The intellectual disability of trisomy 21: Differences in gene expression in a case series of patients with lower and higher IQ

European Journal of Human Genetics

Volumn 21, Issue 11, 2013, Pages 1253-1259

  Mégarbané, André ^a,b   Noguier, Florian ^c   Stora, Samantha ^a   Manchon, Laurent ^c   Mircher, Clotilde ^a   Bruno, Roman ^c   Dorison, Nathalie ^a   Pierrat, Fabien ^c   Rethoré, Marie Odile ^a   Trentin, Bernadette ^c   Ravel, Aimé ^a   Morent, Marine ^c   Lefranc, Gerard ^d   Piquemal, David ^c  

^a Institut Jerome Lejeune   (France)

^b Unite de Gene Tique Me Dicale   (Lebanon)

^c Skuldtech   (France)

^d UNIV MONTPELLIER   (France)

Author keywords

Down syndrome; gene expression; HLA; intellectual disability; Trisomy 21

Indexed keywords

COHESIN; HLA DQA1 ANTIGEN; HLA DRB1 ANTIGEN; SPACER DNA; TRANSCRIPTION FACTOR CTCF;

ADULT; ARTICLE; CASE STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE LIBRARY; GENETIC MARKER; HOUSEKEEPING GENE; HUMAN; INTELLECTUAL IMPAIRMENT; INTELLIGENCE QUOTIENT; MALE; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTOMICS; TRISOMY 21; UNINDEXED SEQUENCE;

ADOLESCENT; ADULT; CASE-CONTROL STUDIES; DOWN SYNDROME; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HLA-DQ ALPHA-CHAINS; HLA-DRB1 CHAINS; HUMANS; INTELLECTUAL DISABILITY; INTELLIGENCE TESTS; MALE; RNA, MESSENGER; YOUNG ADULT;

EID: 84885938984     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2013.24     Document Type: Article

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