Early down regulation of the glial Kir4.1 and GLT-1 expression in pericontusional cortex of the old male mice subjected to traumatic brain injury

Biogerontology

Volumn 14, Issue 5, 2013, Pages 531-541

  Gupta, R K ^a   Prasad, S ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

Aging; Glia; Glutamate and K+ homeostasis. GLT 1 EAAT2. Kir4.1; Traumatic brain injury (TBI)

Indexed keywords

INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR4.1; MESSENGER RNA; SODIUM GLUCOSE COTRANSPORTER 1; UNCLASSIFIED DRUG;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN FUNCTION; CONTROLLED STUDY; DEPOLARIZATION; DOWN REGULATION; EXCITOTOXICITY; GENE EXPRESSION; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; PERICONTUSIONAL CORTEX; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNAPSE; TRAUMATIC BRAIN INJURY; WESTERN BLOTTING;

AGING; ANIMALS; BASE SEQUENCE; BRAIN INJURIES; CEREBRAL CORTEX; DNA PRIMERS; DOWN-REGULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EXCITATORY AMINO ACID TRANSPORTER 2; MALE; MICE; NEUROGLIA; POTASSIUM CHANNELS, INWARDLY RECTIFYING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84885955521     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-013-9459-y     Document Type: Article

References (57)

1. Anderson JR, Hamilton ES, Berman NEJ (2009) Impaired expression of neuro-protective molecules in the HIF-1 α pathway following traumatic brain injury in aged mice. J Neurotrauma 26:1557-1566
2. Barreto GE, Gonzalez J, Torres Y, Morales L (2011) Astrocytic-neuronal crosstalk: implications for neuroprotection from brain injury. Neurosci Res 71:107-113
3. Bordey A, Sontheimer H (1998) Properties of human glial cells associated with epileptic seizure foci. Epilepsy Res 32:286-303
4. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
5. Buga AM, Dunoiu C, Balseanu A, Popa-Wagner A (2008) Cellular and molecular mechanisms underlying neurorehabilitation after stroke in aged subjects. Rom J Morphol Embryol 49(3):279-302
6. Butt AM, Kalsi A (2006) Inwardly rectifying potassium channels (Kir) in central nervous system glia: a special role for Kir4.1 in glial functions. J Cell Mol Med 10:33-44
7. Cekic M, Stein D (2010) Traumatic brain injury and aging: is a combination of progesterone and vitamin D hormone a simple solution to a complex problem. Neurotherapeutics 7:81-90
8. Chen Y, Swanson RA (2003) Astrocytes and Brain Injury. J Cereb Blood Flow Metab 23:137-149
9. Cortez SC, McIntosh TK, Noble LJ (1989) Experimental fluid percussion brain injury: vascular disruption and neuronal and glial alterations. Brain Res 482:271-282
10. Dhillon HS, Dose JM, Scheff SW, Prasad MR (1997) Time course of changes in lactate and free fatty acids after experimental brain injury and relationship to morphologic damage. Exp Neurol 146:240-249
11. Djukic B, Casper KB, Philpot BD, Chin LS, McCarthy KD (2007) Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation. J Neurosci 27:11354-11365
12. Fineman I, Hovda DA, Smith M, Yoshino A, Becker DP (1993) Concussive brain injury is associated with a prolonged accumulation of calcium: a 45Ca autoradiographic study. Brain Res 624:94-102
13. Flierl MA, Stahel PF, Beauchamp KM, Morgan SJ, Smith WR, Shohami E (2009) Mouse closed head injury model induced by a weight-drop device. Nat Protoc 4(9):1328-1337
14. Francke M, Pannicke T, Biedermann B, Faude F, Wiedemann P, Reichenbach A, Reichelt W (1997) Loss of inwardly rectifying potassium currents by human retinal glial cells in diseases of the eye. Glia 20:210-218
15. Gershkoff AM, Cifu DX, Means KM (1993) Geriatric rehabilitation. 1. Social, attitudinal, and economic factors. Arch Phys Med Rehabil 74(5-S):S402-S405
16. Giffard RG, Monyer H, Choi DW (1990) Selective vulnerability of cultured glia to injury by extracellular acidosis. Brain Res 530:138-141
17. Glimer LK, Ansari MA, Roberts KN, Scheff SW (2010) Age related mitochondrial changes after traumatic brain injury. J Neurotrauma 27:939-950
18. Goleburn G, Golden C (2001) Traumatic brain injury outcome in older adults: a critical review of the literature. J Clin Geropsychol 7:161-187
19. Gordon MN, Schreier WA, Ou X, Holcomb LA, Morgan DG (1997) Exaggerated astrocyte reactivity after nigrostriatal deafferentation in the aged rat. J Comp Neurol 388:106-119
20. Gupta RK, Kanungo M (2013) Glial molecular alterations with mouse brain development and aging: up-regulation of the Kir4.1 and aquaporin-4. Age (Dordr) 35:59-67
21. Haugeto O, Ullensvang K, Levy LM, Chaudhry FA, Honoré T, Nielsen M, Lehre KP, Danbolt NC (1996) Brain glutamate transporter proteins form homomultimers. J Biol Chem 271:27715-27722
22. Homayoun P, Rodriguez de Turco EB, Parkins NE, Lane DC, Soblosky J, Carey ME, Bazan NG (1997) Delayed phospholipid degradation in rat brain after traumatic brain injury. J Neurochem 69:199-205
23. Joh HD, Searles RV, Selmanoff M, Alkayed NJ, Koehler RC, Hurn PD, Murphy SJ (2006) Estradiol alters only GAD67 mRNA levels in ischemic rat brain with no consequent effects on GABA. J Cereb Blood Flow Metab 26:518-526
24. Kanungo MS (1994) Genes and aging. Cambridge University Press, Cambridge, pp 167-245
25. Katayama Y, Becker DP, Tamura T, Hovda DA (1990) Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury. J Neurosurg 73:889-900
26. Klein M, Houx PJ, Jolles J (1996) Long-term persisting cognitive sequelae of traumatic brain injury and the effect of age. J Nerv Ment Dis 184:459-467
27. Kucheryavykh YV, Kucheryavykh LY, Nichols CG, Maldonado HM, Baksi K, Reichenbach A, Skatchkov SN, Eaton MJ (2007) Downregulation of Kir4.1 inward rectifying potassium channel subunits by RNAi impairs potassium transfer and glutamate uptake by cultured cortical astrocytes. Glia 55:274-281
28. Lyeth BG, Gong QZ, Dhillon HS, Prasad MR (1996) Effects of muscarinic receptor antagonism on the phosphatidylinositol bisphosphate signal transduction pathway after experimental brain injury. Brain Res 742:63-70
29. MacFarlane SN, Sontheimer H (1997) Electrophysiological changes that accompany reactive gliosis in vitro. J Neurosci 17:7316-7329
30. Malenka RC, Kocsis JD, Ransom BR, Waxman SG (1981) Modulation of parallel fiber excitability by postsynaptically mediated changes in extracellular potassium. Science 214:339-341
31. Manzoni C, Mennini T (1997) Arachidonic acid inhibits 3H-glutamate uptake with different potencies in rodent central nervous system regions expressing different transporter subtypes. Pharmacol Res 35:149-151
32. Marcaggi P, Attwell D (2004) Role of glial amino acid transporters in synaptic transmission and brain energetics. Glia 47:217-225
33. McCullough LD, Hurn PD (2003) Estrogen and ischemic neuroprotection: an integrated view. Trends Endocrinol Metab 14:228-235
34. McCullough LD, Alkayed NJ, Traystman RJ, Williams MJ, Hurn PD (2001) Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke. Stroke 32:796-802
35. Mitani A, Tanaka K (2003) Functional changes of glial glutamate transporter GLT-1 during ischemia: an in vivo study in the hippocampal CA1 of normal mice and mutant mice lacking GLT-1. J Neurosci 23(18):7176-7182
36. Modi PK, Kanungo MS (2010) Age-dependent expression of S100β in the brain of mice. Cell Mol Neurobiol 30:709-716
37. 2+ levels following cortical compression contusion trauma in rats. J Cereb Blood Flow Metab 13:183-192
38. Olsen ML, Campbell SC, McFerrin MB, Floyd CL (2010) Sontheimer H (2010) Spinal cord injury causes a wide-spread, persistent loss of Kir4.1 and glutamate transporter 1: benefit of 17 beta-oestradiol treatment. Brain 133(Pt 4):1013-1025
39. Osteen CL, Moore AH, Prins ML, Hovda DA (2001) Age-dependency of 45calcium accumulation following lateral fluid percussion: acute and delayed patterns. J Neurotrauma 18:141-162
40. Pentland B, Jones PA, Roy CW, Miller JD (1986) Head injury in the elderly. Age Ageing 15(4):193-202
41. Pollen DA, Trachtenberg MC (1970) Neuroglia: gliosis and focal epilepsy. Science 167:1252
42. Prasad S, Pandey RS (2011) Aging: the current perspectives In: Singh MP, Agrawal A, Sharma B (eds) Recent Trends in Biotechnology, vol 2. Nova Biomedical, New York, pp 1-19
43. Prins ML, Lee SM, Cheng CLY, Becker DP, Hovda DA (1996) Fluid percussion brain injury in the developing and adult rat: a comparative study of mortality, morphology, intracranial pressure and mean arterial blood pressure. Dev Brain Res 95:272-282
44. Rao VLR, Mustafa KB, Aclan D, Jeffrey DR, Robert JD (1998) Traumatic brain injury down-regulates glial glutamate transporter (GLT-1 and GLAST) proteins in rat brain. J Neurochem 70:2020-2027
45. Rapoport MJ, Feinstein A (2000) Outcome following traumatic brain injury in the elderly: a critical review. Brain Inj 4:749-761
46. Rapoport M, Wolf U, Herrmann N, Kiss A, Shammi P, Reis M, Phillips A, Fein-stein A (2008) Traumatic brain injury, apolipoprotein E ε4, and cognition in older adults: a two year longitudinal study. J Neuropsychiatry Clin Neurosci 20:68-73
47. Reinert M, Khaldi A, Zauner A, Doppenberg E, Choi S, Bullock R (2000) High level of extracellular potassium and its correlates after severe head injury: relationship to high intracranial pressure. J Neurosurg 93(5):800-807
48. Rusa R, Alkayed NJ, Crain BJ, Traystman RJ, Kimes AS, London ED, Klaus JA, Hurn PD (1999) 17β-etaestradiol reduces stroke injury in estrogen-deficient female animals. Stoke 30:1665-1670
49. Sandhir R, Berman NEJ (2010) Age-dependent response of CCAAT/enhancer binding proteins following traumatic injury in mice. Neurochem Int 56:188-193
50. Sivanandam ST, Thakur MK (2012) Traumatic brain injury: a risk factor for Alzheimer's disease. Neurosci Biobehav Rev 36:1376-1381
51. Swanson RA, Farrell K, Simon RP (1995) Acidosis causes failure of astrocyte glutamate uptake during hypoxia. J Cereb Blood Flow Metab 15:417-424
52. Tatsuki I, Motohiro I, Shozo N, Masahiro T, Nobuyuki M, Shigeo H, Akihiko I, Takao S (2012) Increased apoptotic neuronal cell death and cognitive impairment at early phase after traumatic brain injury in aged rats. Brain Struct Funct. doi: 10.1007/s00429-012-0394-5
53. Tokutomi T, Miyagi T, Ogawa T, Ono J, Kawamata T, Sakamoto T, Shigemori M, Nakamura N (2008) Age associated increase in poor outcomes after traumatic brain injury: a report from the Japan neurotrauma data bank. J Neurotrauma 25:1407-1414
54. Topp KS, Faddis BT, Vijayan VK (1989) Trauma-induced proliferation of astrocytes in the brains of young and aged rats. Glia 2:201-211
55. Trotti D, Rizzini BL, Rossi D, Haugeto O, Racagni G, Danbolt NC, Volterra A (1997) Neuronal and glial glutamatetransporters possess an SF1-based redox regulatory mechanism. Eur J Neurosci 9:1236-1243
56. Vemuganti LRR, Mustafa KB, Aclan D, Jeffrey DR, Robert JD (1998) Brain injury down-regulates glial glutamate transporter (GLT-1 and GLAST) proteins in rat brain. J Neurochem 70(5):2020-2027
57. Yi JH, Hazell AS (2006) Excitotoxic mechanisms and the role of astrocytic glutamate transporters in traumatic brain injury. Neurochem Int 48:394-403