Hypothermic oxygenated perfusion (HOPE) protects from biliary injury in a rodent model of DCD liver transplantation

Journal of Hepatology

Volumn 59, Issue 5, 2013, Pages 984-991

  Schlegel, Andrea ^b   Graf, Rolf ^b   Clavien, Pierre Alain ^b   Dutkowski, Philipp ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b NONE

Author keywords

Biliary injury; DCD liver; Hypothermic oxygenated perfusion; Immune response; Liver transplantation

Indexed keywords

BILIRUBIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILIARY TRACT DISEASE; CELL ACTIVATION; CHOLESTASIS; CONTROLLED STUDY; CRYOPRESERVATION; DONOR; ENDOTHELIUM CELL; FIBROSIS; HEART ARREST; HYPOTHERMIC OXYGENATED PERFUSION; IMPLANTATION; ISCHEMIA; KUPFFER CELL; LIVER; LIVER CELL DAMAGE; LIVER GRAFT; LIVER TRANSPLANTATION; MALE; NONHUMAN; OUTCOME ASSESSMENT; PERFUSION; PORTAL VEIN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; RODENT MODEL; WEIGHT GAIN;

8-HYDROXYDESOXY-GUANOSIN; 8-OHDG; ALPHA SMOOTH MUSCLE ACTIN; BILIARY INJURY; CD154; CD28; CD40; CD68; CD80; CLUSTER OF DIFFERENTIATION 40; CLUSTER OF DIFFERENTIATION 68; CLUSTER OF DIFFERENTIATION 80; CO-STIMULATORY PROTEIN 28; CO-STIMULATORY PROTEIN 40 LIGAND; DAMAGE ASSOCIATED MOLECULAR PATTERN SIGNALLING; DAMPS; DCD; DCD LIVER; DONATION AFTER CARDIAC DEATH; ELISA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FACS; FLUORESCENCE-ACTIVATED CELL SORTING; H&E; HAEMATOXYLIN AND EOSIN; HIGH MOBILITY GROUP BOX-1 PROTEIN; HMGB1; HOPE; HYPOTHERMIC OXYGENATED PERFUSION; IC; IL-17; IL-2; IMMUNE RESPONSE; INTERLEUKIN-17; INTERLEUKIN-2; ISCHEMIC CHOLANGIOPATHY; LIVER TRANSPLANTATION; MITOCHONDRIAL PERMEABILITY PORE; MPT; REACTIVE OXYGEN SPECIES; ROS; SECS; SINUSOIDAL ENDOTHELIAL CELLS; TERMINAL DEOXYNUCLEOTIDYLTRANSFERASE ASSAY; TLR-4; TNF-Α; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; TUNEL; Α-SMA;

ANIMALS; BILIARY TRACT; COLD TEMPERATURE; DISEASE MODELS, ANIMAL; GRAFT SURVIVAL; HEART ARREST; HEPATOCYTES; KUPFFER CELLS; LIVER TRANSPLANTATION; MALE; ORGAN PRESERVATION; OXYGEN; PERFUSION; RATS; RATS, INBRED BN; REPERFUSION INJURY; TISSUE AND ORGAN PROCUREMENT; TREATMENT OUTCOME; WARM ISCHEMIA;

EID: 84885956679     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.06.022     Document Type: Article

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