BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers

Nucleic Acids Research

Volumn 41, Issue 18, 2013, Pages 8601-8614

  Buckley, Niamh E ^a   Nic An Tsaoir, Caoimhe B ^a   Blayney, Jaine K ^a   Oram, Lisa C ^a   Crawford, Nyree T ^a   D'Costa, Zenobia C ^a   Quinn, Jennifer E ^a   Kennedy, Richard D ^a   Harkin, D Paul ^a   Mullan, Paul B ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 1; ESTROGEN RECEPTOR ALPHA; GAMMA SECRETASE INHIBITOR; JAGGED1; NOTCH RECEPTOR; TAMOXIFEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST CANCER; BREAST CELL; CANCER STEM CELL; CANCER SUSCEPTIBILITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EMBRYO; ENHANCER REGION; ENZYME ACTIVITY; GENE; GENE ACTIVATION; GENE LOCATION; JAG1 GENE; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR GROWTH; UPREGULATION;

ANIMALS; BRCA1 PROTEIN; BREAST; BREAST NEOPLASMS; CALCIUM-BINDING PROTEINS; CELL DIFFERENTIATION; CELL LINE; EMBRYONIC STEM CELLS; ESTROGEN ANTAGONISTS; FEMALE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MCF-7 CELLS; MEMBRANE PROTEINS; MICE; RECEPTOR, NOTCH1; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TAMOXIFEN; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 84885913507     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt626     Document Type: Article

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