Anti-interleukin-10R1 monoclonal antibody enhances bacillus Calmette-Guérin induced T-helper type 1 immune responses and antitumor immunity in a mouse orthotopic model of bladder cancer

Journal of Urology

Volumn 187, Issue 6, 2012, Pages 2228-2235

  Bockholt, Nathan A ^a   Knudson, Matthew J ^a   Henning, Jonathan R ^a   Maymí, José L ^a   Weady, Peter ^a,b   Smith III, George J ^a,b   Eisenbraun, Michael D ^a,b   Fraser, James D ^a,b   O'Donnell, Michael A ^a   Luo, Yi ^a  

^a UNIVERSITY OF IOWA   (United States)

^b PFIZER INC   (United States)

Author keywords

BCG vaccine; interleukin 10 receptor alpha subunit; mice; urinary bladder; urinary bladder neoplasms

Indexed keywords

BCG VACCINE; EOTAXIN; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANZYME B; IMMUNOGLOBULIN G1; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 10 RECEPTOR 1; INTERLEUKIN 10 RECEPTOR 1 MONOCLONAL ANTIBODY; INTERLEUKIN 12P35; MESSENGER RNA; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; PERFORIN; PHOSPHATE BUFFERED SALINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; BLADDER CANCER; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEATH; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SPLEEN CELL; TH1 CELL; TUMOR IMMUNITY; URINE;

ANIMALS; ANTIBODIES, MONOCLONAL; CARCINOMA, TRANSITIONAL CELL; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; FEMALE; IMMUNOTHERAPY; INTERLEUKIN-10 RECEPTOR ALPHA SUBUNIT; MICE; MICE, INBRED C57BL; MYCOBACTERIUM BOVIS; TH1 CELLS; URINARY BLADDER NEOPLASMS;

EID: 84861093442     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2012.01.030     Document Type: Article

References (25)

1. S.K. Williams, D.M. Hoenig, R. Ghavamian Intravesical therapy for bladder cancer Expert Opin Pharmacother 11 2010 947
2. S. Brandau, H. Suttmann Thirty years of BCG immunotherapy for non-muscle invasive bladder cancer: a success story with room for improvement Biomed Pharmacother 61 2007 299
3. T.M. De Reijke, E.C. De Boer, K.H. Kurth Urinary cytokines during intravesical bacillus Calmette-Guerin therapy for superficial bladder cancer: processing, stability and prognostic value J Urol 155 1996 477
4. F. Saint, J.J. Patard, P. Maille Prognostic value of a T helper 1 urinary cytokine response after intravesical bacillus Calmette-Guerin treatment for superficial bladder cancer J Urol 167 2002 364
5. R. Nadler, Y. Luo, W. Zhao Interleukin 10 induced augmentation of delayed-type hypersensitivity (DTH) enhances Mycobacterium bovis bacillus Calmette-Guérin (BCG) mediated antitumour activity Clin Exp Immunol 131 2003 206
6. J. Riemensberger, A. Böhle, S. Brandau IFN-gamma and IL-12 but not IL-10 are required for local tumour surveillance in a syngeneic model of orthotopic bladder cancer Clin Exp Immunol 127 2002 20
7. K.W. Moore, R. de Waal Malefyt, R.L. Coffman Interleukin-10 and the interleukin-10 receptor Annu Rev Immunol 19 2001 683
8. Z. Qin, G. Noffz, M. Mohaupt Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells J Immunol 159 1997 770
9. G. Richter, S. Krüger-Krasagakes, G. Hein Interleukin 10 transfected into Chinese hamster ovary cells prevents tumor growth and macrophage infiltration Cancer Res 53 1993 4134
10. R. de Waal Malefyt, J. Haanen, H. Spits Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression J Exp Med 174 1991 915
11. L. Ding, P.S. Linsley, L.Y. Huang IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression J Immunol 151 1993 1224
12. F. Willems, A. Marchant, J.P. Delville Interleukin-10 inhibits B7 and intercellular adhesion molecule-1 expression on human monocytes Eur J Immunol 24 1994 1007
13. K. Steinbrink, M. Wölfl, H. Jonuleit Induction of tolerance by IL-10-treated dendritic cells J Immunol 159 1997 4772
14. H. Groux, A. O'Garra, M. Bigler A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis Nature 389 1997 737
15. D.F. Fiorentino, A. Zlotnik, T.R. Mosmann IL-10 inhibits cytokine production by activated macrophages J Immunol 147 1991 3815
16. E. Cenci, L. Romani, A. Mencacci Interleukin-4 and interleukin-10 inhibit nitric oxide-dependent macrophage killing of Candida albicans Eur J Immunol 23 1993 1034
17. C. Bogdan, Y. Vodovotz, C. Nathan Macrophage deactivation by interleukin 10 J Exp Med 174 1991 1549
18. Y. Luo, X. Chen, M.A. O'Donnell Use of prostate specific antigen to measure bladder tumor growth in a mouse orthotopic model J Urol 172 2004 2414
19. Y. Luo, X. Chen, M.A. O'Donnell Role of Th1 and Th2 cytokines in BCG-induced IFN-gamma production: cytokine promotion and simulation of BCG effect Cytokine 21 2003 17
20. R. Kim, W. Liu, X. Chen Intravesical dimethyl sulfoxide inhibits acute and chronic bladder inflammation in transgenic experimental autoimmune cystitis models J Biomed Biotechnol 2011 2011 937061
21. M.A. O'Donnell, Y. Luo, S.E. Hunter Interleukin-12 immunotherapy of murine transitional cell carcinoma of the bladder: dose dependent tumor eradication and generation of protective immunity J Urol 171 2004 1330
22. A. Jurczok, P. Fornara, A. Söling Bioluminescence imaging to monitor bladder cancer cell adhesion in vivo: a new approach to optimize a syngeneic, orthotopic, murine bladder cancer model BJU Int 101 2008 120
23. D.A. Zaharoff, B.S. Hoffman, H.B. Hooper Intravesical immunotherapy of superficial bladder cancer with chitosan/interleukin-12 Cancer Res 69 2009 6192
24. S.M. Mangsbo, C. Ninalga, M. Essand CpG therapy is superior to BCG in an orthotopic bladder cancer model and generates CD4+ T-cell immunity J Immunother 31 2008 34
25. M.R. Saban, C. Simpson, C. Davis Discriminators of mouse bladder response to intravesical bacillus Calmette-Guerin (BCG) BMC Immunol 8 2007 6