Buddlejasaponin IV induces cell cycle arrest at G2/M phase and apoptosis in immortalized human oral keratinocytes

Phytotherapy Research

Volumn 25, Issue 10, 2011, Pages 1503-1510

  Hwang, Young Sun ^a   Chung, Won Yoon ^a,b   Kim, Jin ^a,b   Park, Hee Juhn ^c   Kim, Eun Cheol ^d   Park, Kwang Kyun ^a,b  

^a Yonsei University College of Dentistry   (South Korea)

^b Yonsei University   (South Korea)

^c Sangji University   (South Korea)

^d Wonkwang University   (South Korea)

Author keywords

apoptosis; buddlejasaponin IV; cell cycle arrest; immortalized human oral keratinocyte; p53

Indexed keywords

BUDDLEJASAPONIN IV; CASPASE 3; CASPASE 9; CELL CYCLE PROTEIN; CHECKPOINT KINASE 2; CYCLIN B1; CYTOCHROME C; DEATH RECEPTOR; FAS LIGAND; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLANT MEDICINAL PRODUCT; PROCASPASE 8; PROTEIN BAX; PROTEIN BCL 2; PROTEIN CDC2; PROTEIN CDC25C; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL IMMORTALIZATION; CELL VIABILITY; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; KERATINOCYTE; MITOCHONDRION; MOUTH CANCER; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; WART VIRUS;

ALPHAPAPILLOMAVIRUS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APIACEAE; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CASPASES; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELL LINE; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA-BINDING PROTEINS; HUMANS; KERATINOCYTES; MITOCHONDRIA; MOUTH MUCOSA; MOUTH NEOPLASMS; NUCLEAR PROTEINS; PHOSPHORYLATION; PHYTOTHERAPY; PLANT EXTRACTS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; SALIVARY PROLINE-RICH PROTEINS; SAPONINS; TRITERPENES; TUMOR NECROSIS FACTORS; TUMOR SUPPRESSOR PROTEINS;

HUMAN PAPILLOMAVIRUS; PLEUROSPERMUM;

EID: 80053381201     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3406     Document Type: Article

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