e1001042 (2010).
    • (2010) PLoS Pathog , vol.6
    • Hannan, T.J.1    Mysorekar, I.U.2    Hung, C.S.3    Isaacson-Schmid, M.L.4    Hultgren, S.J.5
  • 119
    • 0027416819 scopus 로고
    • Congenital immunodeficiencies in mice increase susceptibility to urinary tract infection
    • Hopkins, W.J., James, L.J., Balish, E. & Uehling, D.T. Congenital immunodeficiencies in mice increase susceptibility to urinary tract infection. J. Urol. 149, 922-925 (1993).
    • (1993) J. Urol. , vol.149 , pp. 922-925
    • Hopkins, W.J.1    James, L.J.2    Balish, E.3    Uehling, D.T.4
  • 120
    • 67650659130 scopus 로고    scopus 로고
    • A live-Attenuated vaccine for the treatment of urinary tract infection by uropathogenic Escherichia coli
    • Billips, B.K., Yaggie, R.E., Cashy, J.P., Schaeffer, A.J. & Klumpp, D.J. A live-Attenuated vaccine for the treatment of urinary tract infection by uropathogenic Escherichia coli. J. Infect. Dis. 200, 263-272 (2009).
    • (2009) J. Infect. Dis. , vol.200 , pp. 263-272
    • Billips, B.K.1    Yaggie, R.E.2    Cashy, J.P.3    Schaeffer, A.J.4    Klumpp, D.J.5
  • 121
    • 0030948568 scopus 로고    scopus 로고
    • Prevention of mucosal Escherichia coli infection by FimH-Adhesin-based systemic vaccination
    • Langermann, S. et al. Prevention of mucosal Escherichia coli infection by FimH-Adhesin-based systemic vaccination. Science 276, 607-611 (1997).
    • (1997) Science , vol.276 , pp. 607-611
    • Langermann, S.1
  • 123
    • 0025989203 scopus 로고
    • Immunization against urinary tract infection with a multi-valent vaginal vaccine
    • Uehling, D.T., James, L.J., Hopkins, W.J. & Balish, E. Immunization against urinary tract infection with a multi-valent vaginal vaccine. J. Urol. 146, 223-226 (1991).
    • (1991) J. Urol. , vol.146 , pp. 223-226
    • Uehling, D.T.1    James, L.J.2    Hopkins, W.J.3    Balish, E.4
  • 124
    • 0028116356 scopus 로고
    • Phase I clinical trial of vaginal mucosal immunization for recurrent urinary tract infection
    • Uehling, D.T.,Hopkins,W.J., Dahmer, L.A. & Balish, E. Phase I clinical trial of vaginal mucosal immunization for recurrent urinary tract infection. J. Urol. 152, 2308-2311 (1994).
    • (1994) J. Urol. , vol.152 , pp. 2308-2311
    • Uehling, D.T.1    Hopkins, W.J.2    Dahmer, L.A.3    Balish, E.4
  • 125
    • 0031003792 scopus 로고    scopus 로고
    • Vaginal mucosal immunization for recurrent urinary tract infection: Phase II clinical trial
    • Uehling, D.T., Hopkins, W.J., Balish, E., Xing, Y. & Heisey, D.M. Vaginal mucosal immunization for recurrent urinary tract infection: Phase II clinical trial. J. Urol. 157, 2049-2052 (1997).
    • (1997) J. Urol. , vol.157 , pp. 2049-2052
    • Uehling, D.T.1    Hopkins, W.J.2    Balish, E.3    Xing, Y.4    Heisey, D.M.5
  • 126
    • 0035283055 scopus 로고    scopus 로고
    • Vaginal mucosal immunization for recurrent urinary tract infection: Extended phase II clinical trial
    • Uehling, D.T., Hopkins, W.J., Beierle, L.M., Kryger, J.V. & Heisey, D.M. Vaginal mucosal immunization for recurrent urinary tract infection: Extended phase II clinical trial. J. Infect. Dis. 183 (Suppl 1), S81-S83 (2001).
    • (2001) J. Infect. Dis. , vol.183 , Issue.SUPPL.1
    • Uehling, D.T.1    Hopkins, W.J.2    Beierle, L.M.3    Kryger, J.V.4    Heisey, D.M.5
  • 127
    • 76749170360 scopus 로고    scopus 로고
    • Waging war against uropathogenic Escherichia coli: Winning back the urinary tract
    • Sivick, K.E. & Mobley, H.L. Waging war against uropathogenic Escherichia coli: Winning back the urinary tract. Infect. Immun. 78, 568-585 (2009).
    • (2009) Infect. Immun. , vol.78 , pp. 568-585
    • Sivick, K.E.1    Mobley, H.L.2
  • 128
    • 67249094927 scopus 로고    scopus 로고
    • Bacteria-induced uroplakin signaling mediates bladder response to infection
    • Thumbikat, P. et al. Bacteria-induced uroplakin signaling mediates bladder response to infection. PLoS Pathog. 5, e1000415 (2009).
    • (2009) PLoS Pathog. , vol.5
    • Thumbikat, P.1
  • 129
    • 38549128203 scopus 로고    scopus 로고
    • Complicated catheter-Associated urinary tract infections due to Escherichia coli and Proteus mirabilis
    • Jacobsen, S.M., Stickler, D.J., Mobley, H.L. & Shirtliff, M.E. Complicated catheter-Associated urinary tract infections due to Escherichia coli and Proteus mirabilis. Clin. Microbiol. Rev. 21, 26-59 (2008).
    • (2008) Clin. Microbiol. Rev. , vol.21 , pp. 26-59
    • Jacobsen, S.M.1    Stickler, D.J.2    Mobley, H.L.3    Shirtliff, M.E.4
  • 130
    • 85185106527 scopus 로고    scopus 로고
    • No. 07-5512 (ed Public Health Service U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases) (U.S. Government Publishing Office, Washington DC
    • Litwin, M.S. & Saigal, C.S., (eds).Vol. NIH Publication No. 07-5512 (ed Public Health Service U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases) (U.S. Government Publishing Office, Washington DC, 2007).
    • (2007) NIH Publication
    • Litwin, M.S.1    Saigal, C.S.2
  • 131
    • 0037043290 scopus 로고    scopus 로고
    • Epidemiology of urinary tract infections: Incidence, morbidity, and economic costs
    • Foxman, B. Epidemiology of urinary tract infections: Incidence, morbidity, and economic costs. Am. J. Med. 113, 5S-13S (2002).
    • (2002) Am. J. Med. , vol.113
    • Foxman, B.1
  • 133
    • 33746770968 scopus 로고    scopus 로고
    • Bacterial interference-is deliberate colonization with Escherichia coli 83972 an alternative treatment for patients with recurrent urinary tract infectioñ Int
    • Sunden, F., Hakansson, L., Ljunggren, E. & Wullt, B. Bacterial interference-is deliberate colonization with Escherichia coli 83972 an alternative treatment for patients with recurrent urinary tract infectioñ Int. J. Antimicrob. Agents 28 (Suppl 1), S26-S29 (2006).
    • (2006) J. Antimicrob. Agents 28 (Suppl 1)
    • Sunden, F.1    Hakansson, L.2    Ljunggren, E.3    Wullt, B.4
  • 134
    • 0034200579 scopus 로고    scopus 로고
    • Bacterial interference for prevention of urinary tract infection: An overview
    • Darouiche, R.O. & Hull, R.A. Bacterial interference for prevention of urinary tract infection: An overview. J. Spinal Cord Med. 23, 136-141 (2000).
    • (2000) J. Spinal Cord Med. , vol.23 , pp. 136-141
    • Darouiche, R.O.1    Hull, R.A.2
  • 136
    • 0030747156 scopus 로고    scopus 로고
    • Detection, significance, and therapy of bacteriuria in pregnancy. Update in the managed health care era
    • Patterson, T.F. & Andriole, V.T. Detection, significance, and therapy of bacteriuria in pregnancy. Update in the managed health care era. Infect. Dis. Clin. North Am. 11, 593-608 (1997).
    • (1997) Infect. Dis. Clin. North Am. , vol.11 , pp. 593-608
    • Patterson, T.F.1    Andriole, V.T.2
  • 137
    • 33745245565 scopus 로고    scopus 로고
    • Asymptomatic bacteriuria Escherichia coli strain 83972 carries mutations in the foc locus and is unable to express F1C fimbriae
    • Roos, V., Schembri, M.A., Ulett, G.C. & Klemm, P. Asymptomatic bacteriuria Escherichia coli strain 83972 carries mutations in the foc locus and is unable to express F1C fimbriae. Microbiology 152, 1799-1806 (2006).
    • (2006) Microbiology , vol.152 , pp. 1799-1806
    • Roos, V.1    Schembri, M.A.2    Ulett, G.C.3    Klemm, P.4
  • 138
    • 33747045788 scopus 로고    scopus 로고
    • Asymptomatic bacteriuria Escherichia coli strains: Adhesins, growth and competition
    • Roos, V., Nielsen, E.M. & Klemm, P. Asymptomatic bacteriuria Escherichia coli strains: Adhesins, growth and competition. FEMS Microbiol. Lett. 262, 22-30 (2006).
    • (2006) FEMS Microbiol. Lett. , vol.262 , pp. 22-30
    • Roos, V.1    Nielsen, E.M.2    Klemm, P.3
  • 139
    • 84857165872 scopus 로고    scopus 로고
    • Comparison of asymptomatic bacteriuria Escherichia coli isolates from healthy individuals versus those from hospital patients shows that long-Term bladder colonization selects for attenuated virulence phenotypes
    • Salvador, E. et al. Comparison of asymptomatic bacteriuria Escherichia coli isolates from healthy individuals versus those from hospital patients shows that long-Term bladder colonization selects for attenuated virulence phenotypes. Infect. Immun. 80, 668-678 (2012).
    • (2012) Infect. Immun. , vol.80 , pp. 668-678
    • Salvador, E.1
  • 140
    • 84867605259 scopus 로고    scopus 로고
    • Identification of genes important for growth of asymptomatic bacteriuria Escherichia coli in urine
    • Vejborg, R.M. et al. Identification of genes important for growth of asymptomatic bacteriuria Escherichia coli in urine. Infect. Immun. 80, 3179-3188 (2012).
    • (2012) Infect. Immun. , vol.80 , pp. 3179-3188
    • Vejborg, R.M.1
  • 141
    • 0034609966 scopus 로고    scopus 로고
    • A prospective study of asymptomatic bacteriuria in sexually active young women
    • Hooton, T.M. et al. A prospective study of asymptomatic bacteriuria in sexually active young women. N. Engl. J. Med. 343, 992-997 (2000).
    • (2000) N. Engl. J. Med. , vol.343 , pp. 992-997
    • Hooton, T.M.1
  • 142
    • 84858706994 scopus 로고    scopus 로고
    • Predictive value of Escherichia coli susceptibility in strains causing asymptomatic bacteriuria for women with recurrent symptomatic urinary tract infections receiving prophylaxis
    • Beerepoot,M.A. et al. Predictive value of Escherichia coli susceptibility in strains causing asymptomatic bacteriuria for women with recurrent symptomatic urinary tract infections receiving prophylaxis. Clin. Microbiol. Infect. 18, E84-E90 (2012).
    • (2012) Clin. Microbiol. Infect. , vol.18
    • Beerepoot, M.A.1
  • 143
    • 84865462750 scopus 로고    scopus 로고
    • Editorial commentary: Asymptomatic bacteriuria-shift of paradigm
    • Wagenlehner, F.M.E. & Naber, K.G. Editorial commentary: Asymptomatic bacteriuria-shift of paradigm. Clin. Infect. Dis. 55, 778-780 (2012).
    • (2012) Clin. Infect. Dis. , vol.55 , pp. 778-780
    • Wagenlehner, F.M.E.1    Naber, K.G.2
  • 144
    • 84865460044 scopus 로고    scopus 로고
    • The role of asymptomatic bacteriuria in young women with recurrent urinary tract infections: To treat or not to treat?
    • Cai, T. et al. The role of asymptomatic bacteriuria in young women with recurrent urinary tract infections: To treat or not to treat? Clin. Infect. Dis. 55, 771-777 (2012).
    • (2012) Clin. Infect. Dis. , vol.55 , pp. 771-777
    • Cai, T.1
  • 145
    • 77953123716 scopus 로고    scopus 로고
    • Escherichia coli 83972 bacteriuria protects against recurrent lower urinary tract infections in patients with incomplete bladder emptying
    • Sunden, F., Hakansson, L., Ljunggren, E. & Wullt, B. Escherichia coli 83972 bacteriuria protects against recurrent lower urinary tract infections in patients with incomplete bladder emptying. J. Urol. 184, 179-185 (2010).
    • (2010) J. Urol. , vol.184 , pp. 179-185
    • Sunden, F.1    Hakansson, L.2    Ljunggren, E.3    Wullt, B.4
  • 146
    • 67651165094 scopus 로고    scopus 로고
    • Abacterial interference strategy for prevention ofUTI in persons practicing intermittent catheterization
    • Prasad, A., Cevallos, M.E., Riosa, S., Darouiche, R.O. & Trautner, B.W. Abacterial interference strategy for prevention ofUTI in persons practicing intermittent catheterization. Spinal Cord 47, 565-569 (2009).
    • (2009) Spinal Cord , vol.47 , pp. 565-569
    • Prasad, A.1    Cevallos, M.E.2    Riosa, S.3    Darouiche, R.O.4    Trautner, B.W.5
  • 147
    • 78449296237 scopus 로고    scopus 로고
    • Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors
    • Benson, A.K. et al. Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors. Proc. Natl. Acad. Sci. USA 107, 18933-18938 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 18933-18938
    • Benson, A.K.1
  • 148
    • 78149324553 scopus 로고    scopus 로고
    • Pathogen specific IRF3-dependent signaling and innate resistance to human kidney infection
    • Fischer, H. et al. Pathogen specific, IRF3-dependent signaling and innate resistance to human kidney infection. PLoS Pathog. 6, e1001109 (2010).
    • (2010) PLoS Pathog. , vol.6
    • Fischer, H.1
  • 149
    • 77949512726 scopus 로고    scopus 로고
    • Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women
    • Hawn, T.R. et al. Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women. PLoS One 4, e8300 (2009).
    • (2009) PLoS One , vol.4
    • Hawn, T.R.1
  • 150
    • 33846839659 scopus 로고    scopus 로고
    • Interleukin-8 and CXCR1 receptor functional polymorphisms and susceptibility to acute pyelonephritis
    • Artifoni, L. et al. Interleukin-8 and CXCR1 receptor functional polymorphisms and susceptibility to acute pyelonephritis. J. Urol. 177, 1102-1106 (2007).
    • (2007) J. Urol. , vol.177 , pp. 1102-1106
    • Artifoni, L.1
  • 151
    • 77958120655 scopus 로고    scopus 로고
    • Host imprints on bacterial genomes-rapid, divergent evolution in individual patients
    • Zdziarski, J. et al. Host imprints on bacterial genomes-rapid, divergent evolution in individual patients. PLoS Pathog. 6, e1001078 (2010).
    • (2010) PLoS Pathog. , vol.6
    • Zdziarski, J.1
  • 152
    • 82255195762 scopus 로고    scopus 로고
    • Genetic control of the variable innate immune response to asymptomatic bacteriuria
    • Hernandez, J.G., Sunden, F., Connolly, J., Svanborg, C. & Wullt, B. Genetic control of the variable innate immune response to asymptomatic bacteriuria. PLoS One 6, e28289 (2011).
    • (2011) PLoS One , vol.6
    • Hernandez, J.G.1    Sunden, F.2    Connolly, J.3    Svanborg, C.4    Wullt, B.5
  • 153
    • 33847638137 scopus 로고    scopus 로고
    • Estimates of the cancer incidence andmortality in Europe in 2006
    • Ferlay, J. et al. Estimates of the cancer incidence andmortality in Europe in 2006. Ann. Oncol. 18, 581-592 (2007).
    • (2007) Ann. Oncol. , vol.18 , pp. 581-592
    • Ferlay, J.1
  • 155
    • 0017130525 scopus 로고
    • Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors
    • Morales, A., Eidinger, D. & Bruce, A.W. Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors. J. Urol. 116, 180-183 (1976).
    • (1976) J. Urol. , vol.116 , pp. 180-183
    • Morales, A.1    Eidinger, D.2    Bruce, A.W.3
  • 156
    • 79955593955 scopus 로고    scopus 로고
    • EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder, the 2011 update
    • Babjuk, M. et al. EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder, the 2011 update. Eur. Urol. 59, 997-1008 (2011).
    • (2011) Eur. Urol. , vol.59 , pp. 997-1008
    • Babjuk, M.1
  • 157
    • 0026717957 scopus 로고
    • Intravesical Evans strainBCGtherapy: Quantitative immunohistochemical analysis of the immune response within the bladder wall
    • Prescott, S., James, K., Hargreave, T.B., Chisholm, G.D. & Smyth, J.F. Intravesical Evans strainBCGtherapy: Quantitative immunohistochemical analysis of the immune response within the bladder wall. J. Urol. 147, 1636-1642 (1992).
    • (1992) J. Urol. , vol.147 , pp. 1636-1642
    • Prescott, S.1    James, K.2    Hargreave, T.B.3    Chisholm, G.D.4    Smyth, J.F.5
  • 158
    • 0021874222 scopus 로고
    • Intravesical bacillus Calmette-Guerin therapy for superficial bladder cancer: Effect of bacillus Calmette-Guerin viability on treatment results
    • Kelley, D.R. et al. Intravesical bacillus Calmette-Guerin therapy for superficial bladder cancer: Effect of bacillus Calmette-Guerin viability on treatment results. J. Urol. 134, 48-53 (1985).
    • (1985) J. Urol. , vol.134 , pp. 48-53
    • Kelley, D.R.1
  • 159
    • 0023115081 scopus 로고
    • Intravesical Bacillus Calmette-Guerin therapy for murine bladder tumors: Initiation of the response by fibronectin-mediated attachment of Bacillus Calmette-Guerin
    • Ratliff, T.L., Palmer, J.O., McGarr, J.A. & Brown, E.J. Intravesical Bacillus Calmette-Guerin therapy for murine bladder tumors: Initiation of the response by fibronectin-mediated attachment of Bacillus Calmette-Guerin. Cancer Res. 47, 1762-1766 (1987).
    • (1987) Cancer Res. , vol.47 , pp. 1762-1766
    • Ratliff, T.L.1    Palmer, J.O.2    McGarr, J.A.3    Brown, E.J.4
  • 161
    • 0026597872 scopus 로고
    • Morphological aspects of the interaction of Bacillus Calmette-Guerin with urothelial bladder cells in vivo and in vitro: Relevance for antitumor activity?
    • Teppema, J.S., de Boer, E.C., Steerenberg, P.A. & van der Meijden, A.P. Morphological aspects of the interaction of Bacillus Calmette-Guerin with urothelial bladder cells in vivo and in vitro: Relevance for antitumor activity? Urol. Res. 20, 219-228 (1992).
    • (1992) Urol. Res. , vol.20 , pp. 219-228
    • Teppema, J.S.1    De Boer, E.C.2    Steerenberg, P.A.3    Van Der Meijden, A.P.4
  • 162
    • 0027534280 scopus 로고
    • Characterization of the internalization of bacillus Calmette-Guerin by human bladder tumor cells
    • Kuroda, K., Brown, E.J., Telle, W.B., Russell, D.G. & Ratliff, T.L. Characterization of the internalization of bacillus Calmette-Guerin by human bladder tumor cells. J. Clin. Invest. 91, 69-76 (1993).
    • (1993) J. Clin. Invest. , vol.91 , pp. 69-76
    • Kuroda, K.1    Brown, E.J.2    Telle, W.B.3    Russell, D.G.4    Ratliff, T.L.5
  • 163
    • 84873452824 scopus 로고    scopus 로고
    • Oncogenic activation of Pak1-dependent pathway of macropinocytosis determines BCG entry into bladder cancer cells
    • Redelman-Sidi, G., Iyer, G., Solit, D.B. & Glickman, M.S. Oncogenic activation of Pak1-dependent pathway of macropinocytosis determines BCG entry into bladder cancer cells. Cancer Res. 73, 1156-1167 (2013).
    • (2013) Cancer Res. , vol.73 , pp. 1156-1167
    • Redelman-Sidi, G.1    Iyer, G.2    Solit, D.B.3    Glickman, M.S.4
  • 164
    • 25444467767 scopus 로고    scopus 로고
    • Urothelial tumorigenesis: A tale of divergent pathways
    • Wu, X.R. Urothelial tumorigenesis: A tale of divergent pathways. Nat. Rev. Cancer 5, 713-725 (2005).
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 713-725
    • Wu, X.R.1
  • 165
    • 63049094489 scopus 로고    scopus 로고
    • Inactivation of p53 and Pten promotes invasive bladder cancer
    • Puzio-Kuter, A.M. et al. Inactivation of p53 and Pten promotes invasive bladder cancer. Genes Dev. 23, 675-680 (2009).
    • (2009) Genes Dev. , vol.23 , pp. 675-680
    • Puzio-Kuter, A.M.1
  • 166
    • 0025823180 scopus 로고
    • Internalization of bacille Calmette-Guerin by bladder tumor cells
    • Becich, M.J., Carroll, S. & Ratliff, T.L. Internalization of bacille Calmette-Guerin by bladder tumor cells. J. Urol. 145, 1316-1324 (1991).
    • (1991) J. Urol. , vol.145 , pp. 1316-1324
    • Becich, M.J.1    Carroll, S.2    Ratliff, T.L.3
  • 167
    • 77954980492 scopus 로고    scopus 로고
    • Recent advances in bacillus Calmette-Guerin immunotherapy in bladder cancer
    • Alexandroff, A.B., Nicholson, S., Patel, P.M. & Jackson, A.M. Recent advances in bacillus Calmette-Guerin immunotherapy in bladder cancer. Immunotherapy 2, 551-560 (2010).
    • (2010) Immunotherapy , vol.2 , pp. 551-560
    • Alexandroff, A.B.1    Nicholson, S.2    Patel, P.M.3    Jackson, A.M.4
  • 168
    • 34547612220 scopus 로고    scopus 로고
    • Thirty years of BCG immunotherapy for nonmuscle invasive bladder cancer: A success story with room for improvement
    • Brandau, S. & Suttmann, H. Thirty years of BCG immunotherapy for nonmuscle invasive bladder cancer: A success story with room for improvement. Biomed. Pharmacother. 61, 299-305 (2007).
    • (2007) Biomed. Pharmacother. , vol.61 , pp. 299-305
    • Brandau, S.1    Suttmann, H.2
  • 169
    • 0025776957 scopus 로고
    • Presence of activated lymphocytes in the urine of patients with superficial bladder cancer after intravesical immunotherapy with bacillus Calmette-Guerin
    • De Boer, E.C. et al. Presence of activated lymphocytes in the urine of patients with superficial bladder cancer after intravesical immunotherapy with bacillus Calmette-Guerin. Cancer Immunol. Immunother. 33, 411-416 (1991).
    • (1991) Cancer Immunol. Immunother. , vol.33 , pp. 411-416
    • De Boer, E.C.1
  • 170
    • 62049083648 scopus 로고    scopus 로고
    • Molecular analyte profiling of the early events and tissue conditioning following intravesical bacillus calmette-guerin therapy in patients with superficial bladder cancer
    • Bisiaux, A. et al. Molecular analyte profiling of the early events and tissue conditioning following intravesical bacillus calmette-guerin therapy in patients with superficial bladder cancer. J. Urol. 181, 1571-1580 (2009).
    • (2009) J. Urol. , vol.181 , pp. 1571-1580
    • Bisiaux, A.1
  • 171
    • 84862132424 scopus 로고    scopus 로고
    • Preexisting BCG-specific T cells improve intravesical immunotherapy for bladder cancer
    • 137ra172
    • Biot, C. et al. Preexisting BCG-specific T cells improve intravesical immunotherapy for bladder cancer. Sci. Transl. Med. 4, 137ra172 (2012).
    • (2012) Sci. Transl. Med. , vol.4
    • Biot, C.1
  • 172
    • 34250661461 scopus 로고    scopus 로고
    • Discriminators of mouse bladder response to intravesical Bacillus Calmette-Guerin (BCG)
    • Saban, M.R. et al. Discriminators of mouse bladder response to intravesical Bacillus Calmette-Guerin (BCG). BMC Immunol. 8, 6 (2007).
    • (2007) BMC Immunol. , vol.8 , pp. 6
    • Saban, M.R.1
  • 173
    • 0028915845 scopus 로고
    • Changes in urinary cytokines and soluble intercellular adhesion molecule-1 (ICAM-1) in bladder cancer patients after bacillus Calmette-Guerin (BCG) immunotherapy
    • Jackson, A.M. et al. Changes in urinary cytokines and soluble intercellular adhesion molecule-1 (ICAM-1) in bladder cancer patients after bacillus Calmette-Guerin (BCG) immunotherapy. Clin. Exp. Immunol. 99, 369-375 (1995).
    • (1995) Clin. Exp. Immunol. , vol.99 , pp. 369-375
    • Jackson, A.M.1
  • 174
    • 45849112914 scopus 로고    scopus 로고
    • Role of neutrophils in BCG immunotherapy for bladder cancer
    • Simons, M.P., O'Donnell, M.A. & Griffith, T.S. Role of neutrophils in BCG immunotherapy for bladder cancer. Urol. Oncol. 26, 341-345 (2008).
    • (2008) Urol. Oncol. , vol.26 , pp. 341-345
    • Simons, M.P.1    O'Donnell, M.A.2    Griffith, T.S.3
  • 175
    • 0033938697 scopus 로고    scopus 로고
    • Prognostic value of tumor-Associated macrophage count in human bladder cancer
    • Hanada, T. et al. Prognostic value of tumor-Associated macrophage count in human bladder cancer. Int. J. Urol. 7, 263-269 (2000).
    • (2000) Int. J. Urol. , vol.7 , pp. 263-269
    • Hanada, T.1
  • 176
    • 61949486981 scopus 로고    scopus 로고
    • Increased infiltration of tumor associated macrophages is associated with poor prognosis of bladder carcinoma in situ after intravesical bacillus Calmette-Guerin instillation
    • Takayama, H. et al. Increased infiltration of tumor associated macrophages is associated with poor prognosis of bladder carcinoma in situ after intravesical bacillus Calmette-Guerin instillation. J. Urol. 181, 1894-1900 (2009).
    • (2009) J. Urol. , vol.181 , pp. 1894-1900
    • Takayama, H.1
  • 177
    • 65049091771 scopus 로고    scopus 로고
    • Bladder tumor infiltrating mature dendritic cells and macrophages as predictors of response to bacillus Calmette-Guerin immunotherapy
    • Ayari, C. et al. Bladder tumor infiltrating mature dendritic cells and macrophages as predictors of response to bacillus Calmette-Guerin immunotherapy. Eur. Urol. 55, 1386-1395 (2009).
    • (2009) Eur. Urol. , vol.55 , pp. 1386-1395
    • Ayari, C.1
  • 178
    • 0023193318 scopus 로고
    • Requirement of a thymus dependent immune response for BCG-mediated antitumor activity
    • Ratliff, T.L., Gillen, D. & Catalona, W.J. Requirement of a thymus dependent immune response for BCG-mediated antitumor activity. J. Urol. 137, 155-158 (1987).
    • (1987) J. Urol. , vol.137 , pp. 155-158
    • Ratliff, T.L.1    Gillen, D.2    Catalona, W.J.3
  • 179
    • 0027179385 scopus 로고
    • T-cell subsets required for intravesical BCG immunotherapy for bladder cancer
    • Ratliff, T.L., Ritchey, J.K., Yuan, J.J., Andriole, G.L. Catalona,W.J. T-cell subsets required for intravesical BCG immunotherapy for bladder cancer. J. Urol. 150, 1018-1023 (1993).
    • (1993) J. Urol. , vol.150 , pp. 1018-1023
    • Ratliff, T.L.1    Ritchey, J.K.2    Yuan, J.J.3    Andriole, G.L.4    Catalona, W.J.5
  • 180
    • 0035371645 scopus 로고    scopus 로고
    • NK cells are essential for effectiveBCGimmunotherapy
    • Brandau, S. et al. NK cells are essential for effectiveBCGimmunotherapy. Int. J. Cancer 92, 697-702 (2001).
    • (2001) Int. J. Cancer , vol.92 , pp. 697-702
    • Brandau, S.1
  • 181
    • 33748085674 scopus 로고    scopus 로고
    • Neutrophil granulocytes are required for effective Bacillus Calmette-Guerin immunotherapy of bladder cancer and orchestrate local immune responses
    • Suttmann, H. et al. Neutrophil granulocytes are required for effective Bacillus Calmette-Guerin immunotherapy of bladder cancer and orchestrate local immune responses. Cancer Res. 66, 8250-8257 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 8250-8257
    • Suttmann, H.1
  • 182
    • 0141988849 scopus 로고    scopus 로고
    • Cytokine gene expression in a mouse model: The first instillations with viable bacillus Calmette-Guerin determine the succeeding Th1 response
    • De Boer, E.C., Rooijakkers, S.J., Schamhart, D.H. & Kurth, K.H. Cytokine gene expression in a mouse model: The first instillations with viable bacillus Calmette-Guerin determine the succeeding Th1 response. J. Urol. 170, 2004-2008 (2003).
    • (2003) J. Urol. , vol.170 , pp. 2004-2008
    • De Boer, E.C.1    Rooijakkers, S.J.2    Schamhart, D.H.3    Kurth, K.H.4
  • 183
    • 0037318434 scopus 로고    scopus 로고
    • Interleukin 10 induced augmentation of delayed-Type hypersensitivity (DTH) enhances Mycobacterium bovis bacillus Calmette-Guerin (BCG) mediated antitumour activity
    • Nadler, R. et al. Interleukin 10 induced augmentation of delayed-Type hypersensitivity (DTH) enhances Mycobacterium bovis bacillus Calmette-Guerin (BCG) mediated antitumour activity. Clin. Exp. Immunol. 131, 206-216 (2003).
    • (2003) Clin. Exp. Immunol. , vol.131 , pp. 206-216
    • Nadler, R.1
  • 184
    • 0027984008 scopus 로고
    • Induction of TH1- And TH2-Associated cytokine mRNA in mouse bladder
    • McAveney, K.M., Gomella, L.G. & Lattime, E.C. Induction of TH1- And TH2-Associated cytokine mRNA in mouse bladder following intravesical growth of the murine bladder tumor MB49 and BCG immunotherapy. Cancer Immunol. Immunother. 39, 401-406 (1994).
    • (1994) Cancer Immunol. Immunother. , vol.39 , pp. 401-406
    • McAveney, K.M.1    Gomella, L.G.2    Lattime, E.C.3
  • 185
    • 0036177621 scopus 로고    scopus 로고
    • IFN-gamma and IL-12 but not IL-10 are required for local tumour surveillance in a syngeneic model of orthotopic bladder cancer
    • Riemensberger, J., Bohle, A. & Brandau, S. IFN-gamma and IL-12 but not IL-10 are required for local tumour surveillance in a syngeneic model of orthotopic bladder cancer. Clin. Exp. Immunol. 127, 20-26 (2002).
    • (2002) Clin. Exp. Immunol. , vol.127 , pp. 20-26
    • Riemensberger, J.1    Bohle, A.2    Brandau, S.3
  • 186
    • 84861093442 scopus 로고    scopus 로고
    • Anti-interleukin-10R1 monoclonal antibody enhances bacillus Calmette-Guerin induced T-helper type 1 immune responses and antitumor immunity in a mouse orthotopic model of bladder cancer
    • Bockholt, N.A. et al. Anti-interleukin-10R1 monoclonal antibody enhances bacillus Calmette-Guerin induced T-helper type 1 immune responses and antitumor immunity in a mouse orthotopic model of bladder cancer. J. Urol. 187, 2228-2235 (2012).
    • (2012) J. Urol. , vol.187 , pp. 2228-2235
    • Bockholt, N.A.1
  • 187
    • 0036135232 scopus 로고    scopus 로고
    • Prognostic value of a T helper 1 urinary cytokine response after intravesical bacillus Calmette-Guerin treatment for superficial bladder cancer
    • Saint, F. et al. Prognostic value of a T helper 1 urinary cytokine response after intravesical bacillus Calmette-Guerin treatment for superficial bladder cancer. J. Urol. 167, 364-367 (2002).
    • (2002) J. Urol. , vol.167 , pp. 364-367
    • Saint, F.1
  • 188
    • 82255192477 scopus 로고    scopus 로고
    • Markers predicting response to bacillus Calmette-Guerin immunotherapy in high-risk bladder cancer patients: A systematic review
    • Zuiverloon, T.C. et al. Markers predicting response to bacillus Calmette-Guerin immunotherapy in high-risk bladder cancer patients: A systematic review. Eur. Urol. 61, 128-145 (2012).
    • (2012) Eur. Urol. , vol.61 , pp. 128-145
    • Zuiverloon, T.C.1
  • 189
    • 0142090687 scopus 로고    scopus 로고
    • Urinary IL-2 assay for monitoring intravesical bacillus Calmette-Guerin response of superficial bladder cancer during induction course and maintenance therapy
    • Saint, F. et al. Urinary IL-2 assay for monitoring intravesical bacillus Calmette-Guerin response of superficial bladder cancer during induction course and maintenance therapy. Int. J. Cancer 107, 434-440 (2003).
    • (2003) Int. J. Cancer , vol.107 , pp. 434-440
    • Saint, F.1
  • 190
    • 0041903671 scopus 로고    scopus 로고
    • Urinary interleukin-2 may predict clinical outcome of intravesical bacillus Calmette-Guerin immunotherapy for carcinoma in situ of the bladder
    • Watanabe, E. et al. Urinary interleukin-2 may predict clinical outcome of intravesical bacillus Calmette-Guerin immunotherapy for carcinoma in situ of the bladder. Cancer Immunol. Immunother. 52, 481-486 (2003).
    • (2003) Cancer Immunol. Immunother. , vol.52 , pp. 481-486
    • Watanabe, E.1
  • 191
    • 0030051368 scopus 로고    scopus 로고
    • Urinary cytokines during intravesical bacillus Calmette-Guerin therapy for superficial bladder cancer: Processing, stability and prognostic value
    • de Reijke, T.M., de Boer, E.C., Kurth, K.H. & Schamhart, D.H. Urinary cytokines during intravesical bacillus Calmette-Guerin therapy for superficial bladder cancer: Processing, stability and prognostic value. J. Urol. 155, 477-482 (1996).
    • (1996) J. Urol. , vol.155 , pp. 477-482
    • De Reijke, T.M.1    De Boer, E.C.2    Kurth, K.H.3    Schamhart, D.H.4
  • 192
    • 78650253128 scopus 로고    scopus 로고
    • Stress proteins and cytokines are urinary biomarkers for diagnosis and staging of bladder cancer
    • Margel, D., Pevsner-Fischer, M., Baniel, J., Yossepowitch, O. & Cohen, I.R. Stress proteins and cytokines are urinary biomarkers for diagnosis and staging of bladder cancer. Eur. Urol. 59, 113-119 (2011).
    • (2011) Eur. Urol. , vol.59 , pp. 113-119
    • Margel, D.1    Pevsner-Fischer, M.2    Baniel, J.3    Yossepowitch, O.4    Cohen, I.R.5
  • 194
    • 84867633653 scopus 로고    scopus 로고
    • The role of chemokine and chemokine receptor gene variants on the susceptibility and clinicopathological characteristics of bladder cancer
    • Kucukgergin, C. et al. The role of chemokine and chemokine receptor gene variants on the susceptibility and clinicopathological characteristics of bladder cancer. Gene 511, 7-11 (2012).
    • (2012) Gene , vol.511 , pp. 7-11
    • Kucukgergin, C.1
  • 195
    • 84875382601 scopus 로고    scopus 로고
    • Association of IL-12, IL-18 variants and serum IL-18 with bladder cancer susceptibility in North Indian population
    • Jaiswal, P.K., Singh, V., Srivastava, P. & Mittal, R.D. Association of IL-12, IL-18 variants and serum IL-18 with bladder cancer susceptibility in North Indian population. Gene 519, 128-134 (2013).
    • (2013) Gene , vol.519 , pp. 128-134
    • Jaiswal, P.K.1    Singh, V.2    Srivastava, P.3    Mittal, R.D.4
  • 196
    • 33749239193 scopus 로고    scopus 로고
    • Cytokine gene polymorphisms can alter the effect of bacillus calmette-guerin (bcg) immunotherapy
    • Basturk, B., Yavascaoglu, I., Oral, B.,Goral, G. Oktay, B. Cytokine gene polymorphisms can alter the effect of Bacillus Calmette-Guerin (BCG) immunotherapy. Cytokine 35, 1-5 (2006).
    • (2006) Cytokine , vol.35 , pp. 1-5
    • Basturk, B.1    Yavascaoglu, I.2    Oral, B.3    Goral, G.4    Oktay, B.5
  • 197
    • 0031595289 scopus 로고    scopus 로고
    • Bacille Calmette-Guerin in superficial transitional cell carcinoma
    • Mungan, N.A. & Witjes, J.A. Bacille Calmette-Guerin in superficial transitional cell carcinoma. Br. J. Urol. 82, 213-223 (1998).
    • (1998) Br. J. Urol. , vol.82 , pp. 213-223
    • Mungan, N.A.1    Witjes, J.A.2
  • 198
    • 79953087989 scopus 로고    scopus 로고
    • Effects of intravesical liposome-mediated human beta-defensin-2 gene transfection in a mouse urinary tract infection model
    • Zhao, J., Wang, Z., Chen, X., Wang, J. & Li, J. Effects of intravesical liposome-mediated human beta-defensin-2 gene transfection in a mouse urinary tract infection model. Microbiol. Immunol. 55, 217-223 (2011).
    • (2011) Microbiol. Immunol. , vol.55 , pp. 217-223
    • Zhao, J.1    Wang, Z.2    Chen, X.3    Wang, J.4    Li, J.5
  • 199
    • 81455128775 scopus 로고    scopus 로고
    • Treatment and prevention of urinary tract infection with orally active FimH inhibitors
    • 109ra115
    • Cusumano, C.K. et al. Treatment and prevention of urinary tract infection with orally active FimH inhibitors. Sci. Transl. Med. 3, 109ra115 (2011).
    • (2011) Sci. Transl. Med. , vol.3
    • Cusumano, C.K.1
  • 200
    • 34249670657 scopus 로고    scopus 로고
    • Cyclic AMP-regulated exocytosis of Escherichia coli from infected bladder epithelial cells
    • Bishop, B.L. et al. Cyclic AMP-regulated exocytosis of Escherichia coli from infected bladder epithelial cells. Nat. Med. 13, 625-630 (2007).
    • (2007) Nat. Med. , vol.13 , pp. 625-630
    • Bishop, B.L.1
  • 201
    • 67650886048 scopus 로고    scopus 로고
    • In vitro and in vivo effects of CpG-Oligodeoxynucleotides (CpG-ODN) on murine transitional cell carcinoma and on the native murine urinary bladder wall
    • Olbert, P.J. et al. In vitro and in vivo effects of CpG- Oligodeoxynucleotides (CpG-ODN) on murine transitional cell carcinoma and on the native murine urinary bladder wall. Anticancer Res. 29, 2067-2076 (2009).
    • (2009) Anticancer Res. , vol.29 , pp. 2067-2076
    • Olbert, P.J.1
  • 202
    • 84879690430 scopus 로고    scopus 로고
    • A molecular complex of bovine milk protein and oleic acid selectively kills cancer cells in vitro and inhibits tumour growth in an orthotopic rat bladder tumour model
    • Xiao, Z., Mak, A., Koch, K. & Moore, R.B. A molecular complex of bovine milk protein and oleic acid selectively kills cancer cells in vitro and inhibits tumour growth in an orthotopic rat bladder tumour model. BJU Int. 112, E201-E210 (2013).
    • (2013) BJU Int. , vol.112
    • Xiao, Z.1    Mak, A.2    Koch, K.3    Moore, R.B.4
  • 203
    • 0032844738 scopus 로고    scopus 로고
    • Role of IL-12 in the induction and potentiation of IFN-gamma in response to bacillus Calmette-Guerin
    • O'Donnell, M.A. et al. Role of IL-12 in the induction and potentiation of IFN-gamma in response to bacillus Calmette-Guerin. J. Immunol. 163, 4246-4252 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 4246-4252
    • O'Donnell, M.A.1
  • 204
    • 0033557730 scopus 로고    scopus 로고
    • IFNalpha 2B enhances Th1 cytokine responses in bladder cancer patients receiving Mycobacterium bovis bacillus Calmette-Guerin immunotherapy
    • Luo, Y., Chen, X., Downs, T.M., DeWolf, W.C. & O'Donnell, M.A. IFNalpha 2B enhances Th1 cytokine responses in bladder cancer patients receiving Mycobacterium bovis bacillus Calmette-Guerin immunotherapy. J. Immunol. 162, 2399-2405 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 2399-2405
    • Luo, Y.1    Chen, X.2    Downs, T.M.3    DeWolf, W.C.4    O'Donnell, M.A.5
  • 205
    • 0033166395 scopus 로고    scopus 로고
    • Antitumour immunity of Bacillus Calmette-Guerin and interferon alpha in murine bladder cancer
    • Gan, Y.H., Zhang, Y., Khoo, H.E. & Esuvaranathan, K. Antitumour immunity of Bacillus Calmette-Guerin and interferon alpha in murine bladder cancer. Eur. J. Cancer 35, 1123-1129 (1999).
    • (1999) Eur. J. Cancer , vol.35 , pp. 1123-1129
    • Gan, Y.H.1    Zhang, Y.2    Khoo, H.E.3    Esuvaranathan, K.4
  • 206
    • 85185101132 scopus 로고    scopus 로고
    • Bacillus Calmette-Guerin plus intravesical interferon alpha-2b in patients with superficial bladder cancer
    • 957-961. discussion
    • Stricker, P. et al. Bacillus Calmette-Guerin plus intravesical interferon alpha-2b in patients with superficial bladder cancer. Urology 48, 957-961. discussion 961-952 (1996).
    • (1996) Urology , vol.48 , pp. 961-952
    • Stricker, P.1
  • 207
    • 77957852856 scopus 로고    scopus 로고
    • Bacillus Calmette-Guerin with or without interferon alpha-2b and megadose versus recommended daily allowance vitamins during induction and maintenance intravesical treatment of nonmuscle invasive bladder cancer
    • Nepple, K.G., Lightfoot, A.J., Rosevear, H.M., O'Donnell, M.A. & Lamm, D.L. Bacillus Calmette-Guerin with or without interferon alpha-2b and megadose versus recommended daily allowance vitamins during induction and maintenance intravesical treatment of nonmuscle invasive bladder cancer. J. Urol. 184, 1915-1919 (2010).
    • (2010) J. Urol. , vol.184 , pp. 1915-1919
    • Nepple, K.G.1    Lightfoot, A.J.2    Rosevear, H.M.3    O'Donnell, M.A.4    Lamm, D.L.5
  • 208
    • 81555227857 scopus 로고    scopus 로고
    • Th1 cytokine-secreting recombinantMycobacterium bovis bacillus Calmette-Guerin and prospective use in immunotherapy of bladder cancer
    • Luo, Y., Henning, J. & O'Donnell, M.A. Th1 cytokine-secreting recombinantMycobacterium bovis bacillus Calmette-Guerin and prospective use in immunotherapy of bladder cancer. Clin. Dev. Immunol. 2011, 728930 (2011).
    • (2011) Clin. Dev. Immunol. , vol.2011 , pp. 728930
    • Luo, Y.1    Henning, J.2    O'Donnell, M.A.3
  • 209
    • 0035119134 scopus 로고    scopus 로고
    • Recombinant Bacille Calmette-Guerin (BCG) expressing human interferon-Alpha 2B demonstrates enhanced immunogenicity
    • Luo, Y., Chen, X., Han, R. & O'Donnell, M.A. Recombinant Bacille Calmette-Guerin (BCG) expressing human interferon-Alpha 2B demonstrates enhanced immunogenicity. Clin. Exp. Immunol. 123, 264-270 (2001).
    • (2001) Clin. Exp. Immunol. , vol.123 , pp. 264-270
    • Luo, Y.1    Chen, X.2    Han, R.3    O'Donnell, M.A.4
  • 210
    • 68549123471 scopus 로고    scopus 로고
    • Recombinant bacillus Calmette-Guerin (BCG) expressing interferon-Alpha 2B enhances human mononuclear cell cytotoxicity against bladder cancer cell lines in vitro
    • Liu, W., O'Donnell, M.A., Chen, X., Han, R. & Luo, Y. Recombinant bacillus Calmette-Guerin (BCG) expressing interferon-Alpha 2B enhances human mononuclear cell cytotoxicity against bladder cancer cell lines in vitro. Cancer Immunol. Immunother. 58, 1647-1655 (2009).
    • (2009) Cancer Immunol. Immunother. , vol.58 , pp. 1647-1655
    • Liu, W.1    O'Donnell, M.A.2    Chen, X.3    Han, R.4    Luo, Y.5
  • 211
    • 22344433382 scopus 로고    scopus 로고
    • Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin
    • Grode, L. et al. Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin. J. Clin. Invest. 115, 2472-2479 (2005).
    • (2005) J. Clin. Invest. , vol.115 , pp. 2472-2479
    • Grode, L.1
  • 212
    • 0019402424 scopus 로고
    • BCG immunotherapy of bladder cancer: Inhibition of tumor recurrence and associated immune responses
    • Lamm, D.L., Thor,D.E.,Winters,W.D., Stogdill, V.D. & Radwin, H.M.BCG immunotherapy of bladder cancer: Inhibition of tumor recurrence and associated immune responses. Cancer 48, 82-88 (1981).
    • (1981) Cancer , vol.48 , pp. 82-88
    • Lamm, D.L.1    Thor, D.E.2    Winters, W.D.3    Stogdill, V.D.4    Radwin, H.M.5


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